ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Juvenile rheumatoid arthritis (ebi-a-GCST90018653)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Avocado (ukb-b-12236) (👉 📊) Juvenile rheumatoid arthritis Weighted median 11 5.953693506 2.471976847 0.01601934
Avocado (ukb-b-12236) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 11 4.946688092 1.925222257 0.010187143
Avocado (ukb-b-12236) (👉 📊) Juvenile rheumatoid arthritis Weighted mode 11 6.024038211 2.348188817 0.02811171
Vegetarian alternatives (ukb-b-14425) (👉 📊) Juvenile rheumatoid arthritis Weighted median 5 33.57407251 15.2589544 0.027786569
Vegetarian alternatives (ukb-b-14425) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 5 25.78358981 12.4018338 0.037616036
Savoury biscuits (ukb-b-1503) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 6 -11.14301751 5.379718253 0.038330646
Sprouts (ukb-b-16077) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 6 9.198186121 4.199683864 0.02850907
Salad / raw vegetable (ukb-b-1996) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 90 -4.224194729 2.009721748 0.035563755
Spirits (ukb-b-3751) (👉 📊) Juvenile rheumatoid arthritis MR Egger 7 7.194370452 2.769898262 0.048404881
Spirits (ukb-b-3751) (👉 📊) Juvenile rheumatoid arthritis Weighted median 7 5.414164196 2.021343198 0.007395312
Spirits (ukb-b-3751) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 7 4.613417665 1.780408714 0.009563836
Spirits (ukb-b-3751) (👉 📊) Juvenile rheumatoid arthritis Weighted mode 7 5.115957052 2.0097445 0.043750732
Mushroom (ukb-b-4043) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 5 -6.089919525 3.048133843 0.04572562
Green tea (ukb-b-4078) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 30 0.095265924 0.03127905 0.002321561
Danish pastry (ukb-b-447) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 6 -12.84362802 6.266391976 0.040402997
Turnip/swede (ukb-b-5008) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 7 -4.960590572 2.39380055 0.038240677
Sushi (ukb-b-5213) (👉 📊) Juvenile rheumatoid arthritis Simple mode 20 -17.81523069 6.03553294 0.008190663
Oatcakes (ukb-b-6298) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 6 -4.332724337 1.911718384 0.023426718
Cooked vegetable (ukb-b-8089) (👉 📊) Juvenile rheumatoid arthritis Simple mode 78 10.22792919 4.770297343 0.035181479
Other cereal (ukb-b-8917) (👉 📊) Juvenile rheumatoid arthritis Inverse variance weighted 4 19.6226991 9.548116158 0.03986565
Sweet potato (ukb-b-9686) (👉 📊) Juvenile rheumatoid arthritis Simple mode 8 10.66432289 4.185849092 0.038231285

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Avocado (ukb-b-12236) Juvenile rheumatoid arthritis rs10882792 30.0519955534837 12.3936780578764 0.0153174861100775
Avocado (ukb-b-12236) Juvenile rheumatoid arthritis rs8009320 6.07348651122959 2.17891682658271 0.0053134825723033
Avocado (ukb-b-12236) Juvenile rheumatoid arthritis All - Inverse variance weighted 4.94668809241037 1.9252222565789 0.0101871426038585
Vegetarian alternatives (ukb-b-14425) Juvenile rheumatoid arthritis All - Inverse variance weighted 25.7835898056851 12.4018337962659 0.0376160361487559
Savoury biscuits (ukb-b-1503) Juvenile rheumatoid arthritis rs72703933 -44.2580655134567 19.3140255684892 0.0219345838885025
Savoury biscuits (ukb-b-1503) Juvenile rheumatoid arthritis All - Inverse variance weighted -11.143017505054 5.37971825293376 0.0383306462449795
Sprouts (ukb-b-16077) Juvenile rheumatoid arthritis rs1430633 48.7390048629568 17.8437600283055 0.0063059884356899
Sprouts (ukb-b-16077) Juvenile rheumatoid arthritis rs1475680 18.0104820954945 7.92449886453596 0.0230406615220959
Sprouts (ukb-b-16077) Juvenile rheumatoid arthritis All - Inverse variance weighted 9.19818612081712 4.1996838639775 0.028509070318206
Salad / raw vegetable (ukb-b-1996) Juvenile rheumatoid arthritis rs12517711 -71.1419098912573 28.8530330006054 0.0136759220912283
Salad / raw vegetable (ukb-b-1996) Juvenile rheumatoid arthritis rs2183298 43.634265189288 21.7346165566003 0.0446865534841815
Salad / raw vegetable (ukb-b-1996) Juvenile rheumatoid arthritis rs402360 -63.8523602979008 22.5838672495911 0.0046935886018196
Salad / raw vegetable (ukb-b-1996) Juvenile rheumatoid arthritis rs9323534 -42.3891257771487 20.3915717861575 0.0376396766206317
Salad / raw vegetable (ukb-b-1996) Juvenile rheumatoid arthritis All - Inverse variance weighted -4.22419472947406 2.00972174774119 0.0355637548211765
Spirits (ukb-b-3751) Juvenile rheumatoid arthritis rs62001190 28.5358588591839 12.7726377313562 0.0254738731234992
Spirits (ukb-b-3751) Juvenile rheumatoid arthritis rs74878100 5.77844054413595 1.91566751062095 0.0025578629799688
Spirits (ukb-b-3751) Juvenile rheumatoid arthritis All - Inverse variance weighted 4.61341766491409 1.78040871401143 0.0095638361153882
Spirits (ukb-b-3751) Juvenile rheumatoid arthritis All - MR Egger 7.19437045245789 2.76989826185113 0.048404880865469
Mushroom (ukb-b-4043) Juvenile rheumatoid arthritis rs2410501 -14.0588794394091 5.61292887627118 0.0122544401212512
Mushroom (ukb-b-4043) Juvenile rheumatoid arthritis All - Inverse variance weighted -6.08991952464809 3.04813384267635 0.0457256200675434
Green tea (ukb-b-4078) Juvenile rheumatoid arthritis rs74931176 0.445415810384984 0.12583869936521 0.0004007683014787
Green tea (ukb-b-4078) Juvenile rheumatoid arthritis All - Inverse variance weighted 0.0952659244572829 0.0312790500578682 0.0023215607250954
Danish pastry (ukb-b-447) Juvenile rheumatoid arthritis All - Inverse variance weighted -12.8436280173449 6.26639197604588 0.0404029969269322
Turnip/swede (ukb-b-5008) Juvenile rheumatoid arthritis All - Inverse variance weighted -4.96059057173044 2.39380055004574 0.0382406771303106
Oatcakes (ukb-b-6298) Juvenile rheumatoid arthritis All - Inverse variance weighted -4.33272433666761 1.91171838403909 0.0234267182977112
Cooked vegetable (ukb-b-8089) Juvenile rheumatoid arthritis rs333537 42.3615581319075 18.5385742845361 0.0223099310252037
Cooked vegetable (ukb-b-8089) Juvenile rheumatoid arthritis rs7803655 56.793744784164 19.2841293618755 0.003228473006174
Cooked vegetable (ukb-b-8089) Juvenile rheumatoid arthritis rs9630374 -347.829032281067 173.125970083977 0.0445255217230984
Other cereal (ukb-b-8917) Juvenile rheumatoid arthritis All - Inverse variance weighted 19.6226991004939 9.54811615815732 0.0398656496331976