ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Celery (ukb-b-14145) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 15 -0.648938016 0.281153592 0.020992109
Plum (ukb-b-14182) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 11 -0.646893829 0.309546996 0.036635038
Grapefruit juice (ukb-b-14351) (👉 📊) Seropositive rheumatoid arthritis, wide Weighted median 20 1.597578025 0.785399699 0.041941964
Grapefruit juice (ukb-b-14351) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 20 1.308115201 0.555753493 0.018584169
Cheese (ukb-b-1489) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 198 -0.323727944 0.154773372 0.036472023
Garlic (ukb-b-17223) (👉 📊) Seropositive rheumatoid arthritis, wide MR Egger 19 1.41312938 0.668991567 0.049757017
Cheesecake (ukb-b-1814) (👉 📊) Seropositive rheumatoid arthritis, wide MR Egger 26 2.891631109 1.286447598 0.034050218
Cheesecake (ukb-b-1814) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 26 1.780014949 0.7000533 0.011000438
Espresso (ukb-b-19142) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 33 -0.581221827 0.292999172 0.047289533
Coleslaw (ukb-b-2691) (👉 📊) Seropositive rheumatoid arthritis, wide Weighted median 19 -1.171354047 0.515010764 0.022940365
Coleslaw (ukb-b-2691) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 19 -0.753827428 0.355528927 0.033980885
Prune (ukb-b-3022) (👉 📊) Seropositive rheumatoid arthritis, wide MR Egger 15 2.150702979 0.906382804 0.033756338
Prune (ukb-b-3022) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 15 1.312737234 0.502692547 0.009016925
Pork (ukb-b-5185) (👉 📊) Seropositive rheumatoid arthritis, wide MR Egger 16 -2.260044983 0.91041935 0.026345719
Pork (ukb-b-5640) (👉 📊) Seropositive rheumatoid arthritis, wide Weighted median 82 -1.035480567 0.483521149 0.032230402
Pork (ukb-b-5640) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 82 -0.91707678 0.329311659 0.00535559
Bread roll (ukb-b-6246) (👉 📊) Seropositive rheumatoid arthritis, wide Weighted median 18 0.754357595 0.313656444 0.016170512
Bread roll (ukb-b-6246) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 18 0.818212306 0.2643614 0.001967783
Liver (ukb-b-6373) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 28 -1.312010691 0.575557679 0.022634579
Crispbread (ukb-b-8759) (👉 📊) Seropositive rheumatoid arthritis, wide Weighted median 14 0.418596941 0.205924501 0.042075867
Crispbread (ukb-b-8759) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 14 0.30443043 0.149291031 0.041432637
Fortified wine (ukb-b-9524) (👉 📊) Seropositive rheumatoid arthritis, wide Weighted median 20 -1.69742342 0.801543423 0.034201021
Fortified wine (ukb-b-9524) (👉 📊) Seropositive rheumatoid arthritis, wide Inverse variance weighted 20 -1.859748357 0.590156045 0.001625552

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Celery (ukb-b-14145) Seropositive rheumatoid arthritis, wide rs3110454 -2.82890891244168 1.24626396532519 0.0232129529564645
Celery (ukb-b-14145) Seropositive rheumatoid arthritis, wide rs73169197 -2.87583916229006 1.35673215184575 0.0340329689383513
Celery (ukb-b-14145) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted -0.648938016038988 0.281153591731365 0.0209921094971917
Plum (ukb-b-14182) Seropositive rheumatoid arthritis, wide rs60122509 -1.04649632720039 0.531762556794873 0.0490707174757949
Plum (ukb-b-14182) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted -0.646893829133624 0.309546995556533 0.0366350384051129
Grapefruit juice (ukb-b-14351) Seropositive rheumatoid arthritis, wide rs145263654 4.58326629472924 2.26336822239713 0.0428698302704587
Grapefruit juice (ukb-b-14351) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted 1.30811520066201 0.555753492942438 0.0185841687780669
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs1032001 -6.093529706953 2.19844993348892 0.00557577012727
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs114964798 -3.60895931253588 1.83573835897494 0.0493050482391339
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs11735256 3.66692898883177 1.86695243038695 0.0495155326760878
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs12666766 4.35497050293175 2.11911966740596 0.039870820026394
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs1473781 -5.37976563229217 1.93467912328488 0.0054241543651816
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs1647396 -5.25252525252525 1.87177901463616 0.005013463934366
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs17115145 -4.48736860084158 1.76234026365231 0.0108885457327483
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs2245959 -7.42495094691895 2.14364125126414 0.0005327811895723
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs281219 -5.24432608550111 1.98614902812595 0.0082796146120919
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs34423638 -5.59972642557921 2.21566783505742 0.0114933062179854
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs6126641 3.65945864206865 1.73899894147891 0.0353481170091446
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs61953351 3.77573116245923 1.699421648439 0.0262985695794747
