ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
Intake (exposure) | Outcome | SNP | b | se | P-value |
---|---|---|---|---|---|
Oily fish (ukb-b-10546) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | 0.683159126674625 | 0.309143150613054 | 0.0271157684898822 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs1032001 | -3.59239463769386 | 1.69662983997515 | 0.0342283825822445 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs11264431 | -5.33030164661591 | 1.62145539599855 | 0.001011327808848 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs11756671 | 4.72140924402231 | 1.6750418760469 | 0.0048221367307674 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs1235070 | -3.46295870951784 | 1.52829555292496 | 0.0234577544222873 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs12666766 | 3.52887300546841 | 1.63423635367748 | 0.0308237479359129 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs13181793 | -3.19781542496811 | 1.53602931929648 | 0.0373542227954841 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs141707337 | -2.76825205289846 | 1.27321849227862 | 0.0296889152295895 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs1519043 | -3.89233584787752 | 1.58907289202339 | 0.0143079259780989 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs1647396 | 3.30653473510616 | 1.44300144300144 | 0.0219386386722054 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs17481439 | -7.1847765373815 | 1.64507662996488 | 1.25710244502369e-05 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs1965353 | -3.84481940677906 | 1.77725537956085 | 0.0305145303998379 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs215629 | -5.16920224949422 | 1.73792144595064 | 0.0029360137896547 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs2832747 | 4.07494784456706 | 1.68652147633996 | 0.0156840915676727 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs2900884 | 3.35305182237004 | 1.57202700615181 | 0.0329289940403514 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs35625885 | 2.95048805740584 | 1.49619069848167 | 0.0486096065185274 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs4655801 | -3.28493962479056 | 1.45263661799784 | 0.0237367485980475 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs4692708 | -3.19081046585833 | 1.50035981479721 | 0.0334452808692094 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs6539284 | 4.78651480335471 | 1.44342040863729 | 0.0009128578709145 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs6857 | 3.10333921935535 | 1.45613156576971 | 0.0330708805048061 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs72845670 | -3.29541466587919 | 1.50647527583049 | 0.0287060432176033 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | rs7607369 | -3.5077288941736 | 1.47783251231527 | 0.0176173769095845 |
Cheese (ukb-b-1489) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | -0.28604260107942 | 0.122164612492339 | 0.019208885343152 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs10122671 | 4.38929046824715 | 2.1061854454161 | 0.0371601672645792 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs13066686 | -5.52275245575668 | 2.04330164853577 | 0.0068746285841189 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs17662627 | 6.02216278181123 | 2.08890587186346 | 0.0039399894965277 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs2302316 | -5.04503528817169 | 1.77794624645764 | 0.0045459310221707 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs2504706 | -2.68987254734781 | 1.21566837006925 | 0.0269204269861268 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs2799849 | 3.16329923999708 | 1.53298347784474 | 0.0390659010768088 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs489693 | 5.08044716031341 | 2.10504583534898 | 0.0158017955474975 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs4988235 | 3.44736842105263 | 1.54385964912281 | 0.0255519420167032 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs56131196 | -3.60507487890503 | 1.08874372305915 | 0.0009288865807935 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs7306606 | -4.62314791094483 | 2.07326736212474 | 0.0257550746415925 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs8111216 | 4.87150957501601 | 2.18578472578284 | 0.0258323140384877 |
Cereal (ukb-b-15926) | Gonarthrosis, primary, with knee surgery | rs9354833 | 4.56612817432569 | 2.09181264530627 | 0.0290463319814886 |
