ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Other (seronegative) rheumatoid arthritis, wide (finn-b-RHEUMA_OTHER_WIDE)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sweetened cereal (ukb-b-10640) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Weighted median 16 -2.608934012 1.096055593 0.017298853
Sweetened cereal (ukb-b-10640) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Inverse variance weighted 16 -2.16063193 0.856476185 0.011645791
Sweetened cereal (ukb-b-10640) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Weighted mode 16 -3.132461211 1.416344018 0.042929416
Sweet pepper (ukb-b-10932) (👉 📊) Other (seronegative) rheumatoid arthritis, wide MR Egger 9 2.929092357 1.187074687 0.042990942
Celery (ukb-b-14145) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Inverse variance weighted 15 -0.90431957 0.331853764 0.006429089
Grapefruit juice (ukb-b-14351) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Inverse variance weighted 20 2.216042539 0.784687677 0.004741244
Cereal (ukb-b-15926) (👉 📊) Other (seronegative) rheumatoid arthritis, wide MR Egger 175 1.686210344 0.686111892 0.014971455
Other bread (ukb-b-4964) (👉 📊) Other (seronegative) rheumatoid arthritis, wide MR Egger 17 -1.577533089 0.624238921 0.023226534
Lamb (ukb-b-530) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Weighted median 13 1.516905564 0.685617821 0.026934539
Lamb (ukb-b-530) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Inverse variance weighted 13 1.358730803 0.506832295 0.007343999
Lamb (ukb-b-530) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Weighted mode 13 1.538740764 0.665287158 0.039269529
Poultry (ukb-b-8006) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Inverse variance weighted 80 0.66958835 0.327907335 0.041151056
Soft cheese (ukb-b-8007) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Inverse variance weighted 16 -2.450395811 0.700573201 0.000469286
Squash (ukb-b-8793) (👉 📊) Other (seronegative) rheumatoid arthritis, wide Inverse variance weighted 18 0.661832388 0.28776862 0.021455198

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sweetened cereal (ukb-b-10640) Other (seronegative) rheumatoid arthritis, wide rs184935820 -3.56270843904364 1.68485968176318 0.0344689064011745
Sweetened cereal (ukb-b-10640) Other (seronegative) rheumatoid arthritis, wide rs61873036 -5.27960278521973 2.39088711737618 0.027228998138118
Sweetened cereal (ukb-b-10640) Other (seronegative) rheumatoid arthritis, wide rs7258015 -7.94614923783532 3.45303867403315 0.0213800566244946
Sweetened cereal (ukb-b-10640) Other (seronegative) rheumatoid arthritis, wide All - Inverse variance weighted -2.16063193044736 0.856476185056419 0.0116457914843929
Sweet pepper (ukb-b-10932) Other (seronegative) rheumatoid arthritis, wide rs28608590 -3.72675419665938 1.29020880033787 0.0038709731110456
Sweet pepper (ukb-b-10932) Other (seronegative) rheumatoid arthritis, wide rs78836938 3.98519719641827 1.88127395869294 0.0341454142761238
Sweet pepper (ukb-b-10932) Other (seronegative) rheumatoid arthritis, wide All - MR Egger 2.92909235718177 1.18707468734402 0.0429909424772631
Celery (ukb-b-14145) Other (seronegative) rheumatoid arthritis, wide rs116191942 -2.46458953191133 0.992645518166199 0.0130336102648296
Celery (ukb-b-14145) Other (seronegative) rheumatoid arthritis, wide rs3110454 -3.09911658633962 1.49441386992533 0.0380978206130131
Celery (ukb-b-14145) Other (seronegative) rheumatoid arthritis, wide All - Inverse variance weighted -0.904319570412152 0.331853764322317 0.0064290887498956
Grapefruit juice (ukb-b-14351) Other (seronegative) rheumatoid arthritis, wide rs11074030 10.2881349480891 3.30250251326039 0.0018378642828056
