ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Postmenopausal osteoporosis with pathological fracture (finn-b-OSTPOPATFRCTURE_POSTEMENO)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Omelette (ukb-b-11272) (👉 📊) Postmenopausal osteoporosis with pathological fracture Weighted median 15 -2.755311782 1.348569589 0.041038925
Beetroot (ukb-b-11880) (👉 📊) Postmenopausal osteoporosis with pathological fracture Inverse variance weighted 10 2.342449911 0.968254898 0.01555258
Crisp (ukb-b-12602) (👉 📊) Postmenopausal osteoporosis with pathological fracture Weighted median 9 2.742881967 1.375839087 0.046195057
Dried fruit (ukb-b-16576) (👉 📊) Postmenopausal osteoporosis with pathological fracture Weighted median 155 1.684144735 0.753599462 0.025430425
Carrot (ukb-b-16710) (👉 📊) Postmenopausal osteoporosis with pathological fracture Weighted median 5 -2.12908438 0.972085273 0.028508004
Carrot (ukb-b-16710) (👉 📊) Postmenopausal osteoporosis with pathological fracture Inverse variance weighted 5 -2.067312607 0.789962468 0.008871265
Other bread (ukb-b-4964) (👉 📊) Postmenopausal osteoporosis with pathological fracture Inverse variance weighted 17 -2.001126426 0.788261116 0.011127813
Lamb (ukb-b-530) (👉 📊) Postmenopausal osteoporosis with pathological fracture MR Egger 13 4.129392252 1.69367514 0.032931985
Watercress (ukb-b-6181) (👉 📊) Postmenopausal osteoporosis with pathological fracture MR Egger 12 8.509757837 2.256089771 0.003650108
Watercress (ukb-b-6181) (👉 📊) Postmenopausal osteoporosis with pathological fracture Inverse variance weighted 12 3.306149665 1.620750778 0.041361507
Spinach (ukb-b-812) (👉 📊) Postmenopausal osteoporosis with pathological fracture Inverse variance weighted 14 2.112404321 1.044563092 0.043146913

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Omelette (ukb-b-11272) Postmenopausal osteoporosis with pathological fracture rs146053608 10.707485032805 3.77489083596209 0.00456107068166
Beetroot (ukb-b-11880) Postmenopausal osteoporosis with pathological fracture All - Inverse variance weighted 2.34244991095855 0.96825489752307 0.0155525803531905
Crisp (ukb-b-12602) Postmenopausal osteoporosis with pathological fracture rs543197 -5.99771605462593 2.90212067159319 0.0387655741776372
Crisp (ukb-b-12602) Postmenopausal osteoporosis with pathological fracture rs57871178 5.61078517594933 2.81281426148782 0.0460731043361826
Dried fruit (ukb-b-16576) Postmenopausal osteoporosis with pathological fracture rs142119647 19.7821020973171 10.0304738383094 0.048586761556268
Dried fruit (ukb-b-16576) Postmenopausal osteoporosis with pathological fracture rs2579020 21.5199379260563 6.90635030589723 0.0018334474364358
Dried fruit (ukb-b-16576) Postmenopausal osteoporosis with pathological fracture rs34419562 -16.567358350883 8.41664929669587 0.0490216784565508
Carrot (ukb-b-16710) Postmenopausal osteoporosis with pathological fracture rs16898247 -4.80157768511477 2.28045692702371 0.0352449237668473
Carrot (ukb-b-16710) Postmenopausal osteoporosis with pathological fracture All - Inverse variance weighted -2.06731260700796 0.789962467907096 0.0088712648404924
Other bread (ukb-b-4964) Postmenopausal osteoporosis with pathological fracture rs149685100 -8.02506458528005 3.9185111682631 0.0405611568538045
Other bread (ukb-b-4964) Postmenopausal osteoporosis with pathological fracture All - Inverse variance weighted -2.00112642584528 0.788261116426606 0.0111278125314505
Lamb (ukb-b-530) Postmenopausal osteoporosis with pathological fracture All - MR Egger 4.12939225163878 1.69367513990739 0.0329319851842541
Watercress (ukb-b-6181) Postmenopausal osteoporosis with pathological fracture rs191852210 8.83127742871094 2.42673738315844 0.000273532401495
Watercress (ukb-b-6181) Postmenopausal osteoporosis with pathological fracture rs7704452 -11.1548334225088 5.2082980582327 0.0322142068876543
Watercress (ukb-b-6181) Postmenopausal osteoporosis with pathological fracture All - Inverse variance weighted 3.30614966538691 1.62075077782399 0.0413615066463395
Watercress (ukb-b-6181) Postmenopausal osteoporosis with pathological fracture All - MR Egger 8.50975783704026 2.25608977077915 0.0036501084993272
Spinach (ukb-b-812) Postmenopausal osteoporosis with pathological fracture rs111686396 8.89903567655979 3.18669710702968 0.005229313359994
Spinach (ukb-b-812) Postmenopausal osteoporosis with pathological fracture All - Inverse variance weighted 2.11240432137677 1.04456309219806 0.0431469125623161