ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Cauliflower (ukb-b-905)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Cauliflower (👉 📊) Ankylosing spondylitis (ebi-a-GCST005529) Wald ratio 1 0.717557378 0.221768767 0.001213828
Cauliflower (👉 📊) Menstruation quality of life impact (stiff neck) (ebi-a-GCST006652) Weighted median 4 2.914034439 1.435338344 0.042335468
Cauliflower (👉 📊) Osteoarthritis (hip) (ebi-a-GCST007091) Inverse variance weighted 14 0.377894194 0.155748183 0.015253014
Cauliflower (👉 📊) Neck circumference (ebi-a-GCST90017133) Weighted median 13 1.72176642 0.750619612 0.02180236
Cauliflower (👉 📊) Osteoporosis (ebi-a-GCST90038656) Inverse variance weighted 13 -0.007274075 0.003562404 0.041161402
Cauliflower (👉 📊) Cervical root disorders (finn-b-G6_CERVROOT) Inverse variance weighted 14 -3.587194301 1.614850807 0.02632536
Cauliflower (👉 📊) Cervicalgia (finn-b-M13_CERVICALGIA) Inverse variance weighted 14 -0.684024714 0.329127102 0.037681776
Cauliflower (👉 📊) Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) Inverse variance weighted 14 -1.139905302 0.543012332 0.035797032
Cauliflower (👉 📊) Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) Weighted median 14 -0.914336317 0.373377146 0.014332197
Cauliflower (👉 📊) Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) Weighted median 14 -0.76796505 0.365001514 0.035378001
Cauliflower (👉 📊) Spondylosis (finn-b-M13_SPONDYLOSIS) MR Egger 14 -1.384939342 0.517448941 0.020167919
Cauliflower (👉 📊) Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) MR Egger 14 -3.329969471 1.347520593 0.029429672
Cauliflower (👉 📊) Open wound of shoulder and upper arm (finn-b-ST19_OPEN_WOUND_SHOUL_UPPER_ARM) MR Egger 14 -6.090704332 2.485199298 0.030548957
Cauliflower (👉 📊) Bone proteoglycan II (prot-c-2666_53_2) Inverse variance weighted 2 5.726121708 1.662819774 0.000573979
Cauliflower (👉 📊) Fractured bone site(s): Ankle (ukb-a-438) MR Egger 14 -0.02016184 0.008484779 0.035001853
Cauliflower (👉 📊) Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) MR Egger 14 -0.090180398 0.035424319 0.025666936
Cauliflower (👉 📊) Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) Weighted median 14 -0.048780767 0.020953402 0.019908945
Cauliflower (👉 📊) Non-cancer illness code self-reported: osteoporosis (ukb-a-87) Weighted median 14 -0.01080941 0.005456951 0.047607919
Cauliflower (👉 📊) Non-cancer illness code self-reported: osteoporosis (ukb-a-87) Inverse variance weighted 14 -0.009105469 0.004024454 0.023664334
Cauliflower (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) MR Egger 14 0.011228548 0.003857299 0.013057115
Cauliflower (👉 📊) Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) Weighted median 9 -0.011800638 0.00593292 0.046700069
Cauliflower (👉 📊) Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) Inverse variance weighted 9 -0.011529238 0.004386279 0.008576786
Cauliflower (👉 📊) Diagnoses - secondary ICD10: M13.99 Arthritis, unspecified (Site unspecified) (ukb-b-15026) Inverse variance weighted 6 0.008029889 0.003362469 0.016936061
Cauliflower (👉 📊) Operative procedures - secondary OPCS: Z85.6 Ankle joint (ukb-b-15453) Weighted median 6 0.008702448 0.00401996 0.030402269
Cauliflower (👉 📊) Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) MR Egger 14 -0.075225647 0.031328577 0.033446417
Cauliflower (👉 📊) Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) Weighted median 14 -0.042359168 0.018056996 0.018983282
Cauliflower (👉 📊) Ankle spacing width (left) (ukb-b-2122) Inverse variance weighted 14 0.123196523 0.045443128 0.006707972
Cauliflower (👉 📊) Diagnoses - secondary ICD10: M47.82 Other spondylosis (Cervical region) (ukb-b-2625) Inverse variance weighted 3 -0.007729163 0.002961328 0.009053359
Cauliflower (👉 📊) Operation code: shoulder surgery (ukb-b-5935) Weighted median 9 0.013501572 0.006354484 0.033609015
Cauliflower (👉 📊) Diagnoses - main ICD10: S82.80 Fractures of other parts of lower leg (closed) (ukb-b-5946) Weighted median 4 -0.009731195 0.003644048 0.007575289
Cauliflower (👉 📊) Diagnoses - main ICD10: S82.80 Fractures of other parts of lower leg (closed) (ukb-b-5946) Inverse variance weighted 4 -0.007154122 0.003241326 0.027302949
