ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Benign neoplasm: Short bones of lower limb (finn-b-CD2_BENIGN_BONE_SHORT_LOWER)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Bread (ukb-b-11348) (👉 📊) Benign neoplasm: Short bones of lower limb Weighted mode 113 7.779708334 3.618526185 0.033708916
Other fish (ukb-b-1252) (👉 📊) Benign neoplasm: Short bones of lower limb Inverse variance weighted 25 -9.970292142 3.77160356 0.008205003
Plum (ukb-b-14182) (👉 📊) Benign neoplasm: Short bones of lower limb Inverse variance weighted 11 -3.79254981 1.75235586 0.030444571
Savoury biscuits (ukb-b-1503) (👉 📊) Benign neoplasm: Short bones of lower limb Simple mode 32 -25.29484356 12.36159666 0.049293909
Sprouts (ukb-b-16077) (👉 📊) Benign neoplasm: Short bones of lower limb MR Egger 13 -16.21467743 6.027497505 0.021024724
Sprouts (ukb-b-16077) (👉 📊) Benign neoplasm: Short bones of lower limb Inverse variance weighted 13 -7.022359412 3.500937755 0.04487215
Other vegetarian alternative (ukb-b-16150) (👉 📊) Benign neoplasm: Short bones of lower limb Simple mode 29 -23.35637025 10.06649879 0.027838375
Other fruit (ukb-b-18659) (👉 📊) Benign neoplasm: Short bones of lower limb Inverse variance weighted 20 -5.141383003 2.280606368 0.024171456
Tinned tuna (ukb-b-2237) (👉 📊) Benign neoplasm: Short bones of lower limb MR Egger 13 -11.31301516 5.081971043 0.047851257
Indian snacks (ukb-b-282) (👉 📊) Benign neoplasm: Short bones of lower limb MR Egger 24 -10.8740431 4.790929508 0.033373276
Whole egg (ukb-b-4075) (👉 📊) Benign neoplasm: Short bones of lower limb MR Egger 6 -17.33990436 5.737533442 0.039079133
Bacon (ukb-b-4414) (👉 📊) Benign neoplasm: Short bones of lower limb Inverse variance weighted 12 -4.625782103 1.8789079 0.013818295
Danish pastry (ukb-b-447) (👉 📊) Benign neoplasm: Short bones of lower limb Weighted median 16 11.86725905 5.885062377 0.043747172
Danish pastry (ukb-b-447) (👉 📊) Benign neoplasm: Short bones of lower limb Inverse variance weighted 16 9.391518146 4.378959594 0.031977508
Watercress (ukb-b-6181) (👉 📊) Benign neoplasm: Short bones of lower limb Inverse variance weighted 12 -5.943183665 2.754210761 0.030939214
Processed meat (ukb-b-6324) (👉 📊) Benign neoplasm: Short bones of lower limb MR Egger 125 8.064469622 3.808455098 0.036229452
Chocolate sweet (ukb-b-9835) (👉 📊) Benign neoplasm: Short bones of lower limb Inverse variance weighted 20 -2.956326343 1.354517345 0.029067631

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Bread (ukb-b-11348) Benign neoplasm: Short bones of lower limb rs12510662 -33.5089731832353 14.1023142068034 0.0174951587803558
Bread (ukb-b-11348) Benign neoplasm: Short bones of lower limb rs4984685 -20.6111196990777 9.90069856973552 0.0373621685280464
Other fish (ukb-b-1252) Benign neoplasm: Short bones of lower limb rs80082189 -38.7671584406697 18.9671395320569 0.0409622709037103
Other fish (ukb-b-1252) Benign neoplasm: Short bones of lower limb All - Inverse variance weighted -9.97029214192732 3.77160355975704 0.0082050029920954
Plum (ukb-b-14182) Benign neoplasm: Short bones of lower limb rs62187193 -14.2494230459595 6.84294327065853 0.0373102434947492
Plum (ukb-b-14182) Benign neoplasm: Short bones of lower limb All - Inverse variance weighted -3.79254981036368 1.75235586032263 0.0304445707699709
Savoury biscuits (ukb-b-1503) Benign neoplasm: Short bones of lower limb rs201426 89.1357705722775 35.7085328880532 0.0125530505790986
Sprouts (ukb-b-16077) Benign neoplasm: Short bones of lower limb rs115979407 -26.9427409547969 11.3138590687396 0.0172473164252156
