Ankylosing spondylitis (ebi-a-GCST005529)

Mendelian Randomization Results

Intake (exposure)	Outcome	Method	Number of SNPs	b	se	P-value
Sweetened cereal (ukb-b-10640) (👉 📊)	Ankylosing spondylitis	Wald ratio	1	-1.630468698	0.50853379	0.001344934
Lamb/mutton (ukb-b-14179) (👉 📊)	Ankylosing spondylitis	Inverse variance weighted	6	-1.419077241	0.72352	0.049838001
Shellfish (ukb-b-143) (👉 📊)	Ankylosing spondylitis	Inverse variance weighted	3	-1.091295015	0.536188143	0.04182233
Non-oily fish (ukb-b-17627) (👉 📊)	Ankylosing spondylitis	Inverse variance weighted	5	0.614515707	0.307035466	0.045344066
Oily fish (ukb-b-2209) (👉 📊)	Ankylosing spondylitis	MR Egger	10	5.155238605	2.098948884	0.03955831
Beef (ukb-b-2862) (👉 📊)	Ankylosing spondylitis	Inverse variance weighted	2	0.696937102	0.355159482	0.049725061
Fresh fruit (ukb-b-3881) (👉 📊)	Ankylosing spondylitis	Weighted median	7	0.637353286	0.299568046	0.033372392
Cooked vegetable (ukb-b-8089) (👉 📊)	Ankylosing spondylitis	Inverse variance weighted	4	-0.912430958	0.378139023	0.015823944
Cauliflower (ukb-b-905) (👉 📊)	Ankylosing spondylitis	Wald ratio	1	0.717557378	0.221768767	0.001213828
Other milk-based pudding (ukb-b-9857) (👉 📊)	Ankylosing spondylitis	Wald ratio	1	1.600678927	0.586437779	0.006343143

Mendelian Randomization Results (Single SNP)

Intake (exposure)	Outcome	SNP	b	se	P-value
Sweetened cereal (ukb-b-10640)	Ankylosing spondylitis	rs7258015	-1.63046869799641	0.508533789855555	0.0013449342833087
Lamb/mutton (ukb-b-14179)	Ankylosing spondylitis	rs224064	-1.56667209647579	0.550172098462305	0.0044049742016061
Lamb/mutton (ukb-b-14179)	Ankylosing spondylitis	rs2726033	-2.07642844949134	0.43549189328174	1.86057206573408e-06
Lamb/mutton (ukb-b-14179)	Ankylosing spondylitis	rs4486004	-4.93170400043257	0.572332325929471	6.88188901410913e-18
Lamb/mutton (ukb-b-14179)	Ankylosing spondylitis	All - Inverse variance weighted	-1.41907724070124	0.723519999857828	0.0498380006884664
Shellfish (ukb-b-143)	Ankylosing spondylitis	rs36102575	-2.08023093925259	0.98271888494726	0.0342758228405128
Shellfish (ukb-b-143)	Ankylosing spondylitis	All - Inverse variance weighted	-1.09129501502988	0.53618814292528	0.0418223301380206
Non-oily fish (ukb-b-17627)	Ankylosing spondylitis	rs1260326	1.2072174293508	0.435312983459534	0.0055505069730618
Non-oily fish (ukb-b-17627)	Ankylosing spondylitis	rs3809717	1.22842720005069	0.461954145589338	0.0078327087370557
Non-oily fish (ukb-b-17627)	Ankylosing spondylitis	All - Inverse variance weighted	0.614515707264794	0.307035465710801	0.045344066201389
Oily fish (ukb-b-2209)	Ankylosing spondylitis	rs1053924	5.14790708831408	0.346690121137009	7.09018780770249e-50
Oily fish (ukb-b-2209)	Ankylosing spondylitis	rs10819087	-1.06461667565786	0.449644348538432	0.0178997151735935
Oily fish (ukb-b-2209)	Ankylosing spondylitis	rs1260326	1.23370316330853	0.444863528032485	0.0055505069730618
Oily fish (ukb-b-2209)	Ankylosing spondylitis	rs16891727	2.60438582806643	0.276349753133788	4.33240043974976e-21
Oily fish (ukb-b-2209)	Ankylosing spondylitis	All - MR Egger	5.15523860504398	2.09894888393894	0.0395583095148408
Beef (ukb-b-2862)	Ankylosing spondylitis	All - Inverse variance weighted	0.696937102285519	0.355159481652455	0.0497250605389007
Cooked vegetable (ukb-b-8089)	Ankylosing spondylitis	rs113993820	-1.87302432204172	0.518072973222333	0.0002999215518362
Cooked vegetable (ukb-b-8089)	Ankylosing spondylitis	All - Inverse variance weighted	-0.912430958272136	0.378139023380406	0.0158239440469472
Cauliflower (ukb-b-905)	Ankylosing spondylitis	rs62179283	0.717557378201867	0.221768766570295	0.0012138283839067
Other milk-based pudding (ukb-b-9857)	Ankylosing spondylitis	rs11716159	1.60067892746648	0.586437779305603	0.0063431430339987