ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Satsuma (ukb-b-11563) (👉 📊) Ankylosis of joint Weighted median 18 4.521755759 2.275141239 0.046871272
Other sweets (ukb-b-139) (👉 📊) Ankylosis of joint Inverse variance weighted 26 3.894895334 1.959123612 0.046802794
Shellfish (ukb-b-143) (👉 📊) Ankylosis of joint Weighted median 40 -14.40650446 6.382270128 0.023991232
Shellfish (ukb-b-143) (👉 📊) Ankylosis of joint Inverse variance weighted 40 -10.59295849 4.508699959 0.018801243
Cereal (ukb-b-15926) (👉 📊) Ankylosis of joint Weighted median 175 -4.103400645 1.755693627 0.01942898
Rose wine (ukb-b-16124) (👉 📊) Ankylosis of joint MR Egger 14 11.20584428 5.107897912 0.048672773
Rose wine (ukb-b-16124) (👉 📊) Ankylosis of joint Inverse variance weighted 14 5.960371338 2.602468109 0.022005298
Carrot (ukb-b-16710) (👉 📊) Ankylosis of joint Weighted median 5 5.697435113 2.662121374 0.032339732
Carrot (ukb-b-16710) (👉 📊) Ankylosis of joint Inverse variance weighted 5 6.236309595 2.036198809 0.002193342
Fruit smoothie (ukb-b-1780) (👉 📊) Ankylosis of joint MR Egger 24 -11.69163728 4.211278137 0.011012554
Espresso (ukb-b-19142) (👉 📊) Ankylosis of joint MR Egger 33 7.671245346 3.291148344 0.026438753
Bran cereal (ukb-b-19498) (👉 📊) Ankylosis of joint Inverse variance weighted 4 -6.947037782 3.403206563 0.041218909
Cheesy biscuits (ukb-b-19847) (👉 📊) Ankylosis of joint Inverse variance weighted 24 10.83372775 4.359763606 0.012957521
Green tea (ukb-b-4078) (👉 📊) Ankylosis of joint MR Egger 126 0.069389942 0.031663074 0.030283264
Green tea (ukb-b-4078) (👉 📊) Ankylosis of joint Inverse variance weighted 126 0.034164611 0.017113536 0.045895817
Wholemeal pasta (ukb-b-4150) (👉 📊) Ankylosis of joint MR Egger 22 -16.34790089 6.23159057 0.016280808
Sushi (ukb-b-5213) (👉 📊) Ankylosis of joint Inverse variance weighted 69 8.325581161 3.603230481 0.020855622
Fresh tomato (ukb-b-730) (👉 📊) Ankylosis of joint Inverse variance weighted 10 3.030238982 1.265511401 0.01664405
Other egg (ukb-b-8266) (👉 📊) Ankylosis of joint Weighted median 21 16.94829793 7.333196857 0.020823216
Other egg (ukb-b-8266) (👉 📊) Ankylosis of joint Inverse variance weighted 21 14.08288675 5.901759765 0.017022646
Stewed fruit (ukb-b-8676) (👉 📊) Ankylosis of joint MR Egger 9 20.63924509 8.27407786 0.041326716
Other cereal (ukb-b-8917) (👉 📊) Ankylosis of joint Inverse variance weighted 14 10.62336619 5.395487673 0.04896052
Chocolate sweet (ukb-b-9835) (👉 📊) Ankylosis of joint Simple mode 20 -8.049002794 3.748509258 0.044890259

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other sweets (ukb-b-139) Ankylosis of joint rs114773112 30.3971885292835 13.5530539022814 0.024907814124413
Other sweets (ukb-b-139) Ankylosis of joint rs4849108 23.9292721982904 11.2842719351662 0.0339566340736351
Other sweets (ukb-b-139) Ankylosis of joint rs78668444 23.7320169473385 10.1861544525921 0.0198150926445658
Other sweets (ukb-b-139) Ankylosis of joint All - Inverse variance weighted 3.89489533351374 1.95912361210779 0.0468027942289698
Shellfish (ukb-b-143) Ankylosis of joint All - Inverse variance weighted -10.5929584935833 4.50869995887108 0.0188012432488534
Cereal (ukb-b-15926) Ankylosis of joint rs10829656 41.2686882824386 18.3699366408816 0.0246698206532115
Cereal (ukb-b-15926) Ankylosis of joint rs13265333 -42.4608986327099 17.3957762697463 0.0146517643515149
Cereal (ukb-b-15926) Ankylosis of joint rs17811999 41.6028797219579 17.543133766395 0.0177178558407487
Cereal (ukb-b-15926) Ankylosis of joint rs2927238 35.5828819596936 14.7464988044698 0.0158230549608582
Cereal (ukb-b-15926) Ankylosis of joint rs4007 -30.9332043674783 15.5224047171742 0.0462822491120211
Cereal (ukb-b-15926) Ankylosis of joint rs4526484 -44.3196528185213 18.551113346185 0.0168917170645373
Cereal (ukb-b-15926) Ankylosis of joint rs4917456 36.2205816089564 17.5268332697885 0.0387738626151472
Cereal (ukb-b-15926) Ankylosis of joint rs72753733 40.0121137592115 19.2535354740426 0.0376937331402777
