ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Malignant neoplasm of bone and articular cartilage (finn-b-C3_BONE_CARTILAGE)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Tinned tomato (ukb-b-10565) (👉 📊) Malignant neoplasm of bone and articular cartilage MR Egger 13 11.58055284 4.036710722 0.015274027
Beef (ukb-b-10829) (👉 📊) Malignant neoplasm of bone and articular cartilage Inverse variance weighted 8 5.440189906 2.599897863 0.036397124
Red wine (ukb-b-13556) (👉 📊) Malignant neoplasm of bone and articular cartilage Inverse variance weighted 10 -3.205914299 1.540736331 0.037455179
Fruit smoothie (ukb-b-1780) (👉 📊) Malignant neoplasm of bone and articular cartilage MR Egger 24 10.36765944 4.404330616 0.027917511
White pasta (ukb-b-2512) (👉 📊) Malignant neoplasm of bone and articular cartilage Inverse variance weighted 10 -5.485283469 2.682076918 0.040838828
White pasta (ukb-b-2512) (👉 📊) Malignant neoplasm of bone and articular cartilage Weighted mode 10 -11.90908635 4.799096378 0.034903894
Orange juice (ukb-b-2763) (👉 📊) Malignant neoplasm of bone and articular cartilage Inverse variance weighted 12 -3.681060182 1.799377911 0.040781913
Pure fruit/vegetable juice (ukb-b-337) (👉 📊) Malignant neoplasm of bone and articular cartilage Weighted median 8 -6.411220021 3.08221339 0.0375191
Hard cheese (ukb-b-3542) (👉 📊) Malignant neoplasm of bone and articular cartilage Inverse variance weighted 12 3.464097051 1.569564096 0.027310984
Drinking water (ukb-b-3975) (👉 📊) Malignant neoplasm of bone and articular cartilage MR Egger 24 1.552995915 0.713799189 0.040601318
Green tea (ukb-b-4078) (👉 📊) Malignant neoplasm of bone and articular cartilage Inverse variance weighted 126 -0.030611099 0.014847242 0.039232846
Sliced bread (ukb-b-4566) (👉 📊) Malignant neoplasm of bone and articular cartilage Weighted median 15 2.270485236 1.001130416 0.023333989
Milk chocolate (ukb-b-4569) (👉 📊) Malignant neoplasm of bone and articular cartilage Inverse variance weighted 14 5.175632039 2.26200023 0.022133003
Oat crunch (ukb-b-5186) (👉 📊) Malignant neoplasm of bone and articular cartilage Inverse variance weighted 13 -10.13492489 4.764817879 0.033417341
Lamb (ukb-b-530) (👉 📊) Malignant neoplasm of bone and articular cartilage Weighted median 13 9.807432982 3.462390094 0.004617668
Lamb (ukb-b-530) (👉 📊) Malignant neoplasm of bone and articular cartilage Inverse variance weighted 13 6.569849847 2.808859137 0.019336754
Lamb (ukb-b-530) (👉 📊) Malignant neoplasm of bone and articular cartilage Weighted mode 13 8.184645387 3.69239886 0.046721449
Eggs in sandwiches (ukb-b-5382) (👉 📊) Malignant neoplasm of bone and articular cartilage MR Egger 15 23.74580165 10.05622892 0.034491339
Yorkshire pudding (ukb-b-5605) (👉 📊) Malignant neoplasm of bone and articular cartilage Weighted median 15 -9.568173674 4.212435898 0.023122103
Cucumber (ukb-b-588) (👉 📊) Malignant neoplasm of bone and articular cartilage MR Egger 17 4.926342665 2.20587736 0.041188493
Processed meat (ukb-b-6324) (👉 📊) Malignant neoplasm of bone and articular cartilage Weighted median 125 3.164848435 1.610432793 0.049389233
Instant coffee (ukb-b-930) (👉 📊) Malignant neoplasm of bone and articular cartilage Weighted median 21 1.985837043 0.695271322 0.00428739
Instant coffee (ukb-b-930) (👉 📊) Malignant neoplasm of bone and articular cartilage Inverse variance weighted 21 1.504029884 0.488041556 0.002057765

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Tinned tomato (ukb-b-10565) Malignant neoplasm of bone and articular cartilage rs137930953 14.0984805902768 5.15956924778958 0.0062857238741441
Tinned tomato (ukb-b-10565) Malignant neoplasm of bone and articular cartilage rs58393161 -14.3142701589989 6.78755508927542 0.0349532748729803
Tinned tomato (ukb-b-10565) Malignant neoplasm of bone and articular cartilage All - MR Egger 11.5805528380668 4.03671072204899 0.0152740268552631
Beef (ukb-b-10829) Malignant neoplasm of bone and articular cartilage All - Inverse variance weighted 5.44018990623741 2.59989786276733 0.0363971242717374
Red wine (ukb-b-13556) Malignant neoplasm of bone and articular cartilage All - Inverse variance weighted -3.20591429940966 1.54073633078625 0.0374551794329533
Fruit smoothie (ukb-b-1780) Malignant neoplasm of bone and articular cartilage rs143438158 -28.6695382846684 13.5689623223045 0.034611360786777
Fruit smoothie (ukb-b-1780) Malignant neoplasm of bone and articular cartilage rs6429985 53.4686247337729 24.1208694115568 0.0266439006876879
Fruit smoothie (ukb-b-1780) Malignant neoplasm of bone and articular cartilage rs685117 17.7383725238478 4.92676938112967 0.0003177200629179
Fruit smoothie (ukb-b-1780) Malignant neoplasm of bone and articular cartilage All - MR Egger 10.3676594441441 4.40433061647948 0.0279175112570047
White pasta (ukb-b-2512) Malignant neoplasm of bone and articular cartilage All - Inverse variance weighted -5.48528346930884 2.68207691781916 0.040838827881639
