ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sweet pepper (ukb-b-10932) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 9 -3.531199164 1.178831682 0.002739885
Omelette (ukb-b-11272) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 15 4.131704031 1.623990965 0.010953874
Chocolate-covered raisin (ukb-b-1160) (👉 📊) Other disorders of bone density and structure Weighted median 51 -3.897948782 1.817582619 0.031986555
Beetroot (ukb-b-11880) (👉 📊) Other disorders of bone density and structure Weighted median 10 3.977072803 1.855321024 0.032064663
Unsalted nuts (ukb-b-12217) (👉 📊) Other disorders of bone density and structure Weighted median 15 -5.008042152 2.303162062 0.029673591
Unsalted nuts (ukb-b-12217) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 15 -3.880242666 1.722008816 0.024238769
Avocado (ukb-b-12236) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 24 -3.423519497 1.522809993 0.024566032
Scotch egg (ukb-b-13516) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 106 5.664146112 2.661128328 0.03329769
Lobster/crab (ukb-b-14746) (👉 📊) Other disorders of bone density and structure Simple mode 54 -19.94970638 9.414342172 0.038787204
Cheese (ukb-b-1489) (👉 📊) Other disorders of bone density and structure Weighted median 198 -1.535026562 0.672929373 0.022541882
Cheese (ukb-b-1489) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 198 -1.654188394 0.451112429 0.0002455
Savoury biscuits (ukb-b-1503) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 32 -6.765591318 2.623817694 0.009922183
Mashed potato (ukb-b-15710) (👉 📊) Other disorders of bone density and structure Weighted median 11 -3.599515833 1.700659489 0.034298807
Pea (ukb-b-15945) (👉 📊) Other disorders of bone density and structure Weighted median 11 -2.608638846 1.324147228 0.048832415
Sprouts (ukb-b-16077) (👉 📊) Other disorders of bone density and structure MR Egger 13 8.802187026 3.502550711 0.028828185
Fruitcake (ukb-b-17775) (👉 📊) Other disorders of bone density and structure Weighted median 13 5.814885225 2.870377402 0.042782617
Fruit smoothie (ukb-b-1780) (👉 📊) Other disorders of bone density and structure MR Egger 24 -5.166340996 2.150264265 0.025152087
Melon (ukb-b-19862) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 16 3.396053342 1.484196682 0.02212923
Pure fruit/vegetable juice (ukb-b-337) (👉 📊) Other disorders of bone density and structure Weighted median 8 6.251949355 2.3049167 0.006678978
Pure fruit/vegetable juice (ukb-b-337) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 8 5.375393826 1.929202671 0.00533087
Crumbed or deep-fried poultry (ukb-b-39) (👉 📊) Other disorders of bone density and structure Simple mode 12 -11.56932821 5.225680312 0.048880946
Turnip/swede (ukb-b-5008) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 19 -3.579524136 1.756316249 0.0415413
Oat crunch (ukb-b-5186) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 13 -5.863456293 2.803320847 0.036473341
Cheese spread (ukb-b-6185) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 24 5.970546854 2.766586846 0.030920738
Other meat (ukb-b-770) (👉 📊) Other disorders of bone density and structure Inverse variance weighted 25 -6.108961718 2.486827238 0.014028672
Squash (ukb-b-8793) (👉 📊) Other disorders of bone density and structure Weighted median 18 -2.596104623 1.226740389 0.034322492

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sweet pepper (ukb-b-10932) Other disorders of bone density and structure rs1267469 -6.39432544438602 3.02407832558808 0.0344750725746219
Sweet pepper (ukb-b-10932) Other disorders of bone density and structure All - Inverse variance weighted -3.53119916358914 1.17883168162413 0.0027398854808323
Omelette (ukb-b-11272) Other disorders of bone density and structure rs146053608 12.0343583642459 4.92474140323234 0.0145394092629217
