ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Other grain | Osteoporosis (bbj-a-137) | rs75760731 | -6.3761462908032 | 2.64125764476694 | 0.0157759976814212 |
| Other grain | Osteoporosis (bbj-a-137) | rs79962891 | -12.4570735004423 | 5.28127192482504 | 0.0183377890424639 |
| Other grain | Osteoporosis (bbj-a-137) | All - MR Egger | -2.34612187155104 | 1.04553448778137 | 0.0376501145788767 |
| Other grain | Rheumatoid Arthritis (bbj-a-74) | rs7173652 | 12.453505992561 | 5.22386003581761 | 0.017127173284463 |
| Other grain | Rheumatoid Arthritis (bbj-a-74) | rs75760731 | -9.43165697141655 | 3.18076607182857 | 0.0030247093235769 |
| Other grain | Rheumatoid Arthritis (bbj-a-74) | All - Inverse variance weighted | 1.48215006622356 | 0.619850635257575 | 0.0167961159545047 |
| Other grain | Rheumatoid arthritis (ebi-a-GCST002318) | rs75760731 | -9.45283492733653 | 3.04650326154097 | 0.0019166840049656 |
| Other grain | Rheumatoid arthritis (ebi-a-GCST002318) | All - Inverse variance weighted | 1.5204780177371 | 0.62953554006852 | 0.0157249406006438 |
| Other grain | Frozen shoulder (ebi-a-GCST90000512) | rs117647133 | -8.10954841550436 | 3.22248986622117 | 0.0118510966211941 |
| Other grain | Frozen shoulder (ebi-a-GCST90000512) | rs139141855 | -8.88961556638676 | 4.10561541362536 | 0.0303698167594442 |
| Other grain | Frozen shoulder (ebi-a-GCST90000512) | rs1917600 | 8.36450770948128 | 4.21378196352395 | 0.0471404976213378 |
| Other grain | Frozen shoulder (ebi-a-GCST90000512) | All - MR Egger | -2.56524942662804 | 1.04279456711879 | 0.0172552250138259 |
| Other grain | Osteoprotegerin levels (ebi-a-GCST90010243) | rs10093198 | 24.4136905743476 | 11.2135150151331 | 0.0294681379303711 |
| Other grain | Osteoprotegerin levels (ebi-a-GCST90010243) | rs72732838 | 21.8252600501219 | 10.8251570599746 | 0.0437831376273871 |
| Other grain | Osteoprotegerin levels (ebi-a-GCST90010243) | rs73173015 | -22.3784188649229 | 9.97451229816433 | 0.0248607120735662 |
| Other grain | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs76400165 | 5.27873950450917 | 2.20545247227117 | 0.0166887079788987 |
| Other grain | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | All - Inverse variance weighted | 0.644372369791905 | 0.271963901792319 | 0.0178203208189807 |
| Other grain | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs76400165 | 5.34844630853753 | 2.25819106776918 | 0.0178620745905062 |
| Other grain | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | All - Inverse variance weighted | 0.642128627213649 | 0.272059408484761 | 0.0182625491639799 |
| Other grain | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | rs139680449 | 65.5302922512165 | 27.9502575339347 | 0.0190509408210057 |
| Other grain | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | rs145490928 | 44.4344505227149 | 22.3241274569074 | 0.0465443890354352 |
| Other grain | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | rs7145793 | 109.194034586705 | 48.9515574594109 | 0.02570399304815 |
| Other grain | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | All - Inverse variance weighted | 4.79935466692357 | 2.34075927540229 | 0.0403311682233754 |
| Other grain | Heel bone mineral density T score (ebi-a-GCST90025982) | rs7145793 | -1.23299090380242 | 0.551484081654239 | 0.0253669196288078 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | rs10093198 | 128.193744307645 | 34.883514431627 | 0.0002379341199795 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | rs117647133 | -59.4622945724387 | 23.8354248416799 | 0.012606276387909 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | rs138274973 | -56.0300374851017 | 23.6952776182448 | 0.0180491753054438 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | rs2212392 | -84.1027563163712 | 40.0617677752433 | 0.0357880726744896 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | rs6573775 | 132.566360269898 | 37.7880003476048 | 0.0004512171844793 