Osteonecrosis due to drugs (finn-b-OSTEON_DRUGS)

Mendelian Randomization Results

Intake (exposure)	Outcome	Method	Number of SNPs	b	se	P-value
Homemade soup (ukb-b-12658) (👉 📊)	Osteonecrosis due to drugs	Weighted median	16	-7.052680218	3.519147589	0.045060672
Other drink (ukb-b-1310) (👉 📊)	Osteonecrosis due to drugs	MR Egger	18	-13.62208578	5.147890039	0.01760693
Sweetcorn (ukb-b-13567) (👉 📊)	Osteonecrosis due to drugs	Inverse variance weighted	20	4.69288232	2.070967526	0.023449317
Grapefruit juice (ukb-b-14351) (👉 📊)	Osteonecrosis due to drugs	Inverse variance weighted	20	8.475319789	4.1051919	0.038966848
Unsalted peanuts (ukb-b-15555) (👉 📊)	Osteonecrosis due to drugs	Inverse variance weighted	45	-8.037123134	3.749312224	0.032062866
Hot chocolate (ukb-b-16449) (👉 📊)	Osteonecrosis due to drugs	Simple mode	18	-19.43176818	8.821175735	0.041689825
Other fruit (ukb-b-18659) (👉 📊)	Osteonecrosis due to drugs	Inverse variance weighted	20	-5.72296776	2.502541851	0.022203882
Pizza (ukb-b-3852) (👉 📊)	Osteonecrosis due to drugs	Inverse variance weighted	16	-5.634453846	2.019443813	0.005269147
Mushroom (ukb-b-4043) (👉 📊)	Osteonecrosis due to drugs	MR Egger	9	-14.16319626	5.82087328	0.04520949
Doughnut (ukb-b-6214) (👉 📊)	Osteonecrosis due to drugs	Simple mode	31	-23.11420822	10.30360572	0.032414456

Mendelian Randomization Results (Single SNP)

Intake (exposure)	Outcome	SNP	b	se	P-value
Homemade soup (ukb-b-12658)	Osteonecrosis due to drugs	rs2319386	19.9039982789607	8.86066304830115	0.0246826973770627
Other drink (ukb-b-1310)	Osteonecrosis due to drugs	rs75805105	-13.6823420389731	6.90969367111738	0.0476848535680486
Other drink (ukb-b-1310)	Osteonecrosis due to drugs	All - MR Egger	-13.6220857793685	5.14789003949537	0.0176069304139596
Sweetcorn (ukb-b-13567)	Osteonecrosis due to drugs	rs76166697	22.3363822130356	7.60985561304701	0.0033334207781984
Sweetcorn (ukb-b-13567)	Osteonecrosis due to drugs	All - Inverse variance weighted	4.69288231995321	2.07096752640879	0.0234493166251408
Grapefruit juice (ukb-b-14351)	Osteonecrosis due to drugs	rs12141930	38.1946841199221	19.1496348914505	0.0460932365226372
Grapefruit juice (ukb-b-14351)	Osteonecrosis due to drugs	rs141538567	40.3480869018959	19.2181298590005	0.0357745741056932
Grapefruit juice (ukb-b-14351)	Osteonecrosis due to drugs	rs1610378	34.2087043939265	16.6538632979581	0.0399659920269987
Grapefruit juice (ukb-b-14351)	Osteonecrosis due to drugs	rs76621665	44.621300187785	14.6651166949835	0.0023447925437146
Grapefruit juice (ukb-b-14351)	Osteonecrosis due to drugs	All - Inverse variance weighted	8.4753197894141	4.10519190043332	0.0389668475587639
Unsalted peanuts (ukb-b-15555)	Osteonecrosis due to drugs	All - Inverse variance weighted	-8.03712313363182	3.74931222439708	0.0320628664914443
Hot chocolate (ukb-b-16449)	Osteonecrosis due to drugs	rs1789571	-25.1456018208596	12.0247021020217	0.0365135315970614
Other fruit (ukb-b-18659)	Osteonecrosis due to drugs	rs926923	-25.7998152657654	12.3925882385871	0.0373539211013497
Other fruit (ukb-b-18659)	Osteonecrosis due to drugs	All - Inverse variance weighted	-5.72296776043608	2.502541850714	0.022203881608499
Pizza (ukb-b-3852)	Osteonecrosis due to drugs	All - Inverse variance weighted	-5.63445384594646	2.0194438134886	0.0052691469089202
Mushroom (ukb-b-4043)	Osteonecrosis due to drugs	rs56270010	-11.3413065731109	5.02716559199993	0.0240703695516857
Mushroom (ukb-b-4043)	Osteonecrosis due to drugs	rs80060075	-25.5531223492297	10.364891830341	0.0136878136234974
Mushroom (ukb-b-4043)	Osteonecrosis due to drugs	All - MR Egger	-14.1631962582244	5.82087327958702	0.0452094898706782
Doughnut (ukb-b-6214)	Osteonecrosis due to drugs	rs34987892	118.177076640487	45.3311966619549	0.0091347322730858
Doughnut (ukb-b-6214)	Osteonecrosis due to drugs	rs4467081	50.0200628980428	25.0529008892837	0.045871078796312