ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Osteopathies and chondropathies (finn-b-M13_OSTEOCHONDRO)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Salted peanuts (ukb-b-1099) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 13 -0.903784442 0.385158842 0.018949449
Satsuma (ukb-b-11563) (👉 📊) Osteopathies and chondropathies MR Egger 18 -0.811674268 0.361050945 0.039018964
Chocolate-covered raisin (ukb-b-1160) (👉 📊) Osteopathies and chondropathies Weighted median 51 -0.852559673 0.372196415 0.021985538
Chocolate-covered raisin (ukb-b-1160) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 51 -0.511576201 0.249609384 0.040412556
Avocado (ukb-b-12236) (👉 📊) Osteopathies and chondropathies MR Egger 24 -1.646364673 0.584992011 0.010101037
Avocado (ukb-b-12236) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 24 -0.664526733 0.307629206 0.030760681
Sweetcorn (ukb-b-13567) (👉 📊) Osteopathies and chondropathies Weighted median 20 -0.634945102 0.313080442 0.042554392
Sweetcorn (ukb-b-13567) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 20 -0.610719687 0.225062607 0.006656558
Other sweets (ukb-b-139) (👉 📊) Osteopathies and chondropathies MR Egger 26 0.873224469 0.348205324 0.019316251
Other sweets (ukb-b-139) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 26 0.421604037 0.201529282 0.036436395
Celery (ukb-b-14145) (👉 📊) Osteopathies and chondropathies MR Egger 15 -0.968382519 0.336085362 0.012859827
Salted nuts (ukb-b-15960) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 23 -0.609515204 0.308172817 0.047947243
Poultry (ukb-b-16010) (👉 📊) Osteopathies and chondropathies Weighted median 9 0.616423101 0.314226389 0.049795496
Poultry (ukb-b-16010) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 9 0.554797867 0.241459472 0.02157971
Sprouts (ukb-b-16077) (👉 📊) Osteopathies and chondropathies MR Egger 13 1.597121479 0.694413293 0.042035025
Bran cereal (ukb-b-19498) (👉 📊) Osteopathies and chondropathies Weighted median 4 -1.206278346 0.509067395 0.017808072
Bran cereal (ukb-b-19498) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 4 -0.946472666 0.440295298 0.03158437
Milk-based pudding (ukb-b-20554) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 17 0.770294361 0.375080207 0.040006766
Spirits (ukb-b-3751) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 25 -0.301552887 0.149644547 0.04389126
Pork (ukb-b-5640) (👉 📊) Osteopathies and chondropathies MR Egger 82 -1.572492889 0.666389095 0.020725854
Tea (ukb-b-6066) (👉 📊) Osteopathies and chondropathies Weighted mode 137 0.501921654 0.245795718 0.043081683
Watercress (ukb-b-6181) (👉 📊) Osteopathies and chondropathies Weighted median 12 1.338644368 0.523632125 0.010574335
Watercress (ukb-b-6181) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 12 0.891401038 0.441524727 0.043496021
Watercress (ukb-b-6181) (👉 📊) Osteopathies and chondropathies Weighted mode 12 1.572946641 0.628373103 0.02933876
Processed meat (ukb-b-6324) (👉 📊) Osteopathies and chondropathies Weighted median 125 -0.397613885 0.187705666 0.034151034
Fortified wine (ukb-b-9524) (👉 📊) Osteopathies and chondropathies Inverse variance weighted 20 -0.913741348 0.455536745 0.044871559
Sweet potato (ukb-b-9686) (👉 📊) Osteopathies and chondropathies Weighted median 24 0.991799885 0.481456097 0.039398476

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Salted peanuts (ukb-b-1099) Osteopathies and chondropathies rs144387937 -3.76642140838967 1.84668019555159 0.0413938267577404
