ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | Method | Number of SNPs | b | se | P-value |
|---|---|---|---|---|---|---|
| Sweets (ukb-b-10217) (👉 📊) | Spinal osteochondrosis | Inverse variance weighted | 21 | 2.518088721 | 0.968751032 | 0.009341012 |
| Bread (ukb-b-11348) (👉 📊) | Spinal osteochondrosis | MR Egger | 113 | -7.024491563 | 3.426092288 | 0.042691707 |
| Avocado (ukb-b-12236) (👉 📊) | Spinal osteochondrosis | MR Egger | 24 | 8.779329125 | 4.009029122 | 0.039424734 |
| Cheese (ukb-b-1489) (👉 📊) | Spinal osteochondrosis | Weighted mode | 199 | -5.973898461 | 2.902019821 | 0.040848563 |
| Other vegetarian alternative (ukb-b-16150) (👉 📊) | Spinal osteochondrosis | Simple mode | 29 | -24.06952397 | 8.880285782 | 0.011343571 |
| Ice-cream (ukb-b-17189) (👉 📊) | Spinal osteochondrosis | MR Egger | 16 | 8.787374825 | 3.725526026 | 0.033405045 |
| Fruitcake (ukb-b-17775) (👉 📊) | Spinal osteochondrosis | MR Egger | 13 | 22.63227033 | 7.908401287 | 0.015466731 |
| Powdered/instant soup (ukb-b-19931) (👉 📊) | Spinal osteochondrosis | MR Egger | 18 | -12.68339319 | 5.909012657 | 0.047515779 |
| White pasta (ukb-b-2512) (👉 📊) | Spinal osteochondrosis | Inverse variance weighted | 10 | 5.112368931 | 2.165149203 | 0.018215481 |
| Cake (ukb-b-3433) (👉 📊) | Spinal osteochondrosis | Weighted median | 10 | 5.088354395 | 2.57921233 | 0.048514628 |
| Cake (ukb-b-3433) (👉 📊) | Spinal osteochondrosis | Inverse variance weighted | 10 | 5.805131112 | 2.08379301 | 0.005338786 |
| Other cheese (ukb-b-4088) (👉 📊) | Spinal osteochondrosis | MR Egger | 17 | 23.91306678 | 9.601669841 | 0.024968884 |
| Danish pastry (ukb-b-447) (👉 📊) | Spinal osteochondrosis | MR Egger | 16 | 23.53420185 | 9.703501425 | 0.029405394 |
| Olives (ukb-b-5232) (👉 📊) | Spinal osteochondrosis | MR Egger | 23 | -8.705748445 | 4.145614056 | 0.047989439 |
| Pulses (ukb-b-621) (👉 📊) | Spinal osteochondrosis | Weighted median | 6 | 7.579258159 | 2.949566769 | 0.010181088 |
| Pulses (ukb-b-621) (👉 📊) | Spinal osteochondrosis | Inverse variance weighted | 6 | 5.527029507 | 2.240202888 | 0.013617412 |
| Mango (ukb-b-6218) (👉 📊) | Spinal osteochondrosis | Weighted median | 25 | -7.41295999 | 3.21168676 | 0.020992436 |
| Mango (ukb-b-6218) (👉 📊) | Spinal osteochondrosis | Inverse variance weighted | 25 | -6.864392566 | 2.128515864 | 0.001259874 |
| Mango (ukb-b-6218) (👉 📊) | Spinal osteochondrosis | Weighted mode | 25 | -7.229331951 | 2.851269199 | 0.018157617 |
| Fresh tomato (ukb-b-730) (👉 📊) | Spinal osteochondrosis | Weighted median | 10 | 2.64777935 | 1.211157767 | 0.028804222 |
| Courgette (ukb-b-7420) (👉 📊) | Spinal osteochondrosis | MR Egger | 19 | -9.620953181 | 3.883899213 | 0.024045652 |
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Sweets (ukb-b-10217) | Spinal osteochondrosis | rs142705784 | 11.5775419277015 | 4.91993851900852 | 0.0186132040496017 |
| Sweets (ukb-b-10217) | Spinal osteochondrosis | All - Inverse variance weighted | 2.51808872122078 | 0.968751031994419 | 0.0093410116188025 |
| Bread (ukb-b-11348) | Spinal osteochondrosis | rs11013753 | -23.1594418097244 | 9.67438900589403 | 0.0166706597054028 |
| Bread (ukb-b-11348) | Spinal osteochondrosis | rs4473606 | 26.8486371991023 | 11.9220352357623 | 0.0243211385112847 |
| Bread (ukb-b-11348) | Spinal osteochondrosis | rs4800666 | 23.9017523421193 | 10.5237609824766 | 0.0231338017131115 |
| Bread (ukb-b-11348) | Spinal osteochondrosis | rs61860539 | 33.2870335203412 | 16.7818736232136 | 0.0473103623871196 |
| Bread (ukb-b-11348) | Spinal osteochondrosis | rs6462253 | 22.4068465955963 | 11.208745589151 | 0.0456029082730648 |
| Bread (ukb-b-11348) | Spinal osteochondrosis | rs8047941 | -22.9098299542116 | 11.1160121671323 | 0.0393053670300141 |
| Bread (ukb-b-11348) | Spinal osteochondrosis | rs9607542 | -22.0649695277821 | 11.2313048276758 | 0.0494610876203242 |
| Bread (ukb-b-11348) | Spinal osteochondrosis | All - MR Egger | -7.02449156328092 | 3.42609228779031 | 0.0426917066411406 |
| Avocado (ukb-b-12236) | Spinal osteochondrosis | rs141678669 | 36.9197846985698 | 14.7280553445558 | 0.0121841428971086 |
