ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Burn and corrosion of hip and lower limb, except ankle and foot (finn-b-ST19_BURN_CORROSION_HIP_LOWER_LIMB_ANKLE_FOOT)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Bread (ukb-b-11348) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot MR Egger 113 -9.274374767 2.911385024 0.001876036
Bread (ukb-b-11348) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Inverse variance weighted 113 -1.856362961 0.841273684 0.027341315
Pineapple (ukb-b-1164) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Weighted median 16 -5.421994485 2.743291585 0.04810318
Fried potatoes (ukb-b-12836) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Weighted median 16 -1.703046174 0.854223156 0.046187222
Fried potatoes (ukb-b-12836) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Inverse variance weighted 16 -1.418507307 0.702581982 0.043488065
Sweetcorn (ukb-b-13567) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Weighted median 20 -4.157453832 1.746198569 0.017272288
Sweetcorn (ukb-b-13567) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Inverse variance weighted 20 -3.787588971 1.245409356 0.002356058
Shellfish (ukb-b-143) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot MR Egger 40 10.07783996 4.782733205 0.041762177
White rice (ukb-b-14690) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Inverse variance weighted 14 -2.96620245 1.485232926 0.04581112
Espresso (ukb-b-19142) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Simple mode 33 6.946623504 3.146728192 0.034562948
Oily fish (ukb-b-2209) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot MR Egger 168 5.972389603 2.50445798 0.018220734
Porridge (ukb-b-29) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Inverse variance weighted 14 2.713029904 1.210171909 0.024970747
Prune (ukb-b-3022) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Weighted median 15 6.576111467 2.680874384 0.014168112
Prune (ukb-b-3022) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Inverse variance weighted 15 7.076368868 1.933000839 0.000251409
Ham (ukb-b-4442) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Inverse variance weighted 9 2.401257357 0.993495105 0.015649896
Mango (ukb-b-6218) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot MR Egger 25 -7.667539916 2.874336874 0.013752183
Mango (ukb-b-6218) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Weighted median 25 -6.511603566 2.63095658 0.013323816
Mango (ukb-b-6218) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Inverse variance weighted 25 -4.8137767 1.728016382 0.005340833
Mango (ukb-b-6218) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Weighted mode 25 -6.030107342 2.335006886 0.016338044
Couscous (ukb-b-758) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot MR Egger 17 13.43604699 5.916298007 0.038307243
Yogurt (ukb-b-7753) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Inverse variance weighted 9 -3.132353543 1.430999738 0.028602168
Cooked vegetable (ukb-b-8089) (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot Inverse variance weighted 94 2.218939582 1.067605088 0.037670019

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Bread (ukb-b-11348) Burn and corrosion of hip and lower limb, except ankle and foot rs146642700 -43.3434326925898 16.5256527915719 0.008721121641476
Bread (ukb-b-11348) Burn and corrosion of hip and lower limb, except ankle and foot rs1940033 -17.1495622348587 7.78048560339381 0.0275119454460355
Bread (ukb-b-11348) Burn and corrosion of hip and lower limb, except ankle and foot rs379336 22.2710376898517 8.96503635820301 0.0129839022585131
Bread (ukb-b-11348) Burn and corrosion of hip and lower limb, except ankle and foot rs7211048 -24.5616943849267 9.07645478352549 0.0068080798747226
Bread (ukb-b-11348) Burn and corrosion of hip and lower limb, except ankle and foot rs72823602 -19.9669354268336 8.39875521606903 0.0174366626605801
Bread (ukb-b-11348) Burn and corrosion of hip and lower limb, except ankle and foot rs7802468 -9.84896821352563 3.85822624364635 0.0106885628770481
Bread (ukb-b-11348) Burn and corrosion of hip and lower limb, except ankle and foot rs79436018 -16.6111259345887 7.76056362015816 0.0323181310039772
Bread (ukb-b-11348) Burn and corrosion of hip and lower limb, except ankle and foot rs9755262 -22.8616588747227 9.33605019852794 0.0143352654936571
Bread (ukb-b-11348) Burn and corrosion of hip and lower limb, except ankle and foot All - Inverse variance weighted -1.85636296139531 0.841273683868513 0.0273413145847128
Bread (ukb-b-11348) Burn and corrosion of hip and lower limb, except ankle and foot All - MR Egger -9.27437476737346 2.91138502370932 0.001876036086234
Pineapple (ukb-b-1164) Burn and corrosion of hip and lower limb, except ankle and foot rs3096085 27.5104254205845 12.2568062536667 0.0248001242097552
Fried potatoes (ukb-b-12836) Burn and corrosion of hip and lower limb, except ankle and foot All - Inverse variance weighted -1.41850730689214 0.702581982293702 0.0434880650179636
Sweetcorn (ukb-b-13567) Burn and corrosion of hip and lower limb, except ankle and foot rs1841715 -10.8007380299993 5.3145515732176 0.0421237729274338
Sweetcorn (ukb-b-13567) Burn and corrosion of hip and lower limb, except ankle and foot rs4710195 -13.2056170371059 5.48064106140922 0.0159742970209517
Sweetcorn (ukb-b-13567) Burn and corrosion of hip and lower limb, except ankle and foot All - Inverse variance weighted -3.7875889706856 1.24540935575475 0.0023560580988677
