ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Arthritis (not osteoarthritis) (ebi-a-GCST90038699)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Celery (ukb-b-14145) (👉 📊) Arthritis (not osteoarthritis) Inverse variance weighted 13 0.005653134 0.002688412 0.035485146
Plum (ukb-b-14182) (👉 📊) Arthritis (not osteoarthritis) Weighted median 11 0.00880841 0.00375968 0.019136467
Plum (ukb-b-14182) (👉 📊) Arthritis (not osteoarthritis) Inverse variance weighted 11 0.006573986 0.002917651 0.024247966
White rice (ukb-b-14690) (👉 📊) Arthritis (not osteoarthritis) MR Egger 12 0.020022095 0.00656111 0.012217642
Lobster/crab (ukb-b-14746) (👉 📊) Arthritis (not osteoarthritis) MR Egger 46 0.040901644 0.018132896 0.029115012
Dried fruit (ukb-b-15321) (👉 📊) Arthritis (not osteoarthritis) Weighted median 7 0.015543137 0.006166475 0.011715927
Unsalted peanuts (ukb-b-15555) (👉 📊) Arthritis (not osteoarthritis) MR Egger 38 -0.03529424 0.01218259 0.006371123
Side salad (ukb-b-1604) (👉 📊) Arthritis (not osteoarthritis) MR Egger 15 -0.006184981 0.002862428 0.049965457
Hot chocolate (ukb-b-16449) (👉 📊) Arthritis (not osteoarthritis) Weighted median 18 -0.010727138 0.005107716 0.035712738
Ice-cream (ukb-b-17189) (👉 📊) Arthritis (not osteoarthritis) MR Egger 16 0.01688571 0.006397244 0.01942206
Goat's cheese (ukb-b-20122) (👉 📊) Arthritis (not osteoarthritis) Inverse variance weighted 30 0.012825587 0.006423428 0.045859005
Parsnip (ukb-b-2468) (👉 📊) Arthritis (not osteoarthritis) Inverse variance weighted 15 -0.007219129 0.003666562 0.048963492
Indian snacks (ukb-b-282) (👉 📊) Arthritis (not osteoarthritis) Inverse variance weighted 21 0.01089205 0.00482378 0.023946243
Cabbage/kale (ukb-b-2975) (👉 📊) Arthritis (not osteoarthritis) MR Egger 17 0.009192048 0.004280275 0.048500716
Prune (ukb-b-3022) (👉 📊) Arthritis (not osteoarthritis) Weighted median 14 0.013169575 0.006207808 0.03388367
Other bread (ukb-b-4964) (👉 📊) Arthritis (not osteoarthritis) MR Egger 12 0.018675551 0.007084984 0.024907184
Other bread (ukb-b-4964) (👉 📊) Arthritis (not osteoarthritis) Weighted median 12 0.008774654 0.004359319 0.044130446
Other bread (ukb-b-4964) (👉 📊) Arthritis (not osteoarthritis) Inverse variance weighted 12 0.009896139 0.003747528 0.008273224
Soft cheese (ukb-b-8007) (👉 📊) Arthritis (not osteoarthritis) Inverse variance weighted 15 0.010175935 0.005104922 0.046222323
Spinach (ukb-b-812) (👉 📊) Arthritis (not osteoarthritis) MR Egger 13 -0.020397529 0.006947425 0.013544675
Spinach (ukb-b-812) (👉 📊) Arthritis (not osteoarthritis) Weighted median 13 -0.011646517 0.004959885 0.018867297
Spinach (ukb-b-812) (👉 📊) Arthritis (not osteoarthritis) Inverse variance weighted 13 -0.00748416 0.00348237 0.031621973
Fortified wine (ukb-b-9524) (👉 📊) Arthritis (not osteoarthritis) Weighted median 17 0.018322179 0.007541241 0.015115605
Fortified wine (ukb-b-9524) (👉 📊) Arthritis (not osteoarthritis) Inverse variance weighted 17 0.013449768 0.005741499 0.019152285
Chocolate biscuits (ukb-b-9886) (👉 📊) Arthritis (not osteoarthritis) Inverse variance weighted 9 -0.003883524 0.001794315 0.030437528

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Celery (ukb-b-14145) Arthritis (not osteoarthritis) All - Inverse variance weighted 0.0056531344305569 0.00268841189404 0.0354851460176039
Plum (ukb-b-14182) Arthritis (not osteoarthritis) rs62187193 0.019493488022613 0.0093800203946544 0.0376916327208233
Plum (ukb-b-14182) Arthritis (not osteoarthritis) All - Inverse variance weighted 0.0065739858729219 0.0029176512587625 0.0242479658769143
White rice (ukb-b-14690) Arthritis (not osteoarthritis) All - MR Egger 0.0200220949439907 0.0065611102114057 0.0122176424181332
Lobster/crab (ukb-b-14746) Arthritis (not osteoarthritis) rs186181876 0.118930619168787 0.0577734351145038 0.0395355174103978
Lobster/crab (ukb-b-14746) Arthritis (not osteoarthritis) rs2808659 0.121095001765201 0.0530626239035386 0.0224825607404041