| Avocado (ukb-b-12236) | Spinal osteochondrosis | All - MR Egger | 8.77932912511555 | 4.00902912220665 | 0.0394247342298054 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs113811945 | 14.6936114012257 | 7.29983477285412 | 0.0441284085310614 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs11735256 | 17.2965189290558 | 8.81569914438324 | 0.0497609363711555 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs1519043 | 23.2915234566799 | 9.67727536490649 | 0.0160918097058898 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs34423638 | -21.9429483343307 | 10.3730301216836 | 0.0343971799432385 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs3733421 | -20.5675917471385 | 9.78574656668788 | 0.0355716086091343 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs519250 | -18.4761184223625 | 8.4682209435828 | 0.029122954152385 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs62098037 | -24.5300237269575 | 9.70067530571272 | 0.0114488323348304 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs6694085 | 23.0895342370776 | 9.64170416218285 | 0.0166314036894453 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs7259537 | 20.8090576286115 | 10.2026772852804 | 0.0413933375470993 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs75499503 | -21.8130652129337 | 8.8737104837056 | 0.0139648090153821 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs77742462 | 18.8742447352676 | 7.95082036286415 | 0.0176025621593114 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs78370515 | -16.3678461806581 | 8.18747977137654 | 0.0455941611939609 |
| Cheese (ukb-b-1489) | Spinal osteochondrosis | rs7936836 | 14.2741261027863 | 6.70317992315867 | 0.0332165589680229 |
| Ice-cream (ukb-b-17189) | Spinal osteochondrosis | rs496092 | 19.9961752683288 | 8.96819894979243 | 0.0257689802612642 |
| Ice-cream (ukb-b-17189) | Spinal osteochondrosis | All - MR Egger | 8.7873748253535 | 3.72552602569294 | 0.0334050451534286 |
| Fruitcake (ukb-b-17775) | Spinal osteochondrosis | rs139464753 | 23.675536709507 | 10.7420970471093 | 0.0275246398906057 |
| Fruitcake (ukb-b-17775) | Spinal osteochondrosis | All - MR Egger | 22.6322703329981 | 7.90840128701854 | 0.0154667308357903 |
| Powdered/instant soup (ukb-b-19931) | Spinal osteochondrosis | All - MR Egger | -12.6833931888654 | 5.90901265711709 | 0.047515778517876 |
| White pasta (ukb-b-2512) | Spinal osteochondrosis | rs10804975 | 14.7364940980555 | 7.13865896067003 | 0.038987151928147 |
| White pasta (ukb-b-2512) | Spinal osteochondrosis | rs2993494 | 11.3087952098423 | 5.20025260597366 | 0.0296554043513086 |
| White pasta (ukb-b-2512) | Spinal osteochondrosis | All - Inverse variance weighted | 5.11236893073732 | 2.16514920258863 | 0.0182154808999834 |
| Cake (ukb-b-3433) | Spinal osteochondrosis | rs1468944 | 11.8720044826448 | 5.68835613011677 | 0.036881695337264 |
| Cake (ukb-b-3433) | Spinal osteochondrosis | rs35268725 | 18.3095480051253 | 6.4949410153316 | 0.0048166371937554 |
| Cake (ukb-b-3433) | Spinal osteochondrosis | All - Inverse variance weighted | 5.80513111248677 | 2.08379300958328 | 0.0053387858092583 |
| Other cheese (ukb-b-4088) | Spinal osteochondrosis | All - MR Egger | 23.9130667766096 | 9.6016698405883 | 0.0249688841835847 |
| Danish pastry (ukb-b-447) | Spinal osteochondrosis | rs114646421 | 32.73610456255 | 16.5215627364335 | 0.0475445336813363 |
| Danish pastry (ukb-b-447) | Spinal osteochondrosis | rs150700637 | 46.0315036365253 | 20.6293889589122 | 0.0256575800415287 |
| Danish pastry (ukb-b-447) | Spinal osteochondrosis | All - MR Egger | 23.5342018497172 | 9.70350142549726 | 0.0294053938514069 |
| Olives (ukb-b-5232) | Spinal osteochondrosis | All - MR Egger | -8.70574844474426 | 4.14561405633877 | 0.0479894391483991 |
| Pulses (ukb-b-621) | Spinal osteochondrosis | rs139435676 | 10.0427053041013 | 5.11657888761107 | 0.0496720472553645 |
| Pulses (ukb-b-621) | Spinal osteochondrosis | All - Inverse variance weighted | 5.52702950671016 | 2.24020288844879 | 0.0136174115317401 |
| Mango (ukb-b-6218) | Spinal osteochondrosis | rs71559841 | -7.48610751202096 | 2.80618290465401 | 0.0076368095251536 |
| Mango (ukb-b-6218) | Spinal osteochondrosis | All - Inverse variance weighted | -6.86439256623698 | 2.12851586380286 | 0.0012598736671377 |
| Courgette (ukb-b-7420) | Spinal osteochondrosis | rs17577288 | 19.4194325333441 | 6.56552168939993 | 0.0030985342137975 |
| Courgette (ukb-b-7420) | Spinal osteochondrosis | rs77575696 | -13.0640943837656 | 6.03535637878617 | 0.0304188140356483 |
| Courgette (ukb-b-7420) | Spinal osteochondrosis | All - MR Egger | -9.62095318116413 | 3.88389921265804 | 0.0240456516614058 |