ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Bone mineral density (paediatric, total body less head) (ebi-a-GCST004772)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Tinned tomato (ukb-b-10565) (👉 📊) Bone mineral density (paediatric, total body less head) Inverse variance weighted 3 0.906932515 0.455210137 0.04633397
Salted peanuts (ukb-b-1099) (👉 📊) Bone mineral density (paediatric, total body less head) Inverse variance weighted 5 -1.155669048 0.56284278 0.040046252
Beetroot (ukb-b-11880) (👉 📊) Bone mineral density (paediatric, total body less head) Inverse variance weighted 3 1.205980097 0.485738395 0.013036268
Other sweets (ukb-b-139) (👉 📊) Bone mineral density (paediatric, total body less head) Inverse variance weighted 8 0.759014079 0.368697102 0.039528874
Battered fish (ukb-b-14166) (👉 📊) Bone mineral density (paediatric, total body less head) Inverse variance weighted 3 2.151098164 1.070193763 0.044430328
Shellfish (ukb-b-143) (👉 📊) Bone mineral density (paediatric, total body less head) Inverse variance weighted 5 2.858029901 1.389792081 0.039739717
Cheese (ukb-b-1489) (👉 📊) Bone mineral density (paediatric, total body less head) Weighted median 142 0.323183512 0.141084441 0.021980203
Cheese (ukb-b-1489) (👉 📊) Bone mineral density (paediatric, total body less head) Inverse variance weighted 142 0.230852439 0.098604479 0.019222058
Dried fruit (ukb-b-16576) (👉 📊) Bone mineral density (paediatric, total body less head) Weighted median 120 -0.429475645 0.207142317 0.03814101
Indian snacks (ukb-b-282) (👉 📊) Bone mineral density (paediatric, total body less head) Inverse variance weighted 2 2.952554576 1.260196846 0.019132908
Fizzy drink (ukb-b-2832) (👉 📊) Bone mineral density (paediatric, total body less head) Weighted median 7 -0.827162036 0.37311862 0.026630774
Fizzy drink (ukb-b-2832) (👉 📊) Bone mineral density (paediatric, total body less head) Inverse variance weighted 7 -0.688823601 0.344277952 0.045416367
Croissant (ukb-b-4007) (👉 📊) Bone mineral density (paediatric, total body less head) Weighted median 6 2.226547492 0.987504506 0.024150825
Other egg (ukb-b-8266) (👉 📊) Bone mineral density (paediatric, total body less head) Wald ratio 1 -4.679935727 2.38283902 0.04952815
Sweet potato (ukb-b-9686) (👉 📊) Bone mineral density (paediatric, total body less head) Inverse variance weighted 4 1.637981897 0.784202307 0.036732607

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Tinned tomato (ukb-b-10565) Bone mineral density (paediatric, total body less head) All - Inverse variance weighted 0.906932515107065 0.455210136503905 0.0463339700236585
Salted peanuts (ukb-b-1099) Bone mineral density (paediatric, total body less head) All - Inverse variance weighted -1.15566904789032 0.56284277955563 0.0400462516739485
Beetroot (ukb-b-11880) Bone mineral density (paediatric, total body less head) rs13101707 1.87319455771399 0.849521594003324 0.0274541405472447
Beetroot (ukb-b-11880) Bone mineral density (paediatric, total body less head) All - Inverse variance weighted 1.20598009732245 0.485738395414397 0.013036268293083
Other sweets (ukb-b-139) Bone mineral density (paediatric, total body less head) All - Inverse variance weighted 0.759014078762512 0.368697102144356 0.0395288740609569
Battered fish (ukb-b-14166) Bone mineral density (paediatric, total body less head) rs1432197 3.4756242568371 1.77112757750645 0.0497183303356367
Battered fish (ukb-b-14166) Bone mineral density (paediatric, total body less head) All - Inverse variance weighted 2.1510981642736 1.07019376268553 0.0444303283398755
Shellfish (ukb-b-143) Bone mineral density (paediatric, total body less head) rs1991446 5.80914955360431 2.68711055814475 0.0306291778276595