Cauliflower (👉 📊) Ankle spacing width (right) (ukb-b-8607) Inverse variance weighted 14 0.117064921 0.042721556 0.006140481
Cauliflower (👉 📊) Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) Inverse variance weighted 12 0.003627335 0.001850617 0.049987852
Cauliflower (👉 📊) Ankle spacing width (ukb-e-3143_AFR) MR Egger 9 8.688714281 2.499367215 0.010316773
Cauliflower (👉 📊) Heel bone mineral density (BMD) (right) (ukb-e-4124_AFR) Weighted median 9 -2.055649936 1.016946606 0.043238978

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Cauliflower Ankylosing spondylitis (ebi-a-GCST005529) rs62179283 0.717557378201867 0.221768766570295 0.0012138283839067
Cauliflower Menstruation quality of life impact (stiff neck) (ebi-a-GCST006652) rs328960 4.18206655206287 1.86139335707269 0.024656660625598
Cauliflower Osteoarthritis (hip) (ebi-a-GCST007091) rs12549871 1.77189800934274 0.618345639624004 0.0041629049983403
Cauliflower Osteoarthritis (hip) (ebi-a-GCST007091) rs79089855 1.26299087663626 0.596588655295518 0.0342580420916045
Cauliflower Osteoarthritis (hip) (ebi-a-GCST007091) All - Inverse variance weighted 0.377894193745935 0.155748183369001 0.0152530138820345
Cauliflower Neck circumference (ebi-a-GCST90017133) rs12549871 4.58303238780144 1.84464455518085 0.0129730942179722
Cauliflower Osteoporosis (ebi-a-GCST90038656) rs881150 -0.0249740519777705 0.0118487250735534 0.0350533378335431
Cauliflower Osteoporosis (ebi-a-GCST90038656) All - Inverse variance weighted -0.0072740751711079 0.0035624043254954 0.0411614022440472
Cauliflower Cervical root disorders (finn-b-G6_CERVROOT) rs328960 -16.5574349214145 7.11413310412574 0.0199439742952097
Cauliflower Cervical root disorders (finn-b-G6_CERVROOT) All - Inverse variance weighted -3.58719430149453 1.61485080739128 0.0263253595793717
Cauliflower Cervicalgia (finn-b-M13_CERVICALGIA) rs62179283 -3.00695280283572 1.48900001240833 0.043441046075439
Cauliflower Cervicalgia (finn-b-M13_CERVICALGIA) All - Inverse variance weighted -0.684024714324107 0.329127101712483 0.0376817759388122
Cauliflower Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) rs117040088 -2.84674160899308 1.43377205264632 0.0470898625175775
Cauliflower Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) rs17401217 -3.81884003128232 1.63349226771614 0.0193956619426975
Cauliflower Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) All - Inverse variance weighted -1.13990530247753 0.54301233229904 0.0357970323854574
Cauliflower Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) rs55662076 -2.90619817992216 1.23370961951598 0.0184899221134798
Cauliflower Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) rs55662076 -2.52725273097152 1.20236826659525 0.0355624102801609
Cauliflower Spondylosis (finn-b-M13_SPONDYLOSIS) rs117040088 -1.65619874384926 0.561667400088011 0.0031909505169033
Cauliflower Spondylosis (finn-b-M13_SPONDYLOSIS) rs144642750 -1.48668456018122 0.513010869358308 0.003755994673044
Cauliflower Spondylosis (finn-b-M13_SPONDYLOSIS) rs79089855 -1.70567235224117 0.779055930186434 0.0285670993280514
Cauliflower Spondylosis (finn-b-M13_SPONDYLOSIS) All - MR Egger -1.38493934237503 0.517448941287982 0.0201679192122629
Cauliflower Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) All - MR Egger -3.32996947078926 1.34752059287261 0.0294296723740386
Cauliflower Open wound of shoulder and upper arm (finn-b-ST19_OPEN_WOUND_SHOUL_UPPER_ARM) rs848788 9.9022860335983 4.94359170563982 0.0451713864433259
Cauliflower Open wound of shoulder and upper arm (finn-b-ST19_OPEN_WOUND_SHOUL_UPPER_ARM) All - MR Egger -6.09070433218049 2.48519929833495 0.030548957489866
Cauliflower Bone proteoglycan II (prot-c-2666_53_2) rs848788 7.07306145257022 2.40253522686656 0.0032400098229648
Cauliflower Bone proteoglycan II (prot-c-2666_53_2) All - Inverse variance weighted 5.72612170752948 1.66281977360866 0.0005739789043151
Cauliflower Fractured bone site(s): Ankle (ukb-a-438) rs149923272 -0.0335889809437131 0.0140555831824281 0.0168609845760566
Cauliflower Fractured bone site(s): Ankle (ukb-a-438) All - MR Egger -0.0201618398417941 0.008484778803927 0.0350018533006278
Cauliflower Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) rs144642750 -0.108469914149201 0.055119068014391 0.049077247764925