Grapefruit juice (ukb-b-14351) Other (seronegative) rheumatoid arthritis, wide rs145311903 7.11040027772095 3.5644988314643 0.0460665949641679
Grapefruit juice (ukb-b-14351) Other (seronegative) rheumatoid arthritis, wide rs79766916 -11.5759873700599 4.50007215859146 0.0100996014671243
Grapefruit juice (ukb-b-14351) Other (seronegative) rheumatoid arthritis, wide All - Inverse variance weighted 2.21604253932599 0.784687676856885 0.0047412444640935
Cereal (ukb-b-15926) Other (seronegative) rheumatoid arthritis, wide rs1500962 -5.18002717391304 2.54755434782609 0.0420188576796856
Cereal (ukb-b-15926) Other (seronegative) rheumatoid arthritis, wide rs2339515 -6.55544078783857 3.0668062120497 0.0325535704242349
Cereal (ukb-b-15926) Other (seronegative) rheumatoid arthritis, wide rs4730682 5.77920024017456 2.89496115927111 0.0459016809600058
Cereal (ukb-b-15926) Other (seronegative) rheumatoid arthritis, wide rs62377431 -5.96856829873046 2.88601482728908 0.0386305870155779
Cereal (ukb-b-15926) Other (seronegative) rheumatoid arthritis, wide rs6918737 -5.199344620426 2.24285454214455 0.0204394417439632
Cereal (ukb-b-15926) Other (seronegative) rheumatoid arthritis, wide rs79725647 13.8413906145658 3.79761350682289 0.0002676412217759
Cereal (ukb-b-15926) Other (seronegative) rheumatoid arthritis, wide All - MR Egger 1.68621034418029 0.686111892269592 0.0149714548944755
Other bread (ukb-b-4964) Other (seronegative) rheumatoid arthritis, wide rs74006323 -5.11579304616539 2.18635848062376 0.0192904903545645
Other bread (ukb-b-4964) Other (seronegative) rheumatoid arthritis, wide rs7780072 3.72867138589959 1.55489177134907 0.0164836809514035
Other bread (ukb-b-4964) Other (seronegative) rheumatoid arthritis, wide All - MR Egger -1.57753308903032 0.624238920756276 0.0232265343315427
Lamb (ukb-b-530) Other (seronegative) rheumatoid arthritis, wide rs142252464 1.49246938920778 0.716478659088018 0.0372455826449668
Lamb (ukb-b-530) Other (seronegative) rheumatoid arthritis, wide rs147244930 5.78850017964311 2.78446818986281 0.037630859468905
Lamb (ukb-b-530) Other (seronegative) rheumatoid arthritis, wide All - Inverse variance weighted 1.35873080299604 0.506832294866679 0.0073439994946597
Poultry (ukb-b-8006) Other (seronegative) rheumatoid arthritis, wide rs1000294 10.840685528851 3.32623466179901 0.0011174800911283
Poultry (ukb-b-8006) Other (seronegative) rheumatoid arthritis, wide rs11976316 5.67257098614249 2.67037464250162 0.0336483788525471
Poultry (ukb-b-8006) Other (seronegative) rheumatoid arthritis, wide rs34552305 6.51397499248656 2.98440699763065 0.0290601362572084
Poultry (ukb-b-8006) Other (seronegative) rheumatoid arthritis, wide rs7045589 8.46753102620516 2.74372667960774 0.0020277174036977
Poultry (ukb-b-8006) Other (seronegative) rheumatoid arthritis, wide rs7625597 -7.22403022789092 2.78479685883135 0.0094840017650046
Poultry (ukb-b-8006) Other (seronegative) rheumatoid arthritis, wide All - Inverse variance weighted 0.669588349998822 0.327907335163288 0.0411510559131081
Soft cheese (ukb-b-8007) Other (seronegative) rheumatoid arthritis, wide rs2284636 -9.01534681451989 3.14328183954525 0.0041290339818925
Soft cheese (ukb-b-8007) Other (seronegative) rheumatoid arthritis, wide rs6029122 -6.38054535604647 3.22466914894532 0.0478535482890884
Soft cheese (ukb-b-8007) Other (seronegative) rheumatoid arthritis, wide All - Inverse variance weighted -2.45039581105259 0.700573200794312 0.0004692863688638
Squash (ukb-b-8793) Other (seronegative) rheumatoid arthritis, wide All - Inverse variance weighted 0.661832387901289 0.287768619765769 0.0214551977553245