Lobster/crab (ukb-b-14746) Arthritis (not osteoarthritis) rs72784354 -0.134847206104723 0.0602094102753455 0.0251145168408775
Lobster/crab (ukb-b-14746) Arthritis (not osteoarthritis) All - MR Egger 0.0409016438860346 0.0181328962007914 0.0291150119001901
Dried fruit (ukb-b-15321) Arthritis (not osteoarthritis) rs6674704 -0.0223959426541243 0.0113065058106508 0.0476135486158569
Unsalted peanuts (ukb-b-15555) Arthritis (not osteoarthritis) rs56379516 0.0731108618866687 0.0369246020779137 0.0477030729082919
Unsalted peanuts (ukb-b-15555) Arthritis (not osteoarthritis) rs6570675 0.0782369259584293 0.0386067313374523 0.0427125521054096
Unsalted peanuts (ukb-b-15555) Arthritis (not osteoarthritis) rs7496663 -0.0686476523643913 0.034437683137646 0.046219014842649
Unsalted peanuts (ukb-b-15555) Arthritis (not osteoarthritis) All - MR Egger -0.0352942403014738 0.012182589633986 0.0063711231898773
Side salad (ukb-b-1604) Arthritis (not osteoarthritis) All - MR Egger -0.0061849808186642 0.0028624275992172 0.049965457003802
Ice-cream (ukb-b-17189) Arthritis (not osteoarthritis) All - MR Egger 0.0168857097532311 0.0063972440363645 0.0194220600899791
Goat's cheese (ukb-b-20122) Arthritis (not osteoarthritis) rs117552259 0.107408131240264 0.0290823183174207 0.0002214103857295
Goat's cheese (ukb-b-20122) Arthritis (not osteoarthritis) rs402308 0.0756475721548377 0.0342037548536888 0.0269891641940146
Goat's cheese (ukb-b-20122) Arthritis (not osteoarthritis) All - Inverse variance weighted 0.012825586982703 0.0064234282656334 0.0458590045093597
Parsnip (ukb-b-2468) Arthritis (not osteoarthritis) All - Inverse variance weighted -0.0072191287545147 0.0036665621225519 0.0489634919879935
Indian snacks (ukb-b-282) Arthritis (not osteoarthritis) rs148210187 0.0479517982497628 0.0228467868844001 0.0358308219163174
Indian snacks (ukb-b-282) Arthritis (not osteoarthritis) rs4649395 0.0453533624528087 0.0230121195926801 0.0487414008226743
Indian snacks (ukb-b-282) Arthritis (not osteoarthritis) All - Inverse variance weighted 0.0108920500753407 0.0048237799886466 0.0239462428398174
Cabbage/kale (ukb-b-2975) Arthritis (not osteoarthritis) rs758166 0.0186142866560813 0.0073274841973882 0.0110745380662452
Cabbage/kale (ukb-b-2975) Arthritis (not osteoarthritis) All - MR Egger 0.0091920477801974 0.0042802750015296 0.0485007158457678
Prune (ukb-b-3022) Arthritis (not osteoarthritis) rs71427295 -0.0444622723195859 0.0183237073152565 0.0152457168909149
Other bread (ukb-b-4964) Arthritis (not osteoarthritis) rs4794417 0.027804668508557 0.010847253272935 0.010368505481952
Other bread (ukb-b-4964) Arthritis (not osteoarthritis) rs73017061 0.0255264098069645 0.0104626321606806 0.0146966399168662
Other bread (ukb-b-4964) Arthritis (not osteoarthritis) rs74006323 0.0192515651933159 0.0082579420722177 0.019738663933204
Other bread (ukb-b-4964) Arthritis (not osteoarthritis) rs79862891 0.0199593338307988 0.0099220565090309 0.0442607907927856
Other bread (ukb-b-4964) Arthritis (not osteoarthritis) All - Inverse variance weighted 0.0098961391347732 0.0037475281483994 0.0082732236534607
Other bread (ukb-b-4964) Arthritis (not osteoarthritis) All - MR Egger 0.0186755505159038 0.0070849839519279 0.0249071843158637
Soft cheese (ukb-b-8007) Arthritis (not osteoarthritis) rs17713345 0.0415438633084772 0.0165634179833481 0.0121358364345476
Soft cheese (ukb-b-8007) Arthritis (not osteoarthritis) All - Inverse variance weighted 0.0101759345217085 0.0051049221925597 0.0462223231482104
Spinach (ukb-b-812) Arthritis (not osteoarthritis) All - Inverse variance weighted -0.0074841599078534 0.0034823703494402 0.0316219726573939
Spinach (ukb-b-812) Arthritis (not osteoarthritis) All - MR Egger -0.0203975289376906 0.006947424648289 0.013544675342058
Fortified wine (ukb-b-9524) Arthritis (not osteoarthritis) All - Inverse variance weighted 0.0134497678728604 0.0057414985681371 0.0191522851564348
Chocolate biscuits (ukb-b-9886) Arthritis (not osteoarthritis) All - Inverse variance weighted -0.0038835239219114 0.0017943145177642 0.0304375281955333