ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Spinach | Osteoprotegerin levels (ebi-a-GCST90012002) | All - MR Egger | -0.784872124578976 | 0.346590174204251 | 0.0412822330486444 |
| Spinach | Arthritis (not osteoarthritis) (ebi-a-GCST90038699) | All - Inverse variance weighted | -0.0074841599078534 | 0.0034823703494402 | 0.0316219726573939 |
| Spinach | Arthritis (not osteoarthritis) (ebi-a-GCST90038699) | All - MR Egger | -0.0203975289376906 | 0.006947424648289 | 0.013544675342058 |
| Spinach | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | rs111686396 | 21.6403720993628 | 8.15892595495281 | 0.0079932334328343 |
| Spinach | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | rs117367361 | -13.758758777829 | 5.9858792688921 | 0.0215313034037473 |
| Spinach | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | rs12529199 | 8.07649159067316 | 3.16542609893819 | 0.0107269377603948 |
| Spinach | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | rs76334742 | 8.49878606376554 | 3.09584550350624 | 0.0060469804904786 |
| Spinach | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | All - Inverse variance weighted | 1.85694696447432 | 0.833231528635305 | 0.0258399572287688 |
| Spinach | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | rs111686396 | 7.28660510443998 | 2.70964664190548 | 0.0071637482527164 |
| Spinach | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | rs117367361 | 5.04665632822889 | 2.07657810410324 | 0.015087360926469 |
| Spinach | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | All - Inverse variance weighted | 2.00858615539444 | 1.00067510502526 | 0.0447250654695811 |
| Spinach | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | All - MR Egger | 4.03232747348078 | 1.70204945999789 | 0.0354593790158295 |
| Spinach | Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) | All - Inverse variance weighted | -2.62742037196014 | 1.01681782334753 | 0.0097672066136801 |
| Spinach | Other/unspecified synovitis and tenosynovitis (finn-b-M13_TENDOSYNOVITISNAS) | All - MR Egger | -2.91125438138889 | 1.00601320394106 | 0.0134793275743319 |
| Spinach | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | rs11921267 | -2.58989685065991 | 0.886688823255487 | 0.003490629407947 |
| Spinach | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | rs1218593 | -1.88606529316904 | 0.822462262546317 | 0.0218368547040121 |
| Spinach | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | All - Inverse variance weighted | -0.640433475257759 | 0.223148418007892 | 0.004104862520195 |
| Spinach | Postmenopausal osteoporosis with pathological fracture (finn-b-OSTPOPATFRCTURE_POSTEMENO) | rs111686396 | 8.89903567655979 | 3.18669710702968 | 0.005229313359994 |
| Spinach | Postmenopausal osteoporosis with pathological fracture (finn-b-OSTPOPATFRCTURE_POSTEMENO) | All - Inverse variance weighted | 2.11240432137677 | 1.04456309219806 | 0.0431469125623161 |
| Spinach | Burn and corrosion of wrist and hand (finn-b-ST19_BURN_CORROSION_WRIST_HAND) | All - Inverse variance weighted | 2.82235835588772 | 1.18529473176568 | 0.0172589275383745 |
| Spinach | Forearm bone mineral density (ieu-a-977) | rs6850702 | -2.96238196863847 | 1.14672065860436 | 0.0097845718891647 |
| Spinach | Forearm bone mineral density (ieu-a-977) | All - Inverse variance weighted | -0.755458334016074 | 0.327189218981229 | 0.0209472402262981 |
| Spinach | Alkaline phosphatase, bone (prot-c-2795_23_3) | rs12529199 | 8.03459624524604 | 3.2780873378301 | 0.0142459448608375 |
| Spinach | Alkaline phosphatase, bone (prot-c-2795_23_3) | All - Inverse variance weighted | 6.02492155579792 | 1.6384179326423 | 0.0002357342015943 |
| Spinach | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | All - Inverse variance weighted | -0.0085749217620604 | 0.004030978756676 | 0.0333988593454524 |
| Spinach | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | All - MR Egger | -0.020911557961432 | 0.0075882404496905 | 0.0163560402880258 |
| Spinach | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | rs11921267 | -0.095033904684141 | 0.0420277106204908 | 0.0237456300510015 |
| Spinach | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | All - MR Egger | 0.0614268348938883 | 0.0251404304453756 | 0.0346498984608002 |
| Spinach | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | All - Inverse variance weighted | 0.0387259860516618 | 0.0164393492632086 | 0.0184884139485541 |
| Spinach | Ankle spacing width (left) (ukb-b-2122) | rs1218593 | -0.472689731494061 | 0.234102471908177 | 0.0434708655613761 |
