ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Grapefruit juice (ukb-b-14351) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Inverse variance weighted 20 -2.212364348 1.037319045 0.032943487
White rice (ukb-b-14690) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Weighted median 14 2.296619214 1.070382665 0.031904445
Water (ukb-b-14898) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) MR Egger 153 2.908910874 1.022154617 0.005045001
Unsalted peanuts (ukb-b-15555) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Inverse variance weighted 45 2.592448203 1.105178985 0.01899001
Fizzy drink (ukb-b-2832) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Weighted median 12 -1.779489395 0.884928778 0.044337678
Latte (ukb-b-3000) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Inverse variance weighted 9 2.403551978 0.952479563 0.011620354
Green tea (ukb-b-4078) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Inverse variance weighted 126 0.010303342 0.005163403 0.045993217
Other cheese (ukb-b-4088) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Inverse variance weighted 17 3.091822056 1.452179941 0.0332468
Danish pastry (ukb-b-447) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Inverse variance weighted 16 3.939902945 1.449322879 0.006558978
Milk chocolate (ukb-b-4569) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Inverse variance weighted 14 2.114762376 0.72589545 0.003576132
Oat crunch (ukb-b-5186) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) MR Egger 13 -7.682516303 3.329796065 0.041502516
Coffee (ukb-b-5237) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) MR Egger 117 -2.00307319 0.854088847 0.020726919
Coffee (ukb-b-5237) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Weighted median 117 -1.471712387 0.71086587 0.038423367
Coffee (ukb-b-5237) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Weighted mode 117 -1.631289094 0.761245339 0.034208725
Lamb (ukb-b-530) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) MR Egger 13 3.327431534 1.365004514 0.032958536
Lamb (ukb-b-530) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Weighted median 13 2.16896277 1.097829861 0.048190797
Courgette (ukb-b-7420) (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) Inverse variance weighted 19 1.456526837 0.646056206 0.0241654

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Grapefruit juice (ukb-b-14351) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - Inverse variance weighted -2.21236434801913 1.03731904547183 0.0329434870232381
White rice (ukb-b-14690) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs114331107 -8.38368212049602 3.52644529441859 0.0174363618366565
White rice (ukb-b-14690) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs143810808 -9.5871170052917 3.92195291914375 0.0145063016957042
Water (ukb-b-14898) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs10440373 -10.0386108606485 5.01398273103442 0.0452714891292401
Water (ukb-b-14898) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs11140831 7.33310720227423 3.36773755875369 0.0294464097392639
Water (ukb-b-14898) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs11167599 -10.8097463468139 4.55258661031341 0.0175766110279095
Water (ukb-b-14898) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs117810762 13.4492580834737 6.10179595256908 0.0275139749688418
Water (ukb-b-14898) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs12981418 -11.075363045859 4.72741498136387 0.0191399086442977
Water (ukb-b-14898) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs1554704 -8.85747429268005 4.39432964353827 0.0438355457201891
Water (ukb-b-14898) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs79079441 7.1913246415672 3.12178187682563 0.0212453254536933
Water (ukb-b-14898) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - MR Egger 2.90891087425178 1.02215461728175 0.0050450014734218
Unsalted peanuts (ukb-b-15555) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs117185125 13.2220469235076 5.96976945391623 0.0267714770902998
Unsalted peanuts (ukb-b-15555) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - Inverse variance weighted 2.59244820316959 1.10517898533331 0.0189900101951255
Fizzy drink (ukb-b-2832) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs6819167 5.03586943421142 2.25330266046921 0.025424983563186
Latte (ukb-b-3000) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs56364544 6.64254958410623 2.95112513744219 0.0243948340461622
Latte (ukb-b-3000) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - Inverse variance weighted 2.40355197756822 0.952479562522355 0.0116203538654802
Green tea (ukb-b-4078) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs12144868 0.102514701910028 0.039573929372252 0.0095847613195077
Green tea (ukb-b-4078) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs138314328 0.196514944582566 0.0968111633084227 0.0423688431026641
Green tea (ukb-b-4078) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs140020799 0.355731779472095 0.150637799095388 0.0182009708875006
Green tea (ukb-b-4078) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs143131281 0.26534951889126 0.114684961554697 0.0206827847457839
Green tea (ukb-b-4078) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs187794144 -0.0867237573751008 0.0436669637930303 0.0470303558013227
Green tea (ukb-b-4078) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs2518524 0.170142973746633 0.0772796539915261 0.0276898366614192
Green tea (ukb-b-4078) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs73215512 0.177291277475002 0.0814664999253781 0.0295367490744184
Green tea (ukb-b-4078) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs74931176 0.31707539845641 0.0954468648673334 0.0008937162873709
Green tea (ukb-b-4078) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs75897995 0.135963262087484 0.0582405178767466 0.0195688618139151
Green tea (ukb-b-4078) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - Inverse variance weighted 0.0103033415102969 0.0051634031661104 0.0459932173905031
Other cheese (ukb-b-4088) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - Inverse variance weighted 3.09182205585805 1.45217994060369 0.0332467998016484
Danish pastry (ukb-b-447) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs71320525 12.1871814560853 5.49186548297432 0.0264776586021242
Danish pastry (ukb-b-447) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs78824754 11.8653774513347 6.03833173015441 0.0494131718033257
Danish pastry (ukb-b-447) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - Inverse variance weighted 3.93990294455427 1.44932287907825 0.006558977665175
Milk chocolate (ukb-b-4569) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs73185404 14.2464888641501 6.38928297480942 0.0257641988388579
Milk chocolate (ukb-b-4569) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - Inverse variance weighted 2.11476237636667 0.725895449765544 0.0035761323010138
Oat crunch (ukb-b-5186) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - MR Egger -7.68251630265334 3.32979606544077 0.0415025158117762
Coffee (ukb-b-5237) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs117810762 -13.319928930674 6.04312058949667 0.0275139749688418
Coffee (ukb-b-5237) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs17842490 13.5891764799649 5.45072539812213 0.0126634943443094
Coffee (ukb-b-5237) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs1942965 9.44584029229316 4.77346269230035 0.0478358783691256
Coffee (ukb-b-5237) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs2372891 14.8827407420125 6.15911549092657 0.0156758513139241
Coffee (ukb-b-5237) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs4615895 -8.39991804958 4.06474083179676 0.0387782497462702
Coffee (ukb-b-5237) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs9398171 8.51008961382245 3.96953314237822 0.0320447866860671
Coffee (ukb-b-5237) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - MR Egger -2.00307318963597 0.854088847071101 0.020726918902427
Lamb (ukb-b-530) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs11687610 -6.94144075009418 3.18817931938999 0.0294624498763925
Lamb (ukb-b-530) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs142252464 2.2567910857919 1.11205889594606 0.0424195087515528
Lamb (ukb-b-530) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - MR Egger 3.32743153415053 1.36500451377914 0.0329585361277479
Courgette (ukb-b-7420) Benign neoplasm of bone and articular cartilage (all cancers excluded) rs114874934 5.84850640991367 2.51159487645613 0.0198801271379981
Courgette (ukb-b-7420) Benign neoplasm of bone and articular cartilage (all cancers excluded) All - Inverse variance weighted 1.45652683663025 0.646056206053306 0.0241653998586151