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | rs76400165 | 171.914744320674 | 82.9831513982027 | 0.0382950584178882 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | rs80228232 | 46.6667439326858 | 23.7824807028117 | 0.0497354835744323 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | All - MR Egger | -20.1651993123778 | 7.00028230035392 | 0.0053042949510387 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | rs10093198 | 127.584868419384 | 34.883514431627 | 0.0002547324148157 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | rs117647133 | -59.5399976689071 | 23.8613258738361 | 0.0125868054047526 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | rs138274973 | -56.1226695320847 | 23.7817341954289 | 0.0182795407402664 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | rs2212392 | -84.1541011004471 | 40.1387849513572 | 0.0360309316392378 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | rs6573775 | 132.846686681972 | 37.8160329888122 | 0.0004431232172164 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | rs76400165 | 171.890822974061 | 82.9911251804068 | 0.0383405547780377 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | rs80228232 | 46.7478732528221 | 23.7998655571266 | 0.0495060391281508 |
| Other grain | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | All - MR Egger | -20.0650497855852 | 7.01006649036674 | 0.0055849644101739 |
| Other grain | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | rs115036096 | 154.821199950894 | 72.6205299987723 | 0.0330133788779604 |
| Other grain | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | rs117238119 | 33.0058738183654 | 15.1095828246739 | 0.0289304334909303 |
| Other grain | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | All - MR Egger | -9.20674021704481 | 4.53495243617376 | 0.0462530658713032 |
| Other grain | Other bursitis of hip (finn-b-M13_BURSITISHIPOTH) | rs117447166 | 53.2206317162024 | 21.6348215970765 | 0.0138955436780824 |
| Other grain | Other bursitis of hip (finn-b-M13_BURSITISHIPOTH) | rs140689308 | 87.3913444780463 | 44.2657574260382 | 0.0483541630586204 |
| Other grain | Other bursitis of hip (finn-b-M13_BURSITISHIPOTH) | rs145490928 | 41.2568749170586 | 20.1934561111193 | 0.0410443791966158 |
| Other grain | Other bursitis of hip (finn-b-M13_BURSITISHIPOTH) | rs149206520 | -55.1508291615707 | 24.4988187391275 | 0.0243752286566257 |
| Other grain | Other bursitis of hip (finn-b-M13_BURSITISHIPOTH) | rs79411716 | 99.5961473168814 | 37.4010471578421 | 0.0077464900400669 |
| Other grain | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | rs144535592 | -16.9264670707441 | 7.02300798485473 | 0.0159461847101246 |
| Other grain | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | rs7145793 | 97.2023903961077 | 42.6913110159183 | 0.0227942345889143 |
| Other grain | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | rs7173652 | -43.0637828902053 | 19.1486430637829 | 0.0245175313742342 |
| Other grain | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | rs76934814 | -60.3537120203411 | 26.0206269323644 | 0.0203702976889012 |
| Other grain | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | All - Inverse variance weighted | -3.82052879529577 | 1.83945834108266 | 0.0378028727930343 |
| Other grain | Loose body in joint (finn-b-M13_LOOSEJOINT) | rs115036096 | 192.558620810607 | 73.1729774285764 | 0.0084995429294051 |
| Other grain | Loose body in joint (finn-b-M13_LOOSEJOINT) | rs138677842 | 98.4108659036181 | 40.5489814292299 | 0.0152258206950964 |
| Other grain | Loose body in joint (finn-b-M13_LOOSEJOINT) | rs1917600 | -54.3236118964336 | 19.4579951946367 | 0.005240924272722 |
| Other grain | Loose body in joint (finn-b-M13_LOOSEJOINT) | rs60219262 | -64.9914140625717 | 31.6348175832652 | 0.0399344105510596 |
| Other grain | Loose body in joint (finn-b-M13_LOOSEJOINT) | rs74697960 | 45.9260835530966 | 20.9300734908535 | 0.0282165156499156 |