Cauliflower Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) rs74805957 -0.102600988257042 0.0516712386391914 0.0470722149749057
Cauliflower Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) All - MR Egger -0.0901803977328718 0.0354243188374312 0.0256669363443767
Cauliflower Non-cancer illness code self-reported: osteoporosis (ukb-a-87) All - Inverse variance weighted -0.0091054692778049 0.0040244535315146 0.0236643335615882
Cauliflower Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) rs17756840 -0.0140943317948452 0.0068282943525385 0.039007549881654
Cauliflower Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) rs55662076 0.0130291702519275 0.0064149196236758 0.0422475866383341
Cauliflower Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) All - MR Egger 0.0112285480423734 0.0038572994692691 0.0130571151415517
Cauliflower Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs881150 -0.0274486760379209 0.0122090143837856 0.0245615087013351
Cauliflower Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) All - Inverse variance weighted -0.0115292378397593 0.0043862787417187 0.0085767864789175
Cauliflower Diagnoses - secondary ICD10: M13.99 Arthritis, unspecified (Site unspecified) (ukb-b-15026) rs12549871 0.0182940415382777 0.0085243882794922 0.0318663875866517
Cauliflower Diagnoses - secondary ICD10: M13.99 Arthritis, unspecified (Site unspecified) (ukb-b-15026) All - Inverse variance weighted 0.0080298888729039 0.0033624692386082 0.0169360606656161
Cauliflower Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) rs62179283 -0.0908273463124501 0.0455261753793848 0.046036588158877
Cauliflower Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) All - MR Egger -0.0752256471169021 0.0313285772008116 0.0334464169609643
Cauliflower Ankle spacing width (left) (ukb-b-2122) rs12549871 0.327480007690349 0.163377829970538 0.0450236358263418
Cauliflower Ankle spacing width (left) (ukb-b-2122) rs144642750 0.323476671806293 0.16458987683932 0.0493737722289266
Cauliflower Ankle spacing width (left) (ukb-b-2122) rs149923272 0.345559631822404 0.148977753591233 0.0203658572930129
Cauliflower Ankle spacing width (left) (ukb-b-2122) rs62179283 0.323199447415551 0.160124579667705 0.0435470226353007
Cauliflower Ankle spacing width (left) (ukb-b-2122) All - Inverse variance weighted 0.123196523193034 0.0454431275312394 0.0067079716043974
Cauliflower Diagnoses - secondary ICD10: M47.82 Other spondylosis (Cervical region) (ukb-b-2625) rs17756840 -0.0123730747290359 0.0050976922678006 0.0152162267613687
Cauliflower Diagnoses - secondary ICD10: M47.82 Other spondylosis (Cervical region) (ukb-b-2625) All - Inverse variance weighted -0.007729162747506 0.002961328038354 0.0090533592140834
Cauliflower Operation code: shoulder surgery (ukb-b-5935) rs115503647 0.0236483573954488 0.0115688145177601 0.0409390280144332
Cauliflower Operation code: shoulder surgery (ukb-b-5935) rs12549871 0.0264252866993333 0.0133832339996571 0.0483241436335067
Cauliflower Diagnoses - main ICD10: S82.80 Fractures of other parts of lower leg (closed) (ukb-b-5946) All - Inverse variance weighted -0.0071541218794361 0.0032413259279994 0.0273029490407898
Cauliflower Ankle spacing width (right) (ukb-b-8607) rs12549871 0.362841584004074 0.16541525287219 0.0282699706772206
Cauliflower Ankle spacing width (right) (ukb-b-8607) rs62179283 0.357292997977442 0.162120666906561 0.0275334341879822
Cauliflower Ankle spacing width (right) (ukb-b-8607) All - Inverse variance weighted 0.117064921032562 0.0427215560578826 0.0061404811986716
Cauliflower Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs881150 0.0127395390650539 0.0059660019614253 0.0327319284445547
Cauliflower Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) All - Inverse variance weighted 0.0036273347645123 0.0018506168696663 0.04998785182373
Cauliflower Ankle spacing width (ukb-e-3143_AFR) rs117040088 5.07420890506861 1.89782773932872 0.0075021074913192
Cauliflower Ankle spacing width (ukb-e-3143_AFR) rs17756840 -4.22703936109527 1.64030493180522 0.009966659964478
Cauliflower Ankle spacing width (ukb-e-3143_AFR) All - MR Egger 8.68871428076489 2.49936721469927 0.0103167726085525