ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Other meat | Osteoarthritis (Firth correction) (ebi-a-GCST90013881) | rs150772606 | 2.50888606702729 | 1.22094057495119 | 0.0398906205331119 |
| Other meat | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs138358390 | 2.65653394678815 | 1.16923416929947 | 0.023084758490561 |
| Other meat | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | All - MR Egger | 1.62887855124903 | 0.687768491137685 | 0.0292634775859772 |
| Other meat | Osteoarthritis (SPA correction) (ebi-a-GCST90013931) | rs150772606 | 2.54932228705045 | 1.25950839938914 | 0.0429638384451992 |
| Other meat | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs138358390 | 2.68340105780774 | 1.19113872550743 | 0.0242715643017605 |
| Other meat | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | All - MR Egger | 1.62440383643558 | 0.687925941862591 | 0.0296877558341431 |
| Other meat | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | rs79932756 | -43.5434857868216 | 18.1655575643343 | 0.0165283237083347 |
| Other meat | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | All - Inverse variance weighted | -6.05526462519285 | 2.76097427776313 | 0.0282956895815136 |
| Other meat | Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) | rs74883734 | 5.45087564510086 | 2.59853273546937 | 0.0359339161630593 |
| Other meat | Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) | All - Inverse variance weighted | 1.0512452393903 | 0.477321981375605 | 0.0276383511440434 |
| Other meat | Joint disorder (ebi-a-GCST90038654) | All - Inverse variance weighted | -0.0576758666786698 | 0.0221684799123521 | 0.0092761342457776 |
| Other meat | Rheumatoid arthritis (ebi-a-GCST90038685) | All - Inverse variance weighted | -0.0195412078831568 | 0.0071935874336366 | 0.0065980971431927 |
| Other meat | Fractures (ebi-a-GCST90038703) | All - Inverse variance weighted | -0.0218903158870104 | 0.0090028683052706 | 0.0150371786192747 |
| Other meat | Fracture of upper limb or shoulder (ebi-a-GCST90038704) | rs117236237 | -0.0744108172845285 | 0.0322903101468827 | 0.0211984170687181 |
| Other meat | Fracture of upper limb or shoulder (ebi-a-GCST90038704) | All - Inverse variance weighted | -0.0159054728322226 | 0.006402313091172 | 0.0129794647645158 |
| Other meat | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs71571162 | 70.0970659607324 | 20.3215634367579 | 0.0005618476009894 |
| Other meat | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs75788396 | 46.9911924476557 | 20.1641966844224 | 0.0197835834896174 |
| Other meat | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | All - Inverse variance weighted | 8.51806163011678 | 3.77604543411642 | 0.024082191345567 |
| Other meat | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs71571162 | 69.7953569250334 | 20.2729006890645 | 0.0005757443999704 |
| Other meat | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs75788396 | 47.8438197704059 | 20.2433064360178 | 0.0181062075122196 |
| Other meat | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | All - Inverse variance weighted | 8.48575448440013 | 3.77845623193857 | 0.0247151681592301 |
| Other meat | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | rs34564636 | -10.5759195788237 | 5.33737997435964 | 0.0475373040905203 |
| Other meat | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | rs76220040 | -6.9641129457144 | 3.31122655878305 | 0.0354498407098601 |
| Other meat | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | All - MR Egger | -6.91171902262443 | 2.55065214086985 | 0.0124981647973579 |
| Other meat | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs2826909 | -26.5065349208187 | 12.3887605075182 | 0.0323900908251748 |
| Other meat | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs3899492 | -45.8017885161147 | 17.7222569941612 | 0.009754240239304 |
| Other meat | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | All - Inverse variance weighted | -6.10896171805994 | 2.48682723819262 | 0.0140286716067006 |
| Other meat | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | rs115840307 | 21.7865615516858 | 9.68442825585035 | 0.0244712536458987 |
| Other meat | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | rs117236237 | 121.398482992167 | 45.5240009360847 | 0.007660186817916 |
| Other meat | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | rs187792833 | 30.3406638897742 | 15.4267731996908 | 0.0492116080576264 |
| Other meat | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | All - Inverse variance weighted | 4.83224772000385 | 2.25862648836251 | 0.0323981923619079 |
| Other meat | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | rs118134155 | -20.6895573748795 | 10.0493486358222 | 0.0395137983679919 |
| Other meat | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | rs8087954 | 26.633514377748 | 12.820060661635 | 0.0377565977963025 |