| Other grain | Loose body in joint (finn-b-M13_LOOSEJOINT) | rs75306820 | 105.549687660319 | 35.5735280803935 | 0.0030063766535881 |
| Other grain | Loose body in joint (finn-b-M13_LOOSEJOINT) | All - Inverse variance weighted | -5.17587850916428 | 2.28697932002743 | 0.0236237158534001 |
| Other grain | Osteomalacia (finn-b-M13_OSTEOMALACIA) | rs138677842 | 135.268093685249 | 64.4398399234941 | 0.0358047689796311 |
| Other grain | Osteomalacia (finn-b-M13_OSTEOMALACIA) | rs139141855 | 52.421029516367 | 26.2510920053276 | 0.0458351205302133 |
| Other grain | Osteomalacia (finn-b-M13_OSTEOMALACIA) | rs7587553 | 147.436699247717 | 71.502599932098 | 0.0392099487348953 |
| Other grain | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs10093198 | 26.3085123386162 | 10.3001504430841 | 0.0106436017728471 |
| Other grain | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs138677842 | 51.6113190803786 | 19.3332443062131 | 0.0075949960222266 |
| Other grain | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs149206520 | -20.2979360219996 | 10.3008986698471 | 0.0487809261157252 |
| Other grain | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs316363 | 22.177989454366 | 10.8394923458214 | 0.040752848004841 |
| Other grain | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs34682847 | -48.3734694902792 | 24.4790215698543 | 0.0481412553529094 |
| Other grain | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs76934814 | -33.2423100358827 | 15.7598188561155 | 0.0349180154189309 |
| Other grain | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs78740020 | -42.0179810872502 | 20.2093135199764 | 0.037604534630891 |
| Other grain | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | rs138081174 | -13.8760167770914 | 6.34960320368303 | 0.0288642160874933 |
| Other grain | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | rs144535592 | -14.2597596909877 | 7.07389934706382 | 0.0438180338094566 |
| Other grain | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | rs77691495 | 98.6480338634386 | 44.544663343619 | 0.0267884228114013 |
| Other grain | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | All - Inverse variance weighted | -3.80329707142996 | 1.84692294153111 | 0.0394692067238883 |
| Other grain | Congenital malformations of eye, ear, face and neck (finn-b-Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK) | rs6573775 | 38.8252080722794 | 13.3996024971477 | 0.0037616228201506 |
| Other grain | Congenital malformations of eye, ear, face and neck (finn-b-Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK) | rs72732838 | -19.7260462082461 | 9.66047581448041 | 0.0411581588448199 |
| Other grain | Congenital malformations of eye, ear, face and neck (finn-b-Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK) | All - Inverse variance weighted | -2.82324479917659 | 1.32830121636911 | 0.0335486439792941 |
| Other grain | Congenital malformations of eye, ear, face and neck (finn-b-Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK) | All - MR Egger | -5.8832474991937 | 2.35351316343496 | 0.0148453377173165 |
| Other grain | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | rs60219262 | 185.619243519224 | 65.4849906794369 | 0.0045892988861973 |
| Other grain | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | rs74504207 | 181.697951440194 | 81.796457432642 | 0.0263277688874167 |
| Other grain | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | rs9910640 | -46.4602370519983 | 22.597581700411 | 0.0397841837075266 |
| Other grain | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | rs117647133 | -38.4630327518552 | 19.5293782457231 | 0.0488961590277907 |
| Other grain | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | All - Inverse variance weighted | -6.2395620203572 | 3.10804015151783 | 0.0446905843151633 |
| Other grain | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | rs316363 | -47.0727826168919 | 23.4532238479921 | 0.0447398467601916 |
| Other grain | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | rs75760731 | 43.2858413146623 | 17.2274526041419 | 0.0119842296765714 |
