ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Plum (ukb-b-14182) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 11 -0.623274583 0.312387638 0.046021501
Grapefruit juice (ukb-b-14351) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 20 1.360308809 0.55938473 0.015024221
Cheese (ukb-b-1489) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 198 -0.39086348 0.156651771 0.012591791
Cheesecake (ukb-b-1814) (👉 📊) Seropositive rheumatoid arthritis MR Egger 26 3.040962185 1.307027742 0.028751293
Cheesecake (ukb-b-1814) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 26 1.899166091 0.711049585 0.007564065
Espresso (ukb-b-19142) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 33 -0.622533208 0.294797638 0.034709559
Coleslaw (ukb-b-2691) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 19 -0.702756248 0.358406545 0.049904737
Prune (ukb-b-3022) (👉 📊) Seropositive rheumatoid arthritis MR Egger 15 2.302234703 0.912855368 0.025506783
Prune (ukb-b-3022) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 15 1.270652714 0.506150471 0.012058599
Pork (ukb-b-5185) (👉 📊) Seropositive rheumatoid arthritis MR Egger 16 -2.256449915 0.908164311 0.026233855
Pork (ukb-b-5640) (👉 📊) Seropositive rheumatoid arthritis Weighted median 82 -0.994509759 0.465412338 0.032611347
Pork (ukb-b-5640) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 82 -0.825891676 0.336520302 0.014119428
Bread roll (ukb-b-6246) (👉 📊) Seropositive rheumatoid arthritis Weighted median 18 0.649109248 0.326996076 0.047136974
Bread roll (ukb-b-6246) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 18 0.861893811 0.27448627 0.001689333
Liver (ukb-b-6373) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 28 -1.408003247 0.593728469 0.01771797
Fortified wine (ukb-b-9524) (👉 📊) Seropositive rheumatoid arthritis Inverse variance weighted 20 -1.78956178 0.595183894 0.002640676

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Plum (ukb-b-14182) Seropositive rheumatoid arthritis All - Inverse variance weighted -0.62327458349342 0.312387637931589 0.0460215009181249
Grapefruit juice (ukb-b-14351) Seropositive rheumatoid arthritis All - Inverse variance weighted 1.36030880898409 0.559384729748534 0.0150242214162487
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs1032001 -6.48383422413038 2.21438073010841 0.0034108690071087
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs12666766 4.71414332791581 2.13707830865517 0.0273922381359285
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs1473781 -5.49856171880966 1.95164999278738 0.0048415499339437
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs1647396 -5.49165120593692 1.88002473716759 0.0034885088878421
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs17115145 -4.39420523888639 1.77786749064485 0.0134504011601665
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs2245959 -7.96086125973498 2.16092868070982 0.0002296022398279
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs281219 -5.54931526210472 2.00102654893589 0.0055502160565244
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs34423638 -5.53560742070616 2.22991650280699 0.0130490393596293
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs61953351 3.63182852287367 1.70627415508593 0.0332944857913185
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs62034322 -4.69305012378458 1.60740554698432 0.0035043273665157
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs62048491 -4.85576962711976 2.06926685298312 0.0189448928706258
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs6544743 -3.87333514541995 1.96309383588536 0.0484867990236486
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs67238148 4.14067411383529 1.66835920499057 0.0130689790731142
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs6857 5.43578525683262 1.89099438631632 0.0040458517460701
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs7607369 -3.81348734499745 1.92797689825038 0.0479316885493628
