ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Blue cheese | Rheumatoid arthritis (ebi-a-GCST000679) | rs7671974 | -7.52587363425281 | 3.55665319417297 | 0.0343449157681547 |
| Blue cheese | Rheumatoid arthritis (ebi-a-GCST000679) | All - Inverse variance weighted | -4.96608119518364 | 2.2277139657773 | 0.0257987728562162 |
| Blue cheese | Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) | rs16934925 | 4.96867673476844 | 2.2623542307341 | 0.0280746470779299 |
| Blue cheese | Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) | All - MR Egger | 4.13297042283227 | 1.84510545561754 | 0.0387455542079766 |
| Blue cheese | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs10509498 | -2.73139051419792 | 1.07609205517967 | 0.0111408411273143 |
| Blue cheese | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs168389 | -2.06914762170622 | 0.983388096175143 | 0.0353696602496188 |
| Blue cheese | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs34065485 | -3.00242675182239 | 0.948256478425442 | 0.0015441259963096 |
| Blue cheese | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs79603758 | 2.16633957069165 | 0.978124859157526 | 0.0267745932837509 |
| Blue cheese | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | All - MR Egger | 0.99858607058165 | 0.454718082874835 | 0.0414329013245559 |
| Blue cheese | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs10509498 | -2.73101292937566 | 1.07569123436835 | 0.0111219198411661 |
| Blue cheese | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs168389 | -2.07574662041571 | 0.98930065257782 | 0.0358878394369231 |
| Blue cheese | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs34065485 | -3.00867129803844 | 0.9524925176123 | 0.0015845558920881 |
| Blue cheese | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs79603758 | 2.18884568581578 | 0.997185199146136 | 0.0281618588407199 |
| Blue cheese | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | All - MR Egger | 0.993020682357902 | 0.454422862038696 | 0.0423346082049139 |
| Blue cheese | Fracture of lower leg or ankle (ebi-a-GCST90038707) | All - Inverse variance weighted | -0.0123423795829511 | 0.0047480098568151 | 0.0093363805721102 |
| Blue cheese | Bicipital tendinitis (finn-b-M13_BICIPITALTEND) | rs142856921 | 22.3380701008231 | 8.56558504916064 | 0.0091103265684349 |
| Blue cheese | Bicipital tendinitis (finn-b-M13_BICIPITALTEND) | rs187716036 | 24.5827093901167 | 9.72175399258324 | 0.0114508986901034 |
| Blue cheese | Bicipital tendinitis (finn-b-M13_BICIPITALTEND) | rs34600782 | 27.0849162415428 | 10.2463909692825 | 0.0082087321415972 |
| Blue cheese | Bicipital tendinitis (finn-b-M13_BICIPITALTEND) | All - Inverse variance weighted | 4.40922356412983 | 2.12069274656828 | 0.0376042051656704 |
| Blue cheese | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | rs16934925 | 41.7859208963858 | 21.1099016533203 | 0.0477657577593636 |
| Blue cheese | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | All - Inverse variance weighted | 3.19417472155969 | 1.62295378516814 | 0.0490537418371928 |
| Blue cheese | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | rs34600782 | 24.0095517203951 | 10.8325192662542 | 0.0266618709206009 |
| Blue cheese | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | All - Inverse variance weighted | 4.03475892964475 | 1.82618915726851 | 0.0271477213033144 |
| Blue cheese | Drug-induced osteoporosis with pathological fracture (finn-b-OSTPOPATFRACTURE) | rs118051920 | 54.9231345347565 | 18.9244953753448 | 0.0037052287894183 |
| Blue cheese | Drug-induced osteoporosis with pathological fracture (finn-b-OSTPOPATFRACTURE) | All - Inverse variance weighted | 7.87815690214723 | 3.66326307663796 | 0.0315090074500448 |
| Blue cheese | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | rs10509498 | 41.563375434041 | 20.9269126486559 | 0.0470199178268321 |
| Blue cheese | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | All - Inverse variance weighted | 10.2010763371559 | 4.4314720255183 | 0.0213373644898822 |
| Blue cheese | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | rs10509498 | 9.57032299477045 | 3.44183087975811 | 0.0054260097203877 |
| Blue cheese | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | All - Inverse variance weighted | 1.69360800343289 | 0.808091788275644 | 0.0360989223373925 |
| Blue cheese | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | rs138371361 | 2.84533006749602 | 1.09270496658962 | 0.0092160882870421 |
| Blue cheese | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | rs78387684 | -5.24930654458537 | 2.42221046238648 | 0.0302230049200368 |
| Blue cheese | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | rs114872780 | 2.76160039196909 | 1.40585503825039 | 0.0494887711784385 |
| Blue cheese | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | rs138371361 | 2.3081857721219 | 0.997553691409068 | 0.0206761626416902 |
| Blue cheese | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | rs34600782 | 5.01465320742429 | 2.48200007236152 | 0.0433410673715192 |
| Blue cheese | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | rs59939687 | -4.51291328278357 | 1.96297294176514 | 0.0215038259150404 |
| Blue cheese | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | rs34065485 | -37.5371789330447 | 18.4889829195351 | 0.0423315659039765 |
| Blue cheese | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | rs118051920 | 43.5224232752692 | 20.4737976997878 | 0.0335230729076287 |
| Blue cheese | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | rs142013460 | 44.4099969289715 | 16.463637560141 | 0.0069870765626561 |