Omelette (ukb-b-11272) Other disorders of bone density and structure rs2074128 17.1618741027537 6.21158543027425 0.0057293573388979
Omelette (ukb-b-11272) Other disorders of bone density and structure rs72940321 15.5696547429061 7.81985909462458 0.0464764548533175
Omelette (ukb-b-11272) Other disorders of bone density and structure rs75079782 31.5335591019997 12.5261040995752 0.0118215291433782
Omelette (ukb-b-11272) Other disorders of bone density and structure All - Inverse variance weighted 4.13170403074871 1.62399096515507 0.0109538737186934
Chocolate-covered raisin (ukb-b-1160) Other disorders of bone density and structure rs4244577 -15.838129644638 7.10174590310307 0.025735888242578
Beetroot (ukb-b-11880) Other disorders of bone density and structure rs189837126 4.08024824706802 1.76454080551086 0.0207580190668226
Unsalted nuts (ukb-b-12217) Other disorders of bone density and structure All - Inverse variance weighted -3.88024266626579 1.72200881581866 0.0242387688034959
Avocado (ukb-b-12236) Other disorders of bone density and structure All - Inverse variance weighted -3.4235194974928 1.52280999304786 0.024566031824971
Scotch egg (ukb-b-13516) Other disorders of bone density and structure rs140220113 133.546827712744 60.7849642182517 0.028017789395384
Scotch egg (ukb-b-13516) Other disorders of bone density and structure rs149736097 42.4527663781961 21.337065372587 0.0466322203817422
Scotch egg (ukb-b-13516) Other disorders of bone density and structure rs149890841 188.581750437421 73.2537794393464 0.0100425122389028
Scotch egg (ukb-b-13516) Other disorders of bone density and structure rs1917920 57.4493069562823 21.7857885303653 0.0083640764903979
Scotch egg (ukb-b-13516) Other disorders of bone density and structure rs76118553 172.224363126522 69.7506620860425 0.013543706124162
Scotch egg (ukb-b-13516) Other disorders of bone density and structure All - Inverse variance weighted 5.66414611229672 2.66112832766104 0.0332976896173962
Lobster/crab (ukb-b-14746) Other disorders of bone density and structure rs9301989 78.0114320294154 31.474258200738 0.0131906936492191
Cheese (ukb-b-1489) Other disorders of bone density and structure rs1536456 -14.6436069890751 7.01042667520729 0.0367228048723741
Cheese (ukb-b-1489) Other disorders of bone density and structure rs17704703 20.6010686067291 7.75601658245417 0.0079040710692469
Cheese (ukb-b-1489) Other disorders of bone density and structure rs2968940 17.554578038449 6.98110133594005 0.0119172313092322
Cheese (ukb-b-1489) Other disorders of bone density and structure rs35625885 -21.8563537234202 6.69694956640394 0.0010999539229559
Cheese (ukb-b-1489) Other disorders of bone density and structure rs4692708 -15.1529552336081 6.6871240614265 0.0234520048464843
Cheese (ukb-b-1489) Other disorders of bone density and structure rs62048491 -19.233464414381 7.08991830105772 0.0066719232899667
Cheese (ukb-b-1489) Other disorders of bone density and structure rs6498981 16.3578285733913 7.29018186814131 0.024844226142368
Cheese (ukb-b-1489) Other disorders of bone density and structure rs6539284 -13.5216969314873 6.42902768214887 0.0354460354532454
Cheese (ukb-b-1489) Other disorders of bone density and structure All - Inverse variance weighted -1.65418839442679 0.451112428592911 0.0002454997504704
Savoury biscuits (ukb-b-1503) Other disorders of bone density and structure rs114398359 -37.3367573831073 18.3395446431368 0.0417643495699292
Savoury biscuits (ukb-b-1503) Other disorders of bone density and structure rs148469143 99.7111670475241 44.8019734985133 0.0260411435806702
Savoury biscuits (ukb-b-1503) Other disorders of bone density and structure All - Inverse variance weighted -6.76559131841795 2.62381769422386 0.0099221828297853