Shellfish (ukb-b-143) Burn and corrosion of hip and lower limb, except ankle and foot rs12487739 -56.6505626525188 21.3402886866831 0.0079395527654185
Shellfish (ukb-b-143) Burn and corrosion of hip and lower limb, except ankle and foot rs182535176 19.8599402962657 8.08441131742485 0.0140269602983845
Shellfish (ukb-b-143) Burn and corrosion of hip and lower limb, except ankle and foot rs75715109 -30.3348240632664 14.5706828942019 0.0373508564844185
Shellfish (ukb-b-143) Burn and corrosion of hip and lower limb, except ankle and foot All - MR Egger 10.077839955192 4.7827332050662 0.0417621771074297
White rice (ukb-b-14690) Burn and corrosion of hip and lower limb, except ankle and foot All - Inverse variance weighted -2.96620244968939 1.48523292593274 0.0458111200615984
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs10137526 19.1565165502475 8.99469970865948 0.033191754954763
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs1263459 -24.4849517732324 9.58920548313192 0.0106680915791266
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs12966327 -20.7542554829826 8.01724840787412 0.0096338826223306
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs275160 -16.1484635442453 7.55025250024755 0.0324520465765415
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs4261301 -21.1752850606435 9.77058973055414 0.0302159958984046
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs4851487 -22.7523039006732 9.8560859978665 0.0209739957289591
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs56096330 21.003154877248 10.489566484634 0.0452535426844465
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs6769454 19.5536461706127 8.61592405982974 0.0232393013279839
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs730925 17.1698095119403 8.30209661493035 0.0386278633376143
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs77424805 17.3638553986023 7.83169753840406 0.026614524747573
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs8182438 -22.3013580835413 8.34665245959865 0.0075424807570678
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs9597870 19.2939921066466 8.0032012805122 0.0159182590070329
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot rs9889161 19.5268804288256 7.13207858799859 0.0061833863994712
Oily fish (ukb-b-2209) Burn and corrosion of hip and lower limb, except ankle and foot All - MR Egger 5.97238960270059 2.50445797957028 0.018220733581807
Porridge (ukb-b-29) Burn and corrosion of hip and lower limb, except ankle and foot rs1186256 12.1454782362953 5.5549922661564 0.0287857858778987
Porridge (ukb-b-29) Burn and corrosion of hip and lower limb, except ankle and foot rs139125030 -14.8779524144511 6.41990536855191 0.0204780216536532
Porridge (ukb-b-29) Burn and corrosion of hip and lower limb, except ankle and foot All - Inverse variance weighted 2.71302990390925 1.2101719090747 0.0249707474162526
Prune (ukb-b-3022) Burn and corrosion of hip and lower limb, except ankle and foot rs11247295 18.5420649658339 8.15960628984898 0.0230610628666561
Prune (ukb-b-3022) Burn and corrosion of hip and lower limb, except ankle and foot All - Inverse variance weighted 7.07636886813402 1.93300083944117 0.0002514089684284
Ham (ukb-b-4442) Burn and corrosion of hip and lower limb, except ankle and foot All - Inverse variance weighted 2.40125735701227 0.99349510508 0.0156498961211177
Mango (ukb-b-6218) Burn and corrosion of hip and lower limb, except ankle and foot rs71559841 -7.07636494109674 2.27683979951407 0.0018837294813831
Mango (ukb-b-6218) Burn and corrosion of hip and lower limb, except ankle and foot All - Inverse variance weighted -4.81377670049539 1.728016382056 0.005340832551993
Mango (ukb-b-6218) Burn and corrosion of hip and lower limb, except ankle and foot All - MR Egger -7.66753991566128 2.87433687379662 0.0137521831162898
Couscous (ukb-b-758) Burn and corrosion of hip and lower limb, except ankle and foot rs56200810 -25.7635432271783 12.9723819649157 0.0470299631643337
Couscous (ukb-b-758) Burn and corrosion of hip and lower limb, except ankle and foot All - MR Egger 13.4360469942251 5.91629800669592 0.0383072432619643
Yogurt (ukb-b-7753) Burn and corrosion of hip and lower limb, except ankle and foot rs149870452 -11.1784878273534 4.37347384522459 0.0105890864421005
Yogurt (ukb-b-7753) Burn and corrosion of hip and lower limb, except ankle and foot rs150992808 -13.2510896637609 5.68032139093783 0.0196583126110329
Yogurt (ukb-b-7753) Burn and corrosion of hip and lower limb, except ankle and foot All - Inverse variance weighted -3.13235354269523 1.43099973777558 0.0286021676316195
Cooked vegetable (ukb-b-8089) Burn and corrosion of hip and lower limb, except ankle and foot rs10161952 23.5808680765778 9.36345226413913 0.0117891145482339
Cooked vegetable (ukb-b-8089) Burn and corrosion of hip and lower limb, except ankle and foot rs1352243 19.9364937471483 9.83322624800961 0.0426151744695621
Cooked vegetable (ukb-b-8089) Burn and corrosion of hip and lower limb, except ankle and foot rs333537 23.0810162723887 11.6357717646771 0.0472975785469374
Cooked vegetable (ukb-b-8089) Burn and corrosion of hip and lower limb, except ankle and foot rs6088332 25.7481679361756 9.9274394426194 0.0094966870808754
Cooked vegetable (ukb-b-8089) Burn and corrosion of hip and lower limb, except ankle and foot rs62485872 20.7394833627125 10.5329590215664 0.0489521420521518
Cooked vegetable (ukb-b-8089) Burn and corrosion of hip and lower limb, except ankle and foot All - Inverse variance weighted 2.21893958163617 1.06760508765309 0.037670018553411