ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sweets (ukb-b-10217) (👉 📊) Other acquired deformities of ankle and foot MR Egger 21 -6.145958134 2.430735339 0.020473278
Other fish (ukb-b-1252) (👉 📊) Other acquired deformities of ankle and foot Inverse variance weighted 25 13.35341081 4.616517097 0.003821536
Sweetcorn (ukb-b-13567) (👉 📊) Other acquired deformities of ankle and foot MR Egger 20 9.858138591 4.597855374 0.045931503
Mashed potato (ukb-b-15710) (👉 📊) Other acquired deformities of ankle and foot Inverse variance weighted 11 -5.857901928 2.094719561 0.005165799
Low fat hard cheese (ukb-b-18079) (👉 📊) Other acquired deformities of ankle and foot Inverse variance weighted 16 6.778939023 3.002321034 0.023951929
Cheesecake (ukb-b-1814) (👉 📊) Other acquired deformities of ankle and foot Simple mode 26 -20.34118287 9.48792003 0.0419551
Low calorie drink (ukb-b-19703) (👉 📊) Other acquired deformities of ankle and foot Inverse variance weighted 19 -2.589143802 1.150484448 0.024418406
Scotch pancake (ukb-b-2035) (👉 📊) Other acquired deformities of ankle and foot Weighted median 53 -10.68577071 5.196023109 0.039731582
Baguette (ukb-b-5277) (👉 📊) Other acquired deformities of ankle and foot MR Egger 13 -11.09515486 3.790831455 0.013768027
Banana (ukb-b-5362) (👉 📊) Other acquired deformities of ankle and foot MR Egger 16 -6.884213232 3.039414347 0.039909529
Peach/nectarine (ukb-b-6154) (👉 📊) Other acquired deformities of ankle and foot MR Egger 17 12.4951463 5.537789804 0.039404842
Bread roll (ukb-b-6246) (👉 📊) Other acquired deformities of ankle and foot MR Egger 18 -5.963442731 2.782946912 0.047845645
Pancake (ukb-b-6500) (👉 📊) Other acquired deformities of ankle and foot Simple mode 45 -20.58617134 9.288846586 0.031893691
Crumble (ukb-b-7641) (👉 📊) Other acquired deformities of ankle and foot MR Egger 24 -12.47794706 5.379907388 0.030050874
Spinach (ukb-b-812) (👉 📊) Other acquired deformities of ankle and foot Weighted median 14 -8.817412642 3.54994837 0.012998356
Spinach (ukb-b-812) (👉 📊) Other acquired deformities of ankle and foot Simple mode 14 -9.861972673 4.456354342 0.045398623
Spinach (ukb-b-812) (👉 📊) Other acquired deformities of ankle and foot Weighted mode 14 -10.10555472 4.29924737 0.035190612
Other milk-based pudding (ukb-b-9857) (👉 📊) Other acquired deformities of ankle and foot Weighted median 22 13.49672139 5.643131198 0.016770184

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sweets (ukb-b-10217) Other acquired deformities of ankle and foot rs111664160 -7.02169435754559 3.12475606607382 0.024632512292983
Sweets (ukb-b-10217) Other acquired deformities of ankle and foot All - MR Egger -6.14595813406668 2.43073533865395 0.0204732775942045
Other fish (ukb-b-1252) Other acquired deformities of ankle and foot rs61993987 78.9226752882373 33.7593020987207 0.0193973506824119
Other fish (ukb-b-1252) Other acquired deformities of ankle and foot rs7235226 31.0963198478613 15.5555885717682 0.0456034970548046
Other fish (ukb-b-1252) Other acquired deformities of ankle and foot rs72838067 106.679333078246 35.4043795877259 0.0025853600554169
Other fish (ukb-b-1252) Other acquired deformities of ankle and foot All - Inverse variance weighted 13.3534108089703 4.61651709736745 0.0038215357774462
Sweetcorn (ukb-b-13567) Other acquired deformities of ankle and foot rs116917456 16.739539625897 7.95753107721266 0.0354125064200652
Sweetcorn (ukb-b-13567) Other acquired deformities of ankle and foot rs149477690 32.7952913034549 13.3500898315352 0.0140274532768006
Sweetcorn (ukb-b-13567) Other acquired deformities of ankle and foot All - MR Egger 9.85813859080943 4.59785537387999 0.0459315034965353
Mashed potato (ukb-b-15710) Other acquired deformities of ankle and foot rs57664184 -18.5285971723329 6.86658684372846 0.0069679787573132
