ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Spontaneous rupture of synovium and tendon (finn-b-M13_SPONTRUPTSYNOTEND)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sweetened cereal (ukb-b-10640) (👉 📊) Spontaneous rupture of synovium and tendon MR Egger 16 -6.865357036 2.605685903 0.019603601
Satsuma (ukb-b-11563) (👉 📊) Spontaneous rupture of synovium and tendon MR Egger 18 -2.477571403 0.989916164 0.023540778
Chocolate-covered raisin (ukb-b-1160) (👉 📊) Spontaneous rupture of synovium and tendon MR Egger 51 -4.471066852 1.74524529 0.013538178
Other sweets (ukb-b-139) (👉 📊) Spontaneous rupture of synovium and tendon MR Egger 26 -2.736173746 0.986832059 0.0105784
Water (ukb-b-14898) (👉 📊) Spontaneous rupture of synovium and tendon Inverse variance weighted 153 -0.695013631 0.349006461 0.046436248
Water (ukb-b-14898) (👉 📊) Spontaneous rupture of synovium and tendon Simple mode 153 -2.874882774 1.445982768 0.048586838
Hot chocolate (ukb-b-16449) (👉 📊) Spontaneous rupture of synovium and tendon Inverse variance weighted 18 2.075610961 0.968290323 0.03206629
Plain cereal (ukb-b-20023) (👉 📊) Spontaneous rupture of synovium and tendon Inverse variance weighted 13 1.723438005 0.669953952 0.010097503
Prune (ukb-b-3022) (👉 📊) Spontaneous rupture of synovium and tendon Inverse variance weighted 15 2.13828171 0.965515115 0.026783837
Wholemeal pasta (ukb-b-4150) (👉 📊) Spontaneous rupture of synovium and tendon Inverse variance weighted 22 2.450659887 1.103395908 0.026349883
Instant coffee (ukb-b-930) (👉 📊) Spontaneous rupture of synovium and tendon Inverse variance weighted 21 0.388430284 0.16050175 0.01551624

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sweetened cereal (ukb-b-10640) Spontaneous rupture of synovium and tendon rs112071479 -8.78303569597933 4.01092817747524 0.0285404601600654
Sweetened cereal (ukb-b-10640) Spontaneous rupture of synovium and tendon All - MR Egger -6.86535703601406 2.60568590312643 0.0196036008908658
Satsuma (ukb-b-11563) Spontaneous rupture of synovium and tendon rs117352891 -3.63072299377106 1.23447813406368 0.0032704948630778
Satsuma (ukb-b-11563) Spontaneous rupture of synovium and tendon rs4344518 -3.8500994884435 1.85069159959516 0.0374927871231613
Satsuma (ukb-b-11563) Spontaneous rupture of synovium and tendon All - MR Egger -2.4775714032773 0.989916164013056 0.0235407781058289
Chocolate-covered raisin (ukb-b-1160) Spontaneous rupture of synovium and tendon rs374956 26.1219990200882 8.33170014698677 0.0017170517391642
Chocolate-covered raisin (ukb-b-1160) Spontaneous rupture of synovium and tendon All - MR Egger -4.47106685219859 1.74524528978231 0.0135381784217435
Other sweets (ukb-b-139) Spontaneous rupture of synovium and tendon rs116350919 -6.13365624806977 3.08119265857369 0.0465165199211369
Other sweets (ukb-b-139) Spontaneous rupture of synovium and tendon rs76694902 -4.94921626292332 1.95615923354455 0.0114040358831213
Other sweets (ukb-b-139) Spontaneous rupture of synovium and tendon All - MR Egger -2.73617374558597 0.986832059301059 0.0105783999672044
Water (ukb-b-14898) Spontaneous rupture of synovium and tendon rs13274119 -9.24477314748969 4.58287899619147 0.0436703297811753
Water (ukb-b-14898) Spontaneous rupture of synovium and tendon rs13409451 10.709769689906 5.02680778799327 0.0331278014795009
Water (ukb-b-14898) Spontaneous rupture of synovium and tendon rs17444495 -9.99284029464603 4.75483499734256 0.0355868720695693
Water (ukb-b-14898) Spontaneous rupture of synovium and tendon rs2675638 -11.1089425285269 5.00413039334054 0.026421846296763
Water (ukb-b-14898) Spontaneous rupture of synovium and tendon All - Inverse variance weighted -0.695013630742771 0.349006461396176 0.0464362482822865
Hot chocolate (ukb-b-16449) Spontaneous rupture of synovium and tendon All - Inverse variance weighted 2.07561096146103 0.96829032282037 0.032066290396517
Plain cereal (ukb-b-20023) Spontaneous rupture of synovium and tendon All - Inverse variance weighted 1.72343800497502 0.669953951521582 0.01009750261135
Prune (ukb-b-3022) Spontaneous rupture of synovium and tendon All - Inverse variance weighted 2.13828170960819 0.965515115243996 0.0267838368950025
Wholemeal pasta (ukb-b-4150) Spontaneous rupture of synovium and tendon rs141836859 19.3008423262198 7.6482144298824 0.0116168294939303
Wholemeal pasta (ukb-b-4150) Spontaneous rupture of synovium and tendon rs3821340 12.6899182705681 5.76212364060244 0.0276442053401498
Wholemeal pasta (ukb-b-4150) Spontaneous rupture of synovium and tendon All - Inverse variance weighted 2.450659887487 1.10339590845406 0.0263498825973988
Instant coffee (ukb-b-930) Spontaneous rupture of synovium and tendon rs112601576 1.74664247304707 0.759913644671664 0.0215347722683216
Instant coffee (ukb-b-930) Spontaneous rupture of synovium and tendon All - Inverse variance weighted 0.388430284158523 0.160501750407328 0.0155162400068582