ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Tinned tomato (ukb-b-10565) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) Weighted median 13 -3.356695952 1.638108827 0.040449523
Double crust pastry (ukb-b-1255) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) Inverse variance weighted 10 4.496923122 2.224363332 0.04321071
Snackpot (ukb-b-12912) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) MR Egger 116 21.76020078 9.725442357 0.02720084
Mashed potato (ukb-b-15710) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) Inverse variance weighted 11 -2.665094989 1.29529513 0.039636281
Other savoury snack (ukb-b-18718) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) MR Egger 24 -8.97199859 4.108030667 0.039907248
Oily fish (ukb-b-2209) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) MR Egger 168 5.304805226 2.634699926 0.045684173
Cherry (ukb-b-2221) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) Inverse variance weighted 17 5.389400041 2.649004518 0.041901195
Fizzy drink (ukb-b-2832) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) Inverse variance weighted 12 -3.029637462 1.31431438 0.021160489
Other vegetables (ukb-b-3055) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) MR Egger 14 6.72385509 3.060586181 0.048403751
Vegetarian sausages/burgers (ukb-b-3383) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) MR Egger 34 -8.385713498 3.465770879 0.021396865
Spirits (ukb-b-3751) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) Weighted median 25 3.12725587 1.204589506 0.009428382
Spirits (ukb-b-3751) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) Inverse variance weighted 25 2.0682251 0.937578903 0.027389523
Ham (ukb-b-4442) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) Weighted median 9 3.487279422 1.282502449 0.006545565
Ham (ukb-b-4442) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) Inverse variance weighted 9 2.302815736 1.021437491 0.024165659
Breaded fish (ukb-b-5753) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) MR Egger 20 -12.62475684 4.935586949 0.019770197
Yogurt (ukb-b-7753) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) MR Egger 9 -10.35839508 3.879658281 0.032003187
Poultry (ukb-b-8006) (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) Inverse variance weighted 80 2.459254289 1.068551 0.021364222

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Double crust pastry (ukb-b-1255) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs116893288 13.1764689191394 6.45522838030517 0.0412300782670336
Double crust pastry (ukb-b-1255) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - Inverse variance weighted 4.49692312181453 2.22436333158088 0.0432107104885112
Snackpot (ukb-b-12912) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs11663173 129.267043551914 56.3062619418126 0.0216882059849171
Snackpot (ukb-b-12912) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs117983125 116.199007744201 44.382814974042 0.0088418787825608
Snackpot (ukb-b-12912) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs140930672 -70.0293327316363 34.0403273778999 0.0396625535459368
Snackpot (ukb-b-12912) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs187579178 84.4907851699677 40.915089606826 0.0389203984401077
Snackpot (ukb-b-12912) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs187693471 82.4055617677087 31.7370800719529 0.0094176889970495
Snackpot (ukb-b-12912) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs73035011 93.5931899641577 37.959229390681 0.0136774794949662
Snackpot (ukb-b-12912) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - MR Egger 21.7602007756138 9.72544235650291 0.027200839606012
Mashed potato (ukb-b-15710) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs264633 -7.1400708336269 2.98147362126177 0.0166288582387832
Mashed potato (ukb-b-15710) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - Inverse variance weighted -2.66509498901888 1.29529512985423 0.0396362810745518
Other savoury snack (ukb-b-18718) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs113182762 -47.3917638294555 22.7170353943972 0.0369625646141042
Other savoury snack (ukb-b-18718) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs441414 26.9566575827533 12.3413931367274 0.0289440634222233
Other savoury snack (ukb-b-18718) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - MR Egger -8.9719985896237 4.10803066658776 0.039907248136192
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs12855717 -15.756594547744 7.27730625194198 0.0303747806852322
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs13023088 -16.9513932752618 7.91750517796025 0.0322738884460743
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs16850013 -26.0064830623809 11.7701399714613 0.0271377645278644
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs17050031 18.6153437572619 7.35318527371112 0.0113542558773998
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs17756423 18.7997928475656 9.52759312991721 0.0484734249726765
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs1925517 -18.3840443093355 8.52449552125712 0.0310357717665751
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs2271308 16.8919201290506 8.36655717426009 0.0434891923713205
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs4419275 -18.7255229960837 9.30864148938264 0.0442591753504575
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs4817505 20.3492613382683 9.76325746148724 0.0371356452222684
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs552234 -15.3854079021928 7.52957741641911 0.0410198280044618
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs6059844 -21.2452614067145 8.09083553785875 0.0086434751804865
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs7243428 -23.2617271774641 8.36774949146274 0.005437123075047
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs77424805 -20.1947625822089 8.04245881772502 0.0120383400442192
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs7965154 18.9572554934041 9.26862793761097 0.0408239005969589
Oily fish (ukb-b-2209) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - MR Egger 5.30480522611819 2.63469992572272 0.0456841730170671
Cherry (ukb-b-2221) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs118161273 35.9097794984009 17.4448746002357 0.0395448816397848
Cherry (ukb-b-2221) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs6676180 17.5000239332931 8.68299874589544 0.0438590377533842
Cherry (ukb-b-2221) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - Inverse variance weighted 5.38940004120742 2.64900451839168 0.0419011953489874
Fizzy drink (ukb-b-2832) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs6819167 -11.4027595097233 4.74765630322118 0.0163161415990813
Fizzy drink (ukb-b-2832) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - Inverse variance weighted -3.02963746171979 1.31431438027413 0.0211604885339056
Other vegetables (ukb-b-3055) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - MR Egger 6.72385509046928 3.06058618142025 0.0484037505500221
Vegetarian sausages/burgers (ukb-b-3383) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs112014270 -30.7218101141483 14.1499847576466 0.0299194578973066
Vegetarian sausages/burgers (ukb-b-3383) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs565594 33.6906450590162 15.0077507133618 0.0247756419330495
Vegetarian sausages/burgers (ukb-b-3383) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs75172571 -26.3599367749401 10.531045249878 0.0123121410025945
Vegetarian sausages/burgers (ukb-b-3383) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - MR Egger -8.38571349847575 3.46577087909207 0.0213968654254841
Spirits (ukb-b-3751) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs139164359 11.0156971375808 3.98522622345337 0.0057074190634366
Spirits (ukb-b-3751) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs78876987 -9.496875 4.54375 0.0366091512363853
Spirits (ukb-b-3751) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - Inverse variance weighted 2.06822509960602 0.937578902983881 0.0273895234831636
Ham (ukb-b-4442) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs140758254 3.7888169175081 1.73048834698673 0.0285641822152264
Ham (ukb-b-4442) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - Inverse variance weighted 2.30281573635442 1.0214374908118 0.0241656588230594
Breaded fish (ukb-b-5753) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs10811184 22.3110066267478 9.63499643679197 0.0205789341081058
Breaded fish (ukb-b-5753) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - MR Egger -12.6247568431366 4.93558694894302 0.0197701966226238
Yogurt (ukb-b-7753) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs149870452 -9.84057383934931 4.34667433544946 0.0235783155757198
Yogurt (ukb-b-7753) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - MR Egger -10.3583950778708 3.87965828097048 0.0320031874486725
Poultry (ukb-b-8006) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs4547132 26.3964245800641 9.34302817339059 0.0047243198715907
Poultry (ukb-b-8006) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) rs72904998 20.6342956778864 9.42524487155794 0.0285780705100738
Poultry (ukb-b-8006) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) All - Inverse variance weighted 2.45925428861505 1.06855100000322 0.0213642222248578