ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Osteoarthritis of the hip (hospital diagnosed) (ebi-a-GCST005810)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Salted peanuts (ukb-b-1099) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 14 1.840709039 0.784509406 0.018959891
Other alcohol (ukb-b-12901) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) MR Egger 43 2.876060621 1.33594474 0.037266627
Other alcohol (ukb-b-12901) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Weighted median 43 2.111544121 1.063915774 0.047178855
Other alcohol (ukb-b-12901) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 43 1.944690396 0.77236621 0.011807874
Other alcohol (ukb-b-12901) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Weighted mode 43 5.302702784 2.595382467 0.047347115
Other sweets (ukb-b-139) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Weighted median 26 2.05480113 0.74091374 0.005548517
Lamb/mutton (ukb-b-14179) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 128 -0.801205054 0.37958718 0.034795751
Lobster/crab (ukb-b-14746) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 57 -3.002209455 1.484246271 0.043102383
Dark chocolate (ukb-b-16139) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 21 -1.802656746 0.705231875 0.010584685
Dried fruit (ukb-b-16576) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 156 -0.863992014 0.319756731 0.006891772
Ice-cream (ukb-b-17189) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) MR Egger 16 3.639890608 1.432157348 0.023499517
Powdered/instant soup (ukb-b-19931) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Weighted median 19 2.439726521 1.213049464 0.044300729
Powdered/instant soup (ukb-b-19931) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 19 1.84944542 0.91489116 0.04322883
Tinned tuna (ukb-b-2237) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Weighted median 13 -2.417432561 1.184640635 0.041285994
Indian snacks (ukb-b-282) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) MR Egger 26 3.356903272 1.500765734 0.034853969
Lettuce (ukb-b-2867) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) MR Egger 12 -1.583688852 0.705178627 0.048524482
Green tea (ukb-b-4078) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 130 0.014431646 0.004469268 0.001241872
Bacon (ukb-b-4414) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Weighted median 12 1.940472502 0.59961659 0.001211372
Bacon (ukb-b-4414) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 12 1.833654433 0.425730751 1.65e-05
Dairy smoothie (ukb-b-4955) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) MR Egger 21 2.969992618 1.055486196 0.011083653
Oat crunch (ukb-b-5186) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 12 2.704046773 1.082151446 0.012462543
Fortified wine (ukb-b-9524) (👉 📊) Osteoarthritis of the hip (hospital diagnosed) Inverse variance weighted 22 -2.095980772 0.952837236 0.027826346

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Salted peanuts (ukb-b-1099) Osteoarthritis of the hip (hospital diagnosed) rs7190023 9.03043732388837 2.95586631655166 0.0022499307081682
Salted peanuts (ukb-b-1099) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted 1.84070903924638 0.78450940626922 0.0189598910702683
Other alcohol (ukb-b-12901) Osteoarthritis of the hip (hospital diagnosed) rs1105335 9.76161040865569 3.87715603604833 0.0118115698121939
Other alcohol (ukb-b-12901) Osteoarthritis of the hip (hospital diagnosed) rs115331905 8.58259795801584 3.66888534168599 0.0193202724771307
Other alcohol (ukb-b-12901) Osteoarthritis of the hip (hospital diagnosed) rs117693960 9.59513880537345 4.1484946093265 0.0207270028176362
Other alcohol (ukb-b-12901) Osteoarthritis of the hip (hospital diagnosed) rs148063101 -10.0277236850456 5.01020432021858 0.0453428371365036
Other alcohol (ukb-b-12901) Osteoarthritis of the hip (hospital diagnosed) rs73234113 8.05178894241493 3.98887383353364 0.0435327692122318
