ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Other cereal (ukb-b-8917)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Other cereal (👉 📊) Ultradistal forearm bone mineral density (ebi-a-GCST90013422) Inverse variance weighted 13 0.912705472 0.405068241 0.024245653
Other cereal (👉 📊) Juvenile rheumatoid arthritis (ebi-a-GCST90018653) Inverse variance weighted 4 19.6226991 9.548116158 0.03986565
Other cereal (👉 📊) Rheumatoid arthritis (ebi-a-GCST90018910) Inverse variance weighted 14 -1.393880719 0.582400097 0.016695819
Other cereal (👉 📊) Heel bone mineral density (ebi-a-GCST90029004) Inverse variance weighted 14 -0.167719907 0.072923837 0.021452041
Other cereal (👉 📊) Sciatica (ebi-a-GCST90038692) Weighted median 13 -0.025284525 0.01065896 0.017685479
Other cereal (👉 📊) Sciatica (ebi-a-GCST90038692) Inverse variance weighted 13 -0.024015663 0.007898127 0.002360459
Other cereal (👉 📊) Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) Simple mode 14 -17.15435521 7.851148885 0.047799694
Other cereal (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) Simple mode 14 -17.72181488 7.8589114 0.042017939
Other cereal (👉 📊) Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) MR Egger 14 -25.16376042 8.822028274 0.014558368
Other cereal (👉 📊) Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) MR Egger 14 -25.36001254 8.829037944 0.014028681
Other cereal (👉 📊) Achilles tendinitis (finn-b-M13_ACHILLESTEND) Inverse variance weighted 14 -2.999492247 1.293970049 0.020446395
Other cereal (👉 📊) Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) Inverse variance weighted 14 10.62336619 5.395487673 0.04896052
Other cereal (👉 📊) Other bursitis of hip (finn-b-M13_BURSITISHIPOTH) Inverse variance weighted 14 -6.502417144 3.263963943 0.04635086
Other cereal (👉 📊) Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) MR Egger 14 9.423393648 3.407938964 0.017115688
Other cereal (👉 📊) Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) Inverse variance weighted 14 4.534566803 1.783865641 0.011022365
Other cereal (👉 📊) Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) MR Egger 14 11.55230095 3.681737357 0.008567946
Other cereal (👉 📊) Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) Weighted median 14 -3.788320224 1.888677197 0.044876941
Other cereal (👉 📊) Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) Inverse variance weighted 14 -2.864590554 1.458322529 0.049494707
Other cereal (👉 📊) Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) Weighted median 14 -9.633647737 4.812560179 0.045309269
Other cereal (👉 📊) Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) MR Egger 14 -21.3750901 9.740853363 0.048624921
Other cereal (👉 📊) Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) Inverse variance weighted 14 -1.103996543 0.516079273 0.032419511
Other cereal (👉 📊) Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) MR Egger 14 4.92583069 1.954149908 0.026874501
Other cereal (👉 📊) Heel bone mineral density (BMD) T-score automated (left) (ukb-a-361) Inverse variance weighted 13 -0.458914199 0.167900459 0.006271241
Other cereal (👉 📊) Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) Inverse variance weighted 13 -0.355928044 0.166875481 0.03293326
Other cereal (👉 📊) Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) MR Egger 13 -0.220964236 0.086810637 0.027219072
Other cereal (👉 📊) Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) Inverse variance weighted 13 -0.101823355 0.050661089 0.044442544
Other cereal (👉 📊) Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) Weighted median 13 -0.006210798 0.002881844 0.031150318
Other cereal (👉 📊) Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) Inverse variance weighted 13 -0.005486861 0.0021071 0.009214626
Other cereal (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) Inverse variance weighted 13 0.012856915 0.005276782 0.014829895
Other cereal (👉 📊) Heel bone mineral density (BMD) (left) (ukb-b-1096) Inverse variance weighted 14 -0.361821398 0.152736375 0.017839751
Other cereal (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) Inverse variance weighted 14 -0.363418787 0.155682252 0.019576757
Other cereal (👉 📊) Operative procedures - main OPCS: W87.9 Unspecified diagnostic endoscopic examination of knee joint (ukb-b-15942) Weighted median 3 -0.03319752 0.016115783 0.039404431
Other cereal (👉 📊) Operative procedures - main OPCS: W87.9 Unspecified diagnostic endoscopic examination of knee joint (ukb-b-15942) Inverse variance weighted 3 -0.032403293 0.013639941 0.017519576
Other cereal (👉 📊) Non-cancer illness code, self-reported: ankylosing spondylitis (ukb-b-18194) Inverse variance weighted 3 0.019746587 0.009185016 0.031565537
Other cereal (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) Inverse variance weighted 14 -0.367221643 0.146070026 0.011936673