Mashed potato (ukb-b-15710) Other disorders of bone density and structure rs4756830 -7.26361152079652 3.48121869228418 0.0369320888436549
Mashed potato (ukb-b-15710) Other disorders of bone density and structure rs55768233 7.42498261238249 2.90733496383584 0.0106530175019687
Sprouts (ukb-b-16077) Other disorders of bone density and structure rs4682860 -16.9188031327398 6.43450030122498 0.0085538497779564
Sprouts (ukb-b-16077) Other disorders of bone density and structure All - MR Egger 8.80218702597396 3.50255071139821 0.0288281852429382
Fruitcake (ukb-b-17775) Other disorders of bone density and structure rs3779787 19.6782607578347 7.60661467100107 0.0096817490665523
Fruit smoothie (ukb-b-1780) Other disorders of bone density and structure rs3111807 18.1722032594587 8.46113167636171 0.0317354274773531
Fruit smoothie (ukb-b-1780) Other disorders of bone density and structure rs77343107 23.5086225498487 9.54691518583534 0.013799861644879
Fruit smoothie (ukb-b-1780) Other disorders of bone density and structure All - MR Egger -5.16634099603205 2.15026426475119 0.0251520870465162
Melon (ukb-b-19862) Other disorders of bone density and structure rs117641063 9.65384849123986 4.27908040881841 0.024067073604196
Melon (ukb-b-19862) Other disorders of bone density and structure All - Inverse variance weighted 3.39605334248646 1.48419668161796 0.0221292303363679
Pure fruit/vegetable juice (ukb-b-337) Other disorders of bone density and structure rs143987628 14.279350887675 5.19988690679413 0.0060310447846877
Pure fruit/vegetable juice (ukb-b-337) Other disorders of bone density and structure rs7628760 11.232497307278 3.5639578646195 0.0016232742990487
Pure fruit/vegetable juice (ukb-b-337) Other disorders of bone density and structure rs9599935 6.78091255364415 3.42518332224505 0.0477347167945431
Pure fruit/vegetable juice (ukb-b-337) Other disorders of bone density and structure All - Inverse variance weighted 5.37539382647384 1.92920267083819 0.0053308695201756
Turnip/swede (ukb-b-5008) Other disorders of bone density and structure rs142228490 -10.7166714076139 5.19053813479418 0.0389556389298303
Turnip/swede (ukb-b-5008) Other disorders of bone density and structure rs75193468 -31.7778113691822 13.243582584982 0.0164180386670244
Turnip/swede (ukb-b-5008) Other disorders of bone density and structure All - Inverse variance weighted -3.57952413629975 1.75631624900925 0.0415413001236751
Oat crunch (ukb-b-5186) Other disorders of bone density and structure rs72784689 -20.4166907732757 8.10624907591332 0.0117810375920488
Oat crunch (ukb-b-5186) Other disorders of bone density and structure All - Inverse variance weighted -5.86345629332293 2.80332084698868 0.0364733413531112
Cheese spread (ukb-b-6185) Other disorders of bone density and structure rs117478230 93.1478435491436 41.6383169400351 0.0252817435684886
Cheese spread (ukb-b-6185) Other disorders of bone density and structure rs77950337 68.3961392936111 27.1558161256788 0.0117803931628407
Cheese spread (ukb-b-6185) Other disorders of bone density and structure All - Inverse variance weighted 5.97054685400663 2.76658684648153 0.0309207382573026
Other meat (ukb-b-770) Other disorders of bone density and structure rs2826909 -26.5065349208187 12.3887605075182 0.0323900908251748
Other meat (ukb-b-770) Other disorders of bone density and structure rs3899492 -45.8017885161147 17.7222569941612 0.009754240239304
Other meat (ukb-b-770) Other disorders of bone density and structure All - Inverse variance weighted -6.10896171805994 2.48682723819262 0.0140286716067006
Squash (ukb-b-8793) Other disorders of bone density and structure rs4362145 10.2538674378201 3.44445159409977 0.0029115705211528
Squash (ukb-b-8793) Other disorders of bone density and structure rs73213334 -6.17631315280199 3.08815657640099 0.0455002638963584