| Other meat | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | All - Inverse variance weighted | 8.26191469958651 | 4.12137659188929 | 0.0450005522196235 |
| Other meat | Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) | All - MR Egger | -9.04850629238446 | 3.81815629508286 | 0.0265627499495664 |
| Other meat | Other specific joint derangements/joint disorders (finn-b-M13_JOINTOTH) | rs111907711 | -4.19879831574963 | 1.64797905726136 | 0.0108390031147983 |
| Other meat | Other specific joint derangements/joint disorders (finn-b-M13_JOINTOTH) | All - MR Egger | -2.09953346895433 | 0.915424494759515 | 0.031289723379128 |
| Other meat | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | rs115840307 | -15.3136439305624 | 6.87208843447929 | 0.0258549965229047 |
| Other meat | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | All - MR Egger | -7.89610115226458 | 3.49588320041567 | 0.0336912029147037 |
| Other meat | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs111396524 | -16.5917157376785 | 5.94397838186658 | 0.0052488907122351 |
| Other meat | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs4655716 | 14.0064773449134 | 6.17534651712539 | 0.0233213963596302 |
| Other meat | Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) | rs4655716 | -27.2735793058202 | 13.7773751132494 | 0.0477494110087604 |
| Other meat | Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) | All - Inverse variance weighted | -5.3592804223338 | 2.60219877010224 | 0.0394444506864269 |
| Other meat | Other congenital malformations of face and neck (finn-b-Q17_OTHER_CONGEN_MALFO_FACE_NECK) | rs117236237 | 94.4309844031772 | 41.4079814985615 | 0.0225779326223917 |
| Other meat | Other congenital malformations of face and neck (finn-b-Q17_OTHER_CONGEN_MALFO_FACE_NECK) | rs76220040 | -17.5268298757572 | 6.50750214734799 | 0.0070742892393303 |
| Other meat | Other congenital malformations of face and neck (finn-b-Q17_OTHER_CONGEN_MALFO_FACE_NECK) | All - MR Egger | -10.6769093977391 | 4.94716518623312 | 0.0415922252968198 |
| Other meat | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | rs76220040 | 3.03981454576805 | 1.33151540502655 | 0.0224319222461216 |
| Other meat | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | All - Inverse variance weighted | 1.00819439395836 | 0.474595276992289 | 0.0336430149911035 |
| Other meat | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | rs113735393 | 7.7815692193276 | 3.67478180983004 | 0.0342123891825683 |
| Other meat | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | rs150772606 | 6.08347364946885 | 2.46415645295727 | 0.0135572467809899 |
| Other meat | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | rs8087954 | 2.75093461240037 | 1.35783310996685 | 0.0427674464210303 |
| Other meat | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | All - Inverse variance weighted | 1.25216732015287 | 0.432175135254312 | 0.0037631662763013 |
| Other meat | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | rs117236237 | 96.2997122916179 | 48.1877125118731 | 0.0456701923363037 |
| Other meat | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | rs2826909 | -34.3697894662459 | 14.4485422909284 | 0.0173704109925065 |
| Other meat | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | rs74883734 | 30.8560654588525 | 15.5549378165073 | 0.0472911916984588 |
| Other meat | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | rs74938873 | 53.4615300378896 | 20.3377209312512 | 0.0085714874375522 |
| Other meat | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | All - MR Egger | 16.6592466682917 | 6.75541914674599 | 0.0215442432370334 |
| Other meat | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | rs117236237 | 363.049433531104 | 124.561210302438 | 0.003561141862399 |
| Other meat | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | rs138358390 | 57.8629872771748 | 25.8977050695411 | 0.0254639881956386 |
| Other meat | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | rs75480065 | 51.8567282085041 | 23.2502468655555 | 0.0257226752275368 |
| Other meat | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | All - Inverse variance weighted | 10.6310864273439 | 5.1529907628775 | 0.0391040280586385 |
| Other meat | Superficial injury of shoulder and upper arm (finn-b-ST19_SUPERF_INJURY_SHOUL_UPPER_ARM) | rs3899492 | -20.5687927087531 | 8.75395471264565 | 0.0187907077061919 |
| Other meat | Superficial injury of shoulder and upper arm (finn-b-ST19_SUPERF_INJURY_SHOUL_UPPER_ARM) | All - Inverse variance weighted | -2.81085925858307 | 1.25094145134359 | 0.0246403429724544 |
| Other meat | Hip osteoarthritis (ieu-a-1169) | All - Inverse variance weighted | -5.03828952982937 | 2.55640681784241 | 0.0487412525876642 |
| Other meat | Alkaline phosphatase, bone (prot-c-2795_23_3) | All - Inverse variance weighted | -10.3353619337737 | 4.68039064394972 | 0.0272284986512087 |
