ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Couscous | Total body bone mineral density (ebi-a-GCST005348) | rs11839514 | -1.96071094480823 | 0.883068288119738 | 0.0263957655841366 |
| Couscous | Total body bone mineral density (ebi-a-GCST005348) | rs143108349 | 2.33926565607642 | 0.932614721915931 | 0.0121317985061587 |
| Couscous | Total body bone mineral density (ebi-a-GCST005348) | rs75745052 | 1.43909866978051 | 0.678522399128967 | 0.0339276740385864 |
| Couscous | Total body bone mineral density (ebi-a-GCST005348) | All - MR Egger | 1.36379227147424 | 0.434155815602901 | 0.0067256269366796 |
| Couscous | Total body bone mineral density (age 45-60) (ebi-a-GCST005350) | rs11839514 | -3.60710944808232 | 1.66136576239476 | 0.0299182357013621 |
| Couscous | Total body bone mineral density (age 45-60) (ebi-a-GCST005350) | All - MR Egger | 1.75394319005719 | 0.762686188887115 | 0.0362458801048961 |
| Couscous | Frozen shoulder (ebi-a-GCST90000512) | rs11839514 | 4.71859307764266 | 2.17611973807297 | 0.0301319325845676 |
| Couscous | Achilles tendon injury (ebi-a-GCST90018567) | rs11839514 | 25.484901777362 | 12.2151094480823 | 0.0369476110137794 |
| Couscous | Achilles tendon injury (ebi-a-GCST90018567) | rs13143749 | 15.2266449361667 | 7.19321339768905 | 0.0342762255593032 |
| Couscous | Achilles tendon injury (ebi-a-GCST90018567) | rs79835743 | -21.3792929304019 | 9.48530945548044 | 0.0242001117413218 |
| Couscous | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | rs2533014 | -37.9665551047705 | 17.4001047557327 | 0.0291115410385165 |
| Couscous | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | rs4603139 | -41.208161393856 | 18.7318508329512 | 0.027814131859816 |
| Couscous | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | All - Inverse variance weighted | -9.59483264539659 | 4.33213088249196 | 0.0267733329115692 |
| Couscous | Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) | rs79835743 | 17.0498584850767 | 7.80582703341245 | 0.0289440634222233 |
| Couscous | Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) | All - MR Egger | -7.96141887192948 | 3.40521024550524 | 0.0336529130894679 |
| Couscous | Infective bursitis (finn-b-M13_INFBURSA) | All - Inverse variance weighted | -5.35032603032647 | 2.70069799947432 | 0.0475811719586302 |
| Couscous | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | rs11839514 | 21.3133769878391 | 9.72871842843779 | 0.0284684963000664 |
| Couscous | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | All - Inverse variance weighted | 5.31663380901209 | 2.53197274240721 | 0.0357465270808372 |
| Couscous | Osteoporosis (finn-b-M13_OSTEOPOROSIS) | rs7912809 | -12.4399580219919 | 5.75690568374558 | 0.030704936787553 |
| Couscous | Osteoporosis (finn-b-M13_OSTEOPOROSIS) | All - Inverse variance weighted | -2.35777387621675 | 0.984893609390363 | 0.0166685828174656 |
| Couscous | Other shoulder lesions (finn-b-M13_SHOULDERNAS) | rs75745052 | 14.3815189433986 | 5.95521752165749 | 0.0157376136927141 |
| Couscous | Other shoulder lesions (finn-b-M13_SHOULDERNAS) | All - MR Egger | 6.73409767823086 | 2.91041740928009 | 0.0352707284689229 |
| Couscous | Burn and corrosion of hip and lower limb, except ankle and foot (finn-b-ST19_BURN_CORROSION_HIP_LOWER_LIMB_ANKLE_FOOT) | rs56200810 | -25.7635432271783 | 12.9723819649157 | 0.0470299631643337 |
| Couscous | Burn and corrosion of hip and lower limb, except ankle and foot (finn-b-ST19_BURN_CORROSION_HIP_LOWER_LIMB_ANKLE_FOOT) | All - MR Egger | 13.4360469942251 | 5.91629800669592 | 0.0383072432619643 |
| Couscous | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | All - Inverse variance weighted | -7.08688318038382 | 3.10071554061225 | 0.0222797902371215 |