Cereal (ukb-b-15926) Ankylosis of joint rs79598313 33.3919278282245 14.1736269298912 0.0184769081024463
Cereal (ukb-b-15926) Ankylosis of joint rs9308964 -39.6103057084528 15.8255161898855 0.0123166681473732
Rose wine (ukb-b-16124) Ankylosis of joint rs13224220 8.8789547778409 3.28690096898746 0.0069065898674871
Rose wine (ukb-b-16124) Ankylosis of joint rs79763018 167.868999368623 73.0591933304819 0.0215781750966566
Rose wine (ukb-b-16124) Ankylosis of joint All - Inverse variance weighted 5.96037133761539 2.60246810921742 0.0220052979895073
Rose wine (ukb-b-16124) Ankylosis of joint All - MR Egger 11.2058442803742 5.10789791233335 0.0486727730788037
Carrot (ukb-b-16710) Ankylosis of joint rs116391685 9.21055204646342 3.63924360052408 0.0113771133452719
Carrot (ukb-b-16710) Ankylosis of joint All - Inverse variance weighted 6.23630959509159 2.03619880878304 0.0021933418306671
Fruit smoothie (ukb-b-1780) Ankylosis of joint rs115361090 50.7902822659581 23.9056484400047 0.0336188105665903
Fruit smoothie (ukb-b-1780) Ankylosis of joint All - MR Egger -11.6916372828329 4.21127813666487 0.011012553525054
Espresso (ukb-b-19142) Ankylosis of joint All - MR Egger 7.67124534626227 3.29114834398653 0.0264387533605141
Bran cereal (ukb-b-19498) Ankylosis of joint All - Inverse variance weighted -6.94703778197546 3.40320656284775 0.0412189089405968
Cheesy biscuits (ukb-b-19847) Ankylosis of joint rs62139637 52.9642632363611 22.8020248950856 0.0201905595195099
Cheesy biscuits (ukb-b-19847) Ankylosis of joint All - Inverse variance weighted 10.8337277481249 4.35976360597625 0.0129575210631825
Green tea (ukb-b-4078) Ankylosis of joint rs139972448 0.738363108562846 0.283165561829937 0.0091197691886343
Green tea (ukb-b-4078) Ankylosis of joint rs146320720 4.44221938837357 1.79788301808114 0.0134809088515011
Green tea (ukb-b-4078) Ankylosis of joint rs55661362 0.510971880808202 0.209170214041609 0.0145717106593223
Green tea (ukb-b-4078) Ankylosis of joint rs74931176 1.03900077636206 0.380097730282687 0.0062663305772029
Green tea (ukb-b-4078) Ankylosis of joint rs77747372 0.298419876923318 0.133756890299007 0.0256770413681256
Green tea (ukb-b-4078) Ankylosis of joint All - Inverse variance weighted 0.0341646108450745 0.017113535885076 0.045895817043871
Green tea (ukb-b-4078) Ankylosis of joint All - MR Egger 0.0693899415337683 0.0316630742520023 0.0302832635057563
Wholemeal pasta (ukb-b-4150) Ankylosis of joint All - MR Egger -16.3479008873285 6.23159057024494 0.0162808081200655
Sushi (ukb-b-5213) Ankylosis of joint rs141181868 88.7253988948904 30.1545911715403 0.0032573023658669
Sushi (ukb-b-5213) Ankylosis of joint rs5996535 63.7953495716711 28.175527445197 0.0235611176649612
Sushi (ukb-b-5213) Ankylosis of joint All - Inverse variance weighted 8.32558116095372 3.60323048076552 0.0208556219207659
Fresh tomato (ukb-b-730) Ankylosis of joint rs76800056 8.21186117352099 4.12773198810612 0.0466530310341851
Fresh tomato (ukb-b-730) Ankylosis of joint All - Inverse variance weighted 3.03023898154553 1.26551140089799 0.0166440500405374
Other egg (ukb-b-8266) Ankylosis of joint rs142712099 97.4468408454807 41.5236635807551 0.0189365084726962
Other egg (ukb-b-8266) Ankylosis of joint All - Inverse variance weighted 14.082886752713 5.90175976484208 0.0170226462693312
Stewed fruit (ukb-b-8676) Ankylosis of joint rs2519958 -27.6697350137438 13.9562259937743 0.047411155315072
Stewed fruit (ukb-b-8676) Ankylosis of joint All - MR Egger 20.6392450893845 8.27407786006775 0.0413267161272531
Other cereal (ukb-b-8917) Ankylosis of joint rs10142984 43.357453974682 21.728477364822 0.0459970128165218
Other cereal (ukb-b-8917) Ankylosis of joint All - Inverse variance weighted 10.6233661864056 5.39548767311537 0.0489605203026357
Chocolate sweet (ukb-b-9835) Ankylosis of joint rs117585054 45.1476070016557 13.051348363072 0.0005417234556761