| Other meat | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | rs111907711 | -0.0405174181135765 | 0.0193959249972402 | 0.0367108290985191 |
| Other meat | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | rs144586390 | -0.0396738396940841 | 0.019220479074137 | 0.0390040497517072 |
| Other meat | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | All - MR Egger | -0.0253363318385146 | 0.0088299748399271 | 0.0086664481001399 |
| Other meat | Diagnoses - main ICD10: M25 Other joint disorders not elsewhere classified (ukb-a-568) | rs74883734 | -0.092957976286878 | 0.0466297634730901 | 0.0462031042727715 |
| Other meat | Diagnoses - main ICD10: M25 Other joint disorders not elsewhere classified (ukb-a-568) | rs75788396 | -0.0882609918604855 | 0.0439657718474764 | 0.0446971646631443 |
| Other meat | Diagnoses - main ICD10: M25 Other joint disorders not elsewhere classified (ukb-a-568) | All - Inverse variance weighted | -0.0199247710988181 | 0.0092813680874643 | 0.0318132399951266 |
| Other meat | Diagnoses - secondary ICD10: G55.1 Nerve root and plexus compressions in intervertebral disk disorders (ukb-b-1220) | rs2826909 | -0.0465960226666206 | 0.0230161820666678 | 0.042919794541986 |
| Other meat | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | rs150772606 | 0.190453002019434 | 0.0896690030934813 | 0.0336738370968811 |
| Other meat | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | rs74883734 | 0.255930093426316 | 0.0918949951050895 | 0.0053523174625645 |
| Other meat | Operative procedures - secondary OPCS: Z48.2 Skin of neck (ukb-b-14873) | All - Inverse variance weighted | 0.0379433104099521 | 0.0187364122810461 | 0.0428559906585978 |
| Other meat | Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) | rs75788396 | -0.0881212312993337 | 0.0325532232828789 | 0.0067896419350364 |
| Other meat | Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) | All - Inverse variance weighted | -0.0457037684050522 | 0.0215223829937547 | 0.0337081325387078 |
| Other meat | Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133) | All - Inverse variance weighted | -0.0368290836533666 | 0.0166277018953999 | 0.0267653324214311 |
| Other meat | Ankle spacing width (left) (ukb-b-2122) | rs3899492 | -1.02900551301947 | 0.479681565251687 | 0.0319380893476931 |
| Other meat | Ankle spacing width (left) (ukb-b-2122) | All - Inverse variance weighted | -0.250740323896361 | 0.0977389452813724 | 0.010305438914236 |
| Other meat | Non-cancer illness code, self-reported: joint pain (ukb-b-4122) | rs2826909 | 0.0431131872642339 | 0.0189474364737739 | 0.0228813434017344 |
| Other meat | Ankle spacing width (right) (ukb-b-8607) | rs3899492 | -0.995472979345468 | 0.485518678247151 | 0.0403323458691303 |
| Other meat | Ankle spacing width (right) (ukb-b-8607) | rs75788396 | -1.0719371341174 | 0.470267918358736 | 0.0226422323311209 |
| Other meat | Ankle spacing width (right) (ukb-b-8607) | All - Inverse variance weighted | -0.215528329141237 | 0.0989418079386717 | 0.0293811609276082 |
| Other meat | Fractured bone site(s): Wrist (ukb-b-9571) | rs113735393 | -0.107240195113415 | 0.0410852636874686 | 0.0090492908458559 |
| Other meat | Fractured bone site(s): Wrist (ukb-b-9571) | rs2826909 | 0.120038970469946 | 0.045703400444131 | 0.0086273598802676 |
| Other meat | Fractured bone site(s): Wrist (ukb-b-9571) | All - MR Egger | -0.177438130979232 | 0.0581749795177805 | 0.0225097171079423 |
| Other meat | Other specific joint derangements/joint disorders (ukb-d-M13_JOINTOTH) | rs75788396 | -0.113003885167801 | 0.052225972610446 | 0.0304836341057966 |
| Other meat | Other specific joint derangements/joint disorders (ukb-d-M13_JOINTOTH) | All - Inverse variance weighted | -0.0219597352172358 | 0.0109792774402152 | 0.0454886564523238 |
| Other meat | Diagnoses - main ICD10: M25 Other joint disorders, not elsewhere classified (ukb-d-M25) | rs75788396 | -0.12020814654642 | 0.0511284566566461 | 0.0187179710585882 |
| Other meat | Diagnoses - main ICD10: M25 Other joint disorders, not elsewhere classified (ukb-d-M25) | All - Inverse variance weighted | -0.0226886802938641 | 0.0107485618720644 | 0.0347845792234296 |
| Other meat | Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) | rs111396524 | -0.0427769319190127 | 0.0212586714527708 | 0.0441977025260386 |
| Other meat | Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) | rs187792833 | 0.05200518744024 | 0.0213995098308587 | 0.0150903011380199 |
| Other meat | Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) | rs2826909 | 0.0553717455071949 | 0.0206161604164067 | 0.0072347333656832 |
| Other meat | Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) | All - MR Egger | -0.0247634160048285 | 0.0109483075616774 | 0.0356239329677397 |
| Other meat | Ankle spacing width (left) (ukb-e-4100_CSA) | All - MR Egger | -3.01052160775838 | 1.39166511436502 | 0.0483087692489783 |