| Couscous | Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) | All - Inverse variance weighted | 1.77290292817356 | 0.832277700608304 | 0.0331565953556757 |
| Couscous | Fracture of foot, except ankle (finn-b-ST19_FRACT_FOOT_ANKLE) | rs143108349 | 7.96844567648059 | 3.35689774214491 | 0.017608330995379 |
| Couscous | Fracture of foot, except ankle (finn-b-ST19_FRACT_FOOT_ANKLE) | All - Inverse variance weighted | 1.9276032780399 | 0.923714824971715 | 0.0369066889030931 |
| Couscous | Fracture of rib(s), sternum and thoracic spine (finn-b-ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE) | rs140097236 | 5.23822143857732 | 2.32299030239438 | 0.0241366171918793 |
| Couscous | Fracture of rib(s), sternum and thoracic spine (finn-b-ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE) | rs61866889 | 7.51167847519169 | 3.80785917163457 | 0.0485323061109918 |
| Couscous | Fracture of rib(s), sternum and thoracic spine (finn-b-ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE) | All - MR Egger | 3.4582541710683 | 1.44670994261966 | 0.0303879517972052 |
| Couscous | Injuries to the ankle and foot (finn-b-ST19_INJURI_ANKLE_FOOT) | rs140097236 | 3.48313330556923 | 1.40623394324223 | 0.0132520459791635 |
| Couscous | Injuries to the ankle and foot (finn-b-ST19_INJURI_ANKLE_FOOT) | All - Inverse variance weighted | 1.05538183540235 | 0.518909613480031 | 0.0419672039043809 |
| Couscous | Injuries to the ankle and foot (finn-b-ST19_INJURI_ANKLE_FOOT) | All - MR Egger | 2.22548882251307 | 0.872827673543356 | 0.0222091521504839 |
| Couscous | Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) | All - MR Egger | 10.1632647116234 | 3.85934251221892 | 0.0188038089297531 |
| Couscous | Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) | rs117477328 | -6.60253576665895 | 2.4803362311519 | 0.0077688977090379 |
| Couscous | Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) | All - MR Egger | -2.87967114567226 | 1.1860031635095 | 0.0282317469729687 |
| Couscous | Sequelae of injuries of neck and trunk (finn-b-ST19_SEQUEL_INJURI_NECK_TRUNK) | All - Inverse variance weighted | 5.91695778045812 | 2.82397230451114 | 0.036147836792296 |
| Couscous | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs2533014 | -37.6410429409728 | 19.0276655747213 | 0.0479030972641944 |
| Couscous | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs56200810 | -40.4273184168559 | 19.0885806794568 | 0.0341852532671037 |
| Couscous | Bone sialoprotein 2 (prot-a-1396) | rs13143749 | -8.47489500407447 | 3.88223740571261 | 0.0290363649120881 |
| Couscous | Bone sialoprotein 2 (prot-a-1396) | All - MR Egger | -3.43194933756026 | 1.54709249930992 | 0.0435760379958649 |
| Couscous | Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) | rs56200810 | 0.0427700490504035 | 0.0204767312617793 | 0.036733415193143 |
| Couscous | Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) | All - Inverse variance weighted | 0.025973900201498 | 0.0117834253163464 | 0.0275050675051595 |
| Couscous | Ankle spacing width (ukb-b-4080) | All - Inverse variance weighted | 0.187306473522926 | 0.081585375516736 | 0.0216853784566451 |
| Couscous | Operative procedures - secondary OPCS: Y76.7 Arthroscopic approach to joint (ukb-b-4455) | All - Inverse variance weighted | -0.0291064802052901 | 0.0127139649624773 | 0.022060100062324 |
| Couscous | Spondylosis and allied disorders (ukb-e-721_CSA) | All - Inverse variance weighted | -8.71737764597713 | 3.56774475413803 | 0.0145501649592824 |
| Couscous | Other disorders of synovium, tendon, and bursa (ukb-e-727_AFR) | rs56200810 | -39.2946890252742 | 15.735997680375 | 0.0125206253317608 |
| Couscous | Other disorders of synovium, tendon, and bursa (ukb-e-727_AFR) | All - Inverse variance weighted | -6.67448894202234 | 2.96967118218286 | 0.0246048026827157 |