Salted peanuts (ukb-b-1099) Osteopathies and chondropathies All - Inverse variance weighted -0.903784441529828 0.385158841784955 0.018949449019115
Satsuma (ukb-b-11563) Osteopathies and chondropathies rs117352891 -1.1674220574097 0.443539591361885 0.0084869301134861
Satsuma (ukb-b-11563) Osteopathies and chondropathies rs55776785 1.96949493850005 0.952432785457712 0.038653458450555
Satsuma (ukb-b-11563) Osteopathies and chondropathies All - MR Egger -0.811674267528433 0.361050945163443 0.0390189637513295
Chocolate-covered raisin (ukb-b-1160) Osteopathies and chondropathies rs147824007 11.4548465930808 4.39353401514186 0.0091284524128852
Chocolate-covered raisin (ukb-b-1160) Osteopathies and chondropathies All - Inverse variance weighted -0.511576201137403 0.249609384303991 0.0404125559419094
Avocado (ukb-b-12236) Osteopathies and chondropathies rs76118425 -3.85445234771188 1.95067846086779 0.0481599037166043
Avocado (ukb-b-12236) Osteopathies and chondropathies All - Inverse variance weighted -0.664526733209192 0.307629205596706 0.0307606808547427
Avocado (ukb-b-12236) Osteopathies and chondropathies All - MR Egger -1.64636467286115 0.584992010979527 0.010101036912362
Sweetcorn (ukb-b-13567) Osteopathies and chondropathies rs2540716 -2.23855799555786 1.03766490419088 0.0309820345467385
Sweetcorn (ukb-b-13567) Osteopathies and chondropathies All - Inverse variance weighted -0.610719687264961 0.225062607066537 0.0066565584698331
Other sweets (ukb-b-139) Osteopathies and chondropathies rs78668444 2.80628294119336 1.05464028673685 0.0077934161261437
Other sweets (ukb-b-139) Osteopathies and chondropathies All - Inverse variance weighted 0.421604036690945 0.201529282225374 0.0364363947736404
Other sweets (ukb-b-139) Osteopathies and chondropathies All - MR Egger 0.873224469158234 0.348205324256981 0.0193162506943172
Celery (ukb-b-14145) Osteopathies and chondropathies rs139795526 -2.55576247193615 0.858077939000902 0.0028968800175528
Celery (ukb-b-14145) Osteopathies and chondropathies rs3110454 1.6984482359299 0.860253002613846 0.0483409394676693
Celery (ukb-b-14145) Osteopathies and chondropathies All - MR Egger -0.968382519015346 0.336085362419646 0.0128598273111855
Salted nuts (ukb-b-15960) Osteopathies and chondropathies rs10996983 4.30212024603861 2.14908486119835 0.0453021322433963
Salted nuts (ukb-b-15960) Osteopathies and chondropathies rs144425541 -3.40329560924071 1.57465916248451 0.0306729200049368
Salted nuts (ukb-b-15960) Osteopathies and chondropathies rs79900875 -5.61597619496658 2.8603759351229 0.0496032013348541
Salted nuts (ukb-b-15960) Osteopathies and chondropathies All - Inverse variance weighted -0.609515203882645 0.308172816507064 0.0479472426078411
Poultry (ukb-b-16010) Osteopathies and chondropathies rs75615794 1.08762045654286 0.422677144248885 0.0100771482958953
Poultry (ukb-b-16010) Osteopathies and chondropathies All - Inverse variance weighted 0.554797866828563 0.241459471582906 0.0215797095392747
Sprouts (ukb-b-16077) Osteopathies and chondropathies All - MR Egger 1.59712147944617 0.694413292947351 0.0420350249339215
Bran cereal (ukb-b-19498) Osteopathies and chondropathies rs8176599 -1.36768007409307 0.469891743298368 0.0036070316546628
Bran cereal (ukb-b-19498) Osteopathies and chondropathies All - Inverse variance weighted -0.946472666241635 0.44029529760096 0.0315843701781531
Milk-based pudding (ukb-b-20554) Osteopathies and chondropathies All - Inverse variance weighted 0.770294361300951 0.375080206597668 0.0400067658017368
Spirits (ukb-b-3751) Osteopathies and chondropathies rs76296599 -1.07906076409446 0.488048475363334 0.0270378824441949