Rose wine (ukb-b-16124) | Gonarthrosis, primary, with knee surgery | rs12456862 | 2.63822238395233 | 1.30394899436724 | 0.0430467799220495 |
Rose wine (ukb-b-16124) | Gonarthrosis, primary, with knee surgery | rs71641030 | 3.62455540906605 | 1.71689466745234 | 0.0347627626222285 |
Rose wine (ukb-b-16124) | Gonarthrosis, primary, with knee surgery | All - MR Egger | -2.02711547259886 | 0.565899459740203 | 0.0037676246117481 |
Other vegetarian alternative (ukb-b-16150) | Gonarthrosis, primary, with knee surgery | rs145564253 | 5.61247216035635 | 1.87487345616522 | 0.0027577896467481 |
Other vegetarian alternative (ukb-b-16150) | Gonarthrosis, primary, with knee surgery | rs146608609 | -6.4581990578729 | 2.58674014508238 | 0.0125370681172358 |
Other vegetarian alternative (ukb-b-16150) | Gonarthrosis, primary, with knee surgery | rs7034934 | 6.70531777238979 | 3.12496074169922 | 0.0318946345606387 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs10026792 | -3.47577559581432 | 1.65952150463283 | 0.0362204071190664 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs10740991 | -3.99665451938587 | 1.15299599737141 | 0.0005276324545145 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs1622515 | -3.66031103568652 | 1.73436225382392 | 0.0348183128146934 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs17175518 | 4.63631460830535 | 1.92237434978515 | 0.0158755231158103 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs1812195 | -4.6870539810004 | 2.09096643763928 | 0.0249889804373504 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs193003548 | -6.24581192763011 | 2.55472414563324 | 0.0144928974795573 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs2389238 | -4.16160915554014 | 2.06504090672636 | 0.0438766622748974 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs3757323 | 4.88950835150507 | 2.01200458602163 | 0.0150918423233647 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs3764002 | -4.22969934839767 | 1.37941546317113 | 0.0021672694575244 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs429358 | -3.12868209280754 | 1.14818621675149 | 0.006432275156939 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs4769824 | -6.45110891034219 | 2.17976922165859 | 0.003081011295338 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs565226 | -4.54917872888299 | 1.80250477936873 | 0.0116090811467694 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs57499472 | 3.65202460375029 | 1.7352161100692 | 0.0353216845432994 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs62007687 | -7.51418372800689 | 2.11301106336434 | 0.0003763296464313 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs6712271 | 5.45844196284108 | 2.1369739228125 | 0.0106405903029615 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs75265668 | 10.8348331898688 | 4.77671700967734 | 0.0233134018002045 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | rs7599488 | -3.27399811817117 | 1.65140081033854 | 0.0474168071151743 |
Dried fruit (ukb-b-16576) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | -0.489861117271645 | 0.177046445082 | 0.005660063387601 |
Fruitcake (ukb-b-17775) | Gonarthrosis, primary, with knee surgery | rs7137088 | 3.27467290272926 | 1.53928127405127 | 0.0333865428611683 |
Fruitcake (ukb-b-17775) | Gonarthrosis, primary, with knee surgery | rs73148292 | 3.38239036389855 | 1.42081601492917 | 0.0172846090328266 |
Fruitcake (ukb-b-17775) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | 1.16412009268788 | 0.456129662713943 | 0.0107054504475532 |
Cheesecake (ukb-b-1814) | Gonarthrosis, primary, with knee surgery | rs12724320 | -5.87446569614841 | 2.13176487117963 | 0.0058569942057487 |
Cheesecake (ukb-b-1814) | Gonarthrosis, primary, with knee surgery | rs145774296 | 4.36445596058781 | 1.6946342203699 | 0.0100107994024268 |
Cheesecake (ukb-b-1814) | Gonarthrosis, primary, with knee surgery | rs3931851 | 3.86667522571339 | 1.95599391300736 | 0.0480603997401257 |
Cheesecake (ukb-b-1814) | Gonarthrosis, primary, with knee surgery | rs650058 | 5.69307252289336 | 2.19691180344017 | 0.0095586914577666 |
Cheesecake (ukb-b-1814) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | 1.18924806814034 | 0.579674672732931 | 0.0402106480323177 |
Other savoury snack (ukb-b-18718) | Gonarthrosis, primary, with knee surgery | rs113470581 | 4.52755947334986 | 1.56371833523487 | 0.003786992662236 |