| Other grain | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | All - MR Egger | 9.69123881893742 | 4.25756208730968 | 0.0259850711359672 |
| Other grain | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | rs116701056 | -5.27729184828079 | 2.61524329953604 | 0.0436019800117875 |
| Other grain | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | rs148766918 | 16.7668627952588 | 7.69591540888548 | 0.0293561651534254 |
| Other grain | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | rs7173652 | -9.34012949442072 | 4.46342471414795 | 0.0363855383762003 |
| Other grain | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | rs75664696 | 5.94583043966024 | 2.91148031411934 | 0.0411315145601689 |
| Other grain | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | rs78626557 | 6.52109207998485 | 3.16042968855697 | 0.0390788015226752 |
| Other grain | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | All - MR Egger | 1.95915872227367 | 0.757117942824533 | 0.0118043734974741 |
| Other grain | Fracture of shoulder and upper arm (finn-b-ST19_FRACT_SHOUL_UPPER_ARM) | All - Inverse variance weighted | 1.21200050879126 | 0.560620743994388 | 0.0306266383047887 |
| Other grain | Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) | rs117238119 | 4.67860178835079 | 1.62984078692548 | 0.0040970883425799 |
| Other grain | Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) | rs76629987 | 13.9374739605852 | 6.66609019660249 | 0.0365458269136055 |
| Other grain | Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) | rs80299147 | 3.63508098098196 | 1.70486277814248 | 0.0329917308194629 |
| Other grain | Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) | All - MR Egger | 1.08441480041171 | 0.490863466066678 | 0.0305328598618874 |
| Other grain | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | rs316363 | 66.0072411135568 | 24.2017309920769 | 0.0063840080430744 |
| Other grain | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | All - MR Egger | -10.9642923130176 | 4.38487877628968 | 0.014818350643744 |
| Other grain | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs117447166 | 19.1985450968506 | 6.5825217177465 | 0.003538757717726 |
| Other grain | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs140689308 | -32.3591210915231 | 13.7471970811638 | 0.0185790845227849 |
| Other grain | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs145490928 | 15.9247408543329 | 6.34777864610212 | 0.0121172643901137 |
| Other grain | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs72732838 | 12.3931477222012 | 5.994026571458 | 0.0386792475907465 |
| Other grain | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs74504207 | 42.1842791732793 | 15.5876612123534 | 0.0068045548559622 |
| Other grain | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs75664696 | 14.0125006677707 | 5.74282814252898 | 0.0146872619106967 |
| Other grain | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs77603410 | -20.1482067179974 | 7.35248031704859 | 0.0061377922463953 |
| Other grain | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | All - Inverse variance weighted | 2.23718585421628 | 0.9323800915893 | 0.0164203741888189 |
| Other grain | Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) | rs144141363 | 9.68339332049887 | 4.39964007700678 | 0.0277394753005459 |
| Other grain | Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) | rs76934814 | -28.6234418842575 | 11.8255060820112 | 0.0154998843803487 |
| Other grain | Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) | rs79411716 | 23.8916388198924 | 11.06127481639 | 0.0307776724185904 |
| Other grain | Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) | All - MR Egger | 3.08851064468969 | 1.45496136719705 | 0.0374190061541018 |
| Other grain | Ankle and foot (finn-b-Z21_ANKLE_FOOT) | rs148766918 | 127.712756885819 | 65.0422102839601 | 0.0495838623666108 |
