Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP)

Mendelian Randomization Results

Intake (exposure)	Outcome	Method	Number of SNPs	b	se	P-value
Poultry (ukb-b-16010) (👉 📊)	Juvenile osteochondrosis	Inverse variance weighted	9	1.89125339	0.936930429	0.043532627
Hot chocolate (ukb-b-16449) (👉 📊)	Juvenile osteochondrosis	MR Egger	18	8.855020998	3.097627144	0.011375547
Low fat hard cheese (ukb-b-18079) (👉 📊)	Juvenile osteochondrosis	MR Egger	16	6.915464508	2.267655796	0.008656505
Grapefruit (ukb-b-18758) (👉 📊)	Juvenile osteochondrosis	MR Egger	16	-9.465547339	3.874278901	0.028414294
Quorn (ukb-b-19069) (👉 📊)	Juvenile osteochondrosis	Inverse variance weighted	25	3.326037151	1.61771417	0.039781514
Melon (ukb-b-19862) (👉 📊)	Juvenile osteochondrosis	Weighted median	16	-3.592388647	1.68116691	0.032610816
Melon (ukb-b-19862) (👉 📊)	Juvenile osteochondrosis	Inverse variance weighted	16	-3.627402216	1.275724716	0.004463429
Green bean (ukb-b-2299) (👉 📊)	Juvenile osteochondrosis	MR Egger	17	-3.39862294	1.543091755	0.043688588
Fizzy drink (ukb-b-2832) (👉 📊)	Juvenile osteochondrosis	MR Egger	12	6.480862481	2.511702573	0.027403766
Crumbed or deep-fried poultry (ukb-b-39) (👉 📊)	Juvenile osteochondrosis	Inverse variance weighted	12	-3.295121469	1.506330897	0.028704948
Lamb (ukb-b-530) (👉 📊)	Juvenile osteochondrosis	MR Egger	13	5.128441513	1.825989059	0.017011582
Lamb (ukb-b-530) (👉 📊)	Juvenile osteochondrosis	Weighted mode	13	4.169469096	1.714332056	0.031609576
Scone (ukb-b-5627) (👉 📊)	Juvenile osteochondrosis	MR Egger	10	10.62913605	4.554362274	0.047874121
Scone (ukb-b-5627) (👉 📊)	Juvenile osteochondrosis	Inverse variance weighted	10	3.815907823	1.755260097	0.029706317
Couscous (ukb-b-758) (👉 📊)	Juvenile osteochondrosis	Weighted median	17	6.965645208	3.450117838	0.043491519
Couscous (ukb-b-758) (👉 📊)	Juvenile osteochondrosis	Inverse variance weighted	17	5.316633809	2.531972742	0.035746527
Other grain (ukb-b-8765) (👉 📊)	Juvenile osteochondrosis	Inverse variance weighted	70	-3.820528795	1.839458341	0.037802873

Mendelian Randomization Results (Single SNP)

Intake (exposure)	Outcome	SNP	b	se	P-value
Poultry (ukb-b-16010)	Juvenile osteochondrosis	All - Inverse variance weighted	1.89125338969569	0.936930428757898	0.0435326274568662
Hot chocolate (ukb-b-16449)	Juvenile osteochondrosis	rs116341761	47.2740762142216	23.9839203579754	0.048715438973253
Hot chocolate (ukb-b-16449)	Juvenile osteochondrosis	rs142532384	8.43702298903742	4.07280632776724	0.0383074030988668
Hot chocolate (ukb-b-16449)	Juvenile osteochondrosis	rs59246261	-14.8219517250265	5.8481170071533	0.0112613468657887
Hot chocolate (ukb-b-16449)	Juvenile osteochondrosis	rs9509220	-16.1416017986868	5.7507815509195	0.0050027975128074
Hot chocolate (ukb-b-16449)	Juvenile osteochondrosis	All - MR Egger	8.85502099838827	3.0976271444128	0.0113755473681966
Low fat hard cheese (ukb-b-18079)	Juvenile osteochondrosis	rs117864679	9.78685022549252	3.9686684073107	0.0136620384004329
Low fat hard cheese (ukb-b-18079)	Juvenile osteochondrosis	All - MR Egger	6.91546450784643	2.26765579552301	0.0086565051194112
Grapefruit (ukb-b-18758)	Juvenile osteochondrosis	rs72861422	-12.7198273386018	6.08910444209196	0.036712333474458
Grapefruit (ukb-b-18758)	Juvenile osteochondrosis	All - MR Egger	-9.46554733867268	3.87427890110274	0.028414294179157
Quorn (ukb-b-19069)	Juvenile osteochondrosis	rs150548333	11.0011494131666	4.10994295114467	0.0074347660177646
Quorn (ukb-b-19069)	Juvenile osteochondrosis	All - Inverse variance weighted	3.32603715084667	1.61771416994191	0.0397815141672975
Melon (ukb-b-19862)	Juvenile osteochondrosis	rs62019153	-14.4942726660178	5.90701504828929	0.0141379590004402
Melon (ukb-b-19862)	Juvenile osteochondrosis	All - Inverse variance weighted	-3.6274022164954	1.2757247161241	0.0044634293562962
Green bean (ukb-b-2299)	Juvenile osteochondrosis	rs146548702	-6.70326904319919	3.3956832268823	0.0483753691671712
Green bean (ukb-b-2299)	Juvenile osteochondrosis	All - MR Egger	-3.39862293998197	1.54309175538682	0.0436885875821004
Fizzy drink (ukb-b-2832)	Juvenile osteochondrosis	All - MR Egger	6.48086248074588	2.51170257287911	0.0274037656701565
Crumbed or deep-fried poultry (ukb-b-39)	Juvenile osteochondrosis	All - Inverse variance weighted	-3.29512146851813	1.50633089679565	0.0287049476284317
Lamb (ukb-b-530)	Juvenile osteochondrosis	rs142252464	4.59409850297969	1.67800702242438	0.0061845976337271
Lamb (ukb-b-530)	Juvenile osteochondrosis	All - MR Egger	5.12844151290992	1.82598905932163	0.0170115822922367
Scone (ukb-b-5627)	Juvenile osteochondrosis	rs115147089	9.70802807363172	3.61694268300191	0.0072737847563319
Scone (ukb-b-5627)	Juvenile osteochondrosis	All - Inverse variance weighted	3.81590782322045	1.75526009706629	0.0297063173017166
Scone (ukb-b-5627)	Juvenile osteochondrosis	All - MR Egger	10.6291360538774	4.55436227439419	0.0478741212601957
Couscous (ukb-b-758)	Juvenile osteochondrosis	rs11839514	21.3133769878391	9.72871842843779	0.0284684963000664
Couscous (ukb-b-758)	Juvenile osteochondrosis	All - Inverse variance weighted	5.31663380901209	2.53197274240721	0.0357465270808372
Other grain (ukb-b-8765)	Juvenile osteochondrosis	rs144535592	-16.9264670707441	7.02300798485473	0.0159461847101246
Other grain (ukb-b-8765)	Juvenile osteochondrosis	rs7145793	97.2023903961077	42.6913110159183	0.0227942345889143
Other grain (ukb-b-8765)	Juvenile osteochondrosis	rs7173652	-43.0637828902053	19.1486430637829	0.0245175313742342
Other grain (ukb-b-8765)	Juvenile osteochondrosis	rs76934814	-60.3537120203411	26.0206269323644	0.0203702976889012
Other grain (ukb-b-8765)	Juvenile osteochondrosis	All - Inverse variance weighted	-3.82052879529577	1.83945834108266	0.0378028727930343