ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Other egg | Bone mineral density (paediatric, total body less head) (ebi-a-GCST004772) | rs10865141 | -4.67993572727904 | 2.38283902023557 | 0.0495281504967197 |
| Other egg | Achilles tendon injury (ebi-a-GCST90018787) | rs145121823 | 6.53869962134098 | 2.74653267676796 | 0.0172792780712993 |
| Other egg | Achilles tendon injury (ebi-a-GCST90018787) | rs78886200 | 6.68032809162214 | 2.65799872807423 | 0.0119610140753767 |
| Other egg | Achilles tendon injury (ebi-a-GCST90018787) | All - Inverse variance weighted | 1.2760288896525 | 0.634999981548352 | 0.0444847308610052 |
| Other egg | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | rs10865141 | -0.0910120232437588 | 0.0335094347837326 | 0.0066073545398761 |
| Other egg | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | rs76351643 | -0.0640325135084777 | 0.0311329071175703 | 0.0397105680160551 |
| Other egg | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | All - MR Egger | 0.060567566249527 | 0.0216193651542921 | 0.0149854166939893 |
| Other egg | Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) | rs142712099 | 97.4468408454807 | 41.5236635807551 | 0.0189365084726962 |
| Other egg | Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) | All - Inverse variance weighted | 14.082886752713 | 5.90175976484208 | 0.0170226462693312 |
| Other egg | Cervical disc disorders (finn-b-M13_CERVICDISC) | rs116216151 | 13.0755199807575 | 4.50995196065986 | 0.0037404546450877 |
| Other egg | Cervical disc disorders (finn-b-M13_CERVICDISC) | rs72827495 | 4.60775550163879 | 2.33314178691525 | 0.0482778537449289 |
| Other egg | Cervical disc disorders (finn-b-M13_CERVICDISC) | All - Inverse variance weighted | 1.54884643313117 | 0.668850854865058 | 0.0205755931675302 |
| Other egg | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | rs148292197 | 227.765165537512 | 104.696956857218 | 0.029594858947272 |
| Other egg | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | rs191530496 | 27.5155567590465 | 9.87160479263463 | 0.0053142060805141 |
| Other egg | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | rs80253693 | 31.639704282892 | 15.0182811815573 | 0.0351395997887086 |
| Other egg | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | All - Inverse variance weighted | 8.04743582689457 | 3.86543950966707 | 0.0373521410371049 |
| Other egg | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | All - Inverse variance weighted | -3.86349845493783 | 1.87660438377836 | 0.0395161926867261 |
| Other egg | Pyogenic arthritis (finn-b-M13_PYOGARTH) | rs142044201 | 26.6557076893264 | 12.3422141143609 | 0.030794471068849 |
| Other egg | Pyogenic arthritis (finn-b-M13_PYOGARTH) | rs80253693 | -15.6917199805716 | 6.30827405979302 | 0.0128650860175292 |
| Other egg | Pyogenic arthritis (finn-b-M13_PYOGARTH) | All - MR Egger | -6.49551110388033 | 3.0253119996812 | 0.0449081431575956 |
| Other egg | Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) | rs76351643 | 36.5194708403205 | 14.5390814235141 | 0.0120112316834765 |
| Other egg | Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) | All - MR Egger | -13.4348699027504 | 5.92027299297432 | 0.0350870761637134 |
| Other egg | Spondylosis (finn-b-M13_SPONDYLOSIS) | rs191530496 | -4.25749821040299 | 1.51210893618847 | 0.0048685812504947 |
| Other egg | Spondylosis (finn-b-M13_SPONDYLOSIS) | All - MR Egger | -2.56132330423231 | 1.13327259228598 | 0.0357501443030455 |
| Other egg | Dislocation, sprain and strain of joints and ligaments at ankle and foot level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ANKLE_FOOT_LEVEL) | rs185735656 | -7.0569080026749 | 3.04456360562725 | 0.0204562916466696 |
| Other egg | Dislocation, sprain and strain of joints and ligaments at ankle and foot level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ANKLE_FOOT_LEVEL) | rs41286043 | -25.5650996418928 | 12.3746828834561 | 0.0388360739027811 |
