ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Other milk-based pudding (ukb-b-9857)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Other milk-based pudding (👉 📊) Total body bone mineral density (ebi-a-GCST005348) Weighted median 23 -0.496120178 0.253032785 0.049914585
Other milk-based pudding (👉 📊) Total body bone mineral density (ebi-a-GCST005348) Inverse variance weighted 23 -0.418141882 0.177374721 0.018403771
Other milk-based pudding (👉 📊) Total body bone mineral density (age 45-60) (ebi-a-GCST005350) MR Egger 23 -1.781330379 0.812951952 0.03985563
Other milk-based pudding (👉 📊) Total body bone mineral density (age 45-60) (ebi-a-GCST005350) Inverse variance weighted 23 -1.079870835 0.341794728 0.001580871
Other milk-based pudding (👉 📊) Ankylosing spondylitis (ebi-a-GCST005529) Wald ratio 1 1.600678927 0.586437779 0.006343143
Other milk-based pudding (👉 📊) Heel bone mineral density (ebi-a-GCST006288) MR Egger 23 0.700382309 0.289109595 0.024539787
Other milk-based pudding (👉 📊) Frozen shoulder (ebi-a-GCST90000512) Weighted median 18 -1.403661614 0.651713572 0.031255749
Other milk-based pudding (👉 📊) Frozen shoulder (ebi-a-GCST90000512) Inverse variance weighted 18 -1.205309548 0.461751927 0.009046372
Other milk-based pudding (👉 📊) Shoulder impingement (ebi-a-GCST90014054) MR Egger 18 -4.009423632 1.887024507 0.04953946
Other milk-based pudding (👉 📊) Heel bone mineral density (ebi-a-GCST90029004) MR Egger 23 0.410238894 0.1871072 0.039745554
Other milk-based pudding (👉 📊) Osteoarthritis (ebi-a-GCST90038686) Inverse variance weighted 21 -0.03836504 0.019450633 0.048560376
Other milk-based pudding (👉 📊) Fractures (ebi-a-GCST90038703) Inverse variance weighted 21 0.017395541 0.007913091 0.027925991
Other milk-based pudding (👉 📊) Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder (finn-b-CD2_BENIGN_CONNSOFT_UPPERLIMB) Weighted median 22 -4.550944137 2.154494024 0.034660471
Other milk-based pudding (👉 📊) Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) MR Egger 22 -1.555420337 0.726254224 0.044711859
Other milk-based pudding (👉 📊) Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) Weighted median 22 13.49672139 5.643131198 0.016770184
Other milk-based pudding (👉 📊) Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) Inverse variance weighted 22 7.625439371 2.884736282 0.00820841
Other milk-based pudding (👉 📊) Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) Inverse variance weighted 22 -3.170941596 1.450671115 0.028826978
Other milk-based pudding (👉 📊) Loose body in joint (finn-b-M13_LOOSEJOINT) MR Egger 22 -10.27735305 4.75443632 0.042947506
Other milk-based pudding (👉 📊) Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) Weighted median 22 -8.377524648 4.025511411 0.037424007
Other milk-based pudding (👉 📊) Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) Weighted median 22 -1.210389586 0.486983567 0.012937561
Other milk-based pudding (👉 📊) Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) Inverse variance weighted 22 -1.067040798 0.365140597 0.003474859
Other milk-based pudding (👉 📊) Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) Inverse variance weighted 22 -0.600723394 0.275878919 0.029444079
Other milk-based pudding (👉 📊) Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) MR Egger 22 -4.542204823 1.937971559 0.029531159
Other milk-based pudding (👉 📊) Forearm bone mineral density (ieu-a-977) MR Egger 23 2.61782532 1.042646437 0.020300862
Other milk-based pudding (👉 📊) Bone sialoprotein 2 (prot-a-1396) Inverse variance weighted 21 1.685891328 0.73034791 0.020980231
Other milk-based pudding (👉 📊) Alkaline phosphatase, bone (prot-c-2795_23_3) Inverse variance weighted 2 12.21563687 4.034894861 0.002465872
Other milk-based pudding (👉 📊) Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) MR Egger 22 0.025113824 0.011889073 0.04743041
Other milk-based pudding (👉 📊) Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) MR Egger 23 0.064065663 0.017519798 0.001471668
Other milk-based pudding (👉 📊) Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) Inverse variance weighted 14 1.440534041 0.552792052 0.009162681
Other milk-based pudding (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) Inverse variance weighted 14 1.397536306 0.555316807 0.011847751

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other milk-based pudding Total body bone mineral density (ebi-a-GCST005348) rs77851248 -2.20124016033798 1.01025961598284 0.0293401655052411
Other milk-based pudding Total body bone mineral density (ebi-a-GCST005348) All - Inverse variance weighted -0.418141882071838 0.177374721400597 0.0184037706858692
