Rheumatoid arthritis (ebi-a-GCST000679)

Mendelian Randomization Results

Intake (exposure)	Outcome	Method	Number of SNPs	b	se	P-value
Sweetened cereal (ukb-b-10640) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	2	-7.475268133	2.56660092	0.00358529
Vegetable pieces (ukb-b-12566) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	3	1.065565465	0.53159914	0.045021562
Crisp (ukb-b-12602) (👉 📊)	Rheumatoid arthritis	Weighted median	3	-2.579825948	0.843730053	0.002230846
Crisp (ukb-b-12602) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	3	-2.090556932	0.728003892	0.004083624
Lamb/mutton (ukb-b-14179) (👉 📊)	Rheumatoid arthritis	MR Egger	67	3.664936314	1.764408751	0.04174421
Cheese (ukb-b-1489) (👉 📊)	Rheumatoid arthritis	Weighted median	119	-0.620130912	0.301652296	0.039803677
Cheese (ukb-b-1489) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	119	-0.539244707	0.214776931	0.012048527
Salted nuts (ukb-b-15960) (👉 📊)	Rheumatoid arthritis	Weighted median	5	-3.863606553	1.862764658	0.038067713
Salted nuts (ukb-b-15960) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	5	-4.613720978	1.435919856	0.001313211
Garlic (ukb-b-17223) (👉 📊)	Rheumatoid arthritis	Weighted median	4	-1.884137599	0.909284178	0.038255106
Oily fish (ukb-b-2209) (👉 📊)	Rheumatoid arthritis	Weighted median	91	-0.968110561	0.359124054	0.007022924
Oily fish (ukb-b-2209) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	91	-0.654693814	0.236899379	0.005716854
Milk (ukb-b-2966) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	8	1.666482364	0.787050991	0.034228005
Watercress (ukb-b-6181) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	2	4.093926845	1.72665954	0.017739556
Blue cheese (ukb-b-7429) (👉 📊)	Rheumatoid arthritis	Weighted median	3	-5.360682267	2.659040301	0.043797734
Blue cheese (ukb-b-7429) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	3	-4.966081195	2.227713966	0.025798773
Sweet potato (ukb-b-9686) (👉 📊)	Rheumatoid arthritis	Weighted median	4	4.622674693	1.901165162	0.015036632
Sweet potato (ukb-b-9686) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	4	4.219320954	1.626138613	0.009467706

Mendelian Randomization Results (Single SNP)

Intake (exposure)	Outcome	SNP	b	se	P-value
Sweetened cereal (ukb-b-10640)	Rheumatoid arthritis	rs76927558	-8.974266352642	3.68327337003376	0.0148304946870625
Sweetened cereal (ukb-b-10640)	Rheumatoid arthritis	All - Inverse variance weighted	-7.47526813311314	2.56660092024167	0.0035852898819664
Vegetable pieces (ukb-b-12566)	Rheumatoid arthritis	All - Inverse variance weighted	1.06556546477363	0.531599140008235	0.0450215620584378
Crisp (ukb-b-12602)	Rheumatoid arthritis	rs12959170	-2.83261318438545	0.945428713060653	0.0027344325534528
Crisp (ukb-b-12602)	Rheumatoid arthritis	All - Inverse variance weighted	-2.09055693225657	0.728003892133952	0.0040836235089806
Lamb/mutton (ukb-b-14179)	Rheumatoid arthritis	rs416769	-9.43047350734341	3.4524920276427	0.0063047210163853
Lamb/mutton (ukb-b-14179)	Rheumatoid arthritis	All - MR Egger	3.6649363139167	1.7644087514086	0.0417442096822101
Cheese (ukb-b-1489)	Rheumatoid arthritis	rs113367286	-6.21294887250736	3.0787762604004	0.0435919927116238
Cheese (ukb-b-1489)	Rheumatoid arthritis	rs17207890	-7.14079199780762	2.31592559605371	0.0020468937342135
Cheese (ukb-b-1489)	Rheumatoid arthritis	rs281219	-5.39836049720675	2.18227194620289	0.0133709177073233
Cheese (ukb-b-1489)	Rheumatoid arthritis	rs34205186	-5.50230880367142	2.29804814020907	0.0166503018616349
Cheese (ukb-b-1489)	Rheumatoid arthritis	rs531358	-4.42550848358726	1.97958470675801	0.0253796766230371
Cheese (ukb-b-1489)	Rheumatoid arthritis	rs62034322	-3.50114455886046	1.6561372035449	0.0345116311152142
Cheese (ukb-b-1489)	Rheumatoid arthritis	rs6897252	-12.2656224586058	5.95662145018054	0.0394791413731527
Cheese (ukb-b-1489)	Rheumatoid arthritis	All - Inverse variance weighted	-0.539244706795966	0.214776931202603	0.0120485268205277
Salted nuts (ukb-b-15960)	Rheumatoid arthritis	rs1381597	-8.77113445921528	3.18369650741315	0.0058689285528572
Salted nuts (ukb-b-15960)	Rheumatoid arthritis	rs906822	-6.94027442016718	3.47974125722115	0.0460996210782817
Salted nuts (ukb-b-15960)	Rheumatoid arthritis	All - Inverse variance weighted	-4.61372097842694	1.43591985594759	0.0013132110488179
Oily fish (ukb-b-2209)	Rheumatoid arthritis	rs10061973	-4.72657826595774	2.2493618746602	0.0356148675797103
Oily fish (ukb-b-2209)	Rheumatoid arthritis	rs2271308	5.17166904875337	2.23024330717217	0.0204014843040987
Oily fish (ukb-b-2209)	Rheumatoid arthritis	rs37013	-7.28275628140451	2.40244341793506	0.002434261266816
Oily fish (ukb-b-2209)	Rheumatoid arthritis	rs957523	-5.38573023530155	2.71770133344568	0.0475102929286856
Oily fish (ukb-b-2209)	Rheumatoid arthritis	All - Inverse variance weighted	-0.654693813788687	0.23689937851216	0.0057168539781083
Milk (ukb-b-2966)	Rheumatoid arthritis	rs2807888	4.06651039788436	1.96084865969467	0.0380930351800966
Milk (ukb-b-2966)	Rheumatoid arthritis	All - Inverse variance weighted	1.66648236374765	0.787050990655407	0.0342280048622334
Watercress (ukb-b-6181)	Rheumatoid arthritis	rs1447897	5.44461522367161	2.215012835266	0.0139693210114947
Watercress (ukb-b-6181)	Rheumatoid arthritis	All - Inverse variance weighted	4.09392684529677	1.72665954044555	0.0177395564488399
Blue cheese (ukb-b-7429)	Rheumatoid arthritis	rs7671974	-7.52587363425281	3.55665319417297	0.0343449157681547
Blue cheese (ukb-b-7429)	Rheumatoid arthritis	All - Inverse variance weighted	-4.96608119518364	2.2277139657773	0.0257987728562162
Sweet potato (ukb-b-9686)	Rheumatoid arthritis	rs12359348	6.01181465755953	2.70219484468972	0.0260953740976733
Sweet potato (ukb-b-9686)	Rheumatoid arthritis	All - Inverse variance weighted	4.21932095355213	1.62613861314872	0.009467705529261