ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Chondromalacia (finn-b-M13_CHONDROMALACIA)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Omelette (ukb-b-11272) (👉 📊) Chondromalacia Weighted median 15 4.004745616 1.574394368 0.010969349
Omelette (ukb-b-11272) (👉 📊) Chondromalacia Inverse variance weighted 15 2.759890535 1.124948681 0.014153336
Omelette (ukb-b-11272) (👉 📊) Chondromalacia Weighted mode 15 3.992074165 1.817095134 0.045358494
Chocolate bar (ukb-b-117) (👉 📊) Chondromalacia Inverse variance weighted 12 -1.679807395 0.836639022 0.044664096
Snackpot (ukb-b-12912) (👉 📊) Chondromalacia MR Egger 116 -18.50156568 7.943840669 0.021618279
Herbal tea (ukb-b-13344) (👉 📊) Chondromalacia Inverse variance weighted 121 -0.017928465 0.008555317 0.036118282
Orange (ukb-b-13520) (👉 📊) Chondromalacia Inverse variance weighted 7 3.22104623 1.497355866 0.031463879
Sweetcorn (ukb-b-13567) (👉 📊) Chondromalacia MR Egger 20 -4.719203473 2.238663166 0.049306546
Other sweets (ukb-b-139) (👉 📊) Chondromalacia Weighted median 26 3.003290935 1.372389757 0.028642961
Other sweets (ukb-b-139) (👉 📊) Chondromalacia Inverse variance weighted 26 1.908175081 0.908052393 0.035606468
Salted nuts (ukb-b-15960) (👉 📊) Chondromalacia MR Egger 23 -5.474201108 2.49923121 0.039923943
Other vegetarian alternative (ukb-b-16150) (👉 📊) Chondromalacia Inverse variance weighted 29 -4.683000675 2.24220032 0.036746112
Other fruit (ukb-b-18659) (👉 📊) Chondromalacia Inverse variance weighted 20 2.889559721 1.221367492 0.017989231
Low calorie drink (ukb-b-19703) (👉 📊) Chondromalacia Inverse variance weighted 19 1.605156832 0.621094025 0.009754793
Cheesy biscuits (ukb-b-19847) (👉 📊) Chondromalacia Inverse variance weighted 24 -4.049066749 2.006871431 0.043632784
Vegetarian sausages/burgers (ukb-b-3383) (👉 📊) Chondromalacia MR Egger 34 6.074314493 2.947348539 0.047513459
Turnip/swede (ukb-b-5008) (👉 📊) Chondromalacia MR Egger 19 5.283012294 2.474145272 0.047585651
Cucumber (ukb-b-588) (👉 📊) Chondromalacia MR Egger 17 3.323055802 1.167560283 0.012261522
Blue cheese (ukb-b-7429) (👉 📊) Chondromalacia Weighted median 20 6.447382303 3.139985664 0.040041956
Crumble (ukb-b-7641) (👉 📊) Chondromalacia Inverse variance weighted 24 3.085551977 1.538185455 0.044859581
Yogurt (ukb-b-7753) (👉 📊) Chondromalacia Inverse variance weighted 9 2.261495578 1.085879665 0.037284122

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Omelette (ukb-b-11272) Chondromalacia All - Inverse variance weighted 2.75989053532427 1.12494868081498 0.0141533362138705
Chocolate bar (ukb-b-117) Chondromalacia rs12584633 -8.02844362885652 3.2389035439844 0.0131842371187114
Chocolate bar (ukb-b-117) Chondromalacia All - Inverse variance weighted -1.67980739503948 0.836639022001447 0.0446640956563442
Snackpot (ukb-b-12912) Chondromalacia rs114880853 145.147055159291 55.079294512922 0.0084078283102817
Snackpot (ukb-b-12912) Chondromalacia rs11663173 -99.2770894478697 42.6064175547107 0.0198010203422768
Snackpot (ukb-b-12912) Chondromalacia rs117729114 58.7862865958825 28.3524848449564 0.0381342670071715
Snackpot (ukb-b-12912) Chondromalacia rs117983125 72.5599048048596 33.4910322723042 0.0302693911853277
Snackpot (ukb-b-12912) Chondromalacia rs187707703 -83.6786555212215 33.9412833361691 0.0136862447245267
Snackpot (ukb-b-12912) Chondromalacia rs72919932 95.218596260096 38.8707887506157 0.0143007715712302
Snackpot (ukb-b-12912) Chondromalacia rs73035011 60.8982974910394 30.2195340501792 0.0438840702123159
Snackpot (ukb-b-12912) Chondromalacia rs8015208 138.386229781784 48.6838147540824 0.0044754060147208
Snackpot (ukb-b-12912) Chondromalacia All - MR Egger -18.5015656790408 7.94384066911019 0.021618279137171
