ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Stewed fruit | Osteoarthritis (self-reported) (ebi-a-GCST005811) | rs148674336 | -4.11762536873156 | 1.47036276162382 | 0.0051037007210548 |
| Stewed fruit | Osteoarthritis (self-reported) (ebi-a-GCST005811) | All - Inverse variance weighted | -1.00005061057203 | 0.483476801310116 | 0.0385971406740659 |
| Stewed fruit | Osteoprotegerin levels (ebi-a-GCST90010243) | rs117969658 | 10.6525097152892 | 5.21093965951773 | 0.0409279783527224 |
| Stewed fruit | Heel bone mineral density T score (ebi-a-GCST90025982) | rs77446681 | -0.517648234932679 | 0.149060532616806 | 0.0005151772478028 |
| Stewed fruit | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | rs77446681 | 36.0669647864315 | 13.0130740309076 | 0.0055782473127477 |
| Stewed fruit | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | All - Inverse variance weighted | 7.1707749045863 | 3.07953040360015 | 0.0198840475002 |
| Stewed fruit | Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) | rs2519958 | -27.6697350137438 | 13.9562259937743 | 0.047411155315072 |
| Stewed fruit | Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) | All - MR Egger | 20.6392450893845 | 8.27407786006775 | 0.0413267161272531 |
| Stewed fruit | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | rs148674336 | 3.21849978929625 | 1.63997752493328 | 0.0497011874653166 |
| Stewed fruit | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | All - MR Egger | 5.35656548698584 | 2.07589963989298 | 0.0364532626937634 |
| Stewed fruit | Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) | rs2519958 | -3.84099611046049 | 1.09829430646659 | 0.0004701029866695 |
| Stewed fruit | Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) | All - MR Egger | 2.27706511351308 | 0.640760303091168 | 0.0092976336005698 |
| Stewed fruit | Shoulder lesions (finn-b-M13_SHOULDER) | rs2519958 | -2.43930558673794 | 1.12256600384706 | 0.0297823515015095 |
| Stewed fruit | Shoulder lesions (finn-b-M13_SHOULDER) | All - MR Egger | 1.70741608344905 | 0.658159374741051 | 0.0357240821924383 |
| Stewed fruit | Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) | All - MR Egger | 3.8885382028238 | 1.48560943637059 | 0.0345360211277121 |
| Stewed fruit | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | rs112872798 | 53.192479431304 | 21.4449075770027 | 0.0131225960537358 |
| Stewed fruit | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | rs148674336 | -9.74680432645035 | 3.55562579013906 | 0.0061208793131091 |
| Stewed fruit | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | All - Inverse variance weighted | -6.24687580042801 | 2.91676927371928 | 0.0322167736450817 |
| Stewed fruit | Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) | rs150680000 | -2.47130737158809 | 1.13255236687823 | 0.0291044432368178 |
| Stewed fruit | Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) | rs2519958 | 4.06550931122991 | 2.03275465561495 | 0.0455002638963584 |
| Stewed fruit | Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) | All - MR Egger | -3.41882600668614 | 1.20404549012737 | 0.0250643837354074 |
| Stewed fruit | Injury of muscle and tendon at forearm level (finn-b-ST19_INJURY_MUSCLE_TENDON_FOREA_LEVEL) | All - Inverse variance weighted | -5.38250431920362 | 2.31025973460143 | 0.0198153237029796 |
| Stewed fruit | Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) | rs146707334 | -5.94955605620076 | 2.95841311229787 | 0.044318770317189 |
| Stewed fruit | Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) | All - Inverse variance weighted | -1.63827043554477 | 0.816771780182179 | 0.0448789498997785 |
| Stewed fruit | Superficial injury of neck (finn-b-ST19_SUPERF_INJURY_NECK) | rs151156530 | -16.7268525205836 | 8.50426115845731 | 0.0491971642940208 |
| Stewed fruit | Superficial injury of neck (finn-b-ST19_SUPERF_INJURY_NECK) | All - Inverse variance weighted | -4.76360204988459 | 2.36306687004288 | 0.0438150569230289 |
| Stewed fruit | Bone morphogenetic protein 7 (prot-a-257) | All - Inverse variance weighted | -1.66760653078207 | 0.807098007089368 | 0.0388118642695818 |
| Stewed fruit | Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) | All - Inverse variance weighted | -0.0199675982600432 | 0.0080776413836184 | 0.0134374929097457 |
| Stewed fruit | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | rs148674336 | -0.0391684225312544 | 0.0194721871049305 | 0.0442720299647557 |
| Stewed fruit | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | All - Inverse variance weighted | -0.0146944244984849 | 0.0067556023783819 | 0.0296191439290484 |
| Stewed fruit | Operation code: elbow surgery (ukb-b-10324) | rs2519958 | -0.0319765656761791 | 0.0137063488692423 | 0.0196494711672467 |
| Stewed fruit | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | rs148674336 | -0.161781149037786 | 0.0792577960387695 | 0.0412307815325803 |
| Stewed fruit | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | All - Inverse variance weighted | -0.0551320458641466 | 0.0262101001305469 | 0.0354250830709226 |
| Stewed fruit | Non-cancer illness code, self-reported: other joint disorder (ukb-b-5316) | rs2519958 | 0.0273457078537145 | 0.0139499760316988 | 0.0499643381953487 |
| Stewed fruit | Non-cancer illness code, self-reported: spine arthritis/spondylitis (ukb-b-5389) | rs2519958 | -0.0394782798648066 | 0.0164835164835165 | 0.0166196561052481 |
| Stewed fruit | Diagnoses - main ICD10: M13 Other arthritis (ukb-d-M13) | All - Inverse variance weighted | 0.00975138819134 | 0.00497395637798 | 0.0499386289631919 |
| Stewed fruit | Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) | All - Inverse variance weighted | 0.0119960968563839 | 0.0051254023159266 | 0.019257005306112 |
| Stewed fruit | Other arthritis (FG) (ukb-d-RHEU_ARTHRITIS_OTH) | All - Inverse variance weighted | 0.00975138819134 | 0.00497395637798 | 0.0499386289631919 |
| Stewed fruit | Neck/shoulder pain for 3+ months (ukb-e-3404_CSA) | rs2519958 | 19.6175994077706 | 8.60431672137912 | 0.0226093615681349 |
| Stewed fruit | Neck/shoulder pain for 3+ months (ukb-e-3404_CSA) | All - Inverse variance weighted | 7.88339797271515 | 3.38842354597063 | 0.0199882665136539 |
| Stewed fruit | Osteoarthrosis (ukb-e-740_CSA) | rs112872798 | -16.2034791045811 | 5.93051691533915 | 0.0062909048194046 |
| Stewed fruit | Osteoarthrosis (ukb-e-740_CSA) | rs2519958 | 19.7450258190181 | 9.19290538285569 | 0.0317252932162979 |
| Stewed fruit | Osteoarthrosis (ukb-e-740_CSA) | All - MR Egger | -27.2182615903179 | 8.03727374955237 | 0.0428851705084175 |
| Stewed fruit | Pain in joint (ukb-e-745_CSA) | All - Inverse variance weighted | 11.4888173084952 | 4.69856755852839 | 0.0144782095347736 |