Mashed potato (ukb-b-15710) Other acquired deformities of ankle and foot All - Inverse variance weighted -5.85790192816334 2.09471956102957 0.0051657985672253
Low fat hard cheese (ukb-b-18079) Other acquired deformities of ankle and foot rs7915755 33.0448585863211 11.7755696994673 0.0050126199653841
Low fat hard cheese (ukb-b-18079) Other acquired deformities of ankle and foot All - Inverse variance weighted 6.7789390234305 3.00232103363095 0.023951928659094
Cheesecake (ukb-b-1814) Other acquired deformities of ankle and foot rs650058 47.8005487554967 18.1304280552724 0.0083770623584511
Low calorie drink (ukb-b-19703) Other acquired deformities of ankle and foot rs890797 -13.0773271861872 6.18287174099056 0.0344223187688616
Low calorie drink (ukb-b-19703) Other acquired deformities of ankle and foot All - Inverse variance weighted -2.58914380212992 1.15048444762756 0.0244184055775647
Scotch pancake (ukb-b-2035) Other acquired deformities of ankle and foot rs112118594 39.0975974998372 17.9745705170538 0.0296180005867602
Scotch pancake (ukb-b-2035) Other acquired deformities of ankle and foot rs138194402 147.049909282271 59.6453497303379 0.0136858680418741
Scotch pancake (ukb-b-2035) Other acquired deformities of ankle and foot rs189587401 -29.1658542061818 12.5237090741496 0.0198669528923527
Baguette (ukb-b-5277) Other acquired deformities of ankle and foot rs73101535 -7.24205286698593 3.34689943236586 0.0304789709168638
Baguette (ukb-b-5277) Other acquired deformities of ankle and foot All - MR Egger -11.0951548625091 3.79083145543826 0.0137680268815522
Banana (ukb-b-5362) Other acquired deformities of ankle and foot rs4841580 11.1402078401247 5.03751003075623 0.0270046043932439
Banana (ukb-b-5362) Other acquired deformities of ankle and foot All - MR Egger -6.88421323197422 3.03941434694657 0.0399095290093779
Peach/nectarine (ukb-b-6154) Other acquired deformities of ankle and foot rs78476393 15.7333714989764 6.30977641985526 0.0126493746775286
Peach/nectarine (ukb-b-6154) Other acquired deformities of ankle and foot All - MR Egger 12.4951463006581 5.53778980366543 0.0394048415628159
Bread roll (ukb-b-6246) Other acquired deformities of ankle and foot rs2103867 -15.3141407378696 6.95349847892221 0.0276395456587421
Bread roll (ukb-b-6246) Other acquired deformities of ankle and foot All - MR Egger -5.96344273067293 2.78294691181231 0.0478456445019418
Pancake (ukb-b-6500) Other acquired deformities of ankle and foot rs12959805 44.1292356185973 18.7364820683064 0.0185098854969786
Pancake (ukb-b-6500) Other acquired deformities of ankle and foot rs142571999 32.8421188255947 15.1777230194392 0.0304768604791876
Crumble (ukb-b-7641) Other acquired deformities of ankle and foot rs114316275 59.8011942519978 30.3479986533657 0.0487793485965224
Crumble (ukb-b-7641) Other acquired deformities of ankle and foot rs116756799 102.568155685356 46.3532597194992 0.0269149155605987
Crumble (ukb-b-7641) Other acquired deformities of ankle and foot All - MR Egger -12.477947060908 5.37990738752214 0.0300508741464425
Spinach (ukb-b-812) Other acquired deformities of ankle and foot rs111686396 21.6403720993628 8.15892595495281 0.0079932334328343
Spinach (ukb-b-812) Other acquired deformities of ankle and foot rs117367361 -13.758758777829 5.9858792688921 0.0215313034037473
Other milk-based pudding (ukb-b-9857) Other acquired deformities of ankle and foot rs137977536 78.4771578791394 29.7680787684007 0.0083819146486628
Other milk-based pudding (ukb-b-9857) Other acquired deformities of ankle and foot rs76632750 29.9036304499257 13.8712915274875 0.0310998476770275
Other milk-based pudding (ukb-b-9857) Other acquired deformities of ankle and foot rs77851248 22.9100809689012 10.467000654743 0.0286120054257102