| Other grain | Ankle and foot (finn-b-Z21_ANKLE_FOOT) | rs74697960 | 71.5300841306876 | 35.0354534469262 | 0.0411864017538273 |
| Other grain | Ankle and foot (finn-b-Z21_ANKLE_FOOT) | rs77603410 | 101.199056954 | 35.7451075872776 | 0.0046383821788533 |
| Other grain | Ankle and foot (finn-b-Z21_ANKLE_FOOT) | All - Inverse variance weighted | -7.46997470893491 | 3.79038788395713 | 0.0487504317946875 |
| Other grain | Rheumatoid arthritis (ieu-a-831) | rs7173652 | 19.9946824631492 | 7.5648987463838 | 0.0082154021310112 |
| Other grain | Rheumatoid arthritis (ieu-a-831) | All - Inverse variance weighted | 2.23257837603196 | 1.06657698563146 | 0.0363296792899903 |
| Other grain | Rheumatoid arthritis (ieu-a-833) | rs7173652 | 11.2472792395647 | 5.15415346466455 | 0.029096413479782 |
| Other grain | Rheumatoid arthritis (ieu-a-833) | rs80228232 | 4.45985257643541 | 2.04700285111611 | 0.029352238148413 |
| Other grain | Femoral neck bone mineral density (ieu-a-980) | rs72732838 | -4.12928696488036 | 1.86048268049023 | 0.0264547122975583 |
| Other grain | Femoral neck bone mineral density (ieu-a-980) | rs80164614 | 6.0415888864771 | 2.13205990883438 | 0.0046014482392942 |
| Other grain | Femoral neck bone mineral density (ieu-a-980) | All - Inverse variance weighted | 0.569573826369998 | 0.269951369420175 | 0.03486587497488 |
| Other grain | Bone sialoprotein 2 (prot-a-1396) | rs116701056 | 13.6905353935444 | 6.95057950749177 | 0.0488731104972685 |
| Other grain | Bone sialoprotein 2 (prot-a-1396) | rs76934814 | -15.5341412591305 | 7.61285760495889 | 0.0412991745921584 |
| Other grain | Bone sialoprotein 2 (prot-a-1396) | All - Inverse variance weighted | -1.83273356695504 | 0.888439679819809 | 0.0391251945427274 |
| Other grain | Fractured/broken bones in last 5 years (ukb-a-308) | rs138274973 | 0.40402702385584 | 0.203610797191396 | 0.0472212467277185 |
| Other grain | Fractured/broken bones in last 5 years (ukb-a-308) | rs76400165 | 0.462409995933371 | 0.221392062897194 | 0.0367394589867314 |
| Other grain | Fractured/broken bones in last 5 years (ukb-a-308) | All - Inverse variance weighted | 0.054893380576738 | 0.0254182471840839 | 0.0308032401006714 |
| Other grain | Fractured bone site(s): Ankle (ukb-a-438) | rs10788043 | 0.196125157127027 | 0.0850400182065292 | 0.0210956065963048 |
| Other grain | Fractured bone site(s): Ankle (ukb-a-438) | rs145490928 | -0.18386366652413 | 0.0885585160500745 | 0.037877048794869 |
| Other grain | Fractured bone site(s): Ankle (ukb-a-438) | rs77603410 | -0.240465641015751 | 0.0879110759692015 | 0.00623181161065 |
| Other grain | Fractured bone site(s): Ankle (ukb-a-438) | All - MR Egger | -0.0377074042514176 | 0.0184952270956793 | 0.0453637735650687 |
| Other grain | Fractured bone site(s): Other bones (ukb-a-441) | All - Inverse variance weighted | 0.0388332549190577 | 0.019137738041858 | 0.0424434732781497 |
| Other grain | Fractured bone site(s): Other bones (ukb-a-441) | All - MR Egger | 0.0761977310463615 | 0.0342020464740533 | 0.0292008199919477 |
| Other grain | Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) | rs138081174 | 0.0942129380170099 | 0.0388778919144937 | 0.0153800643121364 |
| Other grain | Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) | rs144141363 | -0.0961596007365866 | 0.0404030823637733 | 0.0173123302394096 |
| Other grain | Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) | rs74504207 | 0.0842402269286196 | 0.040256297998869 | 0.0363851035340998 |
| Other grain | Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) | rs75885888 | 0.0797402782563238 | 0.0383692539831525 | 0.0376878357885612 |
| Other grain | Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) | All - Inverse variance weighted | 0.0090560170389013 | 0.0046087955134151 | 0.0494209216175155 |
| Other grain | Operative procedures - secondary OPCS: Z81.4 Shoulder joint (ukb-b-11427) | All - Inverse variance weighted | -0.0544815107741291 | 0.0243144529581302 | 0.0250452047937423 |
