ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Other vegetarian alternative (ukb-b-16150) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels Inverse variance weighted 28 -3.113053703 1.249292461 0.012707847
Non-oily fish (ukb-b-17627) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels MR Egger 68 -4.115482006 1.385757014 0.004150964
Cheesy biscuits (ukb-b-19847) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels Weighted median 21 3.974842712 2.014721462 0.048507028
Cheesy biscuits (ukb-b-19847) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels Inverse variance weighted 21 3.211839625 1.543819283 0.03748423
Leek (ukb-b-2530) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels Inverse variance weighted 11 2.699558205 0.805063371 0.000798759
Vegetarian sausages/burgers (ukb-b-3383) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels Inverse variance weighted 33 1.811104602 0.892817076 0.04250637
Mushroom (ukb-b-4043) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels Weighted median 10 -1.544906416 0.690091762 0.025175632
Apple (ukb-b-4070) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels Inverse variance weighted 18 0.856166393 0.331135097 0.009722373
Danish pastry (ukb-b-447) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels MR Egger 15 8.648432275 3.464045279 0.026758377
Coffee (ukb-b-5237) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels MR Egger 112 2.062281881 0.932158366 0.029007209
Coffee (ukb-b-5237) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels Weighted median 112 1.233753683 0.61920163 0.04631721
Coffee (ukb-b-5237) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels Weighted mode 112 1.849904518 0.877001084 0.037162159
Blue cheese (ukb-b-7429) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels MR Egger 19 4.132970423 1.845105456 0.038745554
Soya dessert (ukb-b-998) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels MR Egger 27 -6.442022397 2.798443852 0.029943355
Soya dessert (ukb-b-998) (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels Weighted median 27 -3.949545487 1.953627585 0.043212825

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other vegetarian alternative (ukb-b-16150) Osteoclast-associated immunoglobulin-like receptor levels rs145564253 -7.06483093743673 3.38658837821421 0.0369677226508922
Other vegetarian alternative (ukb-b-16150) Osteoclast-associated immunoglobulin-like receptor levels rs4652232 -21.2830098664594 8.34112697257215 0.0107237284656167
Other vegetarian alternative (ukb-b-16150) Osteoclast-associated immunoglobulin-like receptor levels All - Inverse variance weighted -3.1130537030492 1.24929246125981 0.0127078466228882
Non-oily fish (ukb-b-17627) Osteoclast-associated immunoglobulin-like receptor levels rs117418277 -27.4145025078038 13.5045351943031 0.0423543108842276
Non-oily fish (ukb-b-17627) Osteoclast-associated immunoglobulin-like receptor levels rs35287743 -10.8631856641169 3.48634449636699 0.0018336931513118
Non-oily fish (ukb-b-17627) Osteoclast-associated immunoglobulin-like receptor levels rs7791045 13.1576509224895 5.41585453768723 0.0151209563074055
Non-oily fish (ukb-b-17627) Osteoclast-associated immunoglobulin-like receptor levels All - MR Egger -4.11548200628215 1.38575701401581 0.0041509638746005
Cheesy biscuits (ukb-b-19847) Osteoclast-associated immunoglobulin-like receptor levels All - Inverse variance weighted 3.21183962539171 1.54381928291091 0.0374842298310851
Leek (ukb-b-2530) Osteoclast-associated immunoglobulin-like receptor levels rs17111396 11.3309394343559 3.34504975890017 0.0007056474850483
Leek (ukb-b-2530) Osteoclast-associated immunoglobulin-like receptor levels All - Inverse variance weighted 2.69955820468025 0.805063371260892 0.0007987589489043
Vegetarian sausages/burgers (ukb-b-3383) Osteoclast-associated immunoglobulin-like receptor levels rs443804 16.1217415007911 6.35563641104349 0.0111933049474686
Vegetarian sausages/burgers (ukb-b-3383) Osteoclast-associated immunoglobulin-like receptor levels rs797264 15.5835934199229 4.82585555994712 0.0012414238653818
Vegetarian sausages/burgers (ukb-b-3383) Osteoclast-associated immunoglobulin-like receptor levels All - Inverse variance weighted 1.81110460216566 0.8928170760734 0.0425063697912585
Mushroom (ukb-b-4043) Osteoclast-associated immunoglobulin-like receptor levels rs56270010 3.71798528421071 1.77646348611974 0.0363568330896217
Apple (ukb-b-4070) Osteoclast-associated immunoglobulin-like receptor levels All - Inverse variance weighted 0.856166393451241 0.331135097460817 0.0097223734437017
Danish pastry (ukb-b-447) Osteoclast-associated immunoglobulin-like receptor levels All - MR Egger 8.64843227496101 3.46404527913747 0.0267583766797254
Coffee (ukb-b-5237) Osteoclast-associated immunoglobulin-like receptor levels rs10992783 11.8813839933461 5.38120951174012 0.0272485043953995
Coffee (ukb-b-5237) Osteoclast-associated immunoglobulin-like receptor levels rs17144566 8.61032872481247 4.19519414619797 0.0401282061831036
Coffee (ukb-b-5237) Osteoclast-associated immunoglobulin-like receptor levels rs2350804 -9.53423440360607 4.6354761169377 0.0397057353505911
Coffee (ukb-b-5237) Osteoclast-associated immunoglobulin-like receptor levels rs2595223 -10.3532126439906 4.97881593969157 0.0375757536930023
Coffee (ukb-b-5237) Osteoclast-associated immunoglobulin-like receptor levels rs4410790 2.37490018427518 1.03411138411138 0.0216438084839863
Coffee (ukb-b-5237) Osteoclast-associated immunoglobulin-like receptor levels rs57918684 13.3737118202136 4.388580208592 0.0023083863012109
Coffee (ukb-b-5237) Osteoclast-associated immunoglobulin-like receptor levels rs73075167 10.6058304645821 4.17962014205766 0.0111643983261585
Coffee (ukb-b-5237) Osteoclast-associated immunoglobulin-like receptor levels rs9296406 13.1555468455877 5.39775042160255 0.0148003564422564
Coffee (ukb-b-5237) Osteoclast-associated immunoglobulin-like receptor levels All - MR Egger 2.06228188089379 0.932158365687787 0.0290072089198521
Blue cheese (ukb-b-7429) Osteoclast-associated immunoglobulin-like receptor levels rs16934925 4.96867673476844 2.2623542307341 0.0280746470779299
Blue cheese (ukb-b-7429) Osteoclast-associated immunoglobulin-like receptor levels All - MR Egger 4.13297042283227 1.84510545561754 0.0387455542079766
Soya dessert (ukb-b-998) Osteoclast-associated immunoglobulin-like receptor levels rs72835369 29.457310648925 11.7170367190853 0.0119350782124589
Soya dessert (ukb-b-998) Osteoclast-associated immunoglobulin-like receptor levels All - MR Egger -6.44202239723016 2.79844385174039 0.0299433550593511