Total body bone mineral density (age 30-45) (ebi-a-GCST005346)

Mendelian Randomization Results

Intake (exposure)	Outcome	Method	Number of SNPs	b	se	P-value
Sweets (ukb-b-10217) (👉 📊)	Total body bone mineral density (age 30-45)	Inverse variance weighted	21	-0.549437676	0.199439872	0.005870938
Omelette (ukb-b-11272) (👉 📊)	Total body bone mineral density (age 30-45)	Inverse variance weighted	15	0.62698559	0.296268555	0.034321468
Pineapple (ukb-b-1164) (👉 📊)	Total body bone mineral density (age 30-45)	Weighted median	16	1.075140101	0.531609758	0.043132613
Pineapple (ukb-b-1164) (👉 📊)	Total body bone mineral density (age 30-45)	Inverse variance weighted	16	0.793518599	0.381894678	0.03772348
Naan bread (ukb-b-13281) (👉 📊)	Total body bone mineral density (age 30-45)	Weighted median	17	2.01176155	0.789725631	0.010852325
White rice (ukb-b-14690) (👉 📊)	Total body bone mineral density (age 30-45)	Inverse variance weighted	14	-0.641290407	0.271887792	0.018341134
Savoury biscuits (ukb-b-1503) (👉 📊)	Total body bone mineral density (age 30-45)	MR Egger	33	-3.051304874	1.37379961	0.033785185
Other vegetarian alternative (ukb-b-16150) (👉 📊)	Total body bone mineral density (age 30-45)	MR Egger	30	1.797900049	0.83546388	0.040167849
Scotch pancake (ukb-b-2035) (👉 📊)	Total body bone mineral density (age 30-45)	MR Egger	53	-1.81797374	0.879437363	0.043808278
Green bean (ukb-b-2299) (👉 📊)	Total body bone mineral density (age 30-45)	Inverse variance weighted	16	0.378470195	0.19296733	0.049842
Leek (ukb-b-2530) (👉 📊)	Total body bone mineral density (age 30-45)	MR Egger	13	-1.616965169	0.685624028	0.037921876
Vegetarian sausages/burgers (ukb-b-3383) (👉 📊)	Total body bone mineral density (age 30-45)	Weighted median	35	-1.220033715	0.528415012	0.020951621

Mendelian Randomization Results (Single SNP)

Intake (exposure)	Outcome	SNP	b	se	P-value
Sweets (ukb-b-10217)	Total body bone mineral density (age 30-45)	rs61913309	-2.64049037678426	0.831583008272965	0.0014970347091163
Sweets (ukb-b-10217)	Total body bone mineral density (age 30-45)	rs62559005	-1.43073183192439	0.602034685352928	0.0174780445136364
Sweets (ukb-b-10217)	Total body bone mineral density (age 30-45)	All - Inverse variance weighted	-0.549437675602976	0.199439872415812	0.005870938274333
Omelette (ukb-b-11272)	Total body bone mineral density (age 30-45)	rs12508999	2.54849325237402	1.18668301187467	0.0317473668279387
Omelette (ukb-b-11272)	Total body bone mineral density (age 30-45)	All - Inverse variance weighted	0.626985590374221	0.296268555490787	0.0343214678499475
Pineapple (ukb-b-1164)	Total body bone mineral density (age 30-45)	All - Inverse variance weighted	0.793518599271715	0.381894677570004	0.0377234800874282
Naan bread (ukb-b-13281)	Total body bone mineral density (age 30-45)	rs151165951	-5.25456982458867	2.46702538899357	0.0331781146258253
White rice (ukb-b-14690)	Total body bone mineral density (age 30-45)	rs1927662	-2.2637094312748	0.87750534133686	0.0098883274337987
White rice (ukb-b-14690)	Total body bone mineral density (age 30-45)	All - Inverse variance weighted	-0.641290407035017	0.271887792268202	0.0183411336827101
Savoury biscuits (ukb-b-1503)	Total body bone mineral density (age 30-45)	rs201426	7.68714285486451	3.09399525693717	0.0129720361265495
Savoury biscuits (ukb-b-1503)	Total body bone mineral density (age 30-45)	rs9477316	-8.00916193877474	2.38843305229689	0.0007985055213495
Savoury biscuits (ukb-b-1503)	Total body bone mineral density (age 30-45)	All - MR Egger	-3.05130487442071	1.37379961017815	0.0337851852836073
Other vegetarian alternative (ukb-b-16150)	Total body bone mineral density (age 30-45)	rs4076876	4.011752036999	1.66196709678624	0.0157846266647966
Other vegetarian alternative (ukb-b-16150)	Total body bone mineral density (age 30-45)	All - MR Egger	1.79790004894787	0.835463880425061	0.0401678491066921
Scotch pancake (ukb-b-2035)	Total body bone mineral density (age 30-45)	rs10029250	5.87161218717554	2.56584678911126	0.0221158613870763
Scotch pancake (ukb-b-2035)	Total body bone mineral density (age 30-45)	rs112651842	-8.95527513091252	3.71190660142502	0.0158400198207663
Scotch pancake (ukb-b-2035)	Total body bone mineral density (age 30-45)	rs150204675	-6.40110255047822	3.07739992915338	0.0375222336352972
Scotch pancake (ukb-b-2035)	Total body bone mineral density (age 30-45)	rs17599659	-8.00650497351119	3.33729085811775	0.0164352846677151
Scotch pancake (ukb-b-2035)	Total body bone mineral density (age 30-45)	rs373496	7.41852289648608	2.33339985569764	0.0014764327384364
Scotch pancake (ukb-b-2035)	Total body bone mineral density (age 30-45)	rs62295088	9.1178730952326	2.86527037346857	0.0014615913843589
Scotch pancake (ukb-b-2035)	Total body bone mineral density (age 30-45)	All - MR Egger	-1.81797373991131	0.879437362606078	0.0438082780974791
Green bean (ukb-b-2299)	Total body bone mineral density (age 30-45)	rs115617710	1.71351513204339	0.658960219784543	0.0093133696699927
Green bean (ukb-b-2299)	Total body bone mineral density (age 30-45)	rs79842475	1.92427415247043	0.666578627979952	0.0038919086490846
Green bean (ukb-b-2299)	Total body bone mineral density (age 30-45)	All - Inverse variance weighted	0.37847019497289	0.192967329524237	0.0498420003411211
Leek (ukb-b-2530)	Total body bone mineral density (age 30-45)	rs117166126	-3.20893852150483	1.25567159537146	0.0106018435684866
Leek (ukb-b-2530)	Total body bone mineral density (age 30-45)	rs3862773	2.6743989640223	1.25978266989471	0.0337618110519225
Leek (ukb-b-2530)	Total body bone mineral density (age 30-45)	All - MR Egger	-1.6169651694914	0.685624028408527	0.0379218762816517