Other alcohol (ukb-b-12901) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted 1.94469039589579 0.772366209989144 0.01180787434469
Other alcohol (ukb-b-12901) Osteoarthritis of the hip (hospital diagnosed) All - MR Egger 2.87606062099637 1.3359447396923 0.0372666269309922
Other sweets (ukb-b-139) Osteoarthritis of the hip (hospital diagnosed) rs10732346 5.35804069110072 2.16137585379239 0.0131753023778785
Other sweets (ukb-b-139) Osteoarthritis of the hip (hospital diagnosed) rs117902110 4.99443682620378 2.51348428598504 0.0469160682364896
Lamb/mutton (ukb-b-14179) Osteoarthritis of the hip (hospital diagnosed) rs11090045 -7.17479229306582 3.3507366922378 0.0322532249831191
Lamb/mutton (ukb-b-14179) Osteoarthritis of the hip (hospital diagnosed) rs146908007 -12.2273475764229 4.24012519000169 0.0039300397228531
Lamb/mutton (ukb-b-14179) Osteoarthritis of the hip (hospital diagnosed) rs416769 12.8961553355667 4.27569152240187 0.0025600098209255
Lamb/mutton (ukb-b-14179) Osteoarthritis of the hip (hospital diagnosed) rs62106258 -10.7324876100303 3.7481599970412 0.0041911887352516
Lamb/mutton (ukb-b-14179) Osteoarthritis of the hip (hospital diagnosed) rs62176228 9.47178039874844 4.50952578349924 0.0356942061281174
Lamb/mutton (ukb-b-14179) Osteoarthritis of the hip (hospital diagnosed) rs660880 -8.12345208822087 3.60057703826145 0.0240610612643629
Lamb/mutton (ukb-b-14179) Osteoarthritis of the hip (hospital diagnosed) rs75188715 -9.36599759741547 4.75796876640114 0.0490120803419889
Lamb/mutton (ukb-b-14179) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted -0.80120505366823 0.37958718001606 0.0347957512436399
Lobster/crab (ukb-b-14746) Osteoarthritis of the hip (hospital diagnosed) rs116077835 -29.0243582782573 13.3435996330344 0.0296187230342838
Lobster/crab (ukb-b-14746) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted -3.00220945478376 1.48424627148358 0.0431023825701358
Dark chocolate (ukb-b-16139) Osteoarthritis of the hip (hospital diagnosed) rs145537395 -8.38611956554932 3.40492065269394 0.0137802489602439
Dark chocolate (ukb-b-16139) Osteoarthritis of the hip (hospital diagnosed) rs259386 -6.3634626339097 3.12426269271054 0.0416712312686156
Dark chocolate (ukb-b-16139) Osteoarthritis of the hip (hospital diagnosed) rs7008560 -8.22304465303368 3.28389892425696 0.0122780940252476
Dark chocolate (ukb-b-16139) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted -1.80265674631101 0.705231874943412 0.0105846848581096
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) rs1000214 -12.0464297502476 3.84237920732585 0.0017176708463116
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) rs11586016 -12.9437811418703 3.45908861753886 0.000182588503625
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) rs12708665 -10.5080286758557 4.27656180999897 0.0140055610051444
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) rs12727104 -12.2728035643444 4.07967133571363 0.002627288561973
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) rs1419750 -7.8283761305471 3.76690004118374 0.0376908329810468
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) rs322672 -8.79850181422838 4.21204472130844 0.0367175467848307
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) rs6438468 8.68782938271722 4.11012708065518 0.034535622015067
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) rs72842424 -8.39617836909532 3.87868888055429 0.0304110513766741
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) rs7730004 -11.1355088367372 4.31880815368493 0.0099266082970318
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) rs979678 7.46269421517852 3.55509397361053 0.035803216455398
Dried fruit (ukb-b-16576) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted -0.863992014256183 0.319756730607384 0.0068917715249314
Ice-cream (ukb-b-17189) Osteoarthritis of the hip (hospital diagnosed) rs112107763 4.3444263439609 1.6111838824429 0.007008950545635