Herbal tea (ukb-b-13344) Chondromalacia rs116866633 -0.378300080362724 0.161072693540226 0.0188426454095802
Herbal tea (ukb-b-13344) Chondromalacia rs116986282 0.27033132203007 0.112163823474472 0.0159460865739859
Herbal tea (ukb-b-13344) Chondromalacia rs140493196 0.240094969580056 0.12023827189282 0.0458440320217905
Herbal tea (ukb-b-13344) Chondromalacia rs142302835 0.280205522407811 0.126408938958924 0.0266463970046241
Herbal tea (ukb-b-13344) Chondromalacia rs6006177 -0.286565305761214 0.0941179342883476 0.002328760559107
Herbal tea (ukb-b-13344) Chondromalacia rs73788078 -0.247262857668599 0.110635753059159 0.0254221262262308
Herbal tea (ukb-b-13344) Chondromalacia All - Inverse variance weighted -0.0179284647407221 0.0085553167991554 0.0361182822426596
Orange (ukb-b-13520) Chondromalacia All - Inverse variance weighted 3.22104623034332 1.49735586634648 0.031463879458696
Sweetcorn (ukb-b-13567) Chondromalacia All - MR Egger -4.71920347321584 2.2386631658277 0.0493065464103745
Other sweets (ukb-b-139) Chondromalacia All - Inverse variance weighted 1.90817508141915 0.908052392728057 0.0356064684282537
Salted nuts (ukb-b-15960) Chondromalacia rs144425541 -20.1911940995997 7.26121055732775 0.0054243081451504
Salted nuts (ukb-b-15960) Chondromalacia rs73085383 -22.1104421014185 9.79165211973423 0.0239399829728218
Salted nuts (ukb-b-15960) Chondromalacia All - MR Egger -5.47420110812255 2.49923121033321 0.0399239434153987
Other vegetarian alternative (ukb-b-16150) Chondromalacia All - Inverse variance weighted -4.68300067450583 2.24220032049443 0.036746112486126
Other fruit (ukb-b-18659) Chondromalacia All - Inverse variance weighted 2.88955972072117 1.22136749197683 0.0179892307129658
Low calorie drink (ukb-b-19703) Chondromalacia rs13429737 7.89866285659472 2.71871521142618 0.003669100644358
Low calorie drink (ukb-b-19703) Chondromalacia rs73523164 5.42489171760197 2.58933939017159 0.036163244846807
Low calorie drink (ukb-b-19703) Chondromalacia rs890797 6.97176330441902 3.03081948087772 0.0214318040450344
Low calorie drink (ukb-b-19703) Chondromalacia All - Inverse variance weighted 1.60515683206714 0.621094024774835 0.0097547934564203
Cheesy biscuits (ukb-b-19847) Chondromalacia rs61948341 -35.4492180629911 11.8891007196775 0.0028669318737688
Cheesy biscuits (ukb-b-19847) Chondromalacia All - Inverse variance weighted -4.04906674860909 2.00687143114448 0.0436327837140162
Vegetarian sausages/burgers (ukb-b-3383) Chondromalacia rs115183692 41.1024650951079 20.6936698983431 0.0470073774854338
Vegetarian sausages/burgers (ukb-b-3383) Chondromalacia rs116225626 14.5215045230916 7.35333015923398 0.0482885622133021
Vegetarian sausages/burgers (ukb-b-3383) Chondromalacia rs184522870 80.0567060691741 23.9166494155135 0.0008159662538337
Vegetarian sausages/burgers (ukb-b-3383) Chondromalacia All - MR Egger 6.07431449330993 2.94734853946999 0.0475134593904862
Turnip/swede (ukb-b-5008) Chondromalacia All - MR Egger 5.28301229368982 2.47414527215006 0.0475856512146828
Cucumber (ukb-b-588) Chondromalacia rs117632321 5.7080346792496 2.5568599278332 0.0255859404560149
Cucumber (ukb-b-588) Chondromalacia All - MR Egger 3.3230558017133 1.16756028271523 0.0122615223056383
Crumble (ukb-b-7641) Chondromalacia rs76702874 22.6178405411628 9.39246545483044 0.0160365152913143
Crumble (ukb-b-7641) Chondromalacia All - Inverse variance weighted 3.08555197672726 1.53818545470171 0.0448595806382246
Yogurt (ukb-b-7753) Chondromalacia rs149870452 7.84194886035085 3.18914166323942 0.0139342931565605
Yogurt (ukb-b-7753) Chondromalacia rs392542 5.71870677668578 2.66410717739669 0.0318271046836942
Yogurt (ukb-b-7753) Chondromalacia All - Inverse variance weighted 2.26149557759866 1.08587966493505 0.0372841215075543