Other milk-based pudding Total body bone mineral density (age 45-60) (ebi-a-GCST005350) rs16939038 -3.02606291513537 1.47510030682086 0.0402252290221024
Other milk-based pudding Total body bone mineral density (age 45-60) (ebi-a-GCST005350) rs76865693 -3.97416498377952 1.73685728920735 0.0221296260301262
Other milk-based pudding Total body bone mineral density (age 45-60) (ebi-a-GCST005350) rs77851248 -6.18895113720866 1.80424664555293 0.0006031065794616
Other milk-based pudding Total body bone mineral density (age 45-60) (ebi-a-GCST005350) All - Inverse variance weighted -1.0798708346606 0.341794728466348 0.0015808709116745
Other milk-based pudding Total body bone mineral density (age 45-60) (ebi-a-GCST005350) All - MR Egger -1.78133037859364 0.812951951926293 0.0398556298769583
Other milk-based pudding Ankylosing spondylitis (ebi-a-GCST005529) rs11716159 1.60067892746648 0.586437779305603 0.0063431430339987
Other milk-based pudding Heel bone mineral density (ebi-a-GCST006288) rs114101642 0.996812323108082 0.475034694160112 0.0358699143152712
Other milk-based pudding Heel bone mineral density (ebi-a-GCST006288) rs116562464 -1.2988684235383 0.391665249834703 0.0009122705682424
Other milk-based pudding Heel bone mineral density (ebi-a-GCST006288) rs11716159 -1.1229975936748 0.477796493640426 0.0187548580078517
Other milk-based pudding Heel bone mineral density (ebi-a-GCST006288) rs17753403 -1.05035413306493 0.454191640232156 0.0207457870598247
Other milk-based pudding Heel bone mineral density (ebi-a-GCST006288) rs74489155 1.01805738255342 0.466355131589841 0.0290351578045206
Other milk-based pudding Heel bone mineral density (ebi-a-GCST006288) All - MR Egger 0.700382308522301 0.289109595044208 0.0245397874941978
Other milk-based pudding Frozen shoulder (ebi-a-GCST90000512) rs11716159 -5.27289446545204 1.97347026469577 0.0075425482752185
Other milk-based pudding Frozen shoulder (ebi-a-GCST90000512) rs76865693 -5.02760131176883 1.95655501716251 0.010181036317514
Other milk-based pudding Frozen shoulder (ebi-a-GCST90000512) All - Inverse variance weighted -1.20530954763904 0.461751927412686 0.0090463715511472
Other milk-based pudding Shoulder impingement (ebi-a-GCST90014054) rs16939038 6.73138844870023 3.3903115411848 0.0470913327785302
Other milk-based pudding Shoulder impingement (ebi-a-GCST90014054) All - MR Egger -4.00942363167087 1.88702450672785 0.0495394598973662
Other milk-based pudding Heel bone mineral density (ebi-a-GCST90029004) rs111689342 0.952537002046922 0.258871962420616 0.0002336293417585
Other milk-based pudding Heel bone mineral density (ebi-a-GCST90029004) rs114101642 0.539087680433782 0.257090327171565 0.0360041597329288
Other milk-based pudding Heel bone mineral density (ebi-a-GCST90029004) rs11716159 -0.910699553111035 0.26531196287384 0.0005979088932094
Other milk-based pudding Heel bone mineral density (ebi-a-GCST90029004) rs1487968 -0.534713076199436 0.264060244218213 0.0428708323683932
Other milk-based pudding Heel bone mineral density (ebi-a-GCST90029004) rs17753403 -0.647414849251102 0.252489450258433 0.0103435886864355
Other milk-based pudding Heel bone mineral density (ebi-a-GCST90029004) rs74489155 0.502690669585775 0.254782032766376 0.048493005038165
Other milk-based pudding Heel bone mineral density (ebi-a-GCST90029004) rs76021157 -0.669359866183578 0.247382617444279 0.0068146722317638
Other milk-based pudding Heel bone mineral density (ebi-a-GCST90029004) All - MR Egger 0.410238894217248 0.18710720018357 0.0397455543262585
Other milk-based pudding Osteoarthritis (ebi-a-GCST90038686) rs111689342 -0.174468587623996 0.0770787408807012 0.02360419949163
Other milk-based pudding Osteoarthritis (ebi-a-GCST90038686) rs73223239 -0.253196181546196 0.0795027990685193 0.0014488136263342
Other milk-based pudding Osteoarthritis (ebi-a-GCST90038686) All - Inverse variance weighted -0.0383650400305435 0.0194506330525463 0.0485603764695449
Other milk-based pudding Fractures (ebi-a-GCST90038703) All - Inverse variance weighted 0.0173955410620374 0.0079130907036469 0.0279259906170526
Other milk-based pudding Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs78116090 4.71911543398769 2.4031290952906 0.0495605070193472
Other milk-based pudding Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) All - MR Egger -1.55542033705085 0.726254223520202 0.0447118585503894
Other milk-based pudding Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) rs137977536 78.4771578791394 29.7680787684007 0.0083819146486628
Other milk-based pudding Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) rs76632750 29.9036304499257 13.8712915274875 0.0310998476770275
Other milk-based pudding Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) rs77851248 22.9100809689012 10.467000654743 0.0286120054257102