Ice-cream (ukb-b-17189) Osteoarthritis of the hip (hospital diagnosed) rs113438694 -4.08187781417176 2.0601033627462 0.0475470314862923
Ice-cream (ukb-b-17189) Osteoarthritis of the hip (hospital diagnosed) rs7251800 4.05644083107498 1.99977115326709 0.0425140847039448
Ice-cream (ukb-b-17189) Osteoarthritis of the hip (hospital diagnosed) All - MR Egger 3.63989060800701 1.43215734817109 0.0234995168651301
Powdered/instant soup (ukb-b-19931) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted 1.84944542006301 0.914891159882479 0.0432288303264876
Indian snacks (ukb-b-282) Osteoarthritis of the hip (hospital diagnosed) rs680086 7.87177972755327 3.9350833872961 0.0454560212754049
Indian snacks (ukb-b-282) Osteoarthritis of the hip (hospital diagnosed) rs76316510 12.7014271701137 3.93304872825742 0.0012404588742473
Indian snacks (ukb-b-282) Osteoarthritis of the hip (hospital diagnosed) All - MR Egger 3.35690327240219 1.50076573413583 0.0348539693855303
Lettuce (ukb-b-2867) Osteoarthritis of the hip (hospital diagnosed) All - MR Egger -1.58368885191174 0.705178626552945 0.0485244822391743
Green tea (ukb-b-4078) Osteoarthritis of the hip (hospital diagnosed) rs114572438 0.128092109610247 0.0550057108335929 0.0198746645935512
Green tea (ukb-b-4078) Osteoarthritis of the hip (hospital diagnosed) rs116888107 0.109318331768652 0.0498588880201597 0.0283394887990615
Green tea (ukb-b-4078) Osteoarthritis of the hip (hospital diagnosed) rs139697284 0.142593366098162 0.0493342285756668 0.0038480869657785
Green tea (ukb-b-4078) Osteoarthritis of the hip (hospital diagnosed) rs142373582 0.100978951616133 0.0480114467722012 0.03544596673682
Green tea (ukb-b-4078) Osteoarthritis of the hip (hospital diagnosed) rs144373542 0.110064644820409 0.0527505737311202 0.0369323727512274
Green tea (ukb-b-4078) Osteoarthritis of the hip (hospital diagnosed) rs150084392 0.110827348724998 0.052340659803069 0.0342239123443197
Green tea (ukb-b-4078) Osteoarthritis of the hip (hospital diagnosed) rs191143834 0.138976329730226 0.0495657898765961 0.0050492316589708
Green tea (ukb-b-4078) Osteoarthritis of the hip (hospital diagnosed) rs2275845 0.138678191440658 0.0537988719394949 0.0099455816296602
Green tea (ukb-b-4078) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted 0.0144316459888855 0.0044692684909492 0.0012418715815288
Bacon (ukb-b-4414) Osteoarthritis of the hip (hospital diagnosed) rs6590783 3.62825497529325 1.35386811821387 0.0073640288838867
Bacon (ukb-b-4414) Osteoarthritis of the hip (hospital diagnosed) rs66799945 4.03109036164958 1.56013058628506 0.0097713910329369
Bacon (ukb-b-4414) Osteoarthritis of the hip (hospital diagnosed) rs74871396 2.74437111221131 1.23470256264318 0.0262361601701733
Bacon (ukb-b-4414) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted 1.83365443280673 0.425730751191811 1.65427254859524e-05
Dairy smoothie (ukb-b-4955) Osteoarthritis of the hip (hospital diagnosed) rs113792963 6.78485175192118 2.74825478224114 0.013557242993482
Dairy smoothie (ukb-b-4955) Osteoarthritis of the hip (hospital diagnosed) rs144950069 6.92347553606424 2.83298931784075 0.0145304064456668
Dairy smoothie (ukb-b-4955) Osteoarthritis of the hip (hospital diagnosed) All - MR Egger 2.96999261788674 1.05548619644894 0.0110836526328141
Oat crunch (ukb-b-5186) Osteoarthritis of the hip (hospital diagnosed) rs12593521 8.65698257606717 3.38662767555289 0.0105814651211597
Oat crunch (ukb-b-5186) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted 2.7040467732085 1.08215144632891 0.012462542501233
Fortified wine (ukb-b-9524) Osteoarthritis of the hip (hospital diagnosed) rs188390104 -10.3225818267061 5.19249787558238 0.0468139040844606
Fortified wine (ukb-b-9524) Osteoarthritis of the hip (hospital diagnosed) rs79482515 -8.8240385286522 4.17460040483004 0.0345370979183439
Fortified wine (ukb-b-9524) Osteoarthritis of the hip (hospital diagnosed) All - Inverse variance weighted -2.09598077207376 0.952837236072077 0.0278263461706788