ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Disorders of continuity of bone (finn-b-M13_BONECONTINUITY)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Satsuma (ukb-b-11563) (👉 📊) Disorders of continuity of bone MR Egger 18 -2.091038634 0.967971164 0.046271417
Pineapple (ukb-b-1164) (👉 📊) Disorders of continuity of bone Weighted median 16 -3.07203046 1.38341904 0.026377569
Beetroot (ukb-b-11880) (👉 📊) Disorders of continuity of bone MR Egger 10 -3.151648173 1.172506373 0.027583749
Herbal tea (ukb-b-13344) (👉 📊) Disorders of continuity of bone Simple mode 121 -0.035041175 0.016973094 0.041123885
Hot chocolate (ukb-b-16449) (👉 📊) Disorders of continuity of bone Weighted median 18 -2.952857023 1.29337472 0.02242661
Hot chocolate (ukb-b-16449) (👉 📊) Disorders of continuity of bone Inverse variance weighted 18 -2.472877528 0.975333079 0.011231306
Low calorie hot chocolate (ukb-b-1795) (👉 📊) Disorders of continuity of bone Inverse variance weighted 24 2.45124401 1.163251345 0.03509721
Mixed fruit (ukb-b-18956) (👉 📊) Disorders of continuity of bone MR Egger 16 2.185516644 0.753893931 0.011665748
Mixed fruit (ukb-b-18956) (👉 📊) Disorders of continuity of bone Weighted median 16 2.332828222 0.792762101 0.00325407
Mixed fruit (ukb-b-18956) (👉 📊) Disorders of continuity of bone Inverse variance weighted 16 1.820794194 0.52881819 0.000575005
Mixed fruit (ukb-b-18956) (👉 📊) Disorders of continuity of bone Weighted mode 16 2.082050051 0.729602598 0.01207632
Quorn (ukb-b-19069) (👉 📊) Disorders of continuity of bone Inverse variance weighted 25 -2.458191507 1.11178253 0.027033325
Green bean (ukb-b-2299) (👉 📊) Disorders of continuity of bone Weighted median 17 1.743884103 0.717040558 0.01501331
Green bean (ukb-b-2299) (👉 📊) Disorders of continuity of bone Weighted mode 17 1.874902778 0.826931895 0.037580606
Vegetarian sausages/burgers (ukb-b-3383) (👉 📊) Disorders of continuity of bone Inverse variance weighted 34 -2.10577841 0.913647741 0.021177587
Crumbed or deep-fried poultry (ukb-b-39) (👉 📊) Disorders of continuity of bone Inverse variance weighted 12 2.668831315 1.19757688 0.025845454
Wholemeal pasta (ukb-b-4150) (👉 📊) Disorders of continuity of bone MR Egger 22 3.746399726 1.770953096 0.047133984
Seeds (ukb-b-4548) (👉 📊) Disorders of continuity of bone MR Egger 15 6.463944108 2.760049432 0.035757321
Yogurt (ukb-b-7753) (👉 📊) Disorders of continuity of bone Inverse variance weighted 9 -1.39307866 0.623146324 0.025380853
Onion (ukb-b-8124) (👉 📊) Disorders of continuity of bone MR Egger 13 3.012178854 1.336120942 0.04553554

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Satsuma (ukb-b-11563) Disorders of continuity of bone All - MR Egger -2.09103863356583 0.967971164348836 0.0462714168555939
Beetroot (ukb-b-11880) Disorders of continuity of bone rs13101707 5.83802380665891 2.67390403358423 0.0290112715141918
Beetroot (ukb-b-11880) Disorders of continuity of bone rs189837126 -2.33185884481126 0.993311300127394 0.0188967798736299
Beetroot (ukb-b-11880) Disorders of continuity of bone All - MR Egger -3.15164817260061 1.17250637300863 0.0275837485442699
Herbal tea (ukb-b-13344) Disorders of continuity of bone rs113362806 -0.0814446398846229 0.0371336339068492 0.0282868562600413
Herbal tea (ukb-b-13344) Disorders of continuity of bone rs115494331 0.459541775566984 0.167987522131355 0.0062272171532371
Herbal tea (ukb-b-13344) Disorders of continuity of bone rs140551976 -0.21549005394312 0.0923842607847014 0.0196722612054013