Other milk-based pudding Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) rs144298547 28.7273639385666 10.9212419308802 0.0085281488841985
Other milk-based pudding Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) rs1487968 31.1559848364893 14.8933990294608 0.0364445580910407
Other milk-based pudding Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) All - Inverse variance weighted 7.62543937131909 2.88473628246423 0.008208410158607
Other milk-based pudding Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs12189434 28.0035787321063 12.9792944785276 0.0309622245388782
Other milk-based pudding Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs73223239 -11.4044692565119 5.59042610613328 0.0413503257321401
Other milk-based pudding Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) All - Inverse variance weighted -3.17094159561761 1.45067111520513 0.0288269779268655
Other milk-based pudding Loose body in joint (finn-b-M13_LOOSEJOINT) All - MR Egger -10.2773530542863 4.75443631996455 0.0429475056451556
Other milk-based pudding Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) rs1328041 -35.4240775185384 16.2171229531248 0.0289356111676338
Other milk-based pudding Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) rs17753403 42.4361549852943 18.8925968245587 0.0246925422639399
Other milk-based pudding Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) rs4487085 -27.0050268479378 13.4739517879584 0.0450444075753624
Other milk-based pudding Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) rs73146365 56.0004920416654 23.6179999384948 0.0177355318461433
Other milk-based pudding Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) All - Inverse variance weighted -1.06704079789235 0.365140597440255 0.003474859330344
Other milk-based pudding Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) rs117055820 -1.92751355016439 0.899790617443998 0.0321789926357655
Other milk-based pudding Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) rs144298547 -2.16233670753964 0.934129457657123 0.0206230688132937
Other milk-based pudding Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) All - Inverse variance weighted -0.600723393720717 0.27587891886235 0.0294440793510932
Other milk-based pudding Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) All - MR Egger -4.54220482260044 1.93797155924363 0.0295311594513081
Other milk-based pudding Forearm bone mineral density (ieu-a-977) rs11716159 -4.58404950154692 2.29778274321073 0.0460441648301751
Other milk-based pudding Forearm bone mineral density (ieu-a-977) rs17753403 -4.35983796916959 2.14232972943986 0.0418416226533335
Other milk-based pudding Forearm bone mineral density (ieu-a-977) All - MR Egger 2.61782531994938 1.04264643722744 0.0203008619430939
Other milk-based pudding Bone sialoprotein 2 (prot-a-1396) rs114101642 6.91951276841688 3.16191788673121 0.0286411304824486
Other milk-based pudding Bone sialoprotein 2 (prot-a-1396) rs78116090 8.33218818813451 3.03323825835146 0.006015022679407
Other milk-based pudding Bone sialoprotein 2 (prot-a-1396) All - Inverse variance weighted 1.68589132779031 0.730347910497515 0.0209802308746384
Other milk-based pudding Alkaline phosphatase, bone (prot-c-2795_23_3) rs16939038 13.3686233521022 5.63601267743349 0.0176920798293684
Other milk-based pudding Alkaline phosphatase, bone (prot-c-2795_23_3) All - Inverse variance weighted 12.2156368711979 4.03489486116638 0.0024658719443048
Other milk-based pudding Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) rs137977536 0.0629991364906777 0.0220304731928896 0.0042412737937973
Other milk-based pudding Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) All - MR Egger 0.0251138240737658 0.0118890734479202 0.047430409672603
Other milk-based pudding Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) rs73146365 0.0926672612170123 0.0366242866494159 0.0113993168095902
Other milk-based pudding Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) rs78428634 0.0990571699976843 0.036770133792067 0.0070609211929694
Other milk-based pudding Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) All - MR Egger 0.0640656629186443 0.0175197982834643 0.0014716675554819
Other milk-based pudding Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) rs11716159 8.00618769336542 3.71347542110691 0.0310850385787033
Other milk-based pudding Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) All - Inverse variance weighted 1.44053404091566 0.552792051741678 0.0091626806138684
Other milk-based pudding Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) All - Inverse variance weighted 1.3975363064441 0.555316806763815 0.0118477507347846