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs62034322 -4.57105952423666 1.60022962936385 0.0042833697905158
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs62048491 -4.60844689568752 2.06102276193538 0.0253517711582223
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs6544743 -3.82048261906919 1.94799311407085 0.0498509966177808
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs6694085 4.55001769451326 2.04389683737659 0.0260042422483333
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs67238148 4.06813675709657 1.65626964553412 0.0140413275186023
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs6857 4.23002925440793 1.88440555570197 0.0247838493546031
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide rs78548855 5.4199859533663 1.73484320654987 0.0017829313549862
Cheese (ukb-b-1489) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted -0.32372794401095 0.154773372247665 0.03647202271358
Garlic (ukb-b-17223) Seropositive rheumatoid arthritis, wide All - MR Egger 1.41312937977189 0.668991567209233 0.0497570169410911
Cheesecake (ukb-b-1814) Seropositive rheumatoid arthritis, wide rs28694319 8.32219504198926 3.34569053203204 0.0128667173059092
Cheesecake (ukb-b-1814) Seropositive rheumatoid arthritis, wide rs73084384 8.86890549723796 3.92760769132959 0.023939829232071
Cheesecake (ukb-b-1814) Seropositive rheumatoid arthritis, wide rs79910083 9.69537855029398 2.65704867105358 0.0002633371760452
Cheesecake (ukb-b-1814) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted 1.78001494927985 0.700053299639779 0.0110004383905435
Cheesecake (ukb-b-1814) Seropositive rheumatoid arthritis, wide All - MR Egger 2.89163110891666 1.28644759817787 0.0340502184946781
Espresso (ukb-b-19142) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted -0.581221827099052 0.292999171576581 0.0472895332498727
Coleslaw (ukb-b-2691) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted -0.753827427672217 0.355528926583704 0.0339808853248414
Prune (ukb-b-3022) Seropositive rheumatoid arthritis, wide rs118054480 3.90235132225862 1.8739584317757 0.0373049606007774
Prune (ukb-b-3022) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted 1.31273723424547 0.502692547001537 0.00901692513225
Prune (ukb-b-3022) Seropositive rheumatoid arthritis, wide All - MR Egger 2.15070297909349 0.906382803975112 0.0337563383346987
Pork (ukb-b-5185) Seropositive rheumatoid arthritis, wide rs12200757 4.10974266282299 1.65577112097684 0.0130620984607576
Pork (ukb-b-5185) Seropositive rheumatoid arthritis, wide rs79938133 -3.7283865152588 1.09462054618578 0.0006589815324385
Pork (ukb-b-5185) Seropositive rheumatoid arthritis, wide All - MR Egger -2.26004498334782 0.91041935041027 0.0263457191393664
Pork (ukb-b-5640) Seropositive rheumatoid arthritis, wide rs10896701 -7.55321522362624 3.0777336053566 0.014121866132474
Pork (ukb-b-5640) Seropositive rheumatoid arthritis, wide rs115037803 13.7680690747987 4.94777350192413 0.0053911994126719
Pork (ukb-b-5640) Seropositive rheumatoid arthritis, wide rs13198572 -15.9757224828645 4.02881211085337 7.32828088074347e-05
Pork (ukb-b-5640) Seropositive rheumatoid arthritis, wide rs55766546 13.5842424708052 6.54963122311002 0.0380749534252156
Pork (ukb-b-5640) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted -0.917076779844818 0.32931165896215 0.0053555897495317
Bread roll (ukb-b-6246) Seropositive rheumatoid arthritis, wide rs115967948 1.32578511650763 0.533523208761013 0.0129565116513041
Bread roll (ukb-b-6246) Seropositive rheumatoid arthritis, wide rs116935289 4.53268724105024 1.61444623435123 0.0049915252947562
Bread roll (ukb-b-6246) Seropositive rheumatoid arthritis, wide rs35522968 3.17824731110651 1.4367019740431 0.0269540408676773
Bread roll (ukb-b-6246) Seropositive rheumatoid arthritis, wide rs9849625 2.93028347813934 1.03887633644686 0.0047929777260234
Bread roll (ukb-b-6246) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted 0.818212306494242 0.264361399807405 0.0019677832616271
Liver (ukb-b-6373) Seropositive rheumatoid arthritis, wide rs139870543 12.2302740262616 4.97726382478669 0.0140013637501269
Liver (ukb-b-6373) Seropositive rheumatoid arthritis, wide rs73215188 -4.48265033757262 2.02151044119956 0.0265905998723586
Liver (ukb-b-6373) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted -1.31201069066681 0.575557678948958 0.0226345786631891
Crispbread (ukb-b-8759) Seropositive rheumatoid arthritis, wide rs79252206 2.13864856801909 1.04042362768496 0.0398253754995506
Crispbread (ukb-b-8759) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted 0.304430430299138 0.149291031235811 0.0414326374412456
Fortified wine (ukb-b-9524) Seropositive rheumatoid arthritis, wide rs6042162 -6.53310966781447 3.22036112918531 0.0424900254521254
Fortified wine (ukb-b-9524) Seropositive rheumatoid arthritis, wide rs77439809 -11.020529812935 3.46780273146444 0.0014831647304989
Fortified wine (ukb-b-9524) Seropositive rheumatoid arthritis, wide All - Inverse variance weighted -1.85974835734451 0.590156045496545 0.0016255523889866