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis rs78548855 5.67461616594055 1.74883387757044 0.0011753314097609
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis All - Inverse variance weighted -0.390863480296425 0.156651771036581 0.0125917907777137
Cheesecake (ukb-b-1814) Seropositive rheumatoid arthritis rs28694319 8.0195697677351 3.36250304726839 0.017079121353364
Cheesecake (ukb-b-1814) Seropositive rheumatoid arthritis rs73084384 8.82652124157613 3.94526779785536 0.0252704875731762
Cheesecake (ukb-b-1814) Seropositive rheumatoid arthritis rs79910083 10.3643892164767 2.7034784333754 0.0001262179343639
Cheesecake (ukb-b-1814) Seropositive rheumatoid arthritis All - Inverse variance weighted 1.89916609080286 0.711049584934406 0.0075640651367247
Cheesecake (ukb-b-1814) Seropositive rheumatoid arthritis All - MR Egger 3.04096218468789 1.3070277421112 0.028751293031908
Espresso (ukb-b-19142) Seropositive rheumatoid arthritis All - Inverse variance weighted -0.6225332075219 0.294797638351753 0.0347095588126056
Coleslaw (ukb-b-2691) Seropositive rheumatoid arthritis All - Inverse variance weighted -0.702756248297944 0.358406545028851 0.049904736716047
Prune (ukb-b-3022) Seropositive rheumatoid arthritis rs118054480 3.91157128994263 1.88548339138071 0.0380262075853743
Prune (ukb-b-3022) Seropositive rheumatoid arthritis All - Inverse variance weighted 1.27065271444036 0.506150470684155 0.0120585988994132
Prune (ukb-b-3022) Seropositive rheumatoid arthritis All - MR Egger 2.30223470333868 0.912855367787945 0.0255067834151345
Pork (ukb-b-5185) Seropositive rheumatoid arthritis rs12200757 4.1295327559024 1.66896451636311 0.0133494441571982
Pork (ukb-b-5185) Seropositive rheumatoid arthritis rs79938133 -3.73892860719638 1.10340562280044 0.0007026705237088
Pork (ukb-b-5185) Seropositive rheumatoid arthritis All - MR Egger -2.25644991475734 0.908164311198242 0.0262338551322977
Pork (ukb-b-5640) Seropositive rheumatoid arthritis rs10896701 -8.07737072846863 3.1046133748357 0.009275441218268
Pork (ukb-b-5640) Seropositive rheumatoid arthritis rs115037803 13.7963651650875 4.97202729360023 0.0055236216474909
Pork (ukb-b-5640) Seropositive rheumatoid arthritis rs13198572 -15.7489927969723 4.07241397352495 0.0001100751292789
Pork (ukb-b-5640) Seropositive rheumatoid arthritis rs55766546 14.7558773816841 6.63606330669945 0.0261761092243011
Pork (ukb-b-5640) Seropositive rheumatoid arthritis All - Inverse variance weighted -0.825891675985993 0.336520302459818 0.0141194283733186
Bread roll (ukb-b-6246) Seropositive rheumatoid arthritis rs115967948 1.35286242221543 0.536531798284101 0.0116857227556234
Bread roll (ukb-b-6246) Seropositive rheumatoid arthritis rs116935289 4.73390466530247 1.63209688560142 0.0037256226717417
Bread roll (ukb-b-6246) Seropositive rheumatoid arthritis rs35522968 3.3474426704862 1.44107771609602 0.0201858957025961
Bread roll (ukb-b-6246) Seropositive rheumatoid arthritis rs9849625 3.07470126482029 1.04819361300692 0.0033534364549463
Bread roll (ukb-b-6246) Seropositive rheumatoid arthritis All - Inverse variance weighted 0.861893810742219 0.274486270389876 0.0016893329245511
Liver (ukb-b-6373) Seropositive rheumatoid arthritis rs139870543 11.83430692985 4.96236183728733 0.017087787007044
Liver (ukb-b-6373) Seropositive rheumatoid arthritis rs58346866 -4.56215778431634 2.20999711364899 0.0389866767176991
Liver (ukb-b-6373) Seropositive rheumatoid arthritis rs73215188 -5.29517977704506 2.01758517820694 0.0086772822390195
Liver (ukb-b-6373) Seropositive rheumatoid arthritis All - Inverse variance weighted -1.40800324726982 0.593728468967859 0.017717969865833
Fortified wine (ukb-b-9524) Seropositive rheumatoid arthritis rs6042162 -6.59910067456007 3.24675753188356 0.0421010082754536
Fortified wine (ukb-b-9524) Seropositive rheumatoid arthritis rs77439809 -11.0100106944371 3.50286645979067 0.0016714408111333
Fortified wine (ukb-b-9524) Seropositive rheumatoid arthritis All - Inverse variance weighted -1.78956177957551 0.595183893994242 0.002640676168909