ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Berry | Osteoarthritis (self-reported) (ebi-a-GCST005811) | rs696217 | 2.75154224503651 | 0.687233511596019 | 6.23343289323382e-05 |
| Berry | Osteoarthritis (self-reported) (ebi-a-GCST005811) | rs7658609 | 1.24224475088464 | 0.603217082196329 | 0.0394591900834379 |
| Berry | Osteoarthritis (self-reported) (ebi-a-GCST005811) | All - Inverse variance weighted | 0.699465962436749 | 0.203745982835068 | 0.0005968772289588 |
| Berry | Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) | rs696217 | 2.92807865382603 | 0.954579240134059 | 0.0021592796049581 |
| Berry | Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) | All - Inverse variance weighted | 0.849939751183068 | 0.252345643198567 | 0.0007567248351323 |
| Berry | Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) | rs72791977 | 3.10575635876841 | 1.10219086002431 | 0.0048353515535781 |
| Berry | Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) | All - Inverse variance weighted | 1.134625060466 | 0.304644594054968 | 0.0001957631439136 |
| Berry | Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) | All - MR Egger | 1.50133362635012 | 0.678203869062663 | 0.0489020178560053 |
| Berry | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs696217 | 2.50845383729885 | 0.77122448486735 | 0.001143704849483 |
| Berry | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | All - Inverse variance weighted | 0.641617639557805 | 0.204309155106703 | 0.0016870272542244 |
| Berry | Neck circumference (ebi-a-GCST90017134) | rs12964409 | 8.62221672948979 | 3.16793342808297 | 0.0064943826692894 |
| Berry | Neck circumference (ebi-a-GCST90017134) | rs1498885 | -9.74088062341636 | 2.98800019123201 | 0.0011141221380492 |
| Berry | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | rs12964409 | 8.62221672948979 | 3.16793342808297 | 0.0064943826692894 |
| Berry | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | rs1498885 | -9.74088062341636 | 2.98800019123201 | 0.0011141221380492 |
| Berry | Pain in joint (finn-b-JOINTPAIN) | rs149701248 | 0.898990983254616 | 0.436077715757836 | 0.0392516980738843 |
| Berry | Pain in joint (finn-b-JOINTPAIN) | rs72665864 | -1.5983181334187 | 0.810510757997834 | 0.0486108855991463 |
| Berry | Pain in joint (finn-b-JOINTPAIN) | All - Inverse variance weighted | 0.375677177976358 | 0.186759358228688 | 0.0442666088051791 |
| Berry | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs113544454 | 9.47637139637618 | 4.20119464305302 | 0.0240933544074107 |
| Berry | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs696217 | 8.98916202226629 | 4.40066439299006 | 0.0410838360064331 |
| Berry | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | All - Inverse variance weighted | 2.54521709570987 | 1.26221951850082 | 0.0437517375246845 |
| Berry | Other specific joint derangements/joint disorders (finn-b-M13_JOINTOTH) | rs149701248 | 0.897872835265493 | 0.398060684127666 | 0.0240945663518027 |
| Berry | Other specific joint derangements/joint disorders (finn-b-M13_JOINTOTH) | All - Inverse variance weighted | 0.336061570836932 | 0.164870214722458 | 0.0415159316882895 |
| Berry | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | rs1498885 | 1.34659208618189 | 0.565728036206594 | 0.0172994081285744 |
| Berry | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | All - Inverse variance weighted | 0.307957383964012 | 0.138692250331613 | 0.0263891276919472 |
| Berry | Drug-induced osteoporosis with pathological fracture (finn-b-OSTPOPATFRACTURE) | All - Inverse variance weighted | -2.72851254315441 | 1.32895531627285 | 0.0400603713081463 |
| Berry | Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) | rs7658609 | 9.76946808424496 | 3.35635683457898 | 0.0036057874252848 |
| Berry | Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) | All - Inverse variance weighted | 2.35576077721897 | 1.05850377206178 | 0.0260438502754749 |
| Berry | Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) | rs7658609 | -1.7773711102294 | 0.813784950241706 | 0.0289563992820184 |
| Berry | Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) | All - Inverse variance weighted | -0.477668637529032 | 0.233463977371271 | 0.0407558060455831 |