Shellfish (ukb-b-143) Bone mineral density (paediatric, total body less head) All - Inverse variance weighted 2.85802990149511 1.38979208064858 0.0397397169549093
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) rs10896050 -2.53706922223125 0.958840250142126 0.008145536122592
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) rs10938397 2.87204004060722 1.11064680375538 0.0097120418422043
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) rs11756671 -2.89044121707438 1.37703167853922 0.0358135897110861
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) rs12786959 2.53677385633929 1.12137861516253 0.0236855365374641
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) rs1514755 2.34962656260496 1.00889776426116 0.0198641244775157
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) rs1873036 2.7893840378198 1.28298804226919 0.0296953006436926
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) rs2968940 2.809229390681 1.20662267839687 0.0199027851118484
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) rs6089798 3.84941224809486 1.32867882616539 0.0037654220717047
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) rs660240 -2.90227757121299 1.29650430156039 0.0251858201762084
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) rs660240 -2.90227757121299 1.29650430156039 0.0251858201762084
Cheese (ukb-b-1489) Bone mineral density (paediatric, total body less head) All - Inverse variance weighted 0.230852439187806 0.09860447854819 0.0192220581441234
Dried fruit (ukb-b-16576) Bone mineral density (paediatric, total body less head) rs10087278 3.27771150833215 1.59905328656886 0.0403856561060009
Dried fruit (ukb-b-16576) Bone mineral density (paediatric, total body less head) rs1582322 -4.50334189507475 1.4219396467628 0.0015399833129696
Dried fruit (ukb-b-16576) Bone mineral density (paediatric, total body less head) rs17175518 -3.54114403020128 1.38295262782485 0.010450125692449
Dried fruit (ukb-b-16576) Bone mineral density (paediatric, total body less head) rs35792972 3.8301591855714 1.83012950522869 0.0363638812641406
Dried fruit (ukb-b-16576) Bone mineral density (paediatric, total body less head) rs62084586 2.81722485180595 1.38222119361534 0.0415312651911696
Dried fruit (ukb-b-16576) Bone mineral density (paediatric, total body less head) rs62162747 -4.71816870007286 1.60519477114759 0.0032894146573527
Dried fruit (ukb-b-16576) Bone mineral density (paediatric, total body less head) rs7047847 -3.79449867069997 1.58411228122916 0.0166046405682843
Indian snacks (ukb-b-282) Bone mineral density (paediatric, total body less head) rs4916724 3.96690548814608 1.78709143111788 0.0264353898684998
Indian snacks (ukb-b-282) Bone mineral density (paediatric, total body less head) All - Inverse variance weighted 2.95255457602125 1.26019684588362 0.0191329081218845
Fizzy drink (ukb-b-2832) Bone mineral density (paediatric, total body less head) rs35421650 -1.74147094369294 0.820813372744878 0.0338679336265162
Fizzy drink (ukb-b-2832) Bone mineral density (paediatric, total body less head) All - Inverse variance weighted -0.68882360088334 0.344277951850467 0.0454163665940113
Croissant (ukb-b-4007) Bone mineral density (paediatric, total body less head) rs3791299 3.33346311306174 1.68258238063215 0.047573453072034
Other egg (ukb-b-8266) Bone mineral density (paediatric, total body less head) rs10865141 -4.67993572727904 2.38283902023557 0.0495281504967197
Sweet potato (ukb-b-9686) Bone mineral density (paediatric, total body less head) rs11747767 3.42544453067588 1.6136114411562 0.0337669697873565
Sweet potato (ukb-b-9686) Bone mineral density (paediatric, total body less head) All - Inverse variance weighted 1.63798189726931 0.784202306525395 0.0367326074471393