| Blue cheese | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | rs187716036 | 62.4897098370038 | 26.5192200644458 | 0.0184533731440995 |
| Blue cheese | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | All - Inverse variance weighted | 11.1920027142378 | 5.26611294788285 | 0.033562651361842 |
| Blue cheese | Rheumatoid arthritis (ieu-a-833) | rs7671974 | -5.93432737065007 | 2.07920755951635 | 0.0043154953113951 |
| Blue cheese | Rheumatoid arthritis (ieu-a-833) | All - Inverse variance weighted | -2.50705585811085 | 1.23098052746946 | 0.0416868093347134 |
| Blue cheese | Rheumatoid arthritis (ieu-a-834) | rs7671974 | -7.52587363425281 | 3.61580161742902 | 0.0373987213909692 |
| Blue cheese | Rheumatoid arthritis (ieu-a-834) | All - Inverse variance weighted | -4.93469463577971 | 2.23589947778203 | 0.0273120443955119 |
| Blue cheese | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | rs114872780 | 0.0684425910047548 | 0.0277435887442513 | 0.0136261912015729 |
| Blue cheese | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | rs78659091 | 0.0753185802395548 | 0.0301746779688667 | 0.0125572282343743 |
| Blue cheese | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | All - MR Egger | 0.030731455356456 | 0.0119212490300109 | 0.0189602043861639 |
| Blue cheese | Operation code: elbow surgery (ukb-b-10324) | rs7671974 | 0.0524714505168645 | 0.0233625933354335 | 0.0247065690613935 |
| Blue cheese | Operation code: elbow surgery (ukb-b-10324) | All - Inverse variance weighted | 0.0251994996263848 | 0.0092010072222814 | 0.0061668336008883 |
| Blue cheese | Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) | rs7671974 | -0.042759456997284 | 0.0192149059378303 | 0.0260592662047646 |
| Blue cheese | Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) | All - Inverse variance weighted | -0.0206128791276238 | 0.0104151390346799 | 0.0478017497365342 |
| Blue cheese | Operation code: knee surgery (not replacement) (ukb-b-1508) | rs34065485 | 0.118962100497583 | 0.0478534954895969 | 0.0129200781145251 |
| Blue cheese | Operation code: knee surgery (not replacement) (ukb-b-1508) | rs34600782 | 0.133866637722059 | 0.0537360975433265 | 0.0127317290027152 |
| Blue cheese | Operation code: knee surgery (not replacement) (ukb-b-1508) | All - Inverse variance weighted | 0.039404568569766 | 0.0156442086144924 | 0.0117756892130149 |
| Blue cheese | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | rs142856921 | -0.316523229341272 | 0.114912999424583 | 0.0058789124216138 |
| Blue cheese | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | All - MR Egger | -0.110694698690188 | 0.0495032441174791 | 0.0382463938663963 |
| Blue cheese | Fractured heel (right) (ukb-b-3499) | rs142856921 | 0.112241062270146 | 0.0554958594981362 | 0.0431234470666443 |
| Blue cheese | Fractured heel (right) (ukb-b-3499) | rs182674396 | 0.114289372734449 | 0.0573919333845516 | 0.0464386967340994 |
| Blue cheese | Fractured heel (right) (ukb-b-3499) | All - Inverse variance weighted | 0.0317530559225317 | 0.015318453118457 | 0.0381850237856663 |
| Blue cheese | Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) | rs168389 | -0.0544108952122937 | 0.0222465883817351 | 0.0144527738617068 |
| Blue cheese | Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) | All - Inverse variance weighted | -0.010382912737585 | 0.0052289531670055 | 0.0470713104973753 |
| Blue cheese | Fractured/broken bones in last 5 years (ukb-e-2463_AFR) | rs16934925 | -3.5795298846025 | 1.73172365496453 | 0.0387310476393957 |
| Blue cheese | Fractured/broken bones in last 5 years (ukb-e-2463_AFR) | All - Inverse variance weighted | -3.49246623482453 | 1.5871546224738 | 0.0277744546890705 |
| Blue cheese | Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) | rs10509498 | 13.7164947929601 | 6.55981016196937 | 0.0365289967269794 |
| Blue cheese | Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) | rs59939687 | 9.43574150340634 | 3.99330279819868 | 0.0181329742924145 |
| Blue cheese | Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) | All - Inverse variance weighted | 6.73586586599503 | 2.67873524437775 | 0.0119177820017528 |
| Blue cheese | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) | rs10509498 | 12.9177576689656 | 6.5147904331624 | 0.0473858085564699 |
| Blue cheese | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) | rs59939687 | 9.21057696008622 | 3.96636003233132 | 0.0202235844111283 |
| Blue cheese | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) | All - Inverse variance weighted | 6.49608116363398 | 2.80943799509599 | 0.0207647305873105 |
| Blue cheese | Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) | rs10509498 | 16.1199674115253 | 6.41022848238494 | 0.0119124968156512 |
| Blue cheese | Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) | rs59939687 | 10.7482390978022 | 3.89804087602479 | 0.0058273035178996 |
| Blue cheese | Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) | All - Inverse variance weighted | 7.2959469581763 | 3.08644777388147 | 0.0180853842841802 |
| Blue cheese | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) | rs10509498 | 15.4374102328391 | 6.43491672076295 | 0.0164396005904595 |
| Blue cheese | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) | rs59939687 | 10.690504599515 | 3.91439898387283 | 0.0063128720561093 |
| Blue cheese | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) | All - Inverse variance weighted | 7.1626535138286 | 3.17914271481996 | 0.0242582569456192 |
| Blue cheese | M75 Shoulder lesions (ukb-e-M75_CSA) | All - Inverse variance weighted | 5.42141790060443 | 2.72804389341071 | 0.0468901250078936 |