ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Benign neoplasm: Short bones of lower limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_LOWER_EXALLC)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Bread (ukb-b-11348) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Weighted mode 113 7.783312729 3.912815056 0.04911864
Other fish (ukb-b-1252) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Inverse variance weighted 25 -9.961459181 3.76360446 0.008126053
Plum (ukb-b-14182) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Inverse variance weighted 11 -3.776261202 1.750013675 0.030939754
Savoury biscuits (ukb-b-1503) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Simple mode 32 -25.00471437 12.04427148 0.046269795
Sprouts (ukb-b-16077) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) MR Egger 13 -16.25436068 6.025976037 0.020753594
Sprouts (ukb-b-16077) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Inverse variance weighted 13 -6.977910328 3.506504438 0.046591988
Other vegetarian alternative (ukb-b-16150) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Simple mode 29 -22.99394994 10.88790785 0.043749022
Other fruit (ukb-b-18659) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Inverse variance weighted 20 -5.091789751 2.292269148 0.026331467
Indian snacks (ukb-b-282) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) MR Egger 24 -10.96035125 4.776604005 0.031668636
Indian snacks (ukb-b-282) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Weighted mode 24 -8.3663683 3.854796914 0.040551735
Whole egg (ukb-b-4075) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) MR Egger 6 -17.21108142 5.723622105 0.039666347
Bacon (ukb-b-4414) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Inverse variance weighted 12 -4.595906798 1.876436764 0.014314472
Danish pastry (ukb-b-447) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Weighted median 16 11.4335449 5.784824922 0.048101336
Danish pastry (ukb-b-447) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Inverse variance weighted 16 9.380640435 4.37236117 0.031917649
Watercress (ukb-b-6181) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Inverse variance weighted 12 -5.904277875 2.751917941 0.031911791
Processed meat (ukb-b-6324) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) MR Egger 125 8.095065847 3.810373269 0.035631486
Chocolate sweet (ukb-b-9835) (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) Inverse variance weighted 20 -2.945429118 1.352176549 0.029384648

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Bread (ukb-b-11348) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs12510662 -33.3385524677452 14.0810116173671 0.0179026804657254
Bread (ukb-b-11348) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs4984685 -20.5743141281864 9.88597634137903 0.0374191190125077
Other fish (ukb-b-1252) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs80082189 -38.5465579571495 18.9626374813728 0.0420764190763515
Other fish (ukb-b-1252) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - Inverse variance weighted -9.96145918130609 3.76360446038891 0.0081260529734675
Plum (ukb-b-14182) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs62187193 -14.1018301518865 6.82952573483371 0.0389388037256262
Plum (ukb-b-14182) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - Inverse variance weighted -3.77626120234968 1.75001367501332 0.0309397540347997
Savoury biscuits (ukb-b-1503) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs201426 88.8965441348854 35.6606876005748 0.0126724379236396
Sprouts (ukb-b-16077) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs115979407 -26.7694862507682 11.3105901120598 0.0179444194032702
Sprouts (ukb-b-16077) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs12025892 -14.7779251360056 7.02086772945029 0.0353037260764767
Sprouts (ukb-b-16077) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - Inverse variance weighted -6.97791032817485 3.50650443836015 0.0465919880529222
Sprouts (ukb-b-16077) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - MR Egger -16.2543606795391 6.02597603680522 0.0207535943274447
Other vegetarian alternative (ukb-b-16150) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs117518847 99.0206325242906 41.2122619764009 0.0162746073580263
Other fruit (ukb-b-18659) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs9902992 -21.6459924622275 9.61969728412583 0.0244379037511494
Other fruit (ukb-b-18659) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - Inverse variance weighted -5.09178975065203 2.29226914831786 0.0263314670559871
Indian snacks (ukb-b-282) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs117616173 51.8823749765874 23.6305048335124 0.0281228947131628
Indian snacks (ukb-b-282) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - MR Egger -10.9603512502486 4.77660400549262 0.0316686361862353
Whole egg (ukb-b-4075) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs72719958 -11.5240197895348 5.40022239053712 0.0328436113769663
Whole egg (ukb-b-4075) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - MR Egger -17.2110814167834 5.72362210520389 0.0396663470396595
Bacon (ukb-b-4414) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - Inverse variance weighted -4.59590679828204 1.87643676446855 0.0143144717295
Danish pastry (ukb-b-447) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - Inverse variance weighted 9.38064043521625 4.37236116954259 0.0319176493432222
Watercress (ukb-b-6181) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - Inverse variance weighted -5.90427787488021 2.75191794132571 0.0319117905543135
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs13134207 -32.2453562353497 12.3702405105679 0.0091422648411698
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs2837899 25.9581757190779 13.0183427307116 0.0461554098173481
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs62141888 22.9726672562368 10.0569689241717 0.0223566323719793
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs62471101 28.5614745477493 12.70640513252 0.0245888600741232
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs7176446 33.2391200145452 13.9584469678187 0.0172520912678097
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs73137142 46.3991496146691 21.0558951191425 0.027551219901579
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs7412 47.5470937846278 14.8635035761056 0.0013794553624909
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb (all cancers excluded) rs76587391 26.4919625012169 12.0490897325033 0.0279014524204945
Processed meat (ukb-b-6324) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - MR Egger 8.09506584709796 3.81037326949247 0.0356314864352596
Chocolate sweet (ukb-b-9835) Benign neoplasm: Short bones of lower limb (all cancers excluded) All - Inverse variance weighted -2.94542911774096 1.35217654946729 0.0293846478832506