| Other grain | Fractured/broken bones in last 5 years (ukb-b-13346) | rs138274973 | 0.458478611260352 | 0.171261216197022 | 0.0074268667084867 |
| Other grain | Fractured/broken bones in last 5 years (ukb-b-13346) | rs73100972 | -0.38270590993234 | 0.183325114989451 | 0.0368357049752513 |
| Other grain | Fractured/broken bones in last 5 years (ukb-b-13346) | rs76400165 | 0.427889898015326 | 0.189621325083127 | 0.0240362416733427 |
| Other grain | Fractured/broken bones in last 5 years (ukb-b-13346) | All - Inverse variance weighted | 0.0548230639768588 | 0.0238270173218895 | 0.0213985184344258 |
| Other grain | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | rs147403107 | -0.42686444893063 | 0.178243219520758 | 0.0166275030470175 |
| Other grain | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | rs78626557 | -0.392611413264064 | 0.159731038774792 | 0.0139731393234475 |
| Other grain | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | All - Inverse variance weighted | -0.052977228766146 | 0.022964598289963 | 0.0210599172750984 |
| Other grain | Fracture resulting from simple fall (ukb-b-15251) | rs10886080 | 2.26094295692666 | 0.94151144741948 | 0.0163325972421096 |
| Other grain | Fracture resulting from simple fall (ukb-b-15251) | rs138677842 | -1.50842814003679 | 0.57324275541809 | 0.0085035130369734 |
| Other grain | Fracture resulting from simple fall (ukb-b-15251) | rs80164614 | -2.01732146733232 | 0.964636422834817 | 0.0365032865176977 |
| Other grain | Fracture resulting from simple fall (ukb-b-15251) | All - MR Egger | -0.605787236025529 | 0.294148425521517 | 0.0469494803959279 |
| Other grain | Neck/shoulder pain for 3+ months (ukb-b-16118) | rs10093198 | -1.55401363374593 | 0.577655777090537 | 0.0071407703311393 |
| Other grain | Neck/shoulder pain for 3+ months (ukb-b-16118) | rs117238119 | 1.25963044159098 | 0.537338693698588 | 0.0190678410892072 |
| Other grain | Neck/shoulder pain for 3+ months (ukb-b-16118) | rs316363 | -1.41221120099357 | 0.606401676656003 | 0.0198676553151756 |
| Other grain | Neck/shoulder pain for 3+ months (ukb-b-16118) | rs62362585 | 1.72593718338399 | 0.631008668242711 | 0.0062341702056137 |
| Other grain | Neck/shoulder pain for 3+ months (ukb-b-16118) | rs75885888 | -1.30855917402307 | 0.59789466180332 | 0.0286250842195222 |
| Other grain | Neck/shoulder pain for 3+ months (ukb-b-16118) | rs76934814 | -1.287874342714 | 0.597040614444871 | 0.0309981302309476 |
| Other grain | Neck/shoulder pain for 3+ months (ukb-b-16118) | All - MR Egger | 0.262143951938272 | 0.126728673834228 | 0.0423383908466792 |
| Other grain | Fractured heel (ukb-b-18389) | rs149206520 | 0.0918147357546016 | 0.0463661984670197 | 0.0476801162007 |
| Other grain | Fractured heel (ukb-b-18389) | rs78740020 | -0.083737053772457 | 0.0424093569975622 | 0.0483255110582705 |
| Other grain | Fractured heel (ukb-b-18389) | rs79411716 | 0.0811093440074338 | 0.0406483979914583 | 0.0460005292780739 |
| Other grain | Fractured heel (ukb-b-18389) | rs9910640 | -0.098493313569951 | 0.0450437889227328 | 0.0287708213512773 |
| Other grain | Fractured heel (ukb-b-18389) | All - Inverse variance weighted | -0.0129343617410743 | 0.005157601848884 | 0.0121476887039101 |
| Other grain | Ankle spacing width (left) (ukb-b-2122) | rs117647133 | -2.05649015113252 | 0.973930611134854 | 0.0347262137181656 |
| Other grain | Ankle spacing width (left) (ukb-b-2122) | rs145330250 | -2.05610121927618 | 0.944148764595833 | 0.0294261337776142 |
| Other grain | Ankle spacing width (left) (ukb-b-2122) | rs73046496 | -2.42680725102136 | 0.935254544120165 | 0.009464339636561 |
| Other grain | Ankle spacing width (left) (ukb-b-2122) | rs73100972 | -2.04465389994099 | 0.915898049423234 | 0.0255883147241164 |
| Other grain | Ankle spacing width (left) (ukb-b-2122) | rs75885888 | -1.90835481839676 | 0.930869580714532 | 0.0403568649242245 |
| Other grain | Ankle spacing width (left) (ukb-b-2122) | All - MR Egger | -0.462277101237019 | 0.198144203976462 | 0.0225682337645845 |
