Rheumatoid arthritis (ebi-a-GCST005569)

Mendelian Randomization Results

Intake (exposure)	Outcome	Method	Number of SNPs	b	se	P-value
Sweetened cereal (ukb-b-10640) (👉 📊)	Rheumatoid arthritis	Wald ratio	1	-10.31871963	2.286618851	6.4e-06
Chocolate bar (ukb-b-117) (👉 📊)	Rheumatoid arthritis	Wald ratio	1	-3.363509808	1.30614795	0.010020041
Battered fish (ukb-b-14166) (👉 📊)	Rheumatoid arthritis	Wald ratio	1	5.064677627	2.411638493	0.035720205
Lamb/mutton (ukb-b-14179) (👉 📊)	Rheumatoid arthritis	Weighted median	10	-3.966004922	1.351502096	0.00334068
Lamb/mutton (ukb-b-14179) (👉 📊)	Rheumatoid arthritis	Simple mode	10	-4.488358378	1.940155566	0.04597981
Lamb/mutton (ukb-b-14179) (👉 📊)	Rheumatoid arthritis	Weighted mode	10	-4.57524645	1.825369306	0.03350386
Shellfish (ukb-b-143) (👉 📊)	Rheumatoid arthritis	Weighted median	3	-6.874806942	3.036148704	0.023554547
Shellfish (ukb-b-143) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	3	-6.180988541	2.388533674	0.009659796
Scotch pancake (ukb-b-2035) (👉 📊)	Rheumatoid arthritis	Wald ratio	1	-9.992847685	3.765843828	0.007965042
Seeds (ukb-b-4548) (👉 📊)	Rheumatoid arthritis	Wald ratio	1	6.584815383	2.566579399	0.010299761
Coffee (ukb-b-5237) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	11	1.478513021	0.553591562	0.007567859
Coffee (ukb-b-5237) (👉 📊)	Rheumatoid arthritis	Simple mode	11	3.055773156	1.356127528	0.047909835
Processed meat (ukb-b-6324) (👉 📊)	Rheumatoid arthritis	Weighted median	8	-1.826319566	0.897884092	0.041948977
Poultry (ukb-b-8006) (👉 📊)	Rheumatoid arthritis	Inverse variance weighted	9	1.598164942	0.680583949	0.018863071
Soya dessert (ukb-b-998) (👉 📊)	Rheumatoid arthritis	Wald ratio	1	11.55464644	4.856522318	0.017350177

Mendelian Randomization Results (Single SNP)

Intake (exposure)	Outcome	SNP	b	se	P-value
Sweetened cereal (ukb-b-10640)	Rheumatoid arthritis	rs7258015	-10.3187196299008	2.28661885109499	6.4021427252165e-06
Chocolate bar (ukb-b-117)	Rheumatoid arthritis	rs79174915	-3.3635098077036	1.30614794998449	0.0100200412693424
Battered fish (ukb-b-14166)	Rheumatoid arthritis	rs4143128	5.0646776266829	2.41163849343269	0.0357202048205614
Lamb/mutton (ukb-b-14179)	Rheumatoid arthritis	rs2726033	-5.13136403200958	1.96836346086161	0.0091360979499482
Lamb/mutton (ukb-b-14179)	Rheumatoid arthritis	rs35797675	4.76639200722594	2.17445482866044	0.0283799375665185
Lamb/mutton (ukb-b-14179)	Rheumatoid arthritis	rs3964074	-5.29611404818993	2.29683385087064	0.0211199957211433
Lamb/mutton (ukb-b-14179)	Rheumatoid arthritis	rs416769	-5.75223446917225	2.44706536683239	0.0187398238009454
Lamb/mutton (ukb-b-14179)	Rheumatoid arthritis	rs4449668	18.5844238586378	2.69353134789538	5.21307773279884e-12
Lamb/mutton (ukb-b-14179)	Rheumatoid arthritis	rs4486004	-5.47050208747732	2.53032853177119	0.0306202537333239
Shellfish (ukb-b-143)	Rheumatoid arthritis	rs80356083	-8.84386894093481	4.2654963046499	0.0381396711106441
Shellfish (ukb-b-143)	Rheumatoid arthritis	All - Inverse variance weighted	-6.180988541456	2.38853367383628	0.0096597959449405
Scotch pancake (ukb-b-2035)	Rheumatoid arthritis	rs115373726	-9.99284768467955	3.76584382822845	0.0079650420761466
Seeds (ukb-b-4548)	Rheumatoid arthritis	rs12778642	6.58481538322651	2.56657939875418	0.0102997611042457
Coffee (ukb-b-5237)	Rheumatoid arthritis	rs329122	4.38554046374046	2.16008609257919	0.0423299262474726
Coffee (ukb-b-5237)	Rheumatoid arthritis	All - Inverse variance weighted	1.47851302062152	0.553591562176395	0.0075678587499099
Processed meat (ukb-b-6324)	Rheumatoid arthritis	rs11887120	-3.52589428277644	1.59495406324976	0.0270596888050477
Processed meat (ukb-b-6324)	Rheumatoid arthritis	rs4240672	-2.62222767390377	1.08616772098294	0.0157697412280704
Processed meat (ukb-b-6324)	Rheumatoid arthritis	rs7297175	6.15753861003861	1.81474903474903	0.0006911840916715
Processed meat (ukb-b-6324)	Rheumatoid arthritis	rs871974	-7.16256080483491	2.08534787735849	0.0005931928823447
Poultry (ukb-b-8006)	Rheumatoid arthritis	rs4627402	5.4385376655068	2.04940123819422	0.0079609785658806
Poultry (ukb-b-8006)	Rheumatoid arthritis	All - Inverse variance weighted	1.59816494218691	0.680583949065467	0.0188630707056193
Soya dessert (ukb-b-998)	Rheumatoid arthritis	rs117586700	11.5546464444888	4.85652231756802	0.0173501765913149