Sprouts (ukb-b-16077) Benign neoplasm: Short bones of lower limb rs12025892 -14.7210869624056 7.04793352640269 0.0367338651918844
Sprouts (ukb-b-16077) Benign neoplasm: Short bones of lower limb All - Inverse variance weighted -7.02235941169549 3.50093775469202 0.0448721500530366
Sprouts (ukb-b-16077) Benign neoplasm: Short bones of lower limb All - MR Egger -16.2146774307357 6.02749750462374 0.0210247243564332
Other vegetarian alternative (ukb-b-16150) Benign neoplasm: Short bones of lower limb rs117518847 96.6663499470374 40.5788227179471 0.0172101486054745
Other fruit (ukb-b-18659) Benign neoplasm: Short bones of lower limb rs9902992 -21.7932668813303 9.62304443001453 0.0235313624786751
Other fruit (ukb-b-18659) Benign neoplasm: Short bones of lower limb All - Inverse variance weighted -5.1413830029786 2.28060636759219 0.0241714560417144
Tinned tuna (ukb-b-2237) Benign neoplasm: Short bones of lower limb rs12596114 25.2366976736474 11.7478319985408 0.0316978370929985
Tinned tuna (ukb-b-2237) Benign neoplasm: Short bones of lower limb rs881564 22.6857721535137 10.7328820100631 0.034543451099754
Tinned tuna (ukb-b-2237) Benign neoplasm: Short bones of lower limb All - MR Egger -11.3130151563698 5.08197104287382 0.0478512573444221
Indian snacks (ukb-b-282) Benign neoplasm: Short bones of lower limb rs117616173 51.2019754521025 23.4699611254878 0.0291393556246894
Indian snacks (ukb-b-282) Benign neoplasm: Short bones of lower limb All - MR Egger -10.874043102609 4.790929507981 0.0333732761521617
Whole egg (ukb-b-4075) Benign neoplasm: Short bones of lower limb rs72719958 -11.5578618277924 5.40989154432501 0.0326442720353956
Whole egg (ukb-b-4075) Benign neoplasm: Short bones of lower limb All - MR Egger -17.3399043611109 5.73753344206651 0.0390791333407689
Bacon (ukb-b-4414) Benign neoplasm: Short bones of lower limb All - Inverse variance weighted -4.62578210272182 1.87890790010321 0.013818294533496
Danish pastry (ukb-b-447) Benign neoplasm: Short bones of lower limb All - Inverse variance weighted 9.39151814622283 4.37895959365387 0.0319775076795427
Watercress (ukb-b-6181) Benign neoplasm: Short bones of lower limb All - Inverse variance weighted -5.94318366532007 2.75421076116384 0.0309392143359344
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb rs13134207 -32.0188311304588 12.3997872633798 0.0098170369041889
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb rs2837899 25.9581757190779 13.0540289772322 0.0467543953617072
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb rs62141888 23.0275109858846 10.0775353227896 0.0223108334107173
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb rs62471101 28.7060896087505 12.7129785443837 0.0239447568345432
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb rs7176446 33.2308556883357 13.9915042726567 0.0175454401772008
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb rs73137142 47.0502258836035 21.166622375764 0.0262259183716425
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb rs7412 47.1340787750579 14.8282461972399 0.0014795320613125
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb rs76587391 26.3430669056632 12.0548164861785 0.0288688241776836
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb All - MR Egger 8.06446962190262 3.80845509828783 0.0362294521559283
Chocolate sweet (ukb-b-9835) Benign neoplasm: Short bones of lower limb All - Inverse variance weighted -2.95632634263278 1.35451734484588 0.0290676313948666