ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Muesli (ukb-b-11004) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) MR Egger 10 16.87892615 6.832869171 0.038695091
Flavoured milk (ukb-b-12763) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Inverse variance weighted 20 -5.844158885 2.632481497 0.026417479
Mixed vegetable (ukb-b-13155) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Weighted median 13 -2.751345254 1.3520942 0.041863261
Other sweets (ukb-b-139) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Inverse variance weighted 26 -3.533792477 1.330107363 0.00788927
Water (ukb-b-14898) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) MR Egger 153 9.045198694 2.505701436 0.000416188
Boiled/baked potatoes (ukb-b-18007) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Weighted median 9 -2.353033909 1.145017567 0.039877081
Boiled/baked potatoes (ukb-b-18007) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Inverse variance weighted 9 -2.212950924 0.879672853 0.011881237
Grapefruit (ukb-b-18758) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Weighted median 16 14.33870281 4.406657156 0.001138432
Grapefruit (ukb-b-18758) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Inverse variance weighted 16 10.70778017 3.144000549 0.000659749
Grapefruit (ukb-b-18758) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Simple mode 16 16.51244076 7.716266097 0.04920232
Grapefruit (ukb-b-18758) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Weighted mode 16 16.01462963 6.336346906 0.023213081
Quorn (ukb-b-19069) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) MR Egger 25 9.535185548 4.533164891 0.046568882
Cabbage/kale (ukb-b-2975) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Weighted median 20 3.221825533 1.529726197 0.035191739
Cabbage/kale (ukb-b-2975) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Inverse variance weighted 20 3.107825584 1.055127921 0.003224862
Sweet biscuits (ukb-b-3646) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Inverse variance weighted 11 -1.414882025 0.701006478 0.043553991
Beer/cider (ukb-b-4961) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) MR Egger 14 5.989125988 2.463019016 0.03163874
Fresh tomato (ukb-b-730) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Inverse variance weighted 10 1.905522026 0.868438147 0.028221445
Filtered coffee (ukb-b-748) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Weighted median 21 -1.995031128 0.92540648 0.031095923
Filtered coffee (ukb-b-748) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Inverse variance weighted 21 -1.569836025 0.649499226 0.015649256
Other meat (ukb-b-770) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Inverse variance weighted 25 8.485754484 3.778456232 0.024715168
Other cereal (ukb-b-8917) (👉 📊) Benign neoplasm: Short bones of upper limb (all cancers excluded) Simple mode 14 -17.72181488 7.8589114 0.042017939

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Muesli (ukb-b-11004) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs72751802 14.2058297018245 5.50150986384102 0.0098181416653726
Muesli (ukb-b-11004) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - MR Egger 16.8789261490793 6.83286917051993 0.0386950908687997
Flavoured milk (ukb-b-12763) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs77166451 -36.149823471636 16.070717528072 0.0244856684875972
Flavoured milk (ukb-b-12763) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - Inverse variance weighted -5.84415888488349 2.63248149703954 0.0264174793287517
Other sweets (ukb-b-139) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs10732346 -17.7469799057109 6.75760561238321 0.008633820957822
Other sweets (ukb-b-139) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - Inverse variance weighted -3.53379247719819 1.33010736322737 0.0078892695341363
Water (ukb-b-14898) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs117810762 30.4189993617015 14.7511620125241 0.0391941630529742
Water (ukb-b-14898) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs11961595 -29.2409437655569 12.4153180657478 0.0185111870988005
Water (ukb-b-14898) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs13171354 20.4669815732859 9.27766345524273 0.0273805585783936
Water (ukb-b-14898) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs1873276 -24.1246894059182 11.9268127400045 0.043101273458614
Water (ukb-b-14898) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs2716991 -25.8790226785992 11.2222642722919 0.0211082361861039
Water (ukb-b-14898) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs34533294 63.5470762751367 23.0898312613448 0.0059202285648082
Water (ukb-b-14898) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs6541139 -21.8151032181215 10.7401974778748 0.0422383538831786
Water (ukb-b-14898) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs7626335 29.3530444149356 10.2053134489131 0.0040242938882587
Water (ukb-b-14898) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs780093 -29.1011776192375 11.2259423426343 0.0095332466060593
Water (ukb-b-14898) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - MR Egger 9.04519869351937 2.50570143616759 0.0004161881831542
Boiled/baked potatoes (ukb-b-18007) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs117282450 -4.40623089442096 1.9409115567764 0.0231962797354933
Boiled/baked potatoes (ukb-b-18007) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - Inverse variance weighted -2.21295092382037 0.879672852909895 0.0118812374272459
Grapefruit (ukb-b-18758) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs75128811 18.7067376256565 8.09767296253783 0.0208805452791679
Grapefruit (ukb-b-18758) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - Inverse variance weighted 10.7077801681237 3.14400054913136 0.0006597486150103
Quorn (ukb-b-19069) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs117321945 46.3506711409396 18.465697240865 0.0120698374162943
Quorn (ukb-b-19069) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs12824603 -33.38433201628 15.2624699206797 0.0287171341233328
Quorn (ukb-b-19069) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs144224609 28.4538181720107 9.14298043631435 0.001857650897797
Quorn (ukb-b-19069) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - MR Egger 9.53518554758146 4.53316489059499 0.0465688820131896
Cabbage/kale (ukb-b-2975) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs118053517 12.1961971375672 5.12730086891782 0.0173748518822025
Cabbage/kale (ukb-b-2975) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs138929729 12.4961715160796 5.87334474371678 0.0333696513314726
Cabbage/kale (ukb-b-2975) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs617579 10.3783819872148 4.99724600670973 0.037818147212221
Cabbage/kale (ukb-b-2975) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - Inverse variance weighted 3.10782558377564 1.05512792110719 0.0032248620471406
Sweet biscuits (ukb-b-3646) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs60129519 -5.40778325479373 2.25856603955504 0.0166501404908345
Sweet biscuits (ukb-b-3646) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - Inverse variance weighted -1.41488202508962 0.701006477791325 0.0435539913194534
Beer/cider (ukb-b-4961) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - MR Egger 5.98912598808065 2.46301901622308 0.0316387399062866
Fresh tomato (ukb-b-730) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs114826856 7.75860259074972 3.11036929730638 0.0126159138568568
Fresh tomato (ukb-b-730) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs12607299 5.20229473145318 2.64757401914284 0.049422466124017
Fresh tomato (ukb-b-730) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - Inverse variance weighted 1.90552202644186 0.868438146886953 0.0282214446236512
Filtered coffee (ukb-b-748) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs78169764 -5.81477285904149 1.98285627636896 0.003362193499288
Filtered coffee (ukb-b-748) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - Inverse variance weighted -1.56983602478829 0.649499225942394 0.0156492557066179
Other meat (ukb-b-770) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs71571162 69.7953569250334 20.2729006890645 0.0005757443999704
Other meat (ukb-b-770) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs75788396 47.8438197704059 20.2433064360178 0.0181062075122196
Other meat (ukb-b-770) Benign neoplasm: Short bones of upper limb (all cancers excluded) All - Inverse variance weighted 8.48575448440013 3.77845623193857 0.0247151681592301
Other cereal (ukb-b-8917) Benign neoplasm: Short bones of upper limb (all cancers excluded) rs11710714 56.8371227818143 18.1000267057123 0.0016885103331352