ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Infection of intervertebral disc (pyogenic) (finn-b-M13_DISCINFECTION)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Beetroot (ukb-b-11880) (👉 📊) Infection of intervertebral disc (pyogenic) Simple mode 10 -13.87096589 4.920968265 0.020088054
Other alcohol (ukb-b-12901) (👉 📊) Infection of intervertebral disc (pyogenic) MR Egger 43 10.41875138 4.396938597 0.022599188
Cottage cheese (ukb-b-14171) (👉 📊) Infection of intervertebral disc (pyogenic) Simple mode 24 -23.79210016 11.37143305 0.047646291
Salted nuts (ukb-b-15960) (👉 📊) Infection of intervertebral disc (pyogenic) Inverse variance weighted 23 5.358275111 2.666491654 0.044485719
Low calorie hot chocolate (ukb-b-1795) (👉 📊) Infection of intervertebral disc (pyogenic) Inverse variance weighted 24 -6.917329323 3.39413205 0.041547334
Indian snacks (ukb-b-282) (👉 📊) Infection of intervertebral disc (pyogenic) Simple mode 24 -12.39478258 5.927443929 0.047762048
Sweet biscuits (ukb-b-3646) (👉 📊) Infection of intervertebral disc (pyogenic) Inverse variance weighted 11 2.178490646 0.84458215 0.009898044
Fresh fruit (ukb-b-3881) (👉 📊) Infection of intervertebral disc (pyogenic) MR Egger 141 -11.16912568 5.294526979 0.036688708
Fresh fruit (ukb-b-3881) (👉 📊) Infection of intervertebral disc (pyogenic) Inverse variance weighted 141 -3.030054161 1.515111101 0.045512241
Whole egg (ukb-b-4075) (👉 📊) Infection of intervertebral disc (pyogenic) Weighted median 6 6.756288928 2.850087236 0.017761395
Whole egg (ukb-b-4075) (👉 📊) Infection of intervertebral disc (pyogenic) Inverse variance weighted 6 7.172037595 2.338198358 0.002159767
Other cheese (ukb-b-4088) (👉 📊) Infection of intervertebral disc (pyogenic) MR Egger 17 -33.87146686 11.57406664 0.01041917
Other cheese (ukb-b-4088) (👉 📊) Infection of intervertebral disc (pyogenic) Weighted median 17 -14.5355113 5.908248407 0.013885708
Other cheese (ukb-b-4088) (👉 📊) Infection of intervertebral disc (pyogenic) Weighted mode 17 -15.4261326 7.090895345 0.044928775
Dairy smoothie (ukb-b-4955) (👉 📊) Infection of intervertebral disc (pyogenic) Inverse variance weighted 18 4.199248023 2.095642771 0.045091538
Courgette (ukb-b-7420) (👉 📊) Infection of intervertebral disc (pyogenic) Weighted median 19 6.500065243 2.980327107 0.029184116
Squash (ukb-b-8793) (👉 📊) Infection of intervertebral disc (pyogenic) MR Egger 18 8.910669029 3.277238183 0.015170957
Chocolate sweet (ukb-b-9835) (👉 📊) Infection of intervertebral disc (pyogenic) Simple mode 20 -6.863342405 3.070207491 0.037586465

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other alcohol (ukb-b-12901) Infection of intervertebral disc (pyogenic) rs117197531 26.3872184117284 12.7994668920456 0.0392470440204806
Other alcohol (ukb-b-12901) Infection of intervertebral disc (pyogenic) rs117476691 33.610500745612 15.8053926450518 0.0334598953673669
Other alcohol (ukb-b-12901) Infection of intervertebral disc (pyogenic) rs145439530 25.3610140242265 10.5353436736937 0.0160739650355101
Other alcohol (ukb-b-12901) Infection of intervertebral disc (pyogenic) rs7091162 -36.9927852580304 16.9773652150381 0.0293355783114538
Other alcohol (ukb-b-12901) Infection of intervertebral disc (pyogenic) All - MR Egger 10.4187513812435 4.39693859692981 0.0225991875211356
Salted nuts (ukb-b-15960) Infection of intervertebral disc (pyogenic) rs10845793 24.5636617171578 12.4810370983313 0.0490589974925776
Salted nuts (ukb-b-15960) Infection of intervertebral disc (pyogenic) rs146665115 15.1422409092022 7.06474682431395 0.0320848252711846
Salted nuts (ukb-b-15960) Infection of intervertebral disc (pyogenic) rs75342409 36.3688746155085 11.8574507328289 0.0021609241729825
Salted nuts (ukb-b-15960) Infection of intervertebral disc (pyogenic) All - Inverse variance weighted 5.35827511148784 2.66649165421565 0.0444857187280644
