ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Osteomalacia (finn-b-M13_OSTEOMALACIA)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Chocolate-covered raisin (ukb-b-1160) (👉 📊) Osteomalacia MR Egger 51 11.80028288 5.768807665 0.046190469
Grape (ukb-b-12051) (👉 📊) Osteomalacia Inverse variance weighted 8 -4.164115353 2.000627625 0.037396897
Avocado (ukb-b-12236) (👉 📊) Osteomalacia Weighted median 24 -8.298539055 3.830365683 0.030271968
Other sweets (ukb-b-139) (👉 📊) Osteomalacia MR Egger 26 6.355318126 2.924694135 0.039879324
Other sweets (ukb-b-139) (👉 📊) Osteomalacia Weighted median 26 5.068102287 2.455057795 0.0389844
Other sweets (ukb-b-139) (👉 📊) Osteomalacia Inverse variance weighted 26 3.373223059 1.698660142 0.047053983
Lamb/mutton (ukb-b-14179) (👉 📊) Osteomalacia MR Egger 128 12.4703632 4.752630967 0.009767381
Milk (ukb-b-2966) (👉 📊) Osteomalacia MR Egger 20 -12.84647154 5.134127567 0.022207507
Vegetarian sausages/burgers (ukb-b-3383) (👉 📊) Osteomalacia Simple mode 34 -12.70831594 6.241421324 0.049829234
Olives (ukb-b-5232) (👉 📊) Osteomalacia Inverse variance weighted 23 -6.166236418 2.929500271 0.035302056
Coffee (ukb-b-5237) (👉 📊) Osteomalacia MR Egger 117 -6.959059285 2.790371278 0.01405458
Baguette (ukb-b-5277) (👉 📊) Osteomalacia Weighted median 13 5.88111256 2.839074951 0.03831312
Baguette (ukb-b-5277) (👉 📊) Osteomalacia Weighted mode 13 6.423377078 2.888875037 0.046148224
Sausage (ukb-b-5847) (👉 📊) Osteomalacia Weighted median 12 7.384799782 2.414990722 0.002228941
Sausage (ukb-b-5847) (👉 📊) Osteomalacia Inverse variance weighted 12 4.556956439 1.756000997 0.009456994
Sausage (ukb-b-5847) (👉 📊) Osteomalacia Weighted mode 12 7.83131537 3.472662511 0.045478709
Other egg (ukb-b-8266) (👉 📊) Osteomalacia Weighted median 21 -12.68745578 6.163523064 0.039544595
Other grain (ukb-b-8765) (👉 📊) Osteomalacia Simple mode 70 -29.44073429 11.29059862 0.011168346
Chocolate biscuits (ukb-b-9886) (👉 📊) Osteomalacia Weighted median 8 3.594780983 1.528371396 0.018671085

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Chocolate-covered raisin (ukb-b-1160) Osteomalacia rs118094512 58.9874290613264 26.9994067088494 0.0289058906168799
Chocolate-covered raisin (ukb-b-1160) Osteomalacia rs4124000 -53.7220184958823 18.779864429381 0.0042281615358583
Chocolate-covered raisin (ukb-b-1160) Osteomalacia rs74788010 34.9416704506595 14.9229466933508 0.0192078369765333
Chocolate-covered raisin (ukb-b-1160) Osteomalacia rs78266566 34.6756446569025 16.1466943236499 0.0317504505855243
Chocolate-covered raisin (ukb-b-1160) Osteomalacia rs79266273 35.8232941359894 16.4634841061866 0.0295609259607449
Chocolate-covered raisin (ukb-b-1160) Osteomalacia All - MR Egger 11.8002828835588 5.76880766540985 0.0461904690784619
Grape (ukb-b-12051) Osteomalacia rs117720571 -18.434505413338 6.6923241394056 0.0058768508889471
Grape (ukb-b-12051) Osteomalacia All - Inverse variance weighted -4.16411535302677 2.0006276245846 0.037396896569604
Avocado (ukb-b-12236) Osteomalacia rs28482137 32.1788273165693 11.1226555039728 0.0038147372876904
Avocado (ukb-b-12236) Osteomalacia rs62196418 -27.8806777895148 13.3271593326291 0.0364367674344147
Avocado (ukb-b-12236) Osteomalacia rs9288373 34.2835727263099 11.7971989799659 0.003659909658545