Spirits (ukb-b-3751) Osteopathies and chondropathies rs7746271 1.70268500327439 0.839215115573989 0.042468300116272
Spirits (ukb-b-3751) Osteopathies and chondropathies All - Inverse variance weighted -0.301552887070061 0.149644546853008 0.0438912596574874
Pork (ukb-b-5640) Osteopathies and chondropathies rs11635385 7.30404420091975 2.27774200690703 0.0013426511137342
Pork (ukb-b-5640) Osteopathies and chondropathies rs1323058 -5.93961615737953 2.13772062156257 0.0054613705011741
Pork (ukb-b-5640) Osteopathies and chondropathies rs61791721 6.28663240907557 2.40056662879634 0.0088236591746644
Pork (ukb-b-5640) Osteopathies and chondropathies All - MR Egger -1.57249288924243 0.666389094919401 0.0207258542789273
Tea (ukb-b-6066) Osteopathies and chondropathies rs10244642 3.7107738443995 1.56873121775123 0.0180075986062765
Tea (ukb-b-6066) Osteopathies and chondropathies rs11752836 3.18413720736694 1.42924340557948 0.0258906460004691
Tea (ukb-b-6066) Osteopathies and chondropathies rs1950709 -3.82271786617613 1.47543496589254 0.0095722774484179
Tea (ukb-b-6066) Osteopathies and chondropathies rs2027239 -3.03361782775156 1.29103651789008 0.0187858374339357
Tea (ukb-b-6066) Osteopathies and chondropathies rs2472297 0.725462224413397 0.333675131642338 0.0296933236740624
Tea (ukb-b-6066) Osteopathies and chondropathies rs35970998 2.59407425928241 1.31266408301038 0.0481332081474505
Watercress (ukb-b-6181) Osteopathies and chondropathies rs114107092 -3.0172806597863 1.45951518465359 0.0387042865145395
Watercress (ukb-b-6181) Osteopathies and chondropathies rs191852210 2.12558804524842 0.632998365606991 0.0007851779680607
Watercress (ukb-b-6181) Osteopathies and chondropathies All - Inverse variance weighted 0.891401037568521 0.441524727368434 0.0434960213184441
Processed meat (ukb-b-6324) Osteopathies and chondropathies rs113443850 -4.30742194588503 1.54723360362167 0.0053701209612558
Processed meat (ukb-b-6324) Osteopathies and chondropathies rs11786089 3.90127531344729 1.39907804344317 0.0052959035414422
Processed meat (ukb-b-6324) Osteopathies and chondropathies rs16919108 3.48128807658834 1.68020500918673 0.0382708088934747
Processed meat (ukb-b-6324) Osteopathies and chondropathies rs4661151 3.38088264540507 1.46444649346423 0.0209634566558017
Processed meat (ukb-b-6324) Osteopathies and chondropathies rs4965927 3.54849776993579 1.54879184433662 0.0219553617352278
Processed meat (ukb-b-6324) Osteopathies and chondropathies rs59015823 -3.36681261583535 1.69149960747497 0.046543519445847
Processed meat (ukb-b-6324) Osteopathies and chondropathies rs62141888 3.23578004922225 1.23398391707628 0.0087358448835196
Processed meat (ukb-b-6324) Osteopathies and chondropathies rs6765179 -2.4685939985737 1.23037859611451 0.0448168477302909
Processed meat (ukb-b-6324) Osteopathies and chondropathies rs9365786 3.44774816135101 1.53033208206181 0.0242628581531735
Fortified wine (ukb-b-9524) Osteopathies and chondropathies rs113146569 -3.90174006267524 1.71119907636484 0.0226005437753925
Fortified wine (ukb-b-9524) Osteopathies and chondropathies rs4279116 -4.91327099620757 2.17747237331926 0.024044949905368
Fortified wine (ukb-b-9524) Osteopathies and chondropathies rs79482515 -4.28212465973337 2.15676694353319 0.0470958847263899
Fortified wine (ukb-b-9524) Osteopathies and chondropathies All - Inverse variance weighted -0.913741348180074 0.455536745270305 0.0448715589318368
Sweet potato (ukb-b-9686) Osteopathies and chondropathies rs142057497 4.85880629973888 2.10340771708183 0.0208898788941942