Low calorie hot chocolate (ukb-b-1795) Infection of intervertebral disc (pyogenic) rs146704655 170.668208081707 82.5371815878595 0.0386613138921646
Low calorie hot chocolate (ukb-b-1795) Infection of intervertebral disc (pyogenic) All - Inverse variance weighted -6.9173293229192 3.39413204950915 0.0415473339743511
Indian snacks (ukb-b-282) Infection of intervertebral disc (pyogenic) rs72696787 46.2787009387189 17.0526797068111 0.0066502904337563
Sweet biscuits (ukb-b-3646) Infection of intervertebral disc (pyogenic) rs60129519 6.25384161112651 2.74667662974703 0.0227936420339338
Sweet biscuits (ukb-b-3646) Infection of intervertebral disc (pyogenic) All - Inverse variance weighted 2.1784906458627 0.844582149915064 0.0098980439446118
Fresh fruit (ukb-b-3881) Infection of intervertebral disc (pyogenic) rs10459965 59.4421235395358 23.0641504856209 0.0099589371912676
Fresh fruit (ukb-b-3881) Infection of intervertebral disc (pyogenic) rs11032362 -54.474739568624 21.8754286728691 0.0127662244538131
Fresh fruit (ukb-b-3881) Infection of intervertebral disc (pyogenic) rs1172553 -63.6069812540401 27.5113122171946 0.0207760259921927
Fresh fruit (ukb-b-3881) Infection of intervertebral disc (pyogenic) rs133377 -45.5950702135203 20.3749961897153 0.0252344086523626
Fresh fruit (ukb-b-3881) Infection of intervertebral disc (pyogenic) rs62109907 -60.0950679297441 26.1403094764521 0.0215082056982051
Fresh fruit (ukb-b-3881) Infection of intervertebral disc (pyogenic) rs7124442 -47.4126230488298 21.5663318750385 0.0279166553752235
Fresh fruit (ukb-b-3881) Infection of intervertebral disc (pyogenic) rs7555067 -47.529651962523 21.3684456402315 0.0261288383627433
Fresh fruit (ukb-b-3881) Infection of intervertebral disc (pyogenic) rs7869969 38.2695199659592 16.9014903440821 0.0235575774632371
Fresh fruit (ukb-b-3881) Infection of intervertebral disc (pyogenic) All - Inverse variance weighted -3.03005416051359 1.51511110056632 0.0455122414757417
Fresh fruit (ukb-b-3881) Infection of intervertebral disc (pyogenic) All - MR Egger -11.1691256774716 5.29452697887507 0.0366887084013709
Whole egg (ukb-b-4075) Infection of intervertebral disc (pyogenic) rs811082 9.8217473830599 4.88150946232922 0.0442166904723059
Whole egg (ukb-b-4075) Infection of intervertebral disc (pyogenic) All - Inverse variance weighted 7.17203759542744 2.33819835756064 0.0021597667992984
Other cheese (ukb-b-4088) Infection of intervertebral disc (pyogenic) rs116592084 -20.3616663006077 10.0593015594114 0.0429533803389947
Other cheese (ukb-b-4088) Infection of intervertebral disc (pyogenic) All - MR Egger -33.8714668597894 11.574066643181 0.0104191702873704
Dairy smoothie (ukb-b-4955) Infection of intervertebral disc (pyogenic) All - Inverse variance weighted 4.19924802311993 2.09564277077405 0.0450915379891597
Courgette (ukb-b-7420) Infection of intervertebral disc (pyogenic) rs12224049 14.7449195216878 7.11833226065747 0.0383213511903892
Courgette (ukb-b-7420) Infection of intervertebral disc (pyogenic) rs6859913 -12.6457608606441 5.92513558048651 0.0328217660382183
Courgette (ukb-b-7420) Infection of intervertebral disc (pyogenic) rs7969412 19.676178029478 9.99540163121082 0.0490078921214108
Squash (ukb-b-8793) Infection of intervertebral disc (pyogenic) rs10097265 -15.368805184455 5.72135651517376 0.0072266136044611
Squash (ukb-b-8793) Infection of intervertebral disc (pyogenic) rs116063249 10.5094890969647 4.81760196066109 0.0291481350450236
Squash (ukb-b-8793) Infection of intervertebral disc (pyogenic) All - MR Egger 8.91066902933401 3.27723818291502 0.0151709570707155
Chocolate sweet (ukb-b-9835) Infection of intervertebral disc (pyogenic) rs115654287 -8.06167654335194 3.92957827512801 0.0402146476344393
Chocolate sweet (ukb-b-9835) Infection of intervertebral disc (pyogenic) rs148822130 14.4987985191699 7.37758378153638 0.0493852782595474
Chocolate sweet (ukb-b-9835) Infection of intervertebral disc (pyogenic) rs7959426 -14.5973830109941 5.73269693827711 0.0108859783155104