ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Cereal (ukb-b-15926) (👉 📊) Seronegative rheumatoid arthritis MR Egger 175 2.007902281 0.921705399 0.030724321
Garlic (ukb-b-17223) (👉 📊) Seronegative rheumatoid arthritis Inverse variance weighted 19 0.947196992 0.419415082 0.023922222
Espresso (ukb-b-19142) (👉 📊) Seronegative rheumatoid arthritis Weighted median 33 -1.480717006 0.686861221 0.03110138
Cheesy biscuits (ukb-b-19847) (👉 📊) Seronegative rheumatoid arthritis MR Egger 24 -3.65717445 1.583529578 0.030685061
Oily fish (ukb-b-2209) (👉 📊) Seronegative rheumatoid arthritis Weighted median 168 -0.71796622 0.353001452 0.04196266
Turnip/swede (ukb-b-5008) (👉 📊) Seronegative rheumatoid arthritis Inverse variance weighted 19 1.717660028 0.860888445 0.04601912
Coffee (ukb-b-5237) (👉 📊) Seronegative rheumatoid arthritis MR Egger 117 1.398842723 0.659493784 0.036062547
Poultry (ukb-b-8006) (👉 📊) Seronegative rheumatoid arthritis Weighted median 80 1.403307415 0.569660134 0.01376218
Poultry (ukb-b-8006) (👉 📊) Seronegative rheumatoid arthritis Inverse variance weighted 80 0.806916392 0.402999293 0.045254901
Soft cheese (ukb-b-8007) (👉 📊) Seronegative rheumatoid arthritis Inverse variance weighted 16 -2.275985384 0.925538936 0.013928892
Soft cheese (ukb-b-8007) (👉 📊) Seronegative rheumatoid arthritis Simple mode 16 -7.190388496 2.541448801 0.012687845
Squash (ukb-b-8793) (👉 📊) Seronegative rheumatoid arthritis MR Egger 18 2.022980618 0.889534526 0.037076097

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs10737693 -8.13733242612038 4.1192372055389 0.0482175083672907
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs117477397 9.54362195344206 3.77388683673605 0.0114434484799929
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs17811999 -8.75087922545409 3.88927965575738 0.0244489453100894
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs2873054 -8.38195208127068 3.80271123033125 0.0275099862472336
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs614397 -9.01541912909545 3.88408029331503 0.0202803310437025
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs62081186 8.14451928965095 3.6042341002537 0.023839333641428
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs62377431 -7.48915675611933 3.5790721514051 0.0363951031187277
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs6545770 9.36043123543124 3.54749417249417 0.0083248236013679
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs6918737 -7.8062989259057 2.78900418714728 0.0051268184361806
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs76187305 7.42905492579946 3.63651638532672 0.0410619135309675
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs79725647 12.458600616522 4.68125004215823 0.0077820315377118
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs9319377 8.18090470135252 3.67251482788977 0.0259070067452102
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis rs9987289 5.68057801980087 2.77033115251373 0.0403151714510785
Cereal (ukb-b-15926) Seronegative rheumatoid arthritis All - MR Egger 2.00790228056912 0.92170539946201 0.0307243210079033
Garlic (ukb-b-17223) Seronegative rheumatoid arthritis All - Inverse variance weighted 0.947196992281224 0.419415082306268 0.0239222222992607
Espresso (ukb-b-19142) Seronegative rheumatoid arthritis rs73269888 7.43302447056632 3.23184179002129 0.0214519304783441
Cheesy biscuits (ukb-b-19847) Seronegative rheumatoid arthritis rs62139637 11.1030492611558 5.02878219832011 0.0272512303558248
Cheesy biscuits (ukb-b-19847) Seronegative rheumatoid arthritis All - MR Egger -3.65717444991698 1.58352957830122 0.0306850609651979
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs1053924 -9.81889417502899 3.0943909167233 0.0015080674126307
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs11265908 8.21180521202287 3.33419079090567 0.0137815268816238
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs12855717 -5.53565880063451 2.74738752882304 0.043917124237734
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs13138393 12.983899580948 3.56721613302264 0.0002728658352764
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs4974084 -11.1673448491022 3.81844265136445 0.0034492029379062
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs59733471 6.29162103176189 3.0858522468362 0.0414639916938589
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs61882686 -6.6663629599259 3.14842654599385 0.0342290226797196
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs6842641 6.64929028509639 3.2842975073231 0.0429115348352104
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs72484727 7.58410387566398 3.35431831595514 0.0237594386574652
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs730925 -7.142103900835 3.2115500762144 0.0261564788469179
Oily fish (ukb-b-2209) Seronegative rheumatoid arthritis rs7561608 -6.96308221403252 3.52809960621856 0.0484264428375245
Turnip/swede (ukb-b-5008) Seronegative rheumatoid arthritis rs1276460 7.76109994878462 3.37824528227554 0.0215973243496854
Turnip/swede (ukb-b-5008) Seronegative rheumatoid arthritis rs142228490 5.25446101822761 2.23730092016991 0.0188455841819889
Turnip/swede (ukb-b-5008) Seronegative rheumatoid arthritis rs79218601 11.6326117742262 4.99527951985973 0.0198738566534446
Turnip/swede (ukb-b-5008) Seronegative rheumatoid arthritis All - Inverse variance weighted 1.71766002781719 0.86088844457682 0.0460191204392833
Coffee (ukb-b-5237) Seronegative rheumatoid arthritis rs12649199 -10.2636102337783 4.27354474555244 0.016320778505082
Coffee (ukb-b-5237) Seronegative rheumatoid arthritis rs6937318 -11.7555412255887 4.00088490160177 0.0033008640126782
Coffee (ukb-b-5237) Seronegative rheumatoid arthritis All - MR Egger 1.39884272289515 0.659493784213065 0.0360625465130681
Poultry (ukb-b-8006) Seronegative rheumatoid arthritis rs1000294 11.6418213162965 4.11722948990974 0.0046900385819519
Poultry (ukb-b-8006) Seronegative rheumatoid arthritis rs7045589 12.1258332656821 3.4013989923227 0.0003639190616816
Poultry (ukb-b-8006) Seronegative rheumatoid arthritis rs7625597 -7.14182220253797 3.45273706482411 0.0385975039918924
Poultry (ukb-b-8006) Seronegative rheumatoid arthritis All - Inverse variance weighted 0.80691639194803 0.402999292822788 0.045254901067289
Soft cheese (ukb-b-8007) Seronegative rheumatoid arthritis rs6029122 -8.0831706666896 3.98999062696167 0.0427789212015214
Soft cheese (ukb-b-8007) Seronegative rheumatoid arthritis rs79474565 -10.5452530298528 4.88310269775361 0.0308083383558928
Soft cheese (ukb-b-8007) Seronegative rheumatoid arthritis All - Inverse variance weighted -2.27598538351091 0.925538936208413 0.0139288922861554
Squash (ukb-b-8793) Seronegative rheumatoid arthritis All - MR Egger 2.022980617953 0.889534526372623 0.0370760974295242