Herbal tea (ukb-b-13344) Disorders of continuity of bone rs149369996 0.110708981712549 0.0414178763212564 0.0075181670474509
Herbal tea (ukb-b-13344) Disorders of continuity of bone rs79919614 -0.0861071283272703 0.043725041769857 0.0489202166782753
Hot chocolate (ukb-b-16449) Disorders of continuity of bone rs114421178 10.1103945786425 4.89407170936337 0.0388430980554763
Hot chocolate (ukb-b-16449) Disorders of continuity of bone All - Inverse variance weighted -2.4728775278525 0.975333078645584 0.0112313060523876
Low calorie hot chocolate (ukb-b-1795) Disorders of continuity of bone rs115441677 14.7747080875857 6.20239260727334 0.0172143076179301
Low calorie hot chocolate (ukb-b-1795) Disorders of continuity of bone rs116707297 14.9298143476292 7.19322077754059 0.0379365556269824
Low calorie hot chocolate (ukb-b-1795) Disorders of continuity of bone All - Inverse variance weighted 2.45124401047335 1.16325134512389 0.0350972098483411
Mixed fruit (ukb-b-18956) Disorders of continuity of bone rs139215765 13.8279848515049 6.28418931189511 0.0277756550209
Mixed fruit (ukb-b-18956) Disorders of continuity of bone rs139486419 2.37272900276548 0.730849121158993 0.0011681809976894
Mixed fruit (ukb-b-18956) Disorders of continuity of bone All - Inverse variance weighted 1.82079419361148 0.528818190360228 0.0005750050672925
Mixed fruit (ukb-b-18956) Disorders of continuity of bone All - MR Egger 2.18551664412188 0.753893931491431 0.0116657483486664
Quorn (ukb-b-19069) Disorders of continuity of bone rs76252718 -8.69527256564117 4.22262437692479 0.0394740752286356
Quorn (ukb-b-19069) Disorders of continuity of bone All - Inverse variance weighted -2.45819150655773 1.11178252984706 0.0270333249691371
Green bean (ukb-b-2299) Disorders of continuity of bone rs11485443 -7.93122818341384 3.34603446202373 0.0177718941554428
Green bean (ukb-b-2299) Disorders of continuity of bone rs7047957 -3.85637464992887 1.9460823349409 0.0475229972117546
Vegetarian sausages/burgers (ukb-b-3383) Disorders of continuity of bone rs75172571 -11.2583273803944 5.14915748405636 0.0287833803017912
Vegetarian sausages/burgers (ukb-b-3383) Disorders of continuity of bone All - Inverse variance weighted -2.10577841028335 0.913647740699114 0.0211775871528707
Crumbed or deep-fried poultry (ukb-b-39) Disorders of continuity of bone rs142223998 6.18000992962575 2.21446415483912 0.0052586505688514
Crumbed or deep-fried poultry (ukb-b-39) Disorders of continuity of bone rs79164310 6.79969971268321 2.93998577172661 0.0207317553113035
Crumbed or deep-fried poultry (ukb-b-39) Disorders of continuity of bone All - Inverse variance weighted 2.6688313148856 1.19757687978989 0.0258454538901906
Wholemeal pasta (ukb-b-4150) Disorders of continuity of bone All - MR Egger 3.74639972550251 1.77095309570287 0.0471339844455406
Seeds (ukb-b-4548) Disorders of continuity of bone rs1441393 -13.4335695623595 5.57890841199962 0.0160436614260102
Seeds (ukb-b-4548) Disorders of continuity of bone rs1713456 -11.3396026890249 5.24019941083163 0.030467115173737
Seeds (ukb-b-4548) Disorders of continuity of bone All - MR Egger 6.46394410782556 2.7600494319847 0.0357573214748203
Yogurt (ukb-b-7753) Disorders of continuity of bone All - Inverse variance weighted -1.39307865960749 0.623146324244689 0.0253808531433001
Onion (ukb-b-8124) Disorders of continuity of bone rs144108770 10.4847829150328 4.06790477865264 0.0099534988519446
Onion (ukb-b-8124) Disorders of continuity of bone All - MR Egger 3.01217885388694 1.336120942464 0.0455355402898776