ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sweets (ukb-b-10217) (👉 📊) Ankylosing hyperostosis [Forestier] Inverse variance weighted 21 -1.967030731 0.987728225 0.046429284
Oily fish (ukb-b-10546) (👉 📊) Ankylosing hyperostosis [Forestier] Inverse variance weighted 15 -4.383337485 2.210341519 0.047355795
Oily fish (ukb-b-10546) (👉 📊) Ankylosing hyperostosis [Forestier] Simple mode 15 -10.75556187 4.870542689 0.044404705
Lobster/crab (ukb-b-14746) (👉 📊) Ankylosing hyperostosis [Forestier] Inverse variance weighted 54 8.929254298 4.347880432 0.040004464
Ice-cream (ukb-b-17189) (👉 📊) Ankylosing hyperostosis [Forestier] MR Egger 16 -8.189506875 3.810732484 0.049603429
Quorn (ukb-b-19069) (👉 📊) Ankylosing hyperostosis [Forestier] MR Egger 25 -11.54660333 4.758143124 0.023480644
Butternut squash (ukb-b-20341) (👉 📊) Ankylosing hyperostosis [Forestier] MR Egger 16 12.66470293 5.192006451 0.028628518
Cake (ukb-b-3433) (👉 📊) Ankylosing hyperostosis [Forestier] Inverse variance weighted 10 -3.579385283 1.818215058 0.048996064
Sweet biscuits (ukb-b-3646) (👉 📊) Ankylosing hyperostosis [Forestier] Weighted median 11 -2.426105777 0.97681296 0.013002701
Oat crunch (ukb-b-5186) (👉 📊) Ankylosing hyperostosis [Forestier] Weighted median 13 11.10944841 5.236517999 0.033876931
Olives (ukb-b-5232) (👉 📊) Ankylosing hyperostosis [Forestier] Inverse variance weighted 23 6.155603518 2.452049606 0.012059751
Banana (ukb-b-5362) (👉 📊) Ankylosing hyperostosis [Forestier] MR Egger 16 5.629925695 2.459699517 0.038146598
Yorkshire pudding (ukb-b-5605) (👉 📊) Ankylosing hyperostosis [Forestier] MR Egger 15 12.36679681 5.305414806 0.036496492
Doughnut (ukb-b-6214) (👉 📊) Ankylosing hyperostosis [Forestier] Inverse variance weighted 31 -7.045389852 3.230620443 0.029197003

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sweets (ukb-b-10217) Ankylosing hyperostosis [Forestier] All - Inverse variance weighted -1.96703073140829 0.987728224857193 0.0464292843010352
Oily fish (ukb-b-10546) Ankylosing hyperostosis [Forestier] rs114296824 -16.5064747284438 7.09677505015541 0.0200232421428099
Oily fish (ukb-b-10546) Ankylosing hyperostosis [Forestier] rs188626385 48.4883909268245 22.949134161027 0.0346124415320698
Oily fish (ukb-b-10546) Ankylosing hyperostosis [Forestier] rs61915889 -11.0539077752534 5.39842007628655 0.0405973414877944
Oily fish (ukb-b-10546) Ankylosing hyperostosis [Forestier] All - Inverse variance weighted -4.38333748486084 2.21034151851868 0.0473557948009104
Lobster/crab (ukb-b-14746) Ankylosing hyperostosis [Forestier] rs116918010 87.5853586122068 37.5971740012967 0.0198287345313754
Lobster/crab (ukb-b-14746) Ankylosing hyperostosis [Forestier] rs74919141 68.0618215826746 32.8247085106432 0.0381263701872708
Lobster/crab (ukb-b-14746) Ankylosing hyperostosis [Forestier] All - Inverse variance weighted 8.92925429832352 4.34788043168608 0.0400044635732024
Ice-cream (ukb-b-17189) Ankylosing hyperostosis [Forestier] All - MR Egger -8.18950687524749 3.81073248375241 0.0496034294543909
Quorn (ukb-b-19069) Ankylosing hyperostosis [Forestier] rs117401530 -24.1767682460571 10.68091601193 0.0236019166921747
Quorn (ukb-b-19069) Ankylosing hyperostosis [Forestier] All - MR Egger -11.5466033281038 4.75814312402423 0.0234806442344161
Butternut squash (ukb-b-20341) Ankylosing hyperostosis [Forestier] All - MR Egger 12.6647029304457 5.19200645093595 0.0286285181536563
Cake (ukb-b-3433) Ankylosing hyperostosis [Forestier] All - Inverse variance weighted -3.57938528263098 1.81821505828133 0.0489960644117845
Sweet biscuits (ukb-b-3646) Ankylosing hyperostosis [Forestier] rs117635565 -5.35781116338751 2.29964178785287 0.0198142932577007
Sweet biscuits (ukb-b-3646) Ankylosing hyperostosis [Forestier] rs62174398 5.52963166005499 2.2518536424632 0.014065311527419
Olives (ukb-b-5232) Ankylosing hyperostosis [Forestier] rs10256030 30.8457789470795 8.18097340448473 0.0001629671967571
Olives (ukb-b-5232) Ankylosing hyperostosis [Forestier] All - Inverse variance weighted 6.15560351821524 2.45204960588675 0.0120597511199265
Banana (ukb-b-5362) Ankylosing hyperostosis [Forestier] rs1010086 -11.8235249964918 3.72034736295905 0.0014825886210409
Banana (ukb-b-5362) Ankylosing hyperostosis [Forestier] rs76722032 5.62334492964328 2.72748177104582 0.0392329619401866
Banana (ukb-b-5362) Ankylosing hyperostosis [Forestier] All - MR Egger 5.62992569509346 2.45969951706118 0.0381465980200434
Yorkshire pudding (ukb-b-5605) Ankylosing hyperostosis [Forestier] rs112606901 23.5591195423937 9.96186614534308 0.0180334622857228
Yorkshire pudding (ukb-b-5605) Ankylosing hyperostosis [Forestier] rs77056729 22.8180230051955 10.1299997731243 0.0242894557323547
Yorkshire pudding (ukb-b-5605) Ankylosing hyperostosis [Forestier] All - MR Egger 12.3667968108448 5.30541480619057 0.0364964922713842
Doughnut (ukb-b-6214) Ankylosing hyperostosis [Forestier] rs10922656 -47.0591520974138 18.9757148088154 0.0131394434424976
Doughnut (ukb-b-6214) Ankylosing hyperostosis [Forestier] rs116455686 44.8885637301262 21.255866240788 0.0347018900282904
Doughnut (ukb-b-6214) Ankylosing hyperostosis [Forestier] rs80025943 -27.2462586394563 11.3346589794576 0.0162256264924917
Doughnut (ukb-b-6214) Ankylosing hyperostosis [Forestier] All - Inverse variance weighted -7.04538985160441 3.2306204425556 0.029197003449526