Other savoury snack (ukb-b-18718) | Gonarthrosis, primary, with knee surgery | rs113602890 | 7.90302436342558 | 4.01874017724288 | 0.0492359490849507 |
Other savoury snack (ukb-b-18718) | Gonarthrosis, primary, with knee surgery | rs17810066 | 3.94072714513212 | 1.98655834165565 | 0.0472897785574767 |
Other savoury snack (ukb-b-18718) | Gonarthrosis, primary, with knee surgery | All - MR Egger | 2.36915351675613 | 0.858568924935158 | 0.0114403848664689 |
Grapefruit (ukb-b-18758) | Gonarthrosis, primary, with knee surgery | rs149410520 | 3.06209495677417 | 1.29444069551784 | 0.0180021564059769 |
Grapefruit (ukb-b-18758) | Gonarthrosis, primary, with knee surgery | rs74352714 | 10.6804370414686 | 4.0618407380585 | 0.0085521255048909 |
Grapefruit (ukb-b-18758) | Gonarthrosis, primary, with knee surgery | rs75128811 | 4.48363421336394 | 1.35656892413649 | 0.000949329640918 |
Grapefruit (ukb-b-18758) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | 1.72875973892429 | 0.635140169861441 | 0.0064916528797442 |
Grapefruit (ukb-b-18758) | Gonarthrosis, primary, with knee surgery | All - MR Egger | 3.9900760404511 | 1.1291001450097 | 0.0033052334958468 |
Beef (ukb-b-2862) | Gonarthrosis, primary, with knee surgery | rs1421085 | -7.42378249967005 | 1.43526461660288 | 2.31089124212718e-07 |
Beef (ukb-b-2862) | Gonarthrosis, primary, with knee surgery | rs1556147 | 4.64999460358544 | 2.01735123799802 | 0.0211665734149196 |
Beef (ukb-b-2862) | Gonarthrosis, primary, with knee surgery | rs2403202 | 3.9110460359533 | 1.98275871460585 | 0.0485494233126332 |
Beef (ukb-b-2862) | Gonarthrosis, primary, with knee surgery | rs429358 | 4.20162408931145 | 1.5419421738018 | 0.006432275156939 |
Beef (ukb-b-2862) | Gonarthrosis, primary, with knee surgery | rs6851529 | -4.66363383812037 | 2.21239772374443 | 0.0350349213899708 |
Beef (ukb-b-2862) | Gonarthrosis, primary, with knee surgery | rs7018123 | 4.71545810791663 | 2.09059719070195 | 0.0240984792962833 |
Beef (ukb-b-2862) | Gonarthrosis, primary, with knee surgery | rs7174015 | 9.98669637928371 | 2.16737655233855 | 4.07079387762762e-06 |
Beef (ukb-b-2862) | Gonarthrosis, primary, with knee surgery | rs77862656 | 3.36240892115641 | 1.63223734036719 | 0.0393985408187538 |
Beef (ukb-b-2862) | Gonarthrosis, primary, with knee surgery | rs79809011 | 7.4520747131967 | 3.18254553748668 | 0.0192040925850924 |
White wine (ukb-b-311) | Gonarthrosis, primary, with knee surgery | rs1229984 | -2.749751238458 | 1.39686887383837 | 0.0490093132884874 |
White wine (ukb-b-311) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | -0.447561867038355 | 0.181860339807763 | 0.0138542783849149 |
Drinking water (ukb-b-3975) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | -0.118585146822028 | 0.0527131613519401 | 0.0244723970540353 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | rs13387939 | 4.27644692494473 | 1.40132159122483 | 0.0022753110389185 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | rs1421085 | 4.85368826378178 | 0.93837973099781 | 2.31089124212721e-07 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | rs144620429 | 5.91997462868016 | 2.06141973677256 | 0.0040814780475456 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | rs2189234 | -5.19681302187167 | 1.77232351612965 | 0.0033656624794194 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | rs2231142 | 5.23526884458094 | 2.60172175103035 | 0.0441954429138822 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | rs2465037 | 4.4865825785152 | 1.77770253110979 | 0.0116090811467694 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | rs476828 | 3.0381469033385 | 1.27406160462582 | 0.0170969855522096 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | rs56113850 | 3.1657811426812 | 1.35789116344431 | 0.0197325225646819 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | rs56791931 | 5.85736016645394 | 2.28174776633504 | 0.0102567878245308 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | rs9953004 | 4.83056169262882 | 2.31358481068012 | 0.0368057655775258 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | 0.667207371801397 | 0.186892324492389 | 0.0003569682971955 |
Coffee (ukb-b-5237) | Gonarthrosis, primary, with knee surgery | All - MR Egger | 0.847561439280146 | 0.406342983241557 | 0.0392057679244938 |
Tofu (ukb-b-5522) | Gonarthrosis, primary, with knee surgery | rs143090941 | 15.0537400776407 | 7.41642041833246 | 0.0423783824432623 |