| Other egg | Fracture of rib(s), sternum and thoracic spine (finn-b-ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE) | All - Inverse variance weighted | -1.80419910634936 | 0.813352422604039 | 0.0265394590457452 |
| Other egg | Fracture of skull and facial bones (finn-b-ST19_FRACT_SKULL_FACIAL_BONES) | rs142044201 | 20.8755153726386 | 7.09660605817613 | 0.0032650074898884 |
| Other egg | Fracture of skull and facial bones (finn-b-ST19_FRACT_SKULL_FACIAL_BONES) | rs142712099 | -18.0088904649131 | 6.36706728638188 | 0.0046774947995808 |
| Other egg | Fracture of skull and facial bones (finn-b-ST19_FRACT_SKULL_FACIAL_BONES) | rs77495543 | -12.6503027998011 | 5.11395219566426 | 0.0133727842913177 |
| Other egg | Fracture of skull and facial bones (finn-b-ST19_FRACT_SKULL_FACIAL_BONES) | All - MR Egger | -4.31936571295234 | 2.02359114082931 | 0.0460468965296079 |
| Other egg | Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) | rs76351643 | 34.1729550959568 | 14.2654182970002 | 0.0165972522554075 |
| Other egg | Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) | All - MR Egger | -13.7367479952714 | 5.72078076600343 | 0.0267381461553773 |
| Other egg | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | rs10865141 | 44.6806976392973 | 20.5580189199081 | 0.0297505931211433 |
| Other egg | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | All - MR Egger | -21.9653312220322 | 8.94366940154798 | 0.0238489032928742 |
| Other egg | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs12491093 | 50.8655126498003 | 21.9510597891336 | 0.0204915574091991 |
| Other egg | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs149247939 | 40.1940770155765 | 16.0519030174222 | 0.0122795615574593 |
| Other egg | Shoulder region (finn-b-Z21_SHOUL_REGION) | All - Inverse variance weighted | 14.922958609734 | 4.42050053393587 | 0.0007358730847181 |
| Other egg | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | rs76351643 | 11.1037357928079 | 4.43101360163965 | 0.0122135573769637 |
| Other egg | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | All - MR Egger | 6.89263897930087 | 2.44786850102133 | 0.0130379870273224 |
| Other egg | Bone morphogenetic protein 6 (prot-a-256) | rs116216151 | 8.67915199540319 | 4.03557182850156 | 0.0315028679006265 |
| Other egg | Bone morphogenetic protein 6 (prot-a-256) | rs78886200 | 8.34905121947242 | 3.95710240089578 | 0.0348678223393075 |
| Other egg | Bone morphogenetic protein 6 (prot-a-256) | All - Inverse variance weighted | 2.12863366497584 | 1.01930020047588 | 0.0367682117383965 |
| Other egg | Bone morphogenetic protein 7 (prot-a-257) | All - MR Egger | -5.74106363198139 | 2.44804674031932 | 0.0331888328589252 |
| Other egg | Bone proteoglycan II (prot-c-2666_53_2) | rs76351643 | -15.4357648593255 | 7.1561160797466 | 0.0310054197309075 |
| Other egg | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | rs185735656 | 0.131477797114933 | 0.0527041789023787 | 0.0126086027083446 |
| Other egg | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | All - Inverse variance weighted | 0.0231713375235427 | 0.011426704565195 | 0.0425782875458175 |
| Other egg | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | rs55892269 | 0.335225251926497 | 0.158434857891617 | 0.0343571064019134 |
| Other egg | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | rs72827495 | 0.312861809900822 | 0.154334801855872 | 0.0426457390996049 |
| Other egg | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | All - Inverse variance weighted | 0.0789400730557704 | 0.0401145274806516 | 0.0490832904319719 |
| Other egg | Fractured bone site(s): Leg (ukb-b-3798) | rs10865141 | 0.0632351600627489 | 0.0307702250225512 | 0.0398716360460759 |
| Other egg | Other disorders of synovium, tendon, and bursa (ukb-e-727_CSA) | All - Inverse variance weighted | 11.8532013561383 | 5.77739459879288 | 0.0402035254815132 |