ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Spondyloarthritis (finn-b-SPONDYLOARTHRITIS)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Tinned tomato (ukb-b-10565) (👉 📊) Spondyloarthritis Weighted median 13 1.330817622 0.560957119 0.017672695
Tinned tomato (ukb-b-10565) (👉 📊) Spondyloarthritis Inverse variance weighted 13 1.021972636 0.485892129 0.035440323
Pineapple (ukb-b-1164) (👉 📊) Spondyloarthritis Weighted median 16 -2.108998663 0.905983376 0.019919762
Pineapple (ukb-b-1164) (👉 📊) Spondyloarthritis Inverse variance weighted 16 -2.322357121 0.648446428 0.000341736
Side salad (ukb-b-1604) (👉 📊) Spondyloarthritis Weighted median 17 -0.504803483 0.237203771 0.033325251
Side salad (ukb-b-1604) (👉 📊) Spondyloarthritis Inverse variance weighted 17 -0.435637404 0.169067124 0.009974482
Dark chocolate (ukb-b-16139) (👉 📊) Spondyloarthritis MR Egger 21 -1.489305354 0.631233485 0.029162325
Fruit smoothie (ukb-b-1780) (👉 📊) Spondyloarthritis MR Egger 24 -1.709457579 0.752287088 0.03318898
Cheesecake (ukb-b-1814) (👉 📊) Spondyloarthritis Simple mode 26 3.803978234 1.83838262 0.049013921
Milk (ukb-b-2966) (👉 📊) Spondyloarthritis MR Egger 20 -2.633895134 1.07072406 0.024241253
Cabbage/kale (ukb-b-2975) (👉 📊) Spondyloarthritis Inverse variance weighted 20 -0.704452637 0.283079462 0.012827126
Green tea (ukb-b-4078) (👉 📊) Spondyloarthritis Weighted mode 126 0.010448754 0.005215238 0.047285542
Sushi (ukb-b-5213) (👉 📊) Spondyloarthritis Weighted median 69 1.939096442 0.980732151 0.048019853
Sausage (ukb-b-5847) (👉 📊) Spondyloarthritis MR Egger 12 2.814512211 0.913081649 0.011592513
Garlic bread (ukb-b-602) (👉 📊) Spondyloarthritis MR Egger 23 1.929122743 0.783015197 0.022468289
Bread roll (ukb-b-6246) (👉 📊) Spondyloarthritis Weighted median 18 0.744834986 0.371818973 0.045153742
Bread roll (ukb-b-6246) (👉 📊) Spondyloarthritis Inverse variance weighted 18 0.52519234 0.264959179 0.047460975
Poultry (ukb-b-8006) (👉 📊) Spondyloarthritis Weighted median 80 0.98007429 0.489020824 0.045053293
Poultry (ukb-b-8006) (👉 📊) Spondyloarthritis Inverse variance weighted 80 0.73768997 0.326611827 0.02390742
Stewed fruit (ukb-b-8676) (👉 📊) Spondyloarthritis MR Egger 9 3.888538203 1.485609436 0.034536021
Squash (ukb-b-8793) (👉 📊) Spondyloarthritis MR Egger 18 1.655184989 0.72492883 0.036425029

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Tinned tomato (ukb-b-10565) Spondyloarthritis rs142793391 4.93421871964372 1.43219372225903 0.0005706002880452
Tinned tomato (ukb-b-10565) Spondyloarthritis All - Inverse variance weighted 1.02197263580789 0.485892129241296 0.0354403229044712
Pineapple (ukb-b-1164) Spondyloarthritis rs111799849 -4.24751423882614 2.13754775005861 0.0469116736592972
Pineapple (ukb-b-1164) Spondyloarthritis rs72771953 -5.77277645933281 2.05274915126718 0.0049201268107723
Pineapple (ukb-b-1164) Spondyloarthritis rs75055053 -5.64168654872111 2.76628436105614 0.0414055724122113
Pineapple (ukb-b-1164) Spondyloarthritis All - Inverse variance weighted -2.32235712111976 0.648446428473445 0.0003417355883741
Side salad (ukb-b-1604) Spondyloarthritis rs5769096 -1.23584735215 0.544525635363552 0.0232327591905571
Side salad (ukb-b-1604) Spondyloarthritis All - Inverse variance weighted -0.435637403501241 0.169067123757792 0.0099744819215862