| Berry | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | rs113544454 | 14.494271098214 | 6.10584258234361 | 0.0176043508179108 |
| Berry | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | rs149701248 | 12.0860616144268 | 4.96793151567196 | 0.0149819259705455 |
| Berry | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | All - MR Egger | 12.0255493656922 | 3.89913364765282 | 0.0103938518742476 |
| Berry | Lumbar spine bone mineral density (ieu-a-982) | All - MR Egger | -0.599661030706254 | 0.263310771461635 | 0.048770286476476 |
| Berry | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) | rs449233 | -0.127434527444196 | 0.0476596105570256 | 0.0074986556712961 |
| Berry | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) | rs78192709 | -0.123826426293851 | 0.0459810488087431 | 0.0070814754803686 |
| Berry | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) | All - Inverse variance weighted | -0.0492539517987018 | 0.0154991467344054 | 0.0014837187455482 |
| Berry | Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe (ukb-b-17501) | All - Inverse variance weighted | 0.007410505659781 | 0.0032232767917377 | 0.0215015515183581 |
| Berry | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | rs449233 | -0.104250118732614 | 0.0408706492977814 | 0.010749660670774 |
| Berry | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | rs78192709 | -0.0802933068233634 | 0.0399491176143605 | 0.0444428990972351 |
| Berry | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | All - Inverse variance weighted | -0.0293257015416264 | 0.0141744456392558 | 0.0385542071480426 |
| Berry | Ankle spacing width (ukb-b-4080) | rs1498885 | -0.215053146563401 | 0.103562493028 | 0.0378427088739512 |
| Berry | Ankle spacing width (ukb-b-4080) | rs6064351 | -0.47598941817481 | 0.0981166453511799 | 1.22679211638689e-06 |
| Berry | Ankle spacing width (ukb-b-4080) | All - Inverse variance weighted | -0.0890318262942214 | 0.0452859019018704 | 0.04929926576364 |
| Berry | Operation code: shoulder surgery (ukb-b-5935) | rs12964409 | -0.0329343137860718 | 0.0122384807102103 | 0.0071228386299881 |
| Berry | Operation code: shoulder surgery (ukb-b-5935) | rs1498885 | -0.0321595273382098 | 0.0115682220203662 | 0.0054360777842003 |
| Berry | Operation code: shoulder surgery (ukb-b-5935) | rs7658609 | -0.0244220507380746 | 0.0120671352340543 | 0.0429857661346564 |
| Berry | Operation code: shoulder surgery (ukb-b-5935) | All - Inverse variance weighted | -0.0131520472788547 | 0.0065536511505011 | 0.0447680348615361 |
| Berry | Impingement syndrome of shoulder (ukb-d-M13_IMPINGEMENT) | rs449233 | -0.0326146617816677 | 0.0106354230273424 | 0.0021650336688353 |
| Berry | Impingement syndrome of shoulder (ukb-d-M13_IMPINGEMENT) | All - MR Egger | -0.0212008190858286 | 0.0066822421104499 | 0.0088756584917371 |
| Berry | Shoulder lesions (ukb-d-M13_SHOULDER) | rs449233 | -0.0419840219824954 | 0.0153891207001832 | 0.0063688225531478 |
| Berry | Shoulder lesions (ukb-d-M13_SHOULDER) | rs696217 | -0.0322002516965366 | 0.0163334952276941 | 0.0486753477390424 |
| Berry | Shoulder lesions (ukb-d-M13_SHOULDER) | All - MR Egger | -0.0309152138974425 | 0.0101387340774317 | 0.0110629336105533 |
| Berry | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | rs449233 | -0.0419343239025714 | 0.0153901723319085 | 0.006435080196137 |
| Berry | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | rs696217 | -0.0322799466553609 | 0.0163346222271119 | 0.0481358296865943 |
| Berry | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | All - MR Egger | -0.0310991622418464 | 0.0101248412588614 | 0.0106300723265385 |
| Berry | Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) | rs149701248 | -0.0189196230499499 | 0.0078493429762415 | 0.0159374503636851 |
| Berry | Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) | rs72665864 | -0.0176136020505695 | 0.0082245500757157 | 0.0322266080824491 |
| Berry | Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) | All - MR Egger | -0.0134216804411046 | 0.0052772377930423 | 0.0273182737478581 |
| Berry | Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) | All - MR Egger | 0.0117270830086996 | 0.0047921705510459 | 0.0324101237761055 |