| Spinach | Ankle spacing width (left) (ukb-b-2122) | rs184423582 | -0.747935887318076 | 0.215058307928356 | 0.0005054934528472 |
| Spinach | Ankle spacing width (left) (ukb-b-2122) | rs76334742 | -0.50795528770905 | 0.233549500252647 | 0.0296348896546434 |
| Spinach | Ankle spacing width (left) (ukb-b-2122) | All - Inverse variance weighted | -0.144148860639344 | 0.0718746913102475 | 0.0449034290120299 |
| Spinach | Ankle spacing width (left) (ukb-b-2122) | All - MR Egger | -0.316668627730184 | 0.12813961351483 | 0.0280671101977716 |
| Spinach | Ankle spacing width (right) (ukb-b-8607) | rs184423582 | -0.543421479591224 | 0.217534041334332 | 0.0124861466414418 |
| Spinach | Ankle spacing width (right) (ukb-b-8607) | rs72741427 | -0.496720798389563 | 0.232640741293992 | 0.0327494897910679 |
| Spinach | Ankle spacing width (right) (ukb-b-8607) | rs76334742 | -0.473134420330043 | 0.236524075374965 | 0.0454608930252143 |
| Spinach | Ankle spacing width (right) (ukb-b-8607) | All - Inverse variance weighted | -0.137243184290605 | 0.0675901318143496 | 0.0423036053994016 |
| Spinach | Ankle spacing width (right) (ukb-b-8607) | All - MR Egger | -0.374499853520513 | 0.109727315198588 | 0.0046253070115418 |
| Spinach | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | rs1774075 | -0.0372298303173097 | 0.0185774468502008 | 0.045066446140448 |
| Spinach | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | rs184423582 | -0.0409249147714754 | 0.0193182318936957 | 0.034136071125964 |
| Spinach | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | All - Inverse variance weighted | -0.0126318547962518 | 0.0051673288557903 | 0.0145028226207365 |
| Spinach | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | All - MR Egger | -0.0278888647230101 | 0.0097270251447179 | 0.0132150965318439 |
| Spinach | Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) | rs4748951 | 0.0200442850140585 | 0.0090112931663053 | 0.0261247927512655 |
| Spinach | Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) | All - Inverse variance weighted | 0.0066116237293073 | 0.0026058747264874 | 0.0111743294710406 |
| Spinach | Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) | rs191235830 | 0.0416103167497038 | 0.0192193957238149 | 0.0303863902773664 |
| Spinach | Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) | All - MR Egger | 0.022115402222653 | 0.0093893742148274 | 0.0348754938296529 |
| Spinach | Heel bone mineral density (BMD) (left) (ukb-e-4105_CSA) | rs76334742 | 3.28810342490233 | 1.65662242269629 | 0.0471640911605317 |
| Spinach | Heel bone mineral density (BMD) (left) (ukb-e-4105_CSA) | All - Inverse variance weighted | 0.586299615535796 | 0.298508289008526 | 0.0495186962269429 |
| Spinach | Heel bone mineral density (BMD) (left) (ukb-e-4105_CSA) | All - MR Egger | 1.373348537773 | 0.568884211163376 | 0.0364266183954344 |
| Spinach | Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) | rs111686396 | -1.45432241796436 | 0.639520223532218 | 0.0229609637688951 |
| Spinach | Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) | All - Inverse variance weighted | -1.02058679683205 | 0.494591991724031 | 0.0390658728205915 |
| Spinach | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_CSA) | rs4748951 | 1.88991662419435 | 0.956907462366273 | 0.0482652560634666 |
| Spinach | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_CSA) | All - Inverse variance weighted | 0.606594654491653 | 0.300053391163322 | 0.0432153769189639 |
| Spinach | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_CSA) | All - MR Egger | 1.35996909738976 | 0.572255085527834 | 0.0388432712233319 |
| Spinach | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) | rs111686396 | -1.46658942992469 | 0.635158619279654 | 0.0209428667750231 |
| Spinach | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) | All - Inverse variance weighted | -0.998965162330185 | 0.491200022460225 | 0.0419794539856117 |
| Spinach | Heel bone mineral density (BMD) (right) (ukb-e-4124_AFR) | rs111686396 | -0.950011926261628 | 0.450335639077248 | 0.0348959137472171 |
| Spinach | Heel bone mineral density (BMD) (right) (ukb-e-4124_AFR) | All - Inverse variance weighted | -0.828277646059237 | 0.375037706157431 | 0.0272081619297952 |
| Spinach | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) | rs111686396 | -0.971956247657341 | 0.442975431901046 | 0.0282243513220429 |
| Spinach | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) | All - Inverse variance weighted | -0.799882490832183 | 0.368818995404466 | 0.0301003727239058 |