Other cereal (👉 📊) Heel bone mineral density (BMD) (right) (ukb-b-4657) Inverse variance weighted 14 -0.380475971 0.140124084 0.006621998
Other cereal (👉 📊) Knee pain for 3+ months (ukb-b-8906) MR Egger 14 0.34663009 0.133850762 0.023672039
Other cereal (👉 📊) Heel bone mineral density (BMD) (left) (ukb-e-4105_AFR) Weighted median 6 -2.136130435 1.05837692 0.043559211
Other cereal (👉 📊) Heel bone mineral density (BMD) (left) (ukb-e-4105_AFR) Inverse variance weighted 6 -1.809329066 0.829985975 0.029261066
Other cereal (👉 📊) Ankle spacing width (right) (ukb-e-4119_AFR) Inverse variance weighted 6 1.580915358 0.615558123 0.010220948

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other cereal Ultradistal forearm bone mineral density (ebi-a-GCST90013422) All - Inverse variance weighted 0.912705471664868 0.405068240919625 0.0242456528315108
Other cereal Juvenile rheumatoid arthritis (ebi-a-GCST90018653) All - Inverse variance weighted 19.6226991004939 9.54811615815732 0.0398656496331976
Other cereal Rheumatoid arthritis (ebi-a-GCST90018910) rs10142984 -3.54471439552048 1.70395042872388 0.0374987608098818
Other cereal Rheumatoid arthritis (ebi-a-GCST90018910) All - Inverse variance weighted -1.39388071856164 0.582400097048658 0.0166958185092201
Other cereal Heel bone mineral density (ebi-a-GCST90029004) rs137892172 -0.55993857516316 0.244305954187309 0.0219081639585331
Other cereal Heel bone mineral density (ebi-a-GCST90029004) All - Inverse variance weighted -0.167719907277005 0.0729238368462785 0.0214520406910574
Other cereal Sciatica (ebi-a-GCST90038692) rs74383428 -0.058661902099844 0.0289205552328024 0.0425213870574944
Other cereal Sciatica (ebi-a-GCST90038692) All - Inverse variance weighted -0.0240156629106593 0.0078981268716933 0.0023604589351213
Other cereal Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) rs11710714 56.7634518514426 18.0862134062676 0.0016981906548455
Other cereal Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) rs11710714 56.8371227818143 18.1000267057123 0.0016885103331352
Other cereal Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) rs10142984 50.1856932839478 18.7185795272222 0.0073388671102042
Other cereal Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) rs7333641 44.9865813129792 21.2407021957609 0.034179956010076
Other cereal Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) All - MR Egger -25.1637604217532 8.82202827438484 0.0145583682153766
Other cereal Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) rs10142984 50.2727564445395 18.7683299047032 0.0073931735298592
Other cereal Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) rs7333641 45.6395263616569 21.2940038323877 0.0320886854115711
Other cereal Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) All - MR Egger -25.3600125420962 8.82903794418469 0.0140286809431054
Other cereal Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs113605228 -7.38989341409308 2.81183324933943 0.0085852996571163
Other cereal Achilles tendinitis (finn-b-M13_ACHILLESTEND) All - Inverse variance weighted -2.99949224713401 1.29397004907347 0.0204463949083646
Other cereal Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) rs10142984 43.357453974682 21.728477364822 0.0459970128165218
Other cereal Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) All - Inverse variance weighted 10.6233661864056 5.39548767311537 0.0489605203026357
Other cereal Other bursitis of hip (finn-b-M13_BURSITISHIPOTH) rs7737375 -19.3188462969647 9.31389418140411 0.0380610693034046
Other cereal Other bursitis of hip (finn-b-M13_BURSITISHIPOTH) All - Inverse variance weighted -6.50241714403416 3.26396394283342 0.0463508596389994
Other cereal Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs76538400 9.34973267665727 4.58927019410572 0.0416197148416647
Other cereal Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) All - Inverse variance weighted 4.53456680310994 1.7838656408696 0.0110223648270099
Other cereal Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) All - MR Egger 9.4233936482112 3.40793896423545 0.0171156880931401
Other cereal Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) rs137892172 17.9448273340524 7.02729383375075 0.0106618717053972
Other cereal Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) rs76538400 10.041086149227 5.04029603097264 0.0463532876836197
Other cereal Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) All - MR Egger 11.5523009465931 3.68173735684679 0.0085679462787253
Other cereal Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) rs113605228 -6.46203554119548 2.93900158724925 0.0278979838948124
Other cereal Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) rs74383428 13.8333205450021 7.03358215772032 0.0492116649734001