| Other grain | Ankle spacing width (right) (ukb-b-8607) | rs148766918 | -1.89228383218214 | 0.916165686023706 | 0.038881533892593 |
| Other grain | Ankle spacing width (right) (ukb-b-8607) | rs62362585 | 2.47492401215805 | 0.982288265976209 | 0.0117505082280676 |
| Other grain | Ankle spacing width (right) (ukb-b-8607) | rs73046496 | -2.12190229224258 | 0.948675294175209 | 0.0253059359656991 |
| Other grain | Ankle spacing width (right) (ukb-b-8607) | rs73100972 | -3.03491314153605 | 0.926948353771411 | 0.001060025174981 |
| Other grain | Ankle spacing width (right) (ukb-b-8607) | rs75885888 | -2.30587403614243 | 0.942857652048903 | 0.0144602253198065 |
| Other grain | Ankle spacing width (right) (ukb-b-8607) | rs77084670 | -1.99518376095316 | 0.978030637332157 | 0.0413501973360661 |
| Other grain | Ankle spacing width (right) (ukb-b-8607) | All - MR Egger | -0.471839829033112 | 0.220497662855023 | 0.0359024071299292 |
| Other grain | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs10788043 | 0.246105057629195 | 0.124002628886701 | 0.0471805161782203 |
| Other grain | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs140689308 | 0.262787553683022 | 0.11826335763887 | 0.0262796640123123 |
| Other grain | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs150174335 | -0.248494280545307 | 0.111479508255103 | 0.0258100514157405 |
| Other grain | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs7173652 | 0.262102768976443 | 0.125108141617303 | 0.0361701311072722 |
| Other grain | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs928625 | 0.273751655510613 | 0.132131990856979 | 0.0382836752701857 |
| Other grain | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | All - MR Egger | -0.0621472863282998 | 0.026414672326781 | 0.0215351778625001 |
| Other grain | Rheumatoid arthritis (ukb-d-M13_RHEUMA) | rs77084670 | 0.119063228897434 | 0.0498534325159175 | 0.0169281113230649 |
| Other grain | Rheumatoid arthritis (ukb-d-M13_RHEUMA) | rs78740020 | 0.109992080868309 | 0.0448461204018571 | 0.0141806100120534 |
| Other grain | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | rs10093198 | -0.181741841697343 | 0.0789153890843775 | 0.021279056532161 |
| Other grain | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | rs117447166 | 0.278431518326404 | 0.0815517823135476 | 0.0006397701851348 |
| Other grain | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | rs141477622 | 0.17226004864093 | 0.0859638263548058 | 0.0450843420079573 |
| Other grain | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | rs141891455 | 0.176558819246353 | 0.0784866240074011 | 0.0244781454601334 |
| Other grain | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | rs34682847 | 0.169589839379256 | 0.0775669862031485 | 0.0287888220347472 |
| Other grain | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | rs78626557 | 0.183983548448197 | 0.0782395757231377 | 0.018695843037154 |
| Other grain | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | All - MR Egger | 0.0399383979480824 | 0.0189250098189481 | 0.0385095369842586 |
| Other grain | Ankle spacing width (left) (ukb-e-4100_EAS) | rs138677842 | -14.663628257208 | 6.46595358815193 | 0.023340091337473 |
| Other grain | Ankle spacing width (left) (ukb-e-4100_EAS) | All - Inverse variance weighted | -2.72274772481671 | 1.07114690555643 | 0.0110251887053465 |
| Other grain | Ankle spacing width (right) (ukb-e-4119_EAS) | rs138677842 | -14.6765515488565 | 6.58226321298877 | 0.0257665659338293 |
| Other grain | Ankle spacing width (right) (ukb-e-4119_EAS) | rs77084670 | -11.5299754144865 | 4.17764609468575 | 0.0057815246101082 |
| Other grain | Ankle spacing width (right) (ukb-e-4119_EAS) | All - Inverse variance weighted | -2.8087608893123 | 1.23277137530258 | 0.0227020520254885 |
| Other grain | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_EAS) | All - MR Egger | -4.8319002650112 | 2.24977348633108 | 0.0441717058693063 |