Other sweets (ukb-b-139) Osteomalacia rs76694902 12.4900706424522 5.72901191522906 0.029246793124817
Other sweets (ukb-b-139) Osteomalacia All - Inverse variance weighted 3.37322305910187 1.69866014245439 0.0470539828191371
Other sweets (ukb-b-139) Osteomalacia All - MR Egger 6.35531812602424 2.92469413478339 0.0398793239650942
Lamb/mutton (ukb-b-14179) Osteomalacia rs10118916 -48.3267611492246 18.375662577409 0.0085401701087048
Lamb/mutton (ukb-b-14179) Osteomalacia rs115687569 49.3626501025784 23.3742320828811 0.0347001317353108
Lamb/mutton (ukb-b-14179) Osteomalacia rs2055145 43.7648584395937 19.1628845184065 0.0223812541775087
Lamb/mutton (ukb-b-14179) Osteomalacia rs41282441 29.9329028790908 15.1778587404076 0.048593321940754
Lamb/mutton (ukb-b-14179) Osteomalacia rs4315028 48.1141371523213 18.8844302357298 0.0108398252381723
Lamb/mutton (ukb-b-14179) Osteomalacia rs4486004 -36.733618566296 17.9584023119286 0.0408071980937276
Lamb/mutton (ukb-b-14179) Osteomalacia All - MR Egger 12.4703631962434 4.75263096712734 0.009767381168005
Milk (ukb-b-2966) Osteomalacia All - MR Egger -12.8464715444621 5.13412756650629 0.022207506512079
Vegetarian sausages/burgers (ukb-b-3383) Osteomalacia rs116455648 48.9134688127723 21.7733118627909 0.0246728114214513
Vegetarian sausages/burgers (ukb-b-3383) Osteomalacia rs3214057 -54.3819591951666 25.21990903693 0.0310594139114186
Olives (ukb-b-5232) Osteomalacia All - Inverse variance weighted -6.16623641793617 2.92950027096358 0.0353020556126417
Coffee (ukb-b-5237) Osteomalacia rs1057868 -13.4931256234055 6.64130440230767 0.0421842270568458
Coffee (ukb-b-5237) Osteomalacia rs2126069 36.5576501693196 14.8041505948824 0.0135332668135675
Coffee (ukb-b-5237) Osteomalacia rs2472297 -8.97122494125343 3.24074472572024 0.0056356425792132
Coffee (ukb-b-5237) Osteomalacia rs4615895 27.3058799426347 12.7023150993649 0.0315807397879927
Coffee (ukb-b-5237) Osteomalacia rs56349356 -35.7062338996707 16.3655112004701 0.0291244700045203
Coffee (ukb-b-5237) Osteomalacia rs6030315 36.8652419329873 16.7428565531902 0.0276759766218931
Coffee (ukb-b-5237) Osteomalacia rs6062682 39.9791714880815 13.5192470878655 0.0031044265925241
Coffee (ukb-b-5237) Osteomalacia rs6544966 -34.9520671980029 16.6383605651671 0.0356680317576959
Coffee (ukb-b-5237) Osteomalacia rs6691876 40.8078179877456 14.6685497126318 0.005402603097024
Coffee (ukb-b-5237) Osteomalacia rs75347775 29.4725560744086 14.2482584398683 0.038592809806785
Coffee (ukb-b-5237) Osteomalacia All - MR Egger -6.95905928525667 2.79037127823021 0.014054579590562
Baguette (ukb-b-5277) Osteomalacia rs73101535 6.09964452740505 3.09699760808254 0.0488917118205133
Sausage (ukb-b-5847) Osteomalacia All - Inverse variance weighted 4.55695643873163 1.75600099743612 0.009456994326888
Other grain (ukb-b-8765) Osteomalacia rs138677842 135.268093685249 64.4398399234941 0.0358047689796311
Other grain (ukb-b-8765) Osteomalacia rs139141855 52.421029516367 26.2510920053276 0.0458351205302133
Other grain (ukb-b-8765) Osteomalacia rs7587553 147.436699247717 71.502599932098 0.0392099487348953
Chocolate biscuits (ukb-b-9886) Osteomalacia rs118143545 5.03664193304346 2.04033287228433 0.0135665744327826