Other cereal Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) All - Inverse variance weighted -2.86459055435648 1.45832252881633 0.0494947068202697
Other cereal Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) All - MR Egger -21.3750901030318 9.74085336281304 0.0486249206068683
Other cereal Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) All - Inverse variance weighted -1.10399654304063 0.516079272667328 0.0324195113816848
Other cereal Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) rs10142984 -10.0744514399003 4.1292813309221 0.014697061589135
Other cereal Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) All - MR Egger 4.92583068966844 1.95414990805663 0.0268745011452776
Other cereal Heel bone mineral density (BMD) T-score automated (left) (ukb-a-361) All - Inverse variance weighted -0.458914199444805 0.167900459436879 0.0062712406844422
Other cereal Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs76538400 -1.19614356448682 0.60833838131107 0.0492700767781719
Other cereal Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) All - Inverse variance weighted -0.355928043942421 0.166875481461962 0.0329332600181737
Other cereal Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) rs10913092 -0.313516543493974 0.151123010429113 0.0380256193735264
Other cereal Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) rs74383428 -0.356506885602897 0.146322258638518 0.0148322146419421
Other cereal Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) All - Inverse variance weighted -0.101823354733152 0.0506610893539373 0.0444425443210205
Other cereal Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) All - MR Egger -0.220964236175866 0.086810637344139 0.0272190719842095
Other cereal Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) rs113630308 -0.015623795156979 0.0079436151382031 0.0492020201433804
Other cereal Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) All - Inverse variance weighted -0.0054868608314785 0.0021070999679607 0.0092146263693386
Other cereal Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) All - Inverse variance weighted 0.0128569154266806 0.0052767823150339 0.0148298950220393
Other cereal Heel bone mineral density (BMD) (left) (ukb-b-1096) rs76538400 -1.20593115436277 0.516411414575048 0.0195322452202544
Other cereal Heel bone mineral density (BMD) (left) (ukb-b-1096) All - Inverse variance weighted -0.361821397970953 0.152736375412414 0.017839750720775
Other cereal Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs137892172 -0.939445348348293 0.45731522275644 0.0399503269259434
Other cereal Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs76538400 -1.1559858042087 0.51667149516711 0.0252621042637655
Other cereal Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) All - Inverse variance weighted -0.36341878683755 0.155682252308351 0.0195767569886954
Other cereal Operative procedures - main OPCS: W87.9 Unspecified diagnostic endoscopic examination of knee joint (ukb-b-15942) All - Inverse variance weighted -0.032403293024253 0.0136399408816274 0.0175195759388067
Other cereal Non-cancer illness code, self-reported: ankylosing spondylitis (ukb-b-18194) All - Inverse variance weighted 0.0197465866527781 0.0091850163475174 0.0315655374969814
Other cereal Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs10913092 -1.08117891755543 0.482592084494992 0.0250677067255844
Other cereal Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs76538400 -1.15690102452 0.513497853512076 0.0242603326117804
Other cereal Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) All - Inverse variance weighted -0.367221643316049 0.14607002565002 0.0119366729110736
Other cereal Heel bone mineral density (BMD) (right) (ukb-b-4657) rs10913092 -1.06045935301146 0.482701243527902 0.0280256663793368
Other cereal Heel bone mineral density (BMD) (right) (ukb-b-4657) rs76538400 -1.16416352814138 0.51355382022176 0.0233977186290524
Other cereal Heel bone mineral density (BMD) (right) (ukb-b-4657) All - Inverse variance weighted -0.380475971007342 0.140124084349172 0.0066219975053231
Other cereal Knee pain for 3+ months (ukb-b-8906) rs137892172 0.51015520740023 0.243780918081936 0.0363778192788838
Other cereal Knee pain for 3+ months (ukb-b-8906) All - MR Egger 0.34663009005671 0.133850761957308 0.0236720392431333
Other cereal Heel bone mineral density (BMD) (left) (ukb-e-4105_AFR) All - Inverse variance weighted -1.80932906579287 0.829985975158357 0.0292610662882785
Other cereal Ankle spacing width (right) (ukb-e-4119_AFR) rs28496198 2.64767932489451 0.926009644364075 0.0042466386174984
Other cereal Ankle spacing width (right) (ukb-e-4119_AFR) All - Inverse variance weighted 1.58091535849699 0.615558123127589 0.0102209478030765