ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Osteoporosis (bbj-a-137)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Other drink (ukb-b-1310) (👉 📊) Osteoporosis Inverse variance weighted 8 -1.036642429 0.497192011 0.037069833
Cottage cheese (ukb-b-14171) (👉 📊) Osteoporosis MR Egger 6 -8.674526327 2.759357729 0.034724628
Cottage cheese (ukb-b-14171) (👉 📊) Osteoporosis Inverse variance weighted 6 -3.890784818 1.426125082 0.006367687
Cheese (ukb-b-1489) (👉 📊) Osteoporosis MR Egger 164 1.316314422 0.436787496 0.002996831
Cheese (ukb-b-1489) (👉 📊) Osteoporosis Weighted median 164 0.433590447 0.185528409 0.019436226
Cheese (ukb-b-1489) (👉 📊) Osteoporosis Weighted mode 164 0.642975079 0.288583988 0.027246741
Broad bean (ukb-b-15212) (👉 📊) Osteoporosis Inverse variance weighted 9 0.483228354 0.227530448 0.03368717
Broccoli (ukb-b-15601) (👉 📊) Osteoporosis Inverse variance weighted 4 1.30484087 0.631639232 0.038847287
Poultry (ukb-b-16010) (👉 📊) Osteoporosis Inverse variance weighted 4 -1.169076071 0.480491829 0.014970906
Cereal bar (ukb-b-18788) (👉 📊) Osteoporosis MR Egger 6 0.963664776 0.316538316 0.038237673
Salad / raw vegetable (ukb-b-1996) (👉 📊) Osteoporosis MR Egger 84 1.704995545 0.635753783 0.008851307
Standard tea (ukb-b-3291) (👉 📊) Osteoporosis Weighted median 8 0.002907646 0.001382607 0.035464231
Drinking water (ukb-b-3975) (👉 📊) Osteoporosis Simple mode 16 0.336417097 0.12843687 0.019340176
Milk chocolate (ukb-b-4569) (👉 📊) Osteoporosis Inverse variance weighted 8 0.530121533 0.259878962 0.041362419
White fish (ukb-b-5427) (👉 📊) Osteoporosis Inverse variance weighted 4 1.934283645 0.979906712 0.048387801
Other grain (ukb-b-8765) (👉 📊) Osteoporosis MR Egger 20 -2.346121872 1.045534488 0.037650115

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other drink (ukb-b-1310) Osteoporosis All - Inverse variance weighted -1.0366424291464 0.497192011495612 0.0370698326939522
Cottage cheese (ukb-b-14171) Osteoporosis rs566351 -6.86026445781833 3.48095453803083 0.0487467812325961
Cottage cheese (ukb-b-14171) Osteoporosis rs80187236 -7.15836444330508 2.03931472609873 0.0004478012331049
Cottage cheese (ukb-b-14171) Osteoporosis All - Inverse variance weighted -3.89078481772344 1.42612508178454 0.0063676873916747
Cottage cheese (ukb-b-14171) Osteoporosis All - MR Egger -8.67452632720719 2.75935772915406 0.0347246277164627
Cheese (ukb-b-1489) Osteoporosis rs10499731 3.30780372985696 1.36390115642885 0.0152977723500642
Cheese (ukb-b-1489) Osteoporosis rs113367286 -3.38189819298142 1.32028959729112 0.0104226606911797
Cheese (ukb-b-1489) Osteoporosis rs13181793 4.60467455940212 1.95995544616711 0.0188048479122056
Cheese (ukb-b-1489) Osteoporosis rs1473781 4.97483220052779 2.08191838708856 0.0168693778436368
Cheese (ukb-b-1489) Osteoporosis rs2092412 5.18347260408152 2.47129694054704 0.0359519396902311
Cheese (ukb-b-1489) Osteoporosis rs2854175 -5.32472033753685 2.37129642161507 0.0247367493122328
Cheese (ukb-b-1489) Osteoporosis rs289232 4.83121853927249 1.89554563586285 0.0108118501558191
Cheese (ukb-b-1489) Osteoporosis rs4296548 -3.87190295212868 1.40296364543745 0.0057836267095981
Cheese (ukb-b-1489) Osteoporosis rs4675530 -3.40567287043665 1.57677165354331 0.030780226350391
Cheese (ukb-b-1489) Osteoporosis rs75499503 8.26315677831279 2.71918064894753 0.0023749041158344
Cheese (ukb-b-1489) Osteoporosis All - MR Egger 1.3163144221183 0.436787495954443 0.002996831053644
Broad bean (ukb-b-15212) Osteoporosis All - Inverse variance weighted 0.483228353580326 0.227530448357237 0.033687169792856
Broccoli (ukb-b-15601) Osteoporosis rs10982277 2.20310521389638 0.862131516646045 0.0106060765243534
Broccoli (ukb-b-15601) Osteoporosis All - Inverse variance weighted 1.30484086985251 0.631639232097151 0.038847286728789
Poultry (ukb-b-16010) Osteoporosis All - Inverse variance weighted -1.16907607116014 0.480491829218167 0.0149709056994336
Cereal bar (ukb-b-18788) Osteoporosis rs76116349 0.691107312308122 0.246545318169132 0.0050603705808508
Cereal bar (ukb-b-18788) Osteoporosis All - MR Egger 0.963664776438949 0.316538315602563 0.0382376725561602
Salad / raw vegetable (ukb-b-1996) Osteoporosis rs10960118 -5.70045641708342 2.59099519797288 0.0277995851036903
Salad / raw vegetable (ukb-b-1996) Osteoporosis rs12324270 1.56274369527986 0.773482237149768 0.0433418888657332
Salad / raw vegetable (ukb-b-1996) Osteoporosis All - MR Egger 1.70499554495426 0.635753783175823 0.008851306893668
Milk chocolate (ukb-b-4569) Osteoporosis All - Inverse variance weighted 0.530121532916094 0.259878962165327 0.0413624189189552
White fish (ukb-b-5427) Osteoporosis All - Inverse variance weighted 1.93428364543299 0.979906712280609 0.0483878010187412
Other grain (ukb-b-8765) Osteoporosis rs75760731 -6.3761462908032 2.64125764476694 0.0157759976814212
Other grain (ukb-b-8765) Osteoporosis rs79962891 -12.4570735004423 5.28127192482504 0.0183377890424639
Other grain (ukb-b-8765) Osteoporosis All - MR Egger -2.34612187155104 1.04553448778137 0.0376501145788767