Orange juice (ukb-b-2763) Malignant neoplasm of bone and articular cartilage All - Inverse variance weighted -3.68106018225844 1.79937791081066 0.0407819134424072
Hard cheese (ukb-b-3542) Malignant neoplasm of bone and articular cartilage rs12652998 8.72035146865585 4.10356468147047 0.0335809905251633
Hard cheese (ukb-b-3542) Malignant neoplasm of bone and articular cartilage All - Inverse variance weighted 3.46409705099127 1.56956409556197 0.0273109841179837
Drinking water (ukb-b-3975) Malignant neoplasm of bone and articular cartilage rs28444545 -5.4629965527902 2.47863140946026 0.0275217075667664
Drinking water (ukb-b-3975) Malignant neoplasm of bone and articular cartilage All - MR Egger 1.55299591522072 0.713799188842702 0.04060131752591
Green tea (ukb-b-4078) Malignant neoplasm of bone and articular cartilage rs115172153 0.59147159609543 0.273788800047884 0.0307478561299792
Green tea (ukb-b-4078) Malignant neoplasm of bone and articular cartilage rs117077082 -0.352294915518992 0.159850042956445 0.0275307589213726
Green tea (ukb-b-4078) Malignant neoplasm of bone and articular cartilage rs117914662 0.327482150987629 0.166841039650479 0.0496648486450232
Green tea (ukb-b-4078) Malignant neoplasm of bone and articular cartilage rs138759868 0.552746115112983 0.226561949516794 0.0146989377826063
Green tea (ukb-b-4078) Malignant neoplasm of bone and articular cartilage rs146320720 3.1538472727978 1.35712796442927 0.0201301592042285
Green tea (ukb-b-4078) Malignant neoplasm of bone and articular cartilage rs181929142 0.776901808989652 0.358954103799668 0.0304376060932795
Green tea (ukb-b-4078) Malignant neoplasm of bone and articular cartilage rs186917540 -0.206870872997688 0.0937884058574791 0.0274036775877952
Green tea (ukb-b-4078) Malignant neoplasm of bone and articular cartilage rs62059726 0.641409129571874 0.300645024099802 0.0328883735426863
Green tea (ukb-b-4078) Malignant neoplasm of bone and articular cartilage rs72703007 0.524692083029919 0.225466475613289 0.0199578083405056
Green tea (ukb-b-4078) Malignant neoplasm of bone and articular cartilage All - Inverse variance weighted -0.0306110986284788 0.0148472421807669 0.0392328455848942
Sliced bread (ukb-b-4566) Malignant neoplasm of bone and articular cartilage rs79885987 5.88803292900388 2.35690473002023 0.0124823725036299
Milk chocolate (ukb-b-4569) Malignant neoplasm of bone and articular cartilage All - Inverse variance weighted 5.17563203942 2.26200022987676 0.0221330029169139
Oat crunch (ukb-b-5186) Malignant neoplasm of bone and articular cartilage rs141655467 -33.5205531562577 16.9169146769899 0.0475373040905204
Oat crunch (ukb-b-5186) Malignant neoplasm of bone and articular cartilage All - Inverse variance weighted -10.1349248867577 4.76481787851166 0.0334173410361231
Lamb (ukb-b-530) Malignant neoplasm of bone and articular cartilage rs142252464 9.94084966900786 3.58706090885435 0.005583163216836
Lamb (ukb-b-530) Malignant neoplasm of bone and articular cartilage rs147244930 36.9831933891336 13.7593314614965 0.0071910964831109
Lamb (ukb-b-530) Malignant neoplasm of bone and articular cartilage All - Inverse variance weighted 6.56984984675629 2.80885913742213 0.0193367541765883
Eggs in sandwiches (ukb-b-5382) Malignant neoplasm of bone and articular cartilage rs920644 -62.3459918561367 19.4072106394506 0.0013157741425479
Eggs in sandwiches (ukb-b-5382) Malignant neoplasm of bone and articular cartilage All - MR Egger 23.7458016489481 10.0562289243627 0.0344913385179821
Cucumber (ukb-b-588) Malignant neoplasm of bone and articular cartilage All - MR Egger 4.92634266517383 2.20587735952672 0.0411884929568624
Processed meat (ukb-b-6324) Malignant neoplasm of bone and articular cartilage rs117665299 32.4783554086248 14.954722970638 0.0298723257473595
Processed meat (ukb-b-6324) Malignant neoplasm of bone and articular cartilage rs11887120 26.5923207463572 11.0014127954122 0.0156415701823396
Processed meat (ukb-b-6324) Malignant neoplasm of bone and articular cartilage rs12788387 26.2613242315862 12.5360832228899 0.0361835464351549
Processed meat (ukb-b-6324) Malignant neoplasm of bone and articular cartilage rs6909218 -26.8454515210882 12.1335896203748 0.0269327932862971
Processed meat (ukb-b-6324) Malignant neoplasm of bone and articular cartilage rs77165542 35.5032380322682 14.8707443636986 0.0169654639297537
Processed meat (ukb-b-6324) Malignant neoplasm of bone and articular cartilage rs78553019 -40.0603261381846 17.0421340371383 0.0187399616518592
Instant coffee (ukb-b-930) Malignant neoplasm of bone and articular cartilage rs2726351 4.10222509718198 1.99737603594871 0.0399943648562743
Instant coffee (ukb-b-930) Malignant neoplasm of bone and articular cartilage All - Inverse variance weighted 1.50402988407343 0.488041555892304 0.0020577651537612