Tofu (ukb-b-5522) | Gonarthrosis, primary, with knee surgery | rs146906987 | 7.97393570108212 | 2.69019648905195 | 0.0030359738529432 |
Tofu (ukb-b-5522) | Gonarthrosis, primary, with knee surgery | rs16879193 | -14.3075901864522 | 5.93465959502356 | 0.0159152741539698 |
Tofu (ukb-b-5522) | Gonarthrosis, primary, with knee surgery | rs73784728 | 12.6497520720982 | 5.50749816014574 | 0.021628831376889 |
Tofu (ukb-b-5522) | Gonarthrosis, primary, with knee surgery | All - MR Egger | 2.23847177582685 | 0.95826647266192 | 0.0239071613027841 |
Yorkshire pudding (ukb-b-5605) | Gonarthrosis, primary, with knee surgery | rs11981557 | 6.63826607709422 | 3.31495101455902 | 0.0452284981496325 |
Yorkshire pudding (ukb-b-5605) | Gonarthrosis, primary, with knee surgery | rs58771985 | 4.56670107822895 | 2.0216792842395 | 0.0238917682858998 |
Yorkshire pudding (ukb-b-5605) | Gonarthrosis, primary, with knee surgery | rs79273432 | 5.14506840618309 | 2.27058696010214 | 0.0234535849222444 |
Yorkshire pudding (ukb-b-5605) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | 0.964656405547187 | 0.460748892571645 | 0.036289334580258 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | rs10884893 | 5.81149321522273 | 2.42615736169493 | 0.0166045593653662 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | rs11031113 | 5.55306933286762 | 2.52412242403074 | 0.0278068950269972 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | rs12097622 | 6.40305113913846 | 2.41858590243486 | 0.0081104734618914 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | rs12721051 | 5.35438420537541 | 1.59337415175069 | 0.0007782798396447 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | rs2835744 | 4.90440246752749 | 2.43942935233789 | 0.0443813409469169 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | rs62019153 | 5.57043361192943 | 2.40008662638242 | 0.0202906095609727 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | rs79729037 | 6.96722712049757 | 2.98168272845328 | 0.0194560260462053 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | rs9527954 | 5.73705871604882 | 2.58103755154089 | 0.0262311593509928 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | rs9696811 | 7.120345822553 | 2.62188434961297 | 0.0066128618258669 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | rs9783122 | -5.63630426559387 | 2.17692822495212 | 0.0096224655538291 |
Pork (ukb-b-5640) | Gonarthrosis, primary, with knee surgery | All - Inverse variance weighted | 0.678997798680273 | 0.302401580297065 | 0.0247455855066773 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs1481012 | 2.49585611675272 | 1.24983329205327 | 0.045830482336422 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs2117137 | 3.10893588204513 | 1.31591097977653 | 0.0181485618813399 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs2207055 | 5.66307455465142 | 1.67692984385309 | 0.0007326794862781 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs2251012 | 3.81316120215245 | 1.75913836792633 | 0.0301868449021406 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs2351822 | 3.89290392313118 | 1.57548111712603 | 0.0134762107114617 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs2416721 | 4.22740001436059 | 1.74122208659439 | 0.0151892496849092 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs2478875 | -2.03705987403114 | 1.03679953229836 | 0.0494422870965604 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs35596618 | 2.84393303383789 | 1.29368930713931 | 0.0279268630187314 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs4683352 | 3.80744244017791 | 1.93786868592015 | 0.0494422870965603 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs6265 | 3.83106425546104 | 1.68141153434123 | 0.0226979345043779 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs75396527 | -2.22782124386686 | 1.07533363069764 | 0.0382888663869664 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs80318442 | 2.97458514452518 | 1.34451248532538 | 0.0269397720130936 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs897623 | 4.19148644618373 | 1.70883678190568 | 0.0141737231063884 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs984616 | -3.84133611691023 | 1.49478079331942 | 0.010174772641217 |
Tea (ukb-b-6066) | Gonarthrosis, primary, with knee surgery | rs9937354 | -6.43613888435529 | 1.22762075743491 | 1.58179755608868e-07 |