ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Sweet potato | Rheumatoid arthritis (ebi-a-GCST000679) | rs12359348 | 6.01181465755953 | 2.70219484468972 | 0.0260953740976733 |
| Sweet potato | Rheumatoid arthritis (ebi-a-GCST000679) | All - Inverse variance weighted | 4.21932095355213 | 1.62613861314872 | 0.009467705529261 |
| Sweet potato | Bone mineral density (paediatric, total body less head) (ebi-a-GCST004772) | rs11747767 | 3.42544453067588 | 1.6136114411562 | 0.0337669697873565 |
| Sweet potato | Bone mineral density (paediatric, total body less head) (ebi-a-GCST004772) | All - Inverse variance weighted | 1.63798189726931 | 0.784202306525395 | 0.0367326074471393 |
| Sweet potato | Total body bone mineral density (age 15-30) (ebi-a-GCST005344) | rs28360770 | 7.68459026191645 | 2.90980830093035 | 0.0082679619641864 |
| Sweet potato | Total body bone mineral density (age 15-30) (ebi-a-GCST005344) | All - Inverse variance weighted | 1.63964903845058 | 0.697750532161891 | 0.0187780892533404 |
| Sweet potato | Total body bone mineral density (age 0-15) (ebi-a-GCST005345) | rs62147120 | -3.17404213205146 | 1.56934822564683 | 0.0431223992289301 |
| Sweet potato | Total body bone mineral density (age over 60) (ebi-a-GCST005349) | rs258001 | -2.22935381620655 | 0.986439741684313 | 0.0238212508370941 |
| Sweet potato | Ulcerative colitis vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016625) | rs139200386 | 0.537706681005511 | 0.205306187293013 | 0.0088175637857739 |
| Sweet potato | Ulcerative colitis vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016625) | All - MR Egger | 0.571517387936456 | 0.219953827250829 | 0.0316989149218661 |
| Sweet potato | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | rs12359348 | -5.45067671948933 | 2.40956831806302 | 0.0236914248697718 |
| Sweet potato | Spine arthritis or spondylitis (ebi-a-GCST90038657) | rs77260147 | 0.0463804585766532 | 0.0218874456870383 | 0.0340867558986384 |
| Sweet potato | Spine arthritis or spondylitis (ebi-a-GCST90038657) | All - Inverse variance weighted | 0.0094192985267922 | 0.0046102356570666 | 0.041039833855023 |
| Sweet potato | Other bursitis of hip (finn-b-M13_BURSITISHIPOTH) | All - Inverse variance weighted | -4.25984174729461 | 1.97436717500842 | 0.0309610285156349 |
| Sweet potato | Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) | rs116449159 | 2.15017132249114 | 0.787490989523161 | 0.0063256077324045 |
| Sweet potato | Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) | All - Inverse variance weighted | 0.566218779708258 | 0.258540264329014 | 0.0285198608855978 |
| Sweet potato | Osteopathies and chondropathies (finn-b-M13_OSTEOCHONDRO) | rs142057497 | 4.85880629973888 | 2.10340771708183 | 0.0208898788941942 |
| Sweet potato | Otherdisorders of bone (finn-b-M13_OTHERBONE) | rs3015698 | 15.1325573263569 | 6.44355412880368 | 0.018850216807602 |
| Sweet potato | Patellar tendinitis (finn-b-M13_PATELLARTEND) | All - Inverse variance weighted | -5.96938738422324 | 2.13011607043703 | 0.0050727622234809 |
| Sweet potato | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs117054456 | 14.0868354650657 | 7.12172626816323 | 0.0479277418735791 |
| Sweet potato | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs840783 | 11.8570411718428 | 4.80463042745289 | 0.0135932483882367 |
| Sweet potato | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | All - MR Egger | -3.63598480269086 | 1.44774241160004 | 0.0198621912846345 |
| Sweet potato | Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) | rs12359348 | 10.755613419741 | 4.21674455661028 | 0.010750952178414 |
| Sweet potato | Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) | rs144212164 | 38.7661424084747 | 17.780250076639 | 0.0292358011671635 |
| Sweet potato | Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) | rs840783 | 11.4074851084554 | 5.1886262315963 | 0.0279095116038672 |
| Sweet potato | Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) | All - MR Egger | -5.05271564118888 | 1.56612816666256 | 0.0038840859874747 |
| Sweet potato | Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) | rs145152193 | 4.23825387819627 | 1.32627280971016 | 0.0013953440642276 |
| Sweet potato | Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) | All - Inverse variance weighted | 0.745099691238971 | 0.351915288200097 | 0.0342369373027266 |
| Sweet potato | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | rs116449159 | 11.8419883283467 | 4.53733052897671 | 0.0090568146171716 |
