ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Fracture of pelvis or lower limb (ebi-a-GCST90038706)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Chocolate-covered raisin (ukb-b-1160) (👉 📊) Fracture of pelvis or lower limb Weighted median 46 -0.010686243 0.005140866 0.03764629
Chocolate-covered raisin (ukb-b-1160) (👉 📊) Fracture of pelvis or lower limb Inverse variance weighted 46 -0.00811952 0.003739038 0.029889357
Unsalted nuts (ukb-b-12217) (👉 📊) Fracture of pelvis or lower limb Inverse variance weighted 13 0.009053718 0.004431718 0.041058747
Naan bread (ukb-b-13281) (👉 📊) Fracture of pelvis or lower limb MR Egger 18 0.027514543 0.01295848 0.049677216
Mozzarella (ukb-b-14505) (👉 📊) Fracture of pelvis or lower limb Inverse variance weighted 19 0.017595606 0.007476673 0.018602583
Unsalted peanuts (ukb-b-15555) (👉 📊) Fracture of pelvis or lower limb Weighted median 38 -0.017275217 0.008670538 0.046326715
Unsalted peanuts (ukb-b-15555) (👉 📊) Fracture of pelvis or lower limb Inverse variance weighted 38 -0.01379265 0.006060905 0.022865461
Pea (ukb-b-15945) (👉 📊) Fracture of pelvis or lower limb Weighted median 11 -0.006466294 0.003230527 0.045325383
Pea (ukb-b-15945) (👉 📊) Fracture of pelvis or lower limb Inverse variance weighted 11 -0.006200286 0.002283034 0.006611402
Other savoury snack (ukb-b-18718) (👉 📊) Fracture of pelvis or lower limb Weighted median 18 -0.017559851 0.008272352 0.033777677
Bacon (ukb-b-4414) (👉 📊) Fracture of pelvis or lower limb Inverse variance weighted 12 0.005184062 0.002466603 0.035579504
Pork (ukb-b-5185) (👉 📊) Fracture of pelvis or lower limb Inverse variance weighted 17 -0.008292668 0.004212133 0.048980972
Bread roll (ukb-b-6246) (👉 📊) Fracture of pelvis or lower limb Inverse variance weighted 17 0.004978743 0.002432532 0.040684326
Other egg (ukb-b-8266) (👉 📊) Fracture of pelvis or lower limb MR Egger 15 0.060567566 0.021619365 0.014985417
Soya dessert (ukb-b-998) (👉 📊) Fracture of pelvis or lower limb MR Egger 21 0.055855169 0.019779747 0.010844545

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Chocolate-covered raisin (ukb-b-1160) Fracture of pelvis or lower limb rs4978026 0.0467944339123027 0.0238428416827207 0.0496903646901141
Chocolate-covered raisin (ukb-b-1160) Fracture of pelvis or lower limb All - Inverse variance weighted -0.0081195200146934 0.0037390375167448 0.0298893574571457
Unsalted nuts (ukb-b-12217) Fracture of pelvis or lower limb rs4734720 0.0390587611300687 0.015693385089815 0.0128150600649921
Unsalted nuts (ukb-b-12217) Fracture of pelvis or lower limb rs73913809 0.0308950808880816 0.0156018381571766 0.047678749179437
Unsalted nuts (ukb-b-12217) Fracture of pelvis or lower limb All - Inverse variance weighted 0.0090537181768708 0.0044317183568265 0.0410587471296771
Naan bread (ukb-b-13281) Fracture of pelvis or lower limb All - MR Egger 0.0275145432820045 0.012958479901527 0.0496772155310499
Mozzarella (ukb-b-14505) Fracture of pelvis or lower limb rs116735069 0.0948686368186045 0.0326973642178194 0.0037148104455114
Mozzarella (ukb-b-14505) Fracture of pelvis or lower limb rs12878562 0.0761570337227187 0.0327815840652845 0.0201702820586038
Mozzarella (ukb-b-14505) Fracture of pelvis or lower limb All - Inverse variance weighted 0.0175956055467149 0.0074766726223641 0.0186025826714573
Unsalted peanuts (ukb-b-15555) Fracture of pelvis or lower limb rs117116541 0.0929619270983574 0.033929907733728 0.0061472359413176
Unsalted peanuts (ukb-b-15555) Fracture of pelvis or lower limb All - Inverse variance weighted -0.0137926500457765 0.0060609046668094 0.0228654606458981
Pea (ukb-b-15945) Fracture of pelvis or lower limb rs663060 -0.0176200611234168 0.0072073633580664 0.0144960412040356
Pea (ukb-b-15945) Fracture of pelvis or lower limb All - Inverse variance weighted -0.0062002858265002 0.002283034454312 0.006611402098527
Other savoury snack (ukb-b-18718) Fracture of pelvis or lower limb rs441414 -0.0608570411900505 0.0255924215861554 0.0174100307605047
Bacon (ukb-b-4414) Fracture of pelvis or lower limb rs66626876 0.0204548494782653 0.0088105528678162 0.0202528326875031
Bacon (ukb-b-4414) Fracture of pelvis or lower limb All - Inverse variance weighted 0.0051840619424307 0.0024666033456727 0.0355795035046602
Pork (ukb-b-5185) Fracture of pelvis or lower limb rs11015253 -0.0349211956807453 0.0136384569283664 0.0104523279809973
Pork (ukb-b-5185) Fracture of pelvis or lower limb rs2033773 -0.0386945424887151 0.014429358907654 0.0073259270881259
Pork (ukb-b-5185) Fracture of pelvis or lower limb All - Inverse variance weighted -0.0082926679069465 0.0042121332454273 0.0489809724346838
Bread roll (ukb-b-6246) Fracture of pelvis or lower limb rs153408 0.0216745554379419 0.0069002970237442 0.001683118483138
Bread roll (ukb-b-6246) Fracture of pelvis or lower limb rs35522968 0.017779077535232 0.0086473706166004 0.0397815849349649
Bread roll (ukb-b-6246) Fracture of pelvis or lower limb All - Inverse variance weighted 0.0049787430353506 0.0024325319863134 0.0406843256183402
Other egg (ukb-b-8266) Fracture of pelvis or lower limb rs10865141 -0.0910120232437588 0.0335094347837326 0.0066073545398761
Other egg (ukb-b-8266) Fracture of pelvis or lower limb rs76351643 -0.0640325135084777 0.0311329071175703 0.0397105680160551
Other egg (ukb-b-8266) Fracture of pelvis or lower limb All - MR Egger 0.060567566249527 0.0216193651542921 0.0149854166939893
Soya dessert (ukb-b-998) Fracture of pelvis or lower limb All - MR Egger 0.055855168778552 0.0197797469515882 0.0108445447589659