Dark chocolate (ukb-b-16139) Spondyloarthritis rs78920357 -4.54728554046254 2.08884440808462 0.0294851660939031
Dark chocolate (ukb-b-16139) Spondyloarthritis All - MR Egger -1.4893053541363 0.631233485391158 0.0291623251671384
Fruit smoothie (ukb-b-1780) Spondyloarthritis rs685117 -2.55951677605029 0.965326358416464 0.0080146437142563
Fruit smoothie (ukb-b-1780) Spondyloarthritis All - MR Egger -1.7094575794428 0.75228708809638 0.0331889800612044
Milk (ukb-b-2966) Spondyloarthritis rs191749866 -3.20232082844133 1.46915397851867 0.0292794086206474
Milk (ukb-b-2966) Spondyloarthritis All - MR Egger -2.63389513383674 1.07072405994384 0.0242412530622668
Cabbage/kale (ukb-b-2975) Spondyloarthritis rs72652073 -2.93276142893308 1.33263915093213 0.0277560754833219
Cabbage/kale (ukb-b-2975) Spondyloarthritis rs758166 -1.54646029317937 0.75646937751621 0.0409226213454646
Cabbage/kale (ukb-b-2975) Spondyloarthritis All - Inverse variance weighted -0.704452637161321 0.283079462384839 0.0128271264300904
Green tea (ukb-b-4078) Spondyloarthritis rs117914662 -0.0957356118069885 0.0354074031019016 0.0068545271330556
Green tea (ukb-b-4078) Spondyloarthritis rs17313318 -0.158561310197741 0.057189499460228 0.005561729049486
Green tea (ukb-b-4078) Spondyloarthritis rs56158811 0.317528587857991 0.122065244831745 0.0092870608488737
Green tea (ukb-b-4078) Spondyloarthritis rs708262 -0.123890021860192 0.0474339630295947 0.0090055835684032
Green tea (ukb-b-4078) Spondyloarthritis rs75495430 -0.25954293954912 0.0966802048384248 0.0072627304088684
Green tea (ukb-b-4078) Spondyloarthritis rs75897995 -0.0743210856444854 0.0376244053540044 0.0482292971723073
Sushi (ukb-b-5213) Spondyloarthritis rs113377951 11.8612313456942 5.32980166677434 0.0260507393149405
Sushi (ukb-b-5213) Spondyloarthritis rs146729456 -21.9467247445133 10.4027056458368 0.0348830723914178
Sushi (ukb-b-5213) Spondyloarthritis rs17452433 -22.3205432727689 10.0695836877151 0.0266483723175808
Sushi (ukb-b-5213) Spondyloarthritis rs57321543 53.889711647356 20.8032058541685 0.0095849914767215
Sushi (ukb-b-5213) Spondyloarthritis rs77376288 -4.9919044515003 2.36347961393696 0.0346779035254576
Sausage (ukb-b-5847) Spondyloarthritis rs4245952 -2.41767806198927 1.00160948282412 0.0157874242343648
Sausage (ukb-b-5847) Spondyloarthritis All - MR Egger 2.81451221064667 0.913081649040912 0.0115925132155661
Garlic bread (ukb-b-602) Spondyloarthritis rs72763074 -5.95012198427758 2.4329086473299 0.0144578276182169
Garlic bread (ukb-b-602) Spondyloarthritis All - MR Egger 1.92912274250439 0.783015196989195 0.022468288802403
Bread roll (ukb-b-6246) Spondyloarthritis All - Inverse variance weighted 0.52519234049464 0.264959178782667 0.0474609750615246
Poultry (ukb-b-8006) Spondyloarthritis rs11678980 6.1630891750789 2.90336003655928 0.0337753364034783
Poultry (ukb-b-8006) Spondyloarthritis rs11976316 5.40395341855357 2.6861756758892 0.0442447460680794
Poultry (ukb-b-8006) Spondyloarthritis rs2965200 -6.21898903039435 2.91755040932081 0.0330414759684301
Poultry (ukb-b-8006) Spondyloarthritis All - Inverse variance weighted 0.737689970440059 0.326611826595536 0.0239074202337041
Stewed fruit (ukb-b-8676) Spondyloarthritis All - MR Egger 3.8885382028238 1.48560943637059 0.0345360211277121
Squash (ukb-b-8793) Spondyloarthritis All - MR Egger 1.65518498867327 0.724928829644469 0.0364250290050421