| Sweet potato | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | rs117495199 | 16.4962273545521 | 7.65253360910031 | 0.031110563211672 |
| Sweet potato | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | rs74882793 | -24.5391042192708 | 11.6834762264797 | 0.0357002087697497 |
| Sweet potato | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | rs840783 | 15.9967032555352 | 8.14820364889671 | 0.0496208033101203 |
| Sweet potato | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | All - Inverse variance weighted | 4.34249906735045 | 1.60598306216676 | 0.0068520449005772 |
| Sweet potato | Superficial injury of ankle and foot (finn-b-ST19_SUPERF_INJURY_ANKLE_FOOT) | All - Inverse variance weighted | 1.76175804840843 | 0.821870988214374 | 0.0320653998253744 |
| Sweet potato | Superficial injury of neck (finn-b-ST19_SUPERF_INJURY_NECK) | rs62147120 | 24.6076629435883 | 11.126820302559 | 0.0269968814536015 |
| Sweet potato | Superficial injury of shoulder and upper arm (finn-b-ST19_SUPERF_INJURY_SHOUL_UPPER_ARM) | rs117054456 | -15.7226137649004 | 7.22178717480205 | 0.0294724779529997 |
| Sweet potato | Superficial injury of shoulder and upper arm (finn-b-ST19_SUPERF_INJURY_SHOUL_UPPER_ARM) | rs117103006 | 14.1657988977218 | 6.30508216290351 | 0.0246574738747707 |
| Sweet potato | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs116449159 | 7.69716898223578 | 1.98971077603658 | 0.0001095130646826 |
| Sweet potato | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs117495199 | 7.45336857022483 | 3.38197556398177 | 0.0275348590298736 |
| Sweet potato | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs62484939 | -10.1724355373133 | 4.44846997856021 | 0.0222117741592811 |
| Sweet potato | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | rs76145743 | 7.12699307189976 | 3.22016962717065 | 0.0268814279997491 |
| Sweet potato | Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) | All - Inverse variance weighted | 1.84720672721982 | 0.685940718521399 | 0.0070822062630498 |
| Sweet potato | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs11747767 | 32.5199343420122 | 14.4342264010128 | 0.0242607990679343 |
| Sweet potato | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs117495199 | 38.4963039564901 | 15.4621011911601 | 0.012784373665886 |
| Sweet potato | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs142057497 | 38.5526458051432 | 16.9452098329396 | 0.0228978120006773 |
| Sweet potato | Shoulder region (finn-b-Z21_SHOUL_REGION) | All - Inverse variance weighted | 6.58483744969447 | 2.89769991280808 | 0.0230601925330172 |
| Sweet potato | Rheumatoid arthritis (ieu-a-834) | rs12359348 | 6.01181465755953 | 2.63927402038417 | 0.0227367733165292 |
| Sweet potato | Rheumatoid arthritis (ieu-a-834) | All - Inverse variance weighted | 4.3132130313739 | 1.63155127389932 | 0.0082022983933584 |
| Sweet potato | Osteocalcin (prot-a-246) | rs142057497 | -7.83044305891835 | 2.92904439107657 | 0.0075091567088171 |
| Sweet potato | Osteocalcin (prot-a-246) | All - Inverse variance weighted | -1.39780196584242 | 0.564083890899231 | 0.0132119777081016 |
| Sweet potato | Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC (ukb-b-14157) | All - Inverse variance weighted | 0.0207938722208715 | 0.0091025856856431 | 0.0223485142718886 |
| Sweet potato | Diagnoses - main ICD10: Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device (ukb-b-19542) | rs12359348 | 0.0326348823878045 | 0.0159087861799598 | 0.0402304653555168 |
| Sweet potato | Diagnoses - main ICD10: Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device (ukb-b-19542) | rs28360770 | 0.039787303124505 | 0.0188431995308355 | 0.0347298713898102 |
| Sweet potato | Diagnoses - secondary ICD10: M47.82 Other spondylosis (Cervical region) (ukb-b-2625) | All - Inverse variance weighted | 0.0128837316411309 | 0.0062052787731137 | 0.0378705134610846 |
| Sweet potato | Non-cancer illness code, self-reported: arthritis (nos) (ukb-b-8229) | All - Inverse variance weighted | 0.0194842900396944 | 0.0090437812802874 | 0.0312056314387257 |
| Sweet potato | Ankle spacing width (right) (ukb-b-8607) | rs117495199 | 0.810754912099276 | 0.385131563828565 | 0.0352793374827437 |
| Sweet potato | Ankle spacing width (right) (ukb-b-8607) | All - Inverse variance weighted | 0.158837267488062 | 0.072511801724697 | 0.0284878291445921 |
| Sweet potato | Osteoarthrosis (ukb-e-740_CSA) | rs28360770 | -16.0432673889133 | 7.61718157540841 | 0.0351874442023648 |
| Sweet potato | Osteoarthrosis (ukb-e-740_CSA) | All - MR Egger | 5.08842